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胃がん治療の世界市場-2023年~2030年Global Stomach Cancer Treatment Market - 2023-2030 |
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胃がん治療の世界市場-2023年~2030年 |
出版日: 2023年09月06日
発行: DataM Intelligence
ページ情報: 英文 195 Pages
納期: 約2営業日
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概要
胃がん治療の世界市場は、2022年に47億米ドルに達し、2023~2030年の予測期間中にCAGR 8.7%で成長し、2030年には103億米ドルに達すると予測されます。
胃がんは、胃の粘膜に悪性(がん)細胞ができる病気です。胃がんは通常、胃を覆う粘液産生細胞から始まります。胃がんの症状には、消化不良や胃の不快感、痛みなどがあります。ほとんどの人は初期の段階では徴候を示さないのが普通で、そのため診断が難しくなります。このため、胃がんは他の体の部位に転移して転移を起こすまで診断されないことが多いです。
胃がんは世界中で死因の第3位を占めています。米国国立がん研究所によると、がんによる死亡者の1.8%が胃がんによるものです。米国がん学会の2022年の推計によると、胃がんは毎年米国で新たに発生するがんの約1.5%を占めています。
さらに、胃がんの罹患率の上昇、座りがちなライフスタイルや不規則な食習慣の採用、腫瘍学分野における研究開発の高まりは、今後一定期間の市場を牽引すると予想されるいくつかの要因です。
ダイナミクス
製品上市の増加
胃がんは現在、世界で5番目に多く診断されるがんであり、がん関連死因の第4位を占めています。症例の90~95%以上が腺がんに分類されます。米国がん協会の2022年の推定では、胃がんによる新規症例は26,380例、死亡は11,090例となっています。
例えば、2023年2月、Enhertu社は韓国で胃がん3次治療を開始しました。最初で唯一のHER2標的ADCで、進行・転移性胃がんの治療を改善します。
さらに、2023年4月、HUTCHMED(China)Limitedは、パクリタキセルとともに進行性胃がんまたは胃食道接合部腺がんの二次治療を適応とするフルキンチニブの新薬承認申請(「NDA」)を中国国家医薬品監督管理局(「NMPA」)に受理されました。
医薬品パイプラインの増加
様々なバイオテクノロジー企業や製薬企業が、パイプラインにある様々な医薬品を開発しています。CNBG-Virogin Biotech、Minneamrita Therapeutics LLCなどです。これらの薬剤は胃がんの治療における安全性と有効性が試験されています。治療効果を観察するために、併用薬が患者に投与されます。
浙江省がん病院はCSPC Ouyi Pharmaceutical Co., Ltd.と共に、ステージ3の胃がんに対する術後補助療法として、アルブミン結合パクリタキセル+S-1とオキサリプラチン+カペシタビン(XELOX)の有効性と安全性を比較する第3相臨床試験を実施しています。終了予定日は2024年10月31日です。
放射線療法と化学療法に関連する合併症
化学療法と放射線療法は胃がんの主要な治療法です。化学療法はまた、日光過敏症や日焼けのリスクの増加などの影響をもたらす可能性があります。化学療法によって一時的に乳糖不耐症になることもあります。胃がんに対する化学療法と放射線療法はともに、下痢、吐き気、嘔吐を引き起こすことがあります。骨盤に放射線を照射したり、化学療法薬の中には尿路感染症(UTI)を引き起こすものもあります。胃がんの治療とは別に、エストロゲンレベルを低下させ、膣乾燥症などの症状や原発性卵巣機能不全、テストステロンレベル、精子数などの状態を引き起こすことがあります。
Global Stomach Cancer Treatment Market reached US$ 4.7 billion in 2022 and is expected to reach US$ 10.3 billion by 2030 growing with a CAGR of 8.7% during the forecast period 2023-2030.
Stomach cancer is a disease in which malignant (cancer) cells are formed in the stomach lining. Stomach cancer usually begins in the mucus-producing cells that line the stomach. Symptoms of stomach cancer include indigestion and stomach discomfort or pain. Most people typically do not show signs in the earlier stages due to which diagnosis becomes difficult. Because of this, it often goes undiagnosed until after it spreads to other body parts and cause metastasis.
Gastric cancer is the third leading cause of death throughout the world. According to the National Cancer Institute, 1.8% of the deaths caused by cancer are due to stomach cancer. According to the American Cancer Society estimate in 2022, stomach cancer accounts for about 1.5% of all new cancers in the U.S. annually.
Furthermore, the rising incidence of gastric cancer, the adoption of a sedentary lifestyle and irregular food habits, and rising research and development in the oncology sector are a few factors that are expected to drive the market in the forthcoming period.
Gastric cancer is currently the fifth most frequently diagnosed cancer and the fourth leading cancer-related cause of death worldwide. Over 90-95% of cases are classified as adenocarcinoma. The American Cancer Society's 2022 estimates include 26,380 new cases and 11,090 deaths from gastric cancer.
For instance, in February 2023, Enhertu launched gastric cancer tertiary treatment in South Korea. The first and only HER2 target ADC, which improves treatment for advanced and metastatic gastric cancer.
Additionally, in April 2023, HUTCHMED (China) Limited was granted a New Drug Application ("NDA") for fruquintinib along with paclitaxel for the treatment of second-line progressive gastric or gastroesophageal junction adenocarcinoma in China was accepted for consideration by the China National Medical Products Administration ("NMPA").
Various biotech and pharmaceutical companies are developing various drugs which are in the pipeline. Companies like CNBG-Virogin Biotech, Minneamrita Therapeutics LLC, etc. These drugs are tested for safety and efficacy in treating gastric cancer. Combination drugs are given to the patients to observe the effectiveness of the therapy.
Zhejiang Cancer Hospital along with CSPC Ouyi Pharmaceutical Co., Ltd. are conducting a phase 3 clinical trial to compare the efficacy and safety of Albumin-bound Paclitaxel plus S-1 versus Oxaliplatin plus capecitabine (XELOX) treating stage 3 gastric cancer as adjuvant setting. The estimated completion date is October 31, 2024.
Chemotherapy and radiotherapy are the leading treatments for stomach cancer. Chemotherapy may also lead to implications such as sunlight sensitivity and increasing sunburn risk. Chemotherapy can cause individuals to become temporarily lactose intolerant. Both chemotherapy and radiation therapy for stomach cancer can cause diarrhea, nausea, and vomiting. Radiation toward the pelvis and some chemotherapy drugs lead to urinary tract infections (UTIs). Apart from treating stomach cancer, it can decrease estrogen levels, causing symptoms like vaginal dryness and conditions like primary ovarian insufficiency, testosterone levels, and sperm count.
Chemotherapy can target cancer cells that have spread beyond the stomach or shrink the tumor before surgery and alleviate symptoms in advanced cases of gastric cancer. The use of chemotherapy in gastric cancer is rapidly evolving, and the optimal treatment strategy may vary depending on the tumor's molecular characteristics, the stage of cancer, and other individual factors.
Due to the increased use of chemotherapy treatment for stomach cancer, there is an increase in chemotherapeutic products in the market. For instance, in April 2022, BDR Pharmaceuticals launched Furmecil, a generic oral drug for treating advanced gastric cancer.
Furthermore, in June 2023, Merck & Co.'s Keytruda, in a new phase 3 trial, Keytruda plus chemotherapy, significantly extended patients' lives over chemo alone in newly diagnosed HER2-negative gastric or gastroesophageal junction cancers that are advanced or metastatic. The Keytruda combination cut the risk of death by 22%.
North America accounts for the largest market share for stomach cancer treatment. The American Cancer Society's estimates for stomach cancer (also known as gastric cancer) in the United States for 2023 are about 26,500 new cases of stomach cancer (15,930 in men and 10,570 in women).
In addition to that, lifestyle factors such as improper diet and smoking cause gastric cancer. Diets high in salt, smoked or pickled foods, and low in fruits and vegetables have been linked to an increase in the risk of gastric cancer. Similarly, smoking is a most common risk factor for gastric cancer and the prevalence of smoking in many countries in North America remains high. All these factors are anticipated to boost the growth of the North American gastric cancer market during the forecast period.
The COVID-19 pandemic has also had a massive impact on secondary care. Hospitals and health centers reduced their functioning capacity to maintain social distancing measures by government guidelines, which consequently delayed cancer diagnosis. A March 2021 report noted a 60% decrease in new oncology clinical trials during the pandemic, fueling concerns regarding slowing the development of new cancer therapies. A major UK-based cancer research charity, Cancer Research UK, halted recruitment in 95% of their clinical trials to protect cancer patients including stomach cancer, and cope with the redeployment of clinical research staff to support frontline COVID-19-facing healthcare services.
The major global players in the stomach cancer treatment market include: Merck & Co., Inc, Bristol-Myers Squibb, Accord Healthcare, Sanofi S.A, Bayer Pharma AG, Eli Lilly and Company, Teva Pharmaceutical Industries Ltd, Celltrion, Inc., Genentech, Inc., and Winthrop US among others.
The global stomach cancer treatment market report would provide approximately 53 tables, 54 figures, and 195 Pages.
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