XPOVIO医薬品の考察と市場予測 - 2032年

当レポートでは、主要7市場（米国、ドイツ、フランス、イタリア、スペイン、英国、日本）におけるXPOVIOについて調査分析し、作用機序、用法と用量、研究開発活動に関する考察や、市場予測などを提供しています。

目次

第1章 レポートのイントロダクション

第2章 DLBCLにおけるXPOVIOの概要

• 製品の詳細
• 臨床開発
  • 臨床研究
  • 臨床試験情報
  • 安全性と有効性
• 規制上のマイルストーン
• その他の開発活動
• 製品のプロファイル

第3章 競合情勢（上市済みの治療法）

第4章 競合情勢（後期の新治療法）

第5章 XPOVIO市場の評価

• DLBCL向けXPOVIOの市場見通し
• 主要7市場の分析
  • 主要7市場のDLBCL向けXPOVIOの市場規模
• 市場の分析：国別
  • 米国のDLBCL向けXPOVIOの市場規模
  • ドイツのDLBCL向けXPOVIOの市場規模
  • 英国のDLBCL向けXPOVIOの市場規模

第6章 SWOT分析

第7章 アナリストの見解

第8章 付録

第9章 DelveInsightのサービス内容

第10章 免責事項

第11章 DelveInsightについて

第12章 レポート購入オプション

List of Tables

• Table 1: XPOVIO, Clinical Trial Description, 2023
• Table 2: XPOVIO, General Description
• Table 3: Competitive Landscape (Marketed Therapies)
• Table 4: Competitive Landscape (Emerging Therapies)
• Table 5: XPOVIO Market Size in the 7MM, in USD million (2019-2032)
• Table 6: XPOVIO Market Size in the US, in USD million (2019-2032)
• Table 7: XPOVIO Market Size in Germany, in USD million (2019-2032)
• Table 8: XPOVIO Market Size in France, in USD million (2019-2032)
• Table 9: XPOVIO Market Size in Italy, in USD million (2019-2032)
• Table 10: XPOVIO Market Size in Spain, in USD million (2019-2032)
• Table 11: XPOVIO Market Size in the UK, in USD million (2019-2032)
• Table 12: XPOVIO Market Size in Japan, in USD million (2019-2032)

List of Figures

• Figure 1: XPOVIO Market Size in the 7MM, USD million (2019-2032)
• Figure 2: XPOVIO Market Size in the United States, USD million (2019-2032)
• Figure 3: XPOVIO Market Size in Germany, USD million (2019-2032)
• Figure 4: XPOVIO Market Size in France, USD million (2019-2032)
• Figure 5: XPOVIO Market Size in Italy, USD million (2019-2032)
• Figure 6: XPOVIO Market Size in Spain, USD million (2019-2032)
• Figure 7: XPOVIO Market Size in the United Kingdom, USD million (2019-2032)
• Figure 8: XPOVIO Market Size in Japan, USD million (2019-2032)

"XPOVIO Drug Insight and Market Forecast - 2032" report provides comprehensive insights about XPOVIO for Diffuse Large B-cell lymphoma (DLBCL) in the seven major markets. A detailed picture of the XPOVIO for DLBCL in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the XPOVIO for DLBCL. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the XPOVIO market forecast analysis for DLBCL in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in DLBCL.

Drug Summary:

XPOVIO (selinexor) is a first-in-class, oral selective inhibitor of nuclear export (SINE) compound. It functions by binding with and inhibiting the nuclear export protein XPO1 (also called CRM1), leading to the accumulation of tumor suppressor proteins in the cell nucleus. This reinitiates and amplifies their tumor suppressor function and is believed to lead to the selective induction of apoptosis in cancer cells while largely sparing normal cells.

XPOVIO is also being studied in patients with R/R DLBCL and reported positive top-line results from the Phase IIb SADAL study evaluating XPOVIO in patients with relapsed or refractory DLBCL after at least two prior multi-agent therapies and who are ineligible for transplantation, including high dose chemotherapy with stem cell rescue.

Recently, the FDA granted accelerated approval to XPOVIO for adult patients with R/R DLBCL, not otherwise specified, including DLBCL arising from follicular lymphoma, after at least two lines of systemic therapy. This indication was approved under accelerated approval based on the response rate. Continued approval for these indications may be contingent upon verifying and describing clinical benefits in confirmatory trials.

Scope of the Report:

The report provides insights into:

• A comprehensive product overview including the XPOVIO description, mechanism of action, dosage and administration, research and development activities in Diffuse Large B-cell lymphoma (DLBCL).
• Elaborated details on XPOVIO regulatory milestones and other development activities have been provided in this report.
• The report also highlights the XPOVIO research and development activities in DLBCL across the United States, Europe and Japan.
• The report also covers the patents information with expiry timeline around XPOVIO.
• The report contains forecasted sales of XPOVIO for DLBCL till 2032.
• Comprehensive coverage of the late-stage emerging therapies for DLBCL.
• The report also features the SWOT analysis with analyst views for XPOVIO in DLBCL.

Methodology:

The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.

XPOVIO Analytical Perspective by DelveInsight

In-depth XPOVIO Market Assessment

This report provides a detailed market assessment of XPOVIO for Diffuse Large B-cell lymphoma (DLBCL) in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2023 to 2032.

XPOVIO Clinical Assessment

The report provides the clinical trials information of XPOVIO for DLBCL covering trial interventions, trial conditions, trial status, start and completion dates.

Report Highlights:

• In the coming years, the market scenario for Diffuse Large B-cell lymphoma (DLBCL) is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
• The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence XPOVIO dominance.
• Other emerging products for DLBCL are expected to give tough market competition to XPOVIO and launch of late-stage emerging therapies in the near future will significantly impact the market.
• A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of XPOVIO in DLBCL.
• Our in-depth analysis of the forecasted sales data of XPOVIO from 2023 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the XPOVIO in DLBCL.

Key Questions:

• What is the product type, route of administration and mechanism of action of XPOVIO?
• What is the clinical trial status of the study related to XPOVIO in Diffuse Large B-cell lymphoma (DLBCL) and study completion date?
• What are the key collaborations, mergers and acquisitions, licensing and other activities related to the XPOVIO development?
• What are the key designations that have been granted to XPOVIO for DLBCL?
• What is the forecasted market scenario of XPOVIO for DLBCL?
• What are the forecasted sales of XPOVIO in the seven major countries, including the United States, Europe (Germany, France, Italy, Spain, and the United Kingdom), and Japan?
• What are the other emerging products available and how are these giving competition to XPOVIO for DLBCL?
• Which are the late-stage emerging therapies under development for the treatment of DLBCL?

Table of Contents

1. Report Introduction

2. XPOVIO Overview in DLBCL

• 2.1. Product Detail
• 2.2. Clinical Development
  • 2.2.1. Clinical studies
  • 2.2.2. Clinical trials information
  • 2.2.3. Safety and efficacy
• 2.3. Regulatory Milestone
• 2.4. Other Developmental Activities
• 2.5. Product Profile

3. Competitive Landscape (Marketed Therapies)

4. Competitive Landscape (Late-stage Emerging Therapies)

5. XPOVIO Market Assessment

• 5.1. Market Outlook of XPOVIO in DLBCL
• 5.2. 7MM Analysis
  • 5.2.1. Market Size of XPOVIO in the 7MM for DLBCL
• 5.3. Country-wise Market Analysis
  • 5.3.1. Market Size of XPOVIO in the United States for DLBCL
  • 5.3.2. Market Size of XPOVIO in Germany for DLBCL
  • 5.3.3. Market Size of XPOVIO in France for DLBCL
  • 5.3.4. Market Size of XPOVIO in Italy for DLBCL
  • 5.3.5. Market Size of XPOVIO in Spain for DLBCL
  • 5.3.6. Market Size of XPOVIO in the United Kingdom for DLBCL
  • 5.3.7. Market Size of XPOVIO in Japan for DLBCL

6. SWOT Analysis

7. Analysts' Views

8. Appendix

• 8.1. Bibliography
• 8.2. Report Methodology

9. DelveInsight Capabilities

10. Disclaimer

11. About DelveInsight

12. Report Purchase Options