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市場調査レポート
商品コード
1656917
先端医療医薬品(ATMP)の世界市場 - 市場考察、競合情勢、市場予測(2032年)Advanced Therapy Medicinal Products - Market Insights, Competitive Landscape, and Market Forecast - 2032 |
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先端医療医薬品(ATMP)の世界市場 - 市場考察、競合情勢、市場予測(2032年) |
出版日: 2025年01月01日
発行: DelveInsight
ページ情報: 英文 150 Pages
納期: 2~10営業日
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世界の先端医療医薬品(ATMP)の市場規模は、2024年に307億7,872万米ドルであり、2025年~2032年の予測期間にCAGRで14.17%の成長が見込まれます。市場の成長は、主に慢性疾患の有病率の増加によってもたらされます。遺伝性疾患やがん患者の増加、研究開発活動の活発化、主要企業間の提携は、2025年~2032年の予測期間に先端医療医薬品(ATMP)市場のプラス成長に寄与する主な要因です。
先端医療医薬品(ATMP)の市場力学
米国疾病予防管理センター(CDC)が2024年2月に発表したデータによると、米国では2024年時点で推定1億2,900万人が心臓病、がん、糖尿病、肥満、高血圧など少なくとも1つの主要な慢性疾患に罹患しています。
がんは世界中の人々に影響を及ぼしている主な慢性疾患です。International Agency for Research on Cancerが2020年12月に実施した調査によると、2020年に世界中で新たに1,930万人のがん患者が発生すると推定されています。細胞療法は、がん細胞を効果的に破壊するために身体の免疫細胞を使用するがん免疫療法に使用されます。そのため、細胞療法や遺伝子治療の需要を生み出しているがんなどの慢性疾患の有病率の上昇は、市場の成長を促進すると予測されています。
2023年2月に発表されたWorld Economic Forumのレポートによると、2021年に世界中で約4億7,500万人が希少遺伝性疾患を抱えて生活しています。今後5年以内に、約1,520万人が希少疾患の特定を目的とした臨床ゲノム検査を受けると予測されています。遺伝子治療は、疾患を治したり、疾患に対抗する体の能力を高めたりするために、異常な遺伝子を修正したり、健康な遺伝子に置き換えたりするために開発されます。したがって、遺伝性疾患の患者数の増加が市場成長を促進すると予測されます。
市場の主要企業は、がんや神経変性疾患などの慢性疾患の治療に向け、精密細胞・遺伝子治療開発の研究パートナーシップを確立しています。例えば2021年4月、Spark Therapeuticsは、遺伝子治療研究を強化するため、Senti Biosciencesとの研究協力を発表しました。この共同研究は、Senti Bioの先進の遺伝子回路技術プラットフォームとハイスループット合成プロモーター設計の専門知識を、Spark Therapeuticsの中枢神経系、眼、肝臓を標的とした治験中の遺伝子治療薬に統合するものです。先進の遺伝子治療を開発するためのこのような研究協力は、開発を後押しすると予測されます。
しかし、細胞・遺伝子治療の高いコストや、先端医療医薬品(ATMP)に関連する安全性への懸念などが、先端医療医薬品(ATMP)市場の成長を妨げる可能性のある主な抑制要因となっています。
先端医療医薬品(ATMP)市場のセグメント分析
製品タイプ別では、疾患治療を一変させる可能性があることから、細胞治療薬カテゴリが2024年の先端医療医薬品(ATMP)市場において最大の市場シェアを占めると推定されます。細胞療法は、生存可能で機能的な細胞を患者の体内に導入し、損傷した組織を強化または置換する革新的な医療アプローチであり、特に細胞の機能不全や喪失が特定の疾患の進行に重要な役割を果たしている場合に有益です。細胞療法は成功を収めており、主要企業はこの分野でがんなどのさまざまな疾患の治療に向けた次世代プログラム細胞療法の開発に取り組んでいます。例えば2024年2月、BioNTechは細胞療法の開発と商業化に向けたAutolus Therapeuticsとの提携を発表しました。この戦略的提携は、複数のがんを適応症とする両社の自己CAR-Tプログラムを推進することを目的としています。
CAR-T細胞療法は、患者のT細胞を抽出、遺伝子改変、活性化、拡大、精製し、患者の体内に再導入する個別化アプローチの代表例です。このような利点が、この分野の主要企業による研究活動を後押ししています。2024年3月、Bristol-Myers Squibb Companyは、再発または難治性の慢性リンパ性白血病(CLL)または小リンパ球性リンパ腫(SLL)の成人患者に対する治療薬として、CD19指向性CAR-T細胞治療薬であるBreyanzi(R)(lisocabtagene maraleucel、liso-cel)が米国食品医薬品局(FDA)から早期承認されたと発表しました。
当レポートでは、世界の先端医療医薬品(ATMP)市場について調査分析し、市場規模と予測、過去3年の製品/技術開発、市場の主要企業、利用可能な機会などの情報を提供しています。
Advanced Therapy Medicinal Products Market by Type (Gene-Therapy Medicines, Cell Therapy Medicines, Tissue Engineered Products, Combined ATMPs), Indication (Oncology, Cardiology, Neurology, Genetic Disorders, Infectious Diseases, Metabolic Disease, and Others), and Geography (North America, Europe, Asia-Pacific, and Rest of the World) is expected to grow at a steady CAGR forecast till 2032 owing to the growing prevalence of chronic disease and rising number of genetic disease and cancer cases
The advanced therapy medicinal products (ATMP) market was valued at USD 30,778.72 million in 2024, growing at a CAGR of 14.17% during the forecast period from 2025 to 2032. The growth of the advanced therapy medicinal products market is mainly driven by the growing prevalence of chronic diseases. The rising number of genetic diseases, and cancer cases, increasing R&D activities, and partnerships among key players are key factors responsible for contributing to the positive growth of the advanced therapy medicinal products market during the forecast period from 2025 to 2032.
Advanced Therapy Medicinal Products Market Dynamics:
According to the data published by the Centers for Disease Control and Prevention (CDC) in February 2024, an estimated 129 million people were suffering from at least 1 major chronic disease such as heart disease, cancer, diabetes, obesity, and hypertension in the United States as of 2024.
Cancer is a major chronic disease affecting people around the world. The study conducted by the International Agency for Research on Cancer in December 2020, mentioned that an estimated 19.3 million new cancer cases were reported in 2020 across the globe. Cell therapy is used in cancer immunotherapy which uses the immune cells of the body to destroy cancer cells effectively. Thereby, the rising prevalence of chronic diseases such as cancer which is creating the demand for cell and gene therapy is expected to drive the market growth.
A report by the World Economic Forum published in February 2023, stated that approximately 475 million individuals were living with genetic rare conditions in 2021 across the globe. Within the upcoming five years, it was anticipated that around 15.2 million people were expected to undergo clinical genomic testing specifically aimed at identifying rare conditions. Gene therapy is developed to correct or replace abnormal genes with healthy ones to cure diseases or enhance the body's ability to combat them. Thus, the rising number of genetic disease cases is expected to propel the market growth.
Key players in the market are establishing research partnerships for the development of precision cell and gene therapies for the treatment of chronic diseases such as cancer and neurodegenerative diseases. For instance, in April 2021, Spark Therapeutics announced a research collaboration with Senti Biosciences to enhance its gene therapy research. The collaboration integrates Senti Bio's advanced gene circuit technology platform and expertise in high-throughput synthetic promoter design with Spark Therapeutics' investigational gene therapies targeting the central nervous system, eye, or liver. Such research collaborations to develop advanced gene therapies are expected to boost market expansion.
However, the high cost of cell and gene therapies, and the safety concerns associated with advanced therapy medicinal products, among others are some of the key constraints that may hinder the growth of the advanced therapy medicinal products market.
Advanced Therapy Medicinal Products Market Segment Analysis:
Advanced Therapy Medicinal Products Market by Type (Gene-Therapy Medicines, Cell Therapy Medicines, Tissue Engineered Products, Combined ATMPs), Indication (Oncology, Cardiology, Neurology, Genetic Disorders, Infectious Diseases, Metabolic Disease, and Others), and Geography (North America, Europe, Asia-Pacific, and Rest of the World)
In the type segment, the cell therapy medicines category is estimated to account for the largest market share in the advanced therapy medicinal products market in 2024 due to the potential of cell therapies to transform disease treatment. Cell therapy is an innovative medical approach involving the introduction of viable and functional cells into a patient's body to enhance or replace damaged tissues, particularly beneficial when cell dysfunction or loss plays a crucial role in the progression of a specific disease. Cell therapies have shown success due to which key players are working in this area to develop next-generation programmed cell therapies for the treatment of various diseases such as cancer. For instance, in February 2024, BioNTech announced its partnership with Autolus Therapeutics to develop and commercialization of cell therapies. This strategic collaboration aimed at advancing both companies' autologous CAR-T programs for the treatment of multiple cancer indications.
CAR-T cell therapy exemplifies this personalized approach where a patient's T cells are extracted, genetically modified, activated, expanded, purified, and then reintroduced into the patient's body. Such advantages have boosted the research activities made by key players in this area. In March 2024, Bristol-Myers Squibb Company announced that the U.S. Food and Drug Administration (FDA) has granted accelerated approval for Breyanzi(R) (lisocabtagene maraleucel; liso-cel), a CD19-directed CAR T cell therapy, for treating adult patients with relapsed or refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).
Further, cell therapy leverages the body's natural systems such as the cellular immune system and the capacity to repair or replace faulty genes making them preferred choices for personalized medicine. Therefore, the growing use and development of cell therapies, including stem cell therapy, CAR-T cell therapy, and tissue engineering contribute to the growth of the segment, thereby driving the growth of the advanced therapy medicinal products market during the forecast period.
North America Is Expected To Dominate The Overall Advanced Therapy Medicinal Products Market:
North America is expected to account for the largest market share of the advanced therapy medicinal products market in 2024. This can be attributed to the rising number of cancer cases and the rise in the R&D activities by key players in the region, thus driving the growth of the advanced therapy medicinal products market in North America.
According to the American Cancer Society's Cancer Facts & Figures published in 2024, nearly 2 million new cancer cases were expected to be diagnosed in the United States in 2024, up from 1.9 million in 2023. Cell therapy genetically modifies a patient's cells to express a particular receptor that targets cancer cells. These altered cells are then injected into the patient's body, where they can identify tumor antigens and destroy cancer cells expressing the targeted antigen. Therefore, the rising cancer cases that create demand for advanced therapies will drive market growth.
The data published by the National Cancer Institute in May 2024 indicated that there were an estimated 18.1 million cancer patients in the United States in 2022 and this number of cancer patients is expected to increase reaching 22.5 million by 2032 and 26 million by 2040.
Rising R&D activities of key players in the region to innovative advanced therapy medicinal products for the treatment of chronic diseases are contributing to the positive growth of the market. For instance, in February 2022, Janssen Pharmaceuticals announced that the U.S. Food and Drug Administration (FDA) approved CARVYKTI (ciltacabtagene autoleucel; cilta-cel) for the treatment of patients with relapsed or refractory multiple myeloma (RRMM). CARVYKTI(TM) is a type of CAR-T therapy that utilizes two single-domain antibodies targeting B-cell maturation antigen (BCMA). Therefore, the rising number of cancer cases and surge in R&D activities by key players in the region is expected to propel the growth of North America advanced therapy medicinal products market.
Advanced Therapy Medicinal Products Market Key Players:
Some of the key market players operating in the advanced therapy medicinal products market include Pfizer Inc., Novartis AG, Gilead Sciences, Inc., Kolon TissueGene, Inc., Bluebird Bio, Inc., F. Hoffmann-La Roche Ltd, Bristol-Myers Squibb Company, Organogenesis Inc., BioNTech, Regeneron Pharmaceuticals Inc., ALLOGENE THERAPEUTICS, CRISPR Therapeutics, Autolus Therapeutics, Anixa Biosciences, Inc., Amgen Inc., Intellia Therapeutics, Inc., Adaptimmune, Voyager Therapeutics Inc., Sangamo Therapeutics, Inc., Biogen, and others.
Recent Developmental Activities in the Advanced Therapy Medicinal Products Market:
Key Takeaways from the Advanced Therapy Medicinal Products Market Report Study
Target Audience who can be benefited from this Advanced Therapy Medicinal Products Market Report Study
Frequently Asked Questions for the Advanced Therapy Medicinal Products Market: