市場調査レポート
商品コード
1116921
流行性角結膜炎(EKC)市場 - 市場の洞察、疫学、市場予測:2032年Epidemic keratoconjunctivitis (EKC)-Market Insights, Epidemiology, and Market Forecast-2032 |
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流行性角結膜炎(EKC)市場 - 市場の洞察、疫学、市場予測:2032年 |
出版日: 2022年08月01日
発行: DelveInsight
ページ情報: 英文 79 Pages
納期: 1~3営業日
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主要7ヶ国における流行性角結膜炎(EKC)の市場規模は、2021年に1,751万米ドルとなりました。日本が最大の市場規模となっています。また欧州4ヶ国ではドイツが21万米ドルと最大規模を有しています。
当レポートでは、主要7ヶ国における流行性角結膜炎(EKC)市場について調査し、市場の概要とともに、疫学、患者動向、新たな治療法、2032年までの市場規模予測、および医療のアンメットニーズなどを提供しています。
DelveInsight's, 'Epidemic keratoconjunctivitis (EKC)-Market Insights, Epidemiology, and Market Forecast-2032' report delivers an in-depth understanding of the EKC, historical and forecasted epidemiology as well as the EKC market trends in the United States, EU-5 (Germany, France, Italy, Spain, and the United Kingdom) and Japan.
The EKC market report provides current treatment practices, emerging drugs, and market share of the individual therapies, current and forecasted 7MM EKC market size from 2019 to 2032. The Report also covers current EKC treatment practice, SWOT analysis, reimbursement, and market access, and unmet medical needs to curate the best of the opportunities and assesses the underlying potential of the market.
Study Period: 2019-2032
EKC Overview
Keratoconjunctivitis is when the patient has both keratitis and conjunctivitis simultaneously. Keratitis is inflammation of the cornea, the clear dome covering the iris and the pupil. Conjunctivitis is inflammation of the conjunctiva.
Epidemic keratoconjunctivitis (EKC) is a highly contagious viral conjunctivitis. It is caused by a group of viruses known as adenoviruses that, in addition to ocular surface infections, are responsible for causing infectious diseases of the gastrointestinal tract and respiratory system illnesses such as the common cold virus (Couser & Kolluru, n.d.). EKC has a long incubation period and is highly contagious, leading to large outbreaks worldwide. It easily spreads where people are in close quarters, like schools, hospitals, and even doctors' offices.
The disease pathology includes the inflammation of the conjunctiva (conjunctivitis) and the cornea (keratitis). Two dilemmas are associated with this disease, first is that the virus in the early stage of incubation is asymptomatic, which leads to easy direct spread to other humans in contact; second, to date, no treatment exists with approved effect against EKC.
The adenovirus pathogen causes EKC. Adenoviral conjunctivitis is the most common cause of red-eye in the world. A study at the Wills Eye Hospital emergency room found a 62% prevalence of adenoviral conjunctivitis amongst all patients presenting with a clinical diagnosis of infectious conjunctivitis, while various other studies have demonstrated a prevalence of between 15% and 70% of all conjunctivitis worldwide.
More than 50 different adenovirus serotypes have been identified and divided into distinct subgroups. Specific adenovirus serotypes are associated with various types of ocular infection. The most common adenoviral conjunctivitis include EKC, pharyngoconjunctival fever, and nonspecific follicular conjunctivitis (simple adenoviral conjunctivitis). EKC is commonly associated with adenovirus serotypes 8, 19, and 37 and is considered a more critical form of adenoviral keratoconjunctivitis because of the adverse consequences it may have on visual acuity.
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EKC Diagnosis
Epidemic keratoconjunctivitis (EKC) can usually be diagnosed with a simple eye exam. A lighted magnifying glass, called a slip lamp, can check for characteristic signs of EKC, such as corneal opacity and subepithelial infiltrates. The practitioner may also check for swollen lymph nodes in the neck. A slit lamp in conjunction with magnifying lenses or an ophthalmoscope may be used to check the back of the eye if the symptoms are severe or persistent. In most cases, treatment would begin if the symptoms are uncomplicated. If the diagnosis is uncertain or the presentation of symptoms is unusual, the healthcare provider can use a simple, in-office test to detect the presence of adenovirus in the eye.
The diagnosis of EKC is based mainly on history and clinical picture, but cell culture in combination with immunofluorescence staining (CC-IFA) is a good tool for diagnosis. As well as Polymerase Chain Reaction (PCR) is very specific in the detection of adenovirus antigen. These methods are the most accurate way to confirm the diagnosis; however, many physicians lack diagnostic lab orders due to the cost and time delay. Rapid diagnosis of EKC has evolved with Rapid Pathogen Screening (RPS) Adeno Detector with instant results, and it is useful in the exact diagnosis of EKC patients in the office. EKC is a self-limiting disease that spontaneously resolves within 1-3 weeks without significant complications, but in 20-50% of cases, corneal infiltrates can persist for some weeks or even months and sometimes up to 2 years, which leads to a drop in visual acuity and significant glare as well as conjunctival scarring and symblepharon may happen in case of membranous conjunctivitis a vascular or visceral cause are often found writhing in pain, unable to find a comfortable position.
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EKC Treatment
Epidemic keratoconjunctivitis (EKC) is usually a self-limiting disease, and it tends to resolve spontaneously within 1-3 weeks without leaving any significant complications. There is no effective treatment for EKC. Depending upon the severity of signs and symptoms, patients are followed up for several days to weeks. The goals of pharmacotherapy (treatment with medicines) are to reduce morbidity and prevent any complications.
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The disease epidemiology covered in the report provides historical as well as forecasted epidemiology segmented by Total Incident Cases of Viral conjunctivitis, Total Adenovirus D-specific Incident Cases, Total Incident Cases of Epidemic keratoconjunctivitis (EKC), and Total Diagnosed Incident Cases of Epidemic keratoconjunctivitis (EKC) scenario in the 7MM covering the United States, EU-5 countries (Germany, France, Italy, Spain, and the United Kingdom) and Japan from 2019 to 2032.
Key Findings
The epidemiology segment also provides the EKC epidemiology data and findings across the United States, EU-5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.
Epidemic keratoconjunctivitis (EKC) is a self-limiting, infectious, viral, and highly contagious ocular condition that starts unilaterally and later develops into a bilateral condition. Adenovirus is the causative agent for this infection. During EKC infection, a patient has symptoms of both keratitis and conjunctivitis simultaneously. Some typical signs of EKC include conjunctival hyperemia/erythema (redness) of bulbar conjunctiva and/or palpebral conjunctiva; epithelial keratitis; chemosis (conjunctival edema); photophobia; foreign body sensation, etc. Other than these ocular symptoms, some of the systemic symptoms associated with EKC are lymphadenopathy (swollen lymph nodes, specifically the preauricular lymph nodes); fever; headache; and fatigue.
Currently, there is no approved therapy for the treatment of EKC patients. Treatment strategies focus on providing symptomatic relief to the patients. Along with providing symptomatic treatment, the focus is also put on preventing disease transmission. Anti-inflammatory and antiviral drugs in the form of eye drops or ocular gels are prominently used for the treatment of EKC patients. At times, more specifically in the case of younger patients, antibacterial eye drops are also recommended to prevent chances of mixed infection with bacterial agents.
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Key Findings
This section provides the total EKC market size in the United States.
The total EKC market size in Germany, France, Italy, Spain, and the United Kingdom are provided in this section.
The total EKC market size in Japan are provided.
Competitive Intelligence Analysis
We perform competitive and market Intelligence analysis of the EKC market by using various competitive intelligence tools that include-SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies, etc. The inclusion of the analysis entirely depends upon the data availability.
Key Questions
Market Insights:
Epidemiology Insights:
Current Treatment Scenario, Marketed Drugs, and Emerging Therapies: