Pelacarsenの市場規模、予測、新薬の考察（2032年）

薬剤のサマリー

Pelacarsen（TQJ230）は、IONIS-APO(a)-LRx、AKCEA-APO(a)-LRxとしても知られる試験中のアンチセンス医薬で、肝臓のアポリポタンパク（a）を減少させるよう設計されています。Lp(a)の上昇は、冠動脈疾患、心臓発作、脳卒中、末梢動脈疾患などの独立した遺伝的原因として認識されています。現在のところ、Lp(a)の上昇を有意に低下させる有効な薬物療法はありません。Lp(a)値は出生時に決定され、食事や運動などの生活習慣の改善はLp(a)値に影響を与えません。LDL-Cをコントロールできる患者であっても、Lp(a)値が高ければ心血管イベントのリスクは高いままです。

Pelacarsenは、Lp(a)値が高いためにCVDのリスクが高い患者を対象として開発されています。Pelacarsenは、Lp(a)の産生を選択的かつ強力に阻害するように設計された、臨床開発中の最初の薬剤です。

同社の2022年第3四半期の投資家向けプレゼンテーションによると、Novartisは2025年にPelacarsenの申請とデータ発表を予定しています。

当レポートでは、主要7市場（米国・ドイツ・フランス・イタリア・スペイン・英国・日本）における心筋梗塞向けPelacarsenについて調査分析し、作用機序、用法と用量、研究開発活動についての考察、収益の予測などを提供しています。

目次

第1章 レポートのイントロダクション

第2章 心筋梗塞におけるPelacarsenの概要

• 製品の詳細
• 臨床開発
  • 臨床研究
  • 臨床試験情報
  • 安全性と有効性
• その他の開発活動
• 製品プロファイル

第3章 競合情勢（上市済みの治療法）

第4章 競合情勢（後期の新治療法）

第5章 Pelacarsen市場の評価

• 心筋梗塞におけるPelacarsenの市場見通し
• 主要7市場の分析
  • 主要7市場の心筋梗塞向けPelacarsenの市場規模
• 市場の分析：国別
  • 米国の心筋梗塞向けPelacarsenの市場規模
  • ドイツの心筋梗塞向けPelacarsenの市場規模
  • 英国の心筋梗塞向けPelacarsenの市場規模

第6章 SWOT分析

第7章 アナリストの見解

第8章 付録

第9章 DelveInsightのサービス内容

第10章 免責事項

第11章 DelveInsightについて

第12章 レポート購入オプション

List of Tables

• Table 1: Pelacarsen, Clinical Trial Description, 2023
• Table 2: Pelacarsen, General Description
• Table 3: Competitive Landscape (Marketed Therapies)
• Table 4: Competitive Landscape (Late-stage Emerging Therapies)
• Table 5: Pelacarsen Market Size in the 7MM, in USD million (2019-2032)
• Table 6: Pelacarsen Market Size in the US, in USD million (2019-2032)
• Table 7: Pelacarsen Market Size in Germany, in USD million (2019-2032)
• Table 8: Pelacarsen Market Size in France, in USD million (2019-2032)
• Table 9: Pelacarsen Market Size in Italy, in USD million (2019-2032)
• Table 10: Pelacarsen Market Size in Spain, in USD million (2019-2032)
• Table 11: Pelacarsen Market Size in the UK, in USD million (2019-2032)
• Table 12: Pelacarsen Market Size in Japan, in USD million (2019-2032)

List of Figures

• Figure 1: Pelacarsen Market Size in the 7MM, USD million (2019-2032)
• Figure 2: Pelacarsen Market Size in the United States, USD million (2019-2032)
• Figure 3: Pelacarsen Market Size in Germany, USD million (2019-2032)
• Figure 4: Pelacarsen Market Size in France, USD million (2019-2032)
• Figure 5: Pelacarsen Market Size in Italy, USD million (2019-2032)
• Figure 6: Pelacarsen Market Size in Spain, USD million (2019-2032)
• Figure 7: Pelacarsen Market Size in the United Kingdom, USD million (2019-2032)
• Figure 8: Pelacarsen Market Size in Japan, USD million (2019-2032)

"Pelacarsen Market Size, Forecast, and Emerging Insight - 2032" report provides comprehensive insights about pelacarsen for myocardial infarction in the seven major markets. A detailed picture of the pelacarsen for myocardial infarction in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the pelacarsen for myocardial infarction. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the pelacarsen market forecast analysis for myocardial infarction in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in myocardial infarction.

Drug Summary:

Pelacarsen (TQJ230), also known as IONIS-APO(a)-LRx, AKCEA-APO(a)-LRx, and TQJ230, is an investigational antisense medicine designed to reduce apolipoprotein(a) in the liver to offer a direct approach for reducing lipoprotein(a), or Lp (a)-a very atherogenic and thrombogenic form of LDL. Elevated Lp (a) is recognized as an independent genetic cause of coronary artery disease, heart attack, stroke, and peripheral arterial disease. Currently, there is no effective drug therapy to significantly lower elevated levels of Lp (a). Lp (a) levels are determined at birth; lifestyle modification, including diet and exercise, does not impact Lp (a) levels. Even patients who can control their LDL-C remain at high risk of cardiovascular events if they have high levels of Lp (a).

Pelacarsen is being developed for patients at significant risk of CVD because of their elevated Lp (a). Pelacarsen is the first drug in clinical development designed to selectively and robustly inhibit the production of Lp (a).

As per the company's Q3 2022 investor presentation, Novartis plans filing as well as data readouts of pelacarsen in 2025.

Scope of the Report:

The report provides insights into:

• A comprehensive product overview including the pelacarsen description, mechanism of action, dosage and administration, research and development activities in myocardial infarction.
• Elaborated details on pelacarsen regulatory milestones and other development activities have been provided in this report.
• The report also highlights the pelacarsen research and development activities in myocardial infarction across the United States, Europe and Japan.
• The report also covers the patents information with expiry timeline around pelacarsen.
• The report contains forecasted sales of pelacarsen for myocardial infarction till 2032.
• Comprehensive coverage of the late-stage emerging therapies for myocardial infarction.
• The report also features the SWOT analysis with analyst views for pelacarsen in myocardial infarction.

Methodology:

The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.

Pelacarsen Analytical Perspective by DelveInsight

• In-depth Pelacarsen Market Assessment

This report provides a detailed market assessment of pelacarsen for myocardial infarction in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2026 to 2032.

• Pelacarsen Clinical Assessment

The report provides the clinical trials information of pelacarsen for myocardial infarction covering trial interventions, trial conditions, trial status, start and completion dates.

Report Highlights:

• In the coming years, the market scenario for myocardial infarction is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
• The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence pelacarsen dominance.
• Other emerging products for myocardial infarction are expected to give tough market competition to pelacarsen and launch of late-stage emerging therapies in the near future will significantly impact the market.
• A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of pelacarsen in myocardial infarction.
• Our in-depth analysis of the forecasted sales data of pelacarsen from 2026 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the pelacarsen in myocardial infarction.

Key Questions:

• What is the product type, route of administration and mechanism of action of pelacarsen?
• What is the clinical trial status of the study related to pelacarsen in myocardial infarction and study completion date?
• What are the key collaborations, mergers and acquisitions, licensing and other activities related to the pelacarsen development?
• What are the key designations that have been granted to pelacarsen for myocardial infarction?
• What is the forecasted market scenario of pelacarsen for myocardial infarction?
• What are the forecasted sales of pelacarsen in the seven major countries, including the United States, Europe (Germany, France, Italy, Spain, and the United Kingdom), and Japan?
• What are the other emerging products available and how are these giving competition to pelacarsen for myocardial infarction?
• Which are the late-stage emerging therapies under development for the treatment of myocardial infarction?

Table of Contents

1. Report Introduction

2. Pelacarsen Overview in myocardial infarction

• 2.1. Product Detail
• 2.2. Clinical Development
  • 2.2.1. Clinical studies
  • 2.2.2. Clinical trials information
  • 2.2.3. Safety and efficacy
• 2.3. Other Developmental Activities
• 2.4. Product Profile

3. Competitive Landscape (Marketed Therapies)

4. Competitive Landscape (Late-stage Emerging Therapies)

5. Pelacarsen Market Assessment

• 5.1. Market Outlook of Pelacarsen in myocardial infarction
• 5.2. 7MM Analysis
  • 5.2.1. Market Size of Pelacarsen in the 7MM for myocardial infarction
• 5.3. Country-wise Market Analysis
  • 5.3.1. Market Size of Pelacarsen in the United States for myocardial infarction
  • 5.3.2. Market Size of Pelacarsen in Germany for myocardial infarction
  • 5.3.3. Market Size of Pelacarsen in France for myocardial infarction
  • 5.3.4. Market Size of Pelacarsen in Italy for myocardial infarction
  • 5.3.5. Market Size of Pelacarsen in Spain for myocardial infarction
  • 5.3.6. Market Size of Pelacarsen in the United Kingdom for myocardial infarction
  • 5.3.7. Market Size of Pelacarsen in Japan for myocardial infarction

6. SWOT Analysis

7. Analysts' Views

8. Appendix

• 8.1. Bibliography
• 8.2. Report Methodology

9. DelveInsight Capabilities

10. Disclaimer

11. About DelveInsight

12. Report Purchase Options