細胞培養タンパク質表面コーティングの世界市場-2023-2030

市場概要

細胞培養タンパク質表面コーティングの世界市場規模は、2022年に8億4,340万米ドル、2030年には18億1,050万米ドルに達すると推定され、予測期間（2023-2030年）に10.3%のCAGRで成長すると予測されています。主要な主要プレーヤーによる製品発売の増加は、予測期間中の細胞培養タンパク質表面コーティング市場の成長を後押しするのに役立ちます。例えば、2020年6月、Corning Incorporatedは、Matrigel matrix-3D platesを含む新製品を発売しました。

追加の表面処理としてのコーティングは、細胞の接着性を高めるために行われるすべての追加の修正と、メーカーがすべての細胞培養プラスチックに行う標準的なプラズマ処理またはコロナ処理を意味します。通常、コーティングはタンパク質またはペプチドで行われます。細胞培養の欠点は、高度に熟練した人材、動物細胞は一般的な汚染物質（細菌、ウイルス、真菌）の多くよりも成長が遅いため、厳格な無菌技術で実施する必要があることです。

市場力学

3D細胞培養の採用が増加し、細胞培養タンパク質表面コーティング市場の成長を促進する

3D細胞培養の追加的な次元性は、細胞反応の違いをもたらす重要な特徴です。これは、周囲の細胞との相互作用に関与する細胞表面の受容体の空間構成に影響を与えるだけでなく、細胞に物理的な制約をもたらすものです。

3次元培養におけるこれらの空間的・物理的側面は、細胞の外側から内側へのシグナル伝達に影響を与え、最終的に遺伝子発現や細胞の挙動に影響を与えます。3次元培養における細胞の反応は、2次元培養と比較して、より生体内の挙動に近いことが実証されています。

微生物汚染のリスクなどが市場成長を阻害する要因となっている

細胞培養は、汚染を防ぐために常に監視する必要があり、細胞培養のタンパク質表面コーティングの無駄を避けるために、もともと高価であることもあり、市場成長に影響を与えます。

さらに、組織組成は可変的で不均一です。同じサンプルからのレプリカは様々な成分を有しています。実験結果を再現するためには、細胞株を連続継代で何度も操作する必要があります。

例えば、どの培養物もオリジナルとは異なり、その構成は均一ではなくなります。この問題を解決するために、レプリカは各継代でランダムに混合され、生育条件の選択圧によって最適な優勢な表現型が生み出される傾向にあります。これらの欠点は、細胞培養タンパク質表面コーティング市場の成長を妨げるでしょう。

COVID-19の影響度分析

2022年7月にJournal of Clinical Virologyが発表した報告によると、SARS-CoV-2を培養で分離する確率、症状発現日数の少なさ、RT-PCRサイクル閾値の低さの間には有意な正の相関があっています。

したがって、COVID-19では、適切な診断のために細胞培養が使用され、細胞培養タンパク質表面コーティング市場の成長を促進することが期待されました。ウイルス研究はまだ進行中であるため、今後大きな影響を与えることが予想されます。

ロシア・ウクライナ紛争分析

ロシアとウクライナの紛争は、培養に使用される一部の機器のサプライチェーンに混乱をもたらし、消費者のコストを増加させ、必要な機器へのアクセスをより困難にしています。これらの要因は、細胞培養タンパク質表面コーティング市場に大きな影響を与えています。

目次

第1章 調査手法とスコープ

• 調査手法
• 調査目的および調査範囲

第2章 定義と概要

第3章 エグゼクティブサマリー

• コーティングタイプ別
• タンパク質源別
• 地域別

第4章 市場力学

• 影響分析
  • 促進要因
    • 3D細胞培養の普及が、細胞培養タンパク質の表面コーティングを促進します
  • 抑制要因
    • 遺伝子変異などのリスク要因
  • 機会
  • 影響分析

第5章 産業分析

• ポーターのファイブフォース分析
• サプライチェーン分析
• 価格分析
• 法規制の分析

第6章 COVID-19の分析

• COVID-19の分析
  • COVID-19登場前シナリオ
  • 現在のCOVID-19シナリオ
  • COVID-19後または将来のシナリオ
• COVID-19の中での価格・ダイナミクス
• 需給スペクトル
• パンデミック時の市場に関連する政府の取り組み
• メーカーの戦略的な取り組み
• サマリー

第7章 コーティングタイプ別

• プレコート
  • マルチウォール・マイクロウェルプレート
• フラスコ
• ペトリ皿
• セルフコーティング

第8章 タンパク質源別

• 動物由来
• 合成
• ヒト由来
• 植物由来

第9章 地域別

• 北米
  • 米国
  • カナダ
  • メキシコ
• 欧州
  • ドイツ
  • 英国
  • フランス
  • イタリア
  • スペイン
  • その他欧州
• 南米
  • ブラジル
  • アルゼンチン
  • その他南米地域
• アジア太平洋地域
  • 中国
  • インド
  • 日本
  • オーストラリア
  • その他アジア太平洋地域
• 中東・アフリカ地域

第10章 競合情勢

• 競合シナリオ
• 市況/シェア分析
• M&A（合併・買収）分析

第11章 企業プロファイル

• Thermo Fisher Scientific
  • 会社概要
  • 製品ポートフォリオと説明
  • 財務概要
  • 主な発展状況
• Corning
• Merck KGaA
• PerkinElmer, Inc
• Greiner Bio-One International GmbH
• Agilent Technologies
• BRAND GMBH+CO KG
• Kollodis BioSciences Inc
• DenovoMATRIX
• faCellitate

第12章 付録

Market Overview

The global cell culture protein surface coating market size was valued at US$ 843.4 million in 2022 and is estimated to reach US$ 1,810.5 million by 2030, growing at a CAGR of 10.3% during the forecast period (2023-2030). An increase in the product launches by major key players helps to boost cell culture protein surface coating market growth over the forecast period. For instance, in June 2020, Corning Incorporated launched new products, including Matrigel matrix-3D plates.

Coating as an additional surface treatment stands for all additional modifications made to increase cell adhesion and the standard plasma or corona treatment performed on all cell culture plastic by the manufacturer. Usually, a coating is done with proteins or peptides. The disadvantages of cell culture are: highly skilled personnel, techniques must be performed using strict asepsis techniques because animal cells grow slower than many of the common contaminants (bacteria, viruses, and fungi).

Market Dynamics

Increasing adoption of 3D cell culture will drive the cell culture protein surface coating market growth

The additional dimensionality of 3D cell cultures is the crucial feature leading to the differences in cellular responses. It not only influences the spatial organization of the cell surface receptors engaged in interactions with surrounding cells, but it also induces physical constraints on cells.

These spatial and physical aspects in 3D cultures affect the signal transduction from the outside to the inside of cells and ultimately influence gene expression and cellular behavior. It has been demonstrated that cell responses in 3D cultures are more similar to in vivo behavior compared to 2D cultures.

The risk of microbial contamination and others are factors hindering the market growth

Cell cultures should be constantly monitored to prevent contamination and avoid wastage of protein surface coating of the cell cultures, which can be expensive in nature, thereby impacting the growth of the market.

In addition, tissue composition is variable and heterogeneous. Replicas from the same sample have various constituents. To replicate an experimental result, cell lines must be manipulated many times in serial passages.

For instance, every culture will be different from the original and less uniform in its constitution. The replicas are randomly mixed in each passage to resolve this issue, and the selective pressure of growing conditions tends to produce an optimal prevalent phenotype. These disadvantages will hamper the cell culture protein surface coating market growth.

COVID-19 Impact Analysis

As per the report published by the Journal of Clinical Virology in July 2022, there was a significant positive correlation between the probability of isolating SARS-CoV-2 in culture, fewer days of symptoms, and a lower RT-PCR cycle threshold value.

Hence, the cell culture was used during COVID-19 for proper diagnosis and was expected to drive the growth of the cell culture protein surface coatings market. As viral studies are still ongoing, it is expected to have a significant impact in the coming future.

Russia-Ukraine Conflict Analysis

The conflict between Russia and Ukraine has caused a disruption of the supply chain for some of the equipment used in culture, increasing costs for consumers and making it more difficult for them to access the necessary equipment. These factors have had a significant impact on the cell culture protein surface coating market.

Segment Analysis

The global cell culture protein surface coating market is segmented based on coating type, protein source, and region.

The pre coating segment is expected to hold a dominant position during the forecast period

In coating type segment, the precoating segment accounted for the highest cell culture protein surface coating market size of around 3/5th in 2022. Depending on the quality and quantity control of the plasma treatment surface of the flask, petri dish or microwell plates are activated for adhesion either homogeneously or artefacts, and it may be inserted, as regions like edges are not treated or parts in the middle area or over or under activated.

Another important part of choosing a cell culture consumable supplier is the construction design. Multiwell plates and petri dishes are strongly influenced by adhesion.

Geographical Analysis

North America holds a dominant position in the market

One of the secrets that allow Canada to punch above its weight in the biomanufacturing economy is the tradition of collaboration between academia, industry, non-profits, and government support. In British Columbia, both the University of Victoria and the University of British Columbia have strong undergraduate programs in biomedical engineering that provide an important supply of talent to feed the growing biomanufacturing ecosystems and address challenges in regenerative medicine.

The Canadian government has already invested 1.2 billion dollars into a national biomanufacturing strategy that they continue to support. The Canadian government also supports research and development through its national funding agency - the Natural Sciences and Engineering Research Council.

Competitive Landscape

The major global players include Thermo Fisher Scientific, Corning, Merck, PerkinElmer, Greiner Bio-One International GmbH, Agilent Technologies, BRAND GMBH + CO KG, Kollodis BioSciences, DenovoMATRIX, and faCellitate among others.

Why Purchase the Report?

• To visualize the global cell culture protein surface coating market segmentation based on the type, end user and region, as well as understand key commercial assets and players.
• Identify commercial opportunities by analyzing trends and co-development.
• Excel data sheet with numerous data points of global cell culture protein surface coating market level with all segments.
• PDF report consists of a comprehensive analysis after exhaustive qualitative interviews and an in-depth study.
• Product mapping available as Excel consisting of key products of all the major players.

The global cell culture protein surface coating market report would provide approximately 92 tables, 108 figures and 195 Pages.

Target Audience 2023

• Manufacturers/ Buyers
• Industry Investors/Investment Bankers
• Research Professionals
• Emerging Companies

Table of Contents

1. Methodology and Scope

• 1.1. Research Methodology
• 1.2. Research Objective and Scope of the Report

2. Definition and Overview

3. Executive Summary

• 3.1. Snippet by Coating Type
• 3.2. Snippet by Protein Source
• 3.3. Snippet by Region

4. Dynamics

• 4.1. Impacting Factors
  • 4.1.1. Drivers
    • 4.1.1.1. Increasing the adoption of 3D cell culture will drive the cell culture protein surface coating
  • 4.1.2. Restraints
    • 4.1.2.1. Risk factors such as genetic mutations
  • 4.1.3. Opportunity
  • 4.1.4. Impact Analysis

5. Industry Analysis

• 5.1. Porter's Five Forces Analysis
• 5.2. Supply Chain Analysis
• 5.3. Pricing Analysis
• 5.4. Regulatory Analysis

6. COVID-19 Analysis

• 6.1. Analysis of COVID-19
  • 6.1.1. Before COVID-19 Scenario
  • 6.1.2. Present COVID-19 Scenario
  • 6.1.3. Post COVID-19 or Future Scenario
• 6.2. Pricing Dynamics Amid COVID-19
• 6.3. Demand-Supply Spectrum
• 6.4. Government Initiatives Related to the Market During Pandemic
• 6.5. Manufacturers Strategic Initiatives
• 6.6. Conclusion

7. By Coating Type

• 7.1. Introduction
  • 7.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Coating Type
  • 7.1.2. Market Attractiveness Index, By Coating Type
• 7.2. Precoating*
  • 7.2.1. Multiwall/microwell plates
  • 7.2.2. Introduction
  • 7.2.3. Market Size Analysis and Y-o-Y Growth Analysis (%)
• 7.3. Flasks
• 7.4. Petri dishes
• 7.5. Self-coating

8. By Protein Source

• 8.1. Introduction
  • 8.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Protein Source
  • 8.1.2. Market Attractiveness Index, By Protein Source
• 8.2. Animal-derived*
  • 8.2.1. Introduction
  • 8.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
• 8.3. Synthetic
• 8.4. Human-derived
• 8.5. Plant-derived

9. By Region

• 9.1. Introduction
  • 9.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Region
  • 9.1.2. Market Attractiveness Index, By Region
• 9.2. North America
  • 9.2.1. Introduction
  • 9.2.2. Key Region-Specific Dynamics
  • 9.2.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Coating Type
  • 9.2.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Protein Source
  • 9.2.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
    • 9.2.5.1. The U.S.
    • 9.2.5.2. Canada
    • 9.2.5.3. Mexico
• 9.3. Europe
  • 9.3.1. Introduction
  • 9.3.2. Key Region-Specific Dynamics
  • 9.3.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Coating Type
  • 9.3.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Protein Source
  • 9.3.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
    • 9.3.5.1. Germany
    • 9.3.5.2. The U.K.
    • 9.3.5.3. France
    • 9.3.5.4. Italy
    • 9.3.5.5. Spain
    • 9.3.5.6. Rest of Europe
• 9.4. South America
  • 9.4.1. Introduction
  • 9.4.2. Key Region-Specific Dynamics
  • 9.4.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Coating Type
  • 9.4.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Protein Source
  • 9.4.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
    • 9.4.5.1. Brazil
    • 9.4.5.2. Argentina
    • 9.4.5.3. Rest of South America
• 9.5. Asia-Pacific
  • 9.5.1. Introduction
  • 9.5.2. Key Region-Specific Dynamics
  • 9.5.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Coating Type
  • 9.5.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Protein Source
  • 9.5.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
    • 9.5.5.1. China
    • 9.5.5.2. India
    • 9.5.5.3. Japan
    • 9.5.5.4. Australia
    • 9.5.5.5. Rest of Asia-Pacific
• 9.6. Middle East and Africa
  • 9.6.1. Introduction
  • 9.6.2. Key Region-Specific Dynamics
  • 9.6.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Coating Type
  • 9.6.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Protein Source
  • 9.6.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country

10. Competitive Landscape

• 10.1. Competitive Scenario
• 10.2. Market Positioning/Share Analysis
• 10.3. Mergers and Acquisitions Analysis

11. Company Profiles

• 11.1. Thermo Fisher Scientific*
  • 11.1.1. Company Overview
  • 11.1.2. Product Portfolio and Description
  • 11.1.3. Financial Overview
  • 11.1.4. Key Developments
• 11.2. Corning
• 11.3. Merck KGaA
• 11.4. PerkinElmer, Inc
• 11.5. Greiner Bio-One International GmbH
• 11.6. Agilent Technologies
• 11.7. BRAND GMBH + CO KG
• 11.8. Kollodis BioSciences Inc
• 11.9. DenovoMATRIX
• 11.10. faCellitate

LIST NOT EXHAUSTIVE

12. Appendix

• 12.1. About Us and Services
• 12.2. Contact Us