VEMLIDY市場：市場規模、予測、市場洞察-2032年

VEMLIDYはHBVヌクレオシド類似体逆転写酵素阻害剤であり、成人および12歳以上の代償性肝疾患を有する小児患者における慢性B型肝炎ウイルス感染の治療に適応があります。

VEMLIDYは新規のテノホビルの標的プロドラッグで、GileadのVIREAD（テノホビルジソプロキシルフマル酸塩、TDF）300mgと同様の抗ウイルス効果を示し、その用量はGileadのVIREAD（テノホビルジソプロキシルフマル酸塩、TDF）300mgの10分の1以下です。製品ラベルには、乳酸アシドーシス/脂肪症を伴う重篤な肝腫大、および治療後のB型肝炎の重篤な急性増悪のリスクに関する枠付き警告が記載されています。

今後数年間で、慢性B型肝炎の市場シナリオは、世界中の広範な調査と医療支出の増加により変化します。各社は、病状を治療/改善するための新たなアプローチに焦点を当てた治療法を開発し、課題を評価し、VEMLIDYの優位性に影響を与える可能性のある機会を模索しています。慢性B型肝炎を対象とした他の新興製品がVEMLIDYと厳しい市場競争を繰り広げることが予想され、近い将来、後発の新興治療薬が上市されれば、市場に大きな影響を与えるとみられています。

当レポートでは、主要7ヶ国および中国における慢性B型肝炎治療薬のVEMLIDY市場について調査し、市場の概要とともに、競合情勢、2032年までの市場規模予測、および国別市場分析などを提供しています。

目次

第1章 レポートのイントロダクション

第2章 慢性B型肝炎におけるVEMLIDYの概要

• 製品の詳細
• 臨床開発
  • 臨床研究
  • 臨床試験情報
  • 安全性と有効性
• 規制のマイルストーン
• その他の開発活動
• 製品プロファイル

第3章 競合情勢（上市済み治療法）

第4章 競合情勢（後期段階の新興治療法）

第5章 VEMLIDY市場評価

• 慢性B型肝炎におけるVEMLIDYの市場見通し
• 主要7ヶ国と中国の分析
  • 主要7ヶ国および中国の慢性B型肝炎治療薬VEMLIDYの市場規模
• 国別市場分析
  • 米国
  • ドイツ
  • 英国
  • 中国

第6章 SWOT分析

第7章 アナリストの見解

第8章 付録

第9章 DelveInsightのサービス内容

第10章 免責事項

第11章 DelveInsightについて

第12章 レポート購入オプション

List of Tables

• Table 1: VEMLIDY, Clinical Trial Description, 2023
• Table 2: VEMLIDY, General Description
• Table 3: Competitive Landscape (Marketed Therapies)
• Table 4: Competitive Landscape (Late-stage Emerging Therapies)
• Table 5: VEMLIDY Market Size in the 7MM and China, in USD million (2019-2032)
• Table 6: VEMLIDY Market Size in the US, in USD million (2019-2032)
• Table 7: VEMLIDY Market Size in Germany, in USD million (2019-2032)
• Table 8: VEMLIDY Market Size in France, in USD million (2019-2032)
• Table 9: VEMLIDY Market Size in Italy, in USD million (2019-2032)
• Table 10: VEMLIDY Market Size in Spain, in USD million (2019-2032)
• Table 11: VEMLIDY Market Size in the UK, in USD million (2019-2032)
• Table 12: VEMLIDY Market Size in Japan, in USD million (2019-2032)
• Table 13: VEMLIDY Market Size in China, in USD million (2019-2032)

List of Figures

• Figure 1: VEMLIDY Market Size in the 7MM and China, USD million (2019-2032)
• Figure 2: VEMLIDY Market Size in the United States, USD million (2019-2032)
• Figure 3: VEMLIDY Market Size in Germany, USD million (2019-2032)
• Figure 4: VEMLIDY Market Size in France, USD million (2019-2032)
• Figure 5: VEMLIDY Market Size in Italy, USD million (2019-2032)
• Figure 6: VEMLIDY Market Size in Spain, USD million (2019-2032)
• Figure 7: VEMLIDY Market Size in the United Kingdom, USD million (2019-2032)
• Figure 8: VEMLIDY Market Size in Japan, USD million (2019-2032)
• Figure 9: VEMLIDY Market Size in China, USD million (2019-2032)

"VEMLIDY Market Size, Forecast, and Market Insight - 2032" report provides comprehensive insights about VEMLIDY for chronic hepatitis B in the seven major markets and China. A detailed picture of the VEMLIDY for chronic hepatitis B in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, Japan, and China for the study period 2019 -2032 is provided in this report along with a detailed description of the VEMLIDY for chronic hepatitis B. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the VEMLIDY market forecast analysis for chronic hepatitis B in the 7MM and China, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in chronic hepatitis B.

Drug Summary:

VEMLIDY is a HBV nucleoside analog reverse transcriptase inhibitor and is indicated for treating chronic hepatitis B virus infection in adults and pediatric patients 12 years and older with compensated liver disease.

VEMLIDY is a novel, targeted prodrug of tenofovir that has demonstrated antiviral efficacy similar to and at a dose less than one-tenth that of Gilead's VIREAD (tenofovir disoproxil fumarate, TDF) 300 mg. It has a boxed warning on its product label regarding the risks of lactic acidosis/severe hepatomegaly with steatosis and post-treatment severe acute exacerbation of hepatitis B.

• Dosage and administration

The recommended dosage of VEMLIDY in adults and pediatric patients aged 12 and older is one 25 mg tablet taken orally once daily with food.

• Mechanism of action

Tenofovir alafenamide is an antiviral drug against the hepatitis B virus; it is a phosphonamidate prodrug of tenofovir (2'-deoxyadenosine monophosphate analog). Tenofovir alafenamide is a lipophilic cell-permeate compound that enters primary hepatocytes by passive diffusion and hepatic uptake transporters OATP1B1 and OATP1B3. It is then converted to tenofovir through hydrolysis, primarily by carboxylesterase 1 (CES1) in primary hepatocytes. Intracellular tenofovir is subsequently phosphorylated by cellular kinases to the pharmacologically active metabolite tenofovir diphosphate. Tenofovir diphosphate inhibits HBV replication through incorporation into viral DNA by the HBV reverse transcriptase, which results in DNA chain termination.

Scope of the Report:

The report provides insights into:

• A comprehensive product overview including the VEMLIDY description, mechanism of action, dosage and administration, research and development activities in chronic hepatitis B.
• Elaborated details on VEMLIDY regulatory milestones and other development activities have been provided in this report.
• The report also highlights the VEMLIDY research and development activities in chronic hepatitis B across the United States, Europe, Japan, and China.
• The report also covers the patents information with expiry timeline around VEMLIDY.
• The report contains forecasted sales of VEMLIDY for chronic hepatitis B till 2032.
• Comprehensive coverage of the late-stage emerging therapies for chronic hepatitis B.
• The report also features the SWOT analysis with analyst views for VEMLIDY in chronic hepatitis B.

Methodology:

The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.

VEMLIDY Analytical Perspective by DelveInsight

• In-depth VEMLIDY Market Assessment

This report provides a detailed market assessment of VEMLIDY for chronic hepatitis B in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, Japan, and China. This segment of the report provides forecasted sales data from 2024 to 2032.

• VEMLIDY Clinical Assessment

The report provides the clinical trials information of VEMLIDY for chronic hepatitis B covering trial interventions, trial conditions, trial status, start and completion dates.

Report Highlights:

• In the coming years, the market scenario for chronic hepatitis B is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
• The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence VEMLIDY dominance.
• Other emerging products for chronic hepatitis B are expected to give tough market competition to VEMLIDY and launch of late-stage emerging therapies in the near future will significantly impact the market.
• A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of VEMLIDY in chronic hepatitis B.
• Our in-depth analysis of the forecasted sales data of VEMLIDY from 2024 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the VEMLIDY in chronic hepatitis B.

Key Questions:

• What is the product type, route of administration and mechanism of action of VEMLIDY?
• What is the clinical trial status of the study related to VEMLIDY in chronic hepatitis B and study completion date?
• What are the key collaborations, mergers and acquisitions, licensing and other activities related to the VEMLIDY development?
• What are the key designations that have been granted to VEMLIDY for chronic hepatitis B?
• What is the forecasted market scenario of VEMLIDY for chronic hepatitis B?
• What are the forecasted sales of VEMLIDY in the seven major countries, including the United States, Europe (Germany, France, Italy, Spain, and the United Kingdom), Japan, and China?
• What are the other emerging products available and how are these giving competition to VEMLIDY for chronic hepatitis B?
• Which are the late-stage emerging therapies under development for the treatment of chronic hepatitis B?

Table of Contents

1. Report Introduction

2. VEMLIDY Overview in Chronic hepatitis B

• 2.1. Product Detail
• 2.2. Clinical Development
  • 2.2.1. Clinical studies
  • 2.2.2. Clinical trials information
  • 2.2.3. Safety and efficacy
• 2.3. Regulatory Milestones
• 2.4. Other Developmental Activities
• 2.5. Product Profile

3. Competitive Landscape (Marketed Therapies)

4. Competitive Landscape (Late-stage Emerging Therapies)

5. VEMLIDY Market Assessment

• 5.1. Market Outlook of VEMLIDY in Chronic hepatitis B
• 5.2. 7MM and China Analysis
  • 5.2.1. Market Size of VEMLIDY in the 7MM and China for Chronic hepatitis B
• 5.3. Country-wise Market Analysis
  • 5.3.1. Market Size of VEMLIDY in the United States for Chronic hepatitis B
  • 5.3.2. Market Size of VEMLIDY in Germany for Chronic hepatitis B
  • 5.3.3. Market Size of VEMLIDY in France for Chronic hepatitis B
  • 5.3.4. Market Size of VEMLIDY in Italy for Chronic hepatitis B
  • 5.3.5. Market Size of VEMLIDY in Spain for Chronic hepatitis B
  • 5.3.6. Market Size of VEMLIDY in the United Kingdom for Chronic hepatitis B
  • 5.3.7. Market Size of VEMLIDY in Japan for Chronic hepatitis B
  • 5.3.8. Market Size of VEMLIDY in China for Chronic hepatitis B

6. SWOT Analysis

7. Analysts' Views

8. Appendix

• 8.1. Bibliography
• 8.2. Report Methodology

9. DelveInsight Capabilities

10. Disclaimer

11. About DelveInsight

12. Report Purchase Options