ポリメラーゼ連鎖反応市場 - 市場の洞察、競合情勢、市場予測：2027年
Polymerase Chain Reaction- Market Insights, Competitive Landscape and, Market Forecast - 2027
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|ポリメラーゼ連鎖反応市場 - 市場の洞察、競合情勢、市場予測：2027年
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Polymerase Chain Reaction Market By Type (Conventional PCR, Real-Time RT-PCR, Digital PCR, Others) By Application (Infectious Diseases, Cancer, Hereditary Disorders, And Others), By End-User (Hospitals & Clinics, Academic & Research Labs, Others) and by geography is estimated to register growth at a remarkable CAGR forecast during 2022-2027 owing to rise in the prevalence of infectious diseases, increased applications in clinical diagnostics, and constant advancements in pcr technology for efficient use in biomedical sciences.
The Global Polymerase Chain Reaction market was valued at USD 4.90 billion in 2021, growing at a CAGR of 8.66% during the forecast period from 2022 to 2027 to reach USD 8.04 billion by 2027. The Polymerase Chain Reaction market is slated to witness increasing revenue owing to factors such as a rise in the prevalence of diseases caused by pathogens, increasing applications in the field of clinical diagnostics, along with latest technological advancements to further enhance its accuracy is expected to result in appreciable revenue growth in the Polymerase Chain Reaction market during the forecast period (2022-2027).
One of the noteworthy drivers of the Polymerase Chain Reaction market is the increasing use of PCR techniques in the clinical diagnostics sector. The use of the real-time RT-PCR technique as a way to detect the presence of SARS-CoV during the COVID-19 pandemic has proved to be a boon for the healthcare industry. According to the World Health Organization (2019), the RT-PCR technique is the golden standard for the detection of SARS coronavirus. For instance, as per reports from World Health Organization (2022), there have been 540,923,532 confirmed cases of COVID-19 worldwide, and every case was detected through the use of an RT-PCR test. The main reasons associated with the use of the RT-PCR technique are its high sensitivity and specificity. Not only is the RT-PCR solely applicable for the detection of COVID-19, but it is also used in oncology for the detection of cancer cells. For example, according to the Annals of Surgery (2019), RT-PCR was the most effective technique for the observation of circulating cancer cells in cases of colorectal cancer.
One of the other prominent factors responsible for the growth of the Polymerase Chain Reaction Market is its increasing use in the diagnosis of genetic disorders. For example, according to the Swedish Agency for Health Technology Assessment and Assessment of Social Services (2019), the RT-PCR technique has replaced most of the conventional diagnostic methods in 80% of suspected cases of genetic disorders. Another key factor responsible for the growth of the Polymerase Chain Reaction market is the continuous technological advancements taking place in PCR technology to improve product efficacy. For instance, in December 2020, Stilla Technologies launched a Polymerase Chain Reaction Mix reagent line for optimal performance with Crystal Digital PCR (nacia multiplex PCR Mix and nacia PCR Mix), which are optimized for better results and robustness for digital PCR applications.
In a similar development, in March 2021, PCR Biosystems, specialists in DNA and RNA analysis launched a set of IsoFast Bst Polymerase reagents for rapid, robust DNA & RNA amplification. However, the availability of alternative therapies and the high cost of the Polymerase Chain Reaction machine and reagents may act as restraining factors to the Polymerase Chain Reaction market growth.
The Polymerase Chain Reaction market reported a period of rapid market growth due to the COVID-19 pandemic. The COVID-19 pandemic resulted in the massive reorganization of the healthcare services and carrying out of medical procedures, where the RT-PCR test reports were the measure for the detection of infection, as per the World Health Organization (2019). All the key market players involved in the Polymerase Chain Reaction Market experienced robust growth in their revenue during the phases of COVID-19. For example, according to the annual report of Thermo Fisher Scientific Corporation (2020), the revenue share of the company increased by 26% to 32.22 billion USD, and the GAAP diluted EPS increased by 74%, as compared to 2018. In another instance, according to the Qiagen Annual Report (2020), Qiagen saw a jump in its revenue share by 22.53% as compared to 2018. Although the global COVID-19 cases reducing, still Polymerase Chain Reaction based test is on the rise because of their constant applications in clinical diagnostics and research, which is uplifting the Polymerase Chain Reaction market growth during the forecast period from 2022-2027.
Polymerase Chain Reaction Market by Type (Conventional PCR, Real-time RT-PCR, Digital PCR, and Others), Application (Infectious diseases, Cancer, Hereditary disorders, and Others), End-user (Hospitals & Clinics, Academic & Research Labs, Others), Geography (North-America, Europe, Asia-Pacific, Rest of the World)
Based on the Application segment of the Polymerase Chain Reaction Market, the infectious diseases category is projected to register significant growth in revenue in the Polymerase Chain Reaction market during the forecast period (2022-2027). This can be ascribed to the increasing prevalence of infectious diseases caused by viruses, bacteria, fungi, and other pathogens. With one of the most infectious and recent examples of infectious disease being COVID-19, other hazardous diseases caused by pathogens are HIV AIDS, and Tuberculosis, caused by viruses and bacteria respectively. As per reports from World Health Organization (2021), there were 37.7 billion cases of HIV-AIDS globally, by the end of 2020.
The RT-PCR technique is regarded as the alternative gold standard for the detection of HIV AIDS. In cases of bacterial infection diseases like Tuberculosis, the RT-PCR technique shows high sensitivity and specificity during diagnosis. The RT-PCR technique also has its advantages in oncological studies. As per reports from World Health Organization (2022) cancer accounted for approximately 10 million deaths, in the year 2020. According to the same source, one of the primary reasons for cancer deaths was the late diagnosis of the disease, to which the Polymerase Chain Reaction appears to be the fastest and most sensitive test for the detection of tumors.
Therefore, considering the growing demand for this product type, numerous new products are being launched in the market with technological advancements. For example, in March 2021, MatMa Corporation launched MYRTA, a new hand-held Real-Time RT-PCR device for Point-of-Care (POC) and Over-the-Counter (OTC) molecular diagnostics.
Thus, considering the rising prevalence of various infectious diseases and their growing popularity among end users, the application segment is expected to generate considerable revenue thereby pushing the overall growth of the global Polymerase Chain Reaction market during the forecast period.
Among all the regions, North America is expected to lead in revenue generation in the global Polymerase Chain Reaction market. This can be ascribed to the growing prevalence of infectious diseases and the increasing number of clinical research studies in the North American region. According to the Centre for Disease Prevention and Control (2022), 6 in 10 people in the United States were burdened with a chronic disease, and 4 in 10 people had two or more diseases in the year 2021. The World Health Organization (2022) statistics show that the COVID-19 pandemic has severly impacted the U.S., with 88,932,987 cases and 1,018,035 deaths, by July 14, 2022. Due to such a high prevalence of infectious diseases in the United States, it expands the way for more amount of clinical studies and the latest diagnostic technological developments.
One of the other prominent factors supporting the growth of the North America Polymerase Chain Reaction market is the rising case of genetic disorders in the North American region. As per reports from the Centre for Disease Control and Prevention (2021), millions of people are affected by inherited genetic disorders such as cystic fibrosis, sickle-cell anemia, Lynch syndrome, etc. every year. Some genetic disorders are not diagnosed at birth but lead to severe consequences at a later stage due to late detection of the syndrome. For example, the report from the World Health Organization, Regional Office for the Eastern Mediterranean (2022), shows that cases with genetic disorders account for 2%-5% of all live births, 30% of the affected account for hospital admissions at a later stage, and 50% account for deaths during childhood in the year 2020, in industrialized countries.
The presence of a large patient population base in the North American region, also opens up the way for new technologies and collaborations to take place in clinical diagnostics areas. For example, in June 2021, Bio-Rad collaborated with Seegene Inc. for the production of molecular diagnostic products related to infectious diseases. Through this collaboration, Seegene started to provide diagnostic tests for use on Bio-Rad's LFX960x Real-Time PCR System for commercial use in the U.S. market. In another instance, according to the American Chemical Society (2021), researchers devised a postage stamp-sized polydimethylsiloxane chip with microchambers arrays in the PCR. Although the amplification efficiency of the chip-encoded PCR was 91% as compared to 98% in standard PCR, the chip-encoded PCR takes approximately 5 minutes for detection as compared to an hour in conventional PCRs. The source further stated that the technique will get commercialized in the future and could be used for rapid detection diagnosis during severe cases of pandemics.
Therefore, the presence of a large patient population base with infectious diseases and genetic disorders, coupled with a rise in technological advancements and clinical research studies is expected to bolster the growth of the Polymerase Chain Reaction market in the North American region during the forecast period.
Some of the key market players operating in the Polymerase Chain Reaction market include Thermo Fisher Scientific Inc., Bio-Rad Laboratories Inc., Qiagen, Agilent Technologies Inc., Standard Biotools, F. Hoffmann-La Roche Ltd., Eppendorf, Avance Biosciences Inc., Merck & Co. Inc., Abbott, Promega Corporation, Takara Bio Inc., Endress+Hauser Group Services AG, BioMerieux, GenMark Diagnostics Inc., Grifols SA, Hologic Inc., BD, Sysmex Corporation, Stilla, and others.