喘息市場：KOLの洞察

当レポートでは、GSKのデペモキマブ、Tezspireの市場力学、dexpramipexoleのような新規治療など、喘息治療に関するトップKOLの最新の洞察、進化する喘息治療の展望を掘り下げ、最近の臨床試験から得られた主な知見や、新たな治療法が現在の診療に与える影響にハイライトを当てています。

レポートの内容

• 今後3～5年の間に喘息治療に影響を与える大きな変化
• 現在進行中の臨床試験は、Amgen/AstraZenecaの抗TSLPモノクローナル抗体Tezspireの今後の使用にどのような影響を与える可能性があるか
• 抗IL5療法とデュピクセントは重症喘息に対して確立された生物学的製剤であるが、GSKの長時間作用型抗IL5薬デペモキマブはどの程度破壊的な可能性があるのか
• GSKのTrelegy Ellipta、NovartisのEnerzair Breezhaler、ChiesiのTrimbowの3剤併用療法が喘息に果たす役割を専門家はどう見ているのか、また、AstraZenecaのBreztri/Trixeo Aerosphereが役割を果たす可能性はあるのか
• KOLたちは、サノフィの経口BTK阻害剤リルザブルチニブが喘息治療の実践に影響を与える見込みをどのように評価しているのか
• Knopp Biosciencesの経口ドパミン受容体作動薬dexpramipexoleを喘息患者の治療で評価する第III相試験EXHALE-2、-3、-4で、専門家はこの経口ドパミン受容体作動薬の成功の見込みをどのように評価しているか

主要ブランド

Explore the latest insights from top KOLs on asthma therapies, including GSK's depemokimab, Tezspire's market dynamics, and novel treatments like dexpramipexole. This report delves into the evolving landscape of asthma treatment, highlighting key findings from recent clinical trials and the impact of emerging therapies on current practice.

Key Questions Answered:

• What will be the major changes to impact the treatment of asthma over the next three to five years?
• How could ongoing clinical trials impact the future use of Amgen/AstraZeneca's anti-TSLP monoclonal antibody Tezspire?
• The anti-IL5 therapies and Dupixent are well-established biologics for severe asthma, but just how disruptive could GSK's long-acting anti-IL5 agent depemokimab be?
• How do experts view the role of fixed-dose triple-combination therapies (GSK's Trelegy Ellipta, Novartis' Enerzair Breezhaler and Chiesi's Trimbow) in asthma, and could AstraZeneca's Breztri/Trixeo Aerosphere find a role?
• How do the KOLs assess the prospects for Sanofi's oral BTK inhibitor rilzabrutinib to impact asthma treatment practice?
• With the Phase III EXHALE-2, -3 and -4 trials evaluating Knopp Biosciences' dexpramipexole in the treatment of patients with asthma, how do experts weigh up this oral dopamine receptor agonist's prospects for success?

Key Brands:

Partial List of Participating Experts:

• Professor of Pediatrics, Allergy/Immunology/Pulmonary Medicine, Scientific Director of the Center for Clinical and Translational Research, Vanderbilt University Medical Center, USA
• Professor of Medicine (Pulmonary, Critical Care and Sleep Medicine), Yale School of Medicine, USA
• Clinical Professor of Medicine, University of Medicine and Dentistry of New Jersey - Rutgers, Director of Clinical Research at Pulmonary and Allergy Associates, USA
• Professor of Thoracic Medicine and Head of Respiratory Medicine at the National Heart and Lung Institute and Honorary Consultant Physician at Royal Brompton Hospital, Senior Research Investigator at Imperial College, UK
• Head of Pulmonology, Consultant and Professor of Respiratory Medicine at Arnaud de Villeneuve Hospital/University of Montpellier, France
• Head of Department of Allergy, La Paz University Hospital, IdiPAZ, CIBER of Respiratory Diseases (CIBERES), Universidad Autenoma de Madrid, Spain

Methodology

Therapy Trend reports are developed through in-depth interviews with the world's foremost Key Opinion Leaders (KOLs) on the current and future treatment landscapes in major disease areas. KOLs are carefully selected based on strict screening criteria, including their global reputation, clinical expertise, and influence within their therapeutic area. Each interview is guided by a meticulously crafted discussion guide. These guides are developed in collaboration with KOLs and peer-reviewed by industry experts to ensure that the questions are comprehensive and pertinent to current market dynamics. Through continuous market monitoring over a 12-month period following the publication of each report, we provide timely updates from KOLs on key news events, market shifts, and clinical developments.

What makes our reports different?

FirstWord Reports, a trusted industry leader with an exclusive focus on the pharmaceutical sector, delivers in-depth, actionable insights for biopharma professionals and decision-makers. Our deep industry knowledge enables us to provide relevant and valuable insights that help you identify emerging trends and navigate complex challenges effectively. Backed by extensive research and independent, impartial insights from leading experts and KOLs, our reports deliver the accuracy and reliability you need. With exclusive access to interviews and data unavailable elsewhere, along with ongoing market monitoring, we give you a comprehensive view of market dynamics. Covering over 40 dynamic disease areas and providing physician intelligence, including KOL insights and quantitative physician surveys, as well as industry expert views on issues in medical affairs, digital health, sales & marketing, market access, and other areas, our reports empower you to make smarter, data-driven decisions and maintain a competitive edge in a fast-moving industry.