AXS-05：新薬の考察と市場予測 (2032年)

AXS-05は、マルチモーダルな活性を有する新規の経口NMDA受容体拮抗薬です。デキストロメトルファン (DM) とブプロピオンの独自の製剤と用量からなり、中枢神経系 (CNS) 疾患の治療薬として開発されています。

AXS-05は、現在、大うつ病性障害 (MDD) 、アルツハイマー病の興奮状態、禁煙の治療薬として開発されています。MDDとアルツハイマー病の焦燥感の両方について、米国FDAから画期的治療薬の指定を受けています。

当レポートでは、治療抵抗性うつ病の治療薬の一種であるAXS-05の市場構造・動向について分析し、製品の概要 (用法・容量、作用機序など) や関連規制、製品開発・治験の進行状況、主要7ヶ国 (米国、欧州5ヶ国 (ドイツ、フランス、イタリア、スペイン、英国)、日本) の市場規模の動向見通し (2022～2032年)、市場の競争状態・SWOT分析、他の治療薬との競合状態、今後の市場成長の可能性などを調査・考察しております。

目次

第1章 分析概要

第2章 治療抵抗性うつ病に向けAXS-05：概要

• 製品の詳細
• 臨床開発
  • 臨床研究
  • 治験情報
  • 安全性・有効性
• その他の開発活動
• 製品プロファイル

第3章 競合情勢 (後期段階の新興治療薬)

第4章 AXS-05の市場評価

• 治療抵抗性うつ病向けAXS-05：市場展望
• 主要7ヶ国 (MM7) の市場分析
  • 治療抵抗性うつ病向けAXS-05：主要7ヶ国の市場規模
• 国別の市場分析
  • 米国
  • ドイツ
  • 英国

第5章 SWOT分析

第6章 アナリストの見解

第7章 付録

第8章 DelveInsightのサービス内容

第9章 免責事項

第10章 DelveInsightについて

第11章 レポート購入オプション

List of Tables

• Table 1: BNC210, Clinical Trial Description, 2022
• Table 2: Competitive Landscape (Emerging Therapies)
• Table 3: AXS-05 Market Size in the 7MM, in USD million (2019-2032)
• Table 4: AXS-05 Market Size in the US, in USD million (2019-2032)
• Table 5: AXS-05 Market Size in Germany, in USD million (2019-2032)
• Table 6: AXS-05 Market Size in France, in USD million (2019-2032)
• Table 7: AXS-05 Market Size in Italy, in USD million (2019-2032)
• Table 8: AXS-05 Market Size in Spain, in USD million (2019-2032)
• Table 9: AXS-05 Market Size in the UK, in USD million (2019-2032)
• Table 10: AXS-05 Market Size in Japan, in USD million (2019-2032)

List of Figures

• Figure 1: Mechanism of Action of AXS-05
• Figure 2: AXS-05 Market Size in the 7MM, USD million (2019-2032)
• Figure 3: AXS-05 Market Size in the United States, USD million (2019-2032)
• Figure 4: AXS-05 Market Size in Germany, USD million (2019-2032)
• Figure 5: AXS-05 Market Size in France, USD million (2019-2032)
• Figure 6: AXS-05 Market Size in Italy, USD million (2019-2032)
• Figure 7: AXS-05 Market Size in Spain, USD million (2019-2032)
• Figure 8: AXS-05 Market Size in the United Kingdom, USD million (2019-2032)
• Figure 9: AXS-05 Market Size in Japan, USD million (2019-2032)

"AXS-05 Emerging Drug Insight and Market Forecast - 2032" report provides comprehensive insights about AXS-05 for Treatment Resistant Depression in seven major markets. A detailed picture of the AXS-05 for Treatment Resistant Depression in 7MM, i.e., United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan, for the study period 2019 -2032 is provided in this report along with a detailed description of the AXS-05 for Treatment Resistant Depression. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the AXS-05 market forecast analysis for Treatment Resistant Depression in 7MM, SWOT, analyst views, comprehensive overview of market competitors, and brief about other emerging therapies in Treatment Resistant Depression.

Drug Summary:

AXS-05 is a novel, oral, investigational NMDA receptor antagonist with multimodal activity. It consists of a proprietary formulation and dose of dextromethorphan (DM) and bupropion and is being developed to treat central nervous system (CNS) conditions.

• The dextromethorphan component of AXS-05 is an antagonist of the NMDA receptor, an ionotropic glutamate receptor, and a sigma-1 receptor agonist
• These actions modulate glutamatergic neurotransmission
• The bupropion component of AXS-05 serves primarily to increase the bioavailability of dextromethorphan and is a norepinephrine and dopamine reuptake inhibitor

AXS-05 is currently being developed to treat the major depressive disorder (MDD), Alzheimer's disease agitation, and smoking cessation. It has received Breakthrough Therapy designation from the FDA for both MDD and Alzheimer's disease agitation.

Scope of the Report:

The report provides insights into:

• A comprehensive product overview including the AXS-05 description, mechanism of action, dosage and administration, research and development activities in Treatment Resistant Depression.
• Elaborated details on AXS-05 regulatory milestones and other development activities have been provided in this report.
• The report also highlights the AXS-05 research and development activities in Treatment Resistant Depression across the United States, Europe and Japan.
• The report also covers the patents information with expiry timeline around AXS-05.
• The report contains forecasted sales of AXS-05 for Treatment Resistant Depression till 2032.
• Comprehensive coverage of the late-stage emerging therapies for Treatment Resistant Depression.
• The report also features the SWOT analysis with analyst views for AXS-05 in Treatment Resistant Depression.

Methodology:

The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.

AXS-05 Analytical Perspective by DelveInsight

• In-depth AXS-05 Market Assessment

This report provides a detailed market assessment of AXS-05 for Treatment Resistant Depression in seven major markets, i.e., United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan. This segment of the report provides forecasted sales data from 2022 to 2032.

• AXS-05 Clinical Assessment

The report provides the clinical trials information of AXS-05 for Treatment Resistant Depression covering trial interventions, trial conditions, trial status, start and completion dates.

Report Highlights:

• In the coming years, the market scenario for Treatment Resistant Depression is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
• The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence AXS-05 dominance.
• Other emerging products for Treatment Resistant Depression are expected to give tough market competition to AXS-05 and launch of late-stage emerging therapies in the near future will significantly impact the market.
• A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of AXS-05 in Treatment Resistant Depression.
• Our in-depth analysis of the forecasted sales data of AXS-05 from 2022 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the AXS-05 in Treatment Resistant Depression.

Key Questions

• What is the product type, route of administration and mechanism of action of AXS-05?
• What is the clinical trial status of the study related to AXS-05 in Treatment Resistant Depression and study completion date?
• What are the key collaborations, mergers and acquisitions, licensing and other activities related to the AXS-05 development?
• What are the key designations that have been granted to AXS-05 for Treatment Resistant Depression?
• What is the forecasted market scenario of AXS-05 for Treatment Resistant Depression?
• What are the forecasted sales of AXS-05 in the seven major countries, including the United States, Europe (Germany, France, Italy, Spain, and the United Kingdom), and Japan?
• What are the other emerging products available and how are these giving competition to AXS-05 for Treatment Resistant Depression?
• Which are the late-stage emerging therapies under development for the treatment of Treatment Resistant Depression?

Table of Contents

1. Report Introduction

2. AXS-05 overview in Treatment Resistant Depression

• 2.1. Product Detail
• 2.2. Clinical Development
  • 2.2.1. Clinical Studies
  • 2.2.2. Clinical Trials Information
  • 2.2.3. Safety and Efficacy
• 2.3. Other Developmental Activities
• 2.4. Product Profile

3. Competitive Landscape (Late-stage Emerging Therapies)

4. AXS-05 Market Assessment

• 4.1. Market Outlook of AXS-05 in Treatment Resistant Depression
• 4.2. 7MM Market Analysis
  • 4.2.1. Market Size of AXS-05 in the 7MM for Treatment Resistant Depression
• 4.3. Country-wise Market Analysis
  • 4.3.1. Market Size of AXS-05 in the United States for Treatment Resistant Depression
  • 4.3.2. Market Size of AXS-05 in Germany for Treatment Resistant Depression
  • 4.3.3. Market Size of AXS-05 in France for Treatment Resistant Depression
  • 4.3.4. Market Size of AXS-05 in Italy for Treatment Resistant Depression
  • 4.3.5. Market Size of AXS-05 in Spain for Treatment Resistant Depression
  • 4.3.6. Market Size of AXS-05 in the United Kingdom for Treatment Resistant Depression
  • 4.3.7. Market Size of AXS-05 in Japan for Treatment Resistant Depression

5. SWOT Analysis

6. Analysts' Views

7. Appendix

• 7.1. Bibliography
• 7.2. Report Methodology

8. DelveInsight Capabilities

9. Disclaimer

10. About DelveInsight

11. Report Purchase Options