エフルキシフェルミン市場：市場規模、予測、新たな洞察-2032年

エフルキシフェルミン（EFX）（旧AKR-001）は、アケロのNASHに対する主力製品候補です。EFXは、細胞ストレスを緩和し、全身の代謝を調節する内因性ホルモンであるFGF21のバランスのとれた生物学的活性プロファイルを模倣するように設計された、分化型Fc-FGF21融合タンパク質です。EFXは、便利な週1回のSC投与が可能なように設計されています。観察された効果の一貫性と大きさから、EFXは、承認されればNASH治療薬としてクラス最高の薬剤となる可能性があります。

EFXは現在、生検でNASHが確認された患者さんを対象とした2つの臨床第IIb相試験（F2-F3線維化を有する肝硬変前患者さんを対象としたHARMONY試験およびF4線維化を有する肝硬変患者さんを対象としたSYMMETRY試験）で評価されています。NASH（F4）による代償性肝硬変患者を対象とした本試験の結果は、2023年第4四半期に出る予定です。

当レポートでは、主要7ヶ国におけるエフルキシフェルミン市場について調査し、市場の概要とともに、競合情勢、2032年までの市場規模予測、および国別市場分析などを提供しています。

目次

第1章 レポートのイントロダクション

第2章 非アルコール性脂肪肝炎（NASH）におけるエフルキシフェルミンの概要

• 製品詳細
• 臨床開発
• その他の開発活動
• 製品プロファイル

第3章 競合情勢（上市済み治療法）

第4章 競合情勢（後期段階の新興治療法）

第5章 エフルキシフェルミン市場評価

• 非アルコール性脂肪肝炎（NASH）におけるエフルキシフェルミンの市場展望
• 主要7ヶ国分析
• 国別市場分析
  • 米国
  • ドイツ
  • 英国

第6章 SWOT分析

第7章 アナリストの見解

第8章 付録

第9章 DelveInsightのサービス内容

第10章 免責事項

第11章 DelveInsightについて

第12章 レポート購入オプション

List of Tables

• Table 1: Efruxifermin, Clinical Trial Description, 2023
• Table 2: Efruxifermin, General Description
• Table 3: Competitive Landscape (Marketed Therapies)
• Table 4: Competitive Landscape (Emerging Therapies)
• Table 5: Efruxifermin Market Size in the 7MM, in USD million (2019-2032)
• Table 6: Efruxifermin Market Size in the US, in USD million (2019-2032)
• Table 7: Efruxifermin Market Size in Germany, in USD million (2019-2032)
• Table 8: Efruxifermin Market Size in France, in USD million (2019-2032)
• Table 9: Efruxifermin Market Size in Italy, in USD million (2019-2032)
• Table 10: Efruxifermin Market Size in Spain, in USD million (2019-2032)
• Table 11: Efruxifermin Market Size in the UK, in USD million (2019-2032)
• Table 12: Efruxifermin Market Size in Japan, in USD million (2019-2032)

List of Figures

• Figure 1: Efruxifermin Market Size in the 7MM, USD million (2019-2032)
• Figure 2: Efruxifermin Market Size in the United States, USD million (2019-2032)
• Figure 3: Efruxifermin Market Size in Germany, USD million (2019-2032)
• Figure 4: Efruxifermin Market Size in France, USD million (2019-2032)
• Figure 5: Efruxifermin Market Size in Italy, USD million (2019-2032)
• Figure 6: Efruxifermin Market Size in Spain, USD million (2019-2032)
• Figure 7: Efruxifermin Market Size in the United Kingdom, USD million (2019-2032)
• Figure 8: Efruxifermin Market Size in Japan, USD million (2019-2032)

"Efruxifermin Market Size, Forecast, and Emerging Insight - 2032" report provides comprehensive insights about Efruxifermin for Non-alcoholic Steatohepatitis (NASH) in the seven major markets. A detailed picture of the Efruxifermin for NASH in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the Efruxifermin for NASH. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the Efruxifermin market forecast analysis for NASH in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in NASH.

Drug Summary:

Efruxifermin (EFX), formerly AKR-001, is Akero's lead product candidate for NASH. It is a differentiated Fc-FGF21 fusion protein engineered to mimic the balanced biological activity profile of native FGF21, an endogenous hormone that alleviates cellular stress and regulates metabolism throughout the body. EFX is designed to offer convenient once-weekly SC dosing. The consistency and magnitude of observed effects position EFX to be a potentially best-in-class medicine, if approved, for treating NASH.

EFX is currently being evaluated in two Phase IIb clinical trials in patients with biopsy-confirmed NASH: the HARMONY study in pre-cirrhotic patients with F2-F3 fibrosis and the SYMMETRY study in cirrhotic patients with compensated F4 fibrosis. Results of the main study in patients with compensated cirrhosis due to NASH (F4) expected in fourth quarter of 2023.

Scope of the Report:

The report provides insights into:

• A comprehensive product overview including the Efruxifermin description, mechanism of action, dosage and administration, research and development activities in Non-alcoholic Steatohepatitis (NASH).
• Elaborated details on Efruxifermin regulatory milestones and other development activities have been provided in this report.
• The report also highlights the Efruxifermin research and development activities in NASH across the United States, Europe, and Japan.
• The report also covers the patents information with expiry timeline around Efruxifermin.
• The report contains forecasted sales of Efruxifermin for NASH till 2032.
• Comprehensive coverage of the late-stage emerging therapies for NASH.
• The report also features the SWOT analysis with analyst views for Efruxifermin in NASH.

Methodology:

The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.

Efruxifermin Analytical Perspective by DelveInsight

• In-depth Efruxifermin Market Assessment

This report provides a detailed market assessment of Efruxifermin for Non-alcoholic Steatohepatitis (NASH) in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2027 to 2032.

• Efruxifermin Clinical Assessment

The report provides the clinical trials information of Efruxifermin for Non-alcoholic Steatohepatitis (NASH) covering trial interventions, trial conditions, trial status, start and completion dates.

Report Highlights:

• In the coming years, the market scenario for Non-alcoholic Steatohepatitis (NASH) is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
• The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence Efruxifermin dominance.
• Other emerging products for NASH are expected to give tough market competition to Efruxifermin and launch of late-stage emerging therapies in the near future will significantly impact the market.
• A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of Efruxifermin in NASH.
• Our in-depth analysis of the forecasted sales data of Efruxifermin from 2027 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the Efruxifermin in NASH.

Key Questions:

• What is the product type, route of administration and mechanism of action of Efruxifermin?
• What is the clinical trial status of the study related to Efruxifermin in Non-alcoholic Steatohepatitis (NASH) and study completion date?
• What are the key collaborations, mergers and acquisitions, licensing and other activities related to the Efruxifermin development?
• What are the key designations that have been granted to Efruxifermin for NASH?
• What is the forecasted market scenario of Efruxifermin for NASH?
• What are the forecasted sales of Efruxifermin in the seven major countries, including the United States, Europe (Germany, France, Italy, Spain) and the United Kingdom, and Japan?
• What are the other emerging products available and how are these giving competition to Efruxifermin for NASH?
• Which are the late-stage emerging therapies under development for the treatment of NASH?

Table of Contents

1. Report Introduction

2. Efruxifermin Overview in Non-alcoholic Steatohepatitis (NASH)

• 2.1. Product Detail
• 2.2. Clinical Development
  • 2.2.1. Clinical studies
  • 2.2.2. Clinical trials information
  • 2.2.3. Safety and efficacy
• 2.3. Other Developmental Activities
• 2.4. Product Profile

3. Competitive Landscape (Marketed Therapies)

4. Competitive Landscape (Late-stage Emerging Therapies)

5. Efruxifermin Market Assessment

• 5.1. Market Outlook of Efruxifermin in Non-alcoholic Steatohepatitis (NASH)
• 5.2. 7MM Analysis
  • 5.2.1. Market Size of Efruxifermin in the 7MM for Non-alcoholic Steatohepatitis (NASH)
• 5.3. Country-wise Market Analysis
  • 5.3.1. Market Size of Efruxifermin in the United States for Non-alcoholic Steatohepatitis (NASH)
  • 5.3.2. Market Size of Efruxifermin in Germany for Non-alcoholic Steatohepatitis (NASH)
  • 5.3.3. Market Size of Efruxifermin in France for Non-alcoholic Steatohepatitis (NASH)
  • 5.3.4. Market Size of Efruxifermin in Italy for Non-alcoholic Steatohepatitis (NASH)
  • 5.3.5. Market Size of Efruxifermin in Spain for Non-alcoholic Steatohepatitis (NASH)
  • 5.3.6. Market Size of Efruxifermin in the United Kingdom for Non-alcoholic Steatohepatitis (NASH)
  • 5.3.7. Market Size of Efruxifermin in Japan for Non-alcoholic Steatohepatitis (NASH)

6. SWOT Analysis

7. Analysts' Views

8. Appendix

• 8.1. Bibliography
• 8.2. Report Methodology

9. DelveInsight Capabilities

10. Disclaimer

11. About DelveInsight

12. Report Purchase Options