セルベースアッセイの世界市場と技術

世界のセルベースアッセイの市場規模は、2022年に292億米ドルとなりました。

同市場は、2022年～2027年の予測期間中に10.2％のCAGRで拡大し、2027年には473億米ドルに達すると予測されています。

当レポートでは、世界のセルベースアッセイ市場について調査し、市場の概要とともに、用途別、セグメント別、エンドユーザー別、地域別動向、COVID-19の影響、および市場に参入する企業のプロファイルなどを提供しています。

目次

第1章 イントロダクション

第2章 まとめとハイライト

第3章 概要

第4章 創薬のためのアッセイ

• ADME/Toxスクリーニングのための細胞ベースのアプローチ
• 市場機会
• ADMEと毒性スクリーニング
• マルチプレックスセルベースアッセイ
• セルベースアッセイのためのハイスループット画像処理プラットフォーム
• 今日の創薬プロセスにおける細胞アッセイ
• ラベルフリー細胞アッセイ：創薬の未来
• 結論

第5章 セルベースアッセイ：現在の技術

第6章 セルベースアッセイの商品化

• セルベースアッセイの役割
• セルベースアッセイの需要
• 創薬とセルベースアッセイ
• 市場採用の機会
• 細胞増殖の測定
• 細胞増殖アッセイを提供している企業
• 幹細胞と免疫細胞別治療への移行
• 細胞ベースのスクリーニングアッセイ
• オーファン受容体
• 概要

第7章 市場力学

• セルベースアッセイの市場に影響を与える要因
• 市場の促進要因
• 市場の抑制要因

第8章 COVID-19の影響

• イントロダクション
• アウトブレイク
• COVID-19の症状
• COVID-19の進行
• 潜伏期間
• 疫学
• 組織と政府間のコラボレーション
• 病気の蔓延
• セルベースアッセイ市場に対するCOVID-19の影響

第9章 世界のセルベースアッセイ市場、用途別

• 現在の市場概要
• セルベースアッセイ
• セルベースアッセイ市場
• 用途
• 創薬
• 基礎研究
• ADMEと毒物学

第10章 世界のセルベースアッセイ市場、セグメント別

• 消耗品
• 装置
• ソフトウェア
• サービス

第11章 世界のセルベースアッセイ市場、エンドユーザー別

• バイオテクノロジー企業および製薬会社
• 学術研究機関
• CRO

第12章 世界のセルベースアッセイ市場、地域別

• 世界市場の概要
• 地域別市場
• 北米
• 欧州
• アジア太平洋
• その他の地域

第13章 競合情勢

第14章 企業プロファイル

• AGILENT TECHNOLOGIES INC.
• BECTON, DICKINSON & CO.
• BIOIVT
• BIO-RAD LABORATORIES
• CELL BIOLOGICS
• CELL BIOLABS INC.
• CELL SIGNALING TECHNOLOGY INC.
• CHARLES RIVER
• CORNING, INC.
• DANAHER
• DISCOVERX CORP.
• ENZO LIFE SCIENCES
• EVOTEC AG
• FUJIFILM CELLULAR DYNAMICS INC.(FCDI)
• GE HEALTHCARE
• LONZA
• MERCK KGAA
• ONCOLMMUNIN
• PERKINELMER
• PROMEGA CORP.
• THERMO FISHER SCIENTIFIC

List of Tables

• Summary Table A : Global Market for Cell-Based Assays, Through 2027
• Summary Table B : Global Market for Cell-Based Assays, by Application, Through 2027
• Table 1 : Uses of Cell-Based Assays by Area
• Table 2 : Types of Cell-based Assays
• Table 3 : Apoptotic Markers
• Table 4 : Proof of Concept for Cell-Based Assays
• Table 5 : Materials and Manufacturers of Hydrogels, by Type
• Table 6 : Minimum Requirements for Organ-on-a-Chip Units, by Type
• Table 7 : HCS Instrumentation Available in the Market, by Company
• Table 8 : HCS Informatics Tools Available in the Market, by Application
• Table 9 : Selected High-Throughput Instruments Available in the Market
• Table 10 : Assay Methods Used to Study GPCRs
• Table 11 : GPCR Primary Screening Assays
• Table 12 : Key GPCR Targeting Drugs
• Table 13 : Key Companies with GPCR Products
• Table 14 : Omeros' GPCRs and Their Indications
• Table 15 : Biological Assay Systems for the Evaluation of Cytochrome P450 Enzyme Isoforms
• Table 16 : Types of Hepatocyte Assay Systems
• Table 17 : Types of ADME Assays
• Table 18 : Common Types of Toxicity Assays
• Table 19 : Traditional Methods of ADME/Tox Testing
• Table 20 : Conventional In Vitro ADME/Tox Screening Methods
• Table 21 : Applications of Label-Free Assays
• Table 22 : Factors for Cell-Based Assay Development
• Table 23 : Approaches to Cell-Based Systems for Drug Screening
• Table 24 : Thermo Fisher's Products
• Table 25 : Thermo Fisher's Cell-Based Technologies
• Table 26 : List of Current Confocal HCS Platforms
• Table 27 : Widefield HCS Platforms, by Type
• Table 28 : List of Studies for Filing an Investigational New Drug Application
• Table 29 : List of Studies for Clinical Filings
• Table 30 : List of Existing Cell-Based Assay Technologies
• Table 31 : Limitations of Cell-Based Assays
• Table 32 : Biological Applications for High-Content Analysis
• Table 33 : Total Number of New Cases and Deaths Due to Various Cancers Globally, 2020
• Table 34 : U.S. NIH Funding for Various Disease Conditions, 2014-2020
• Table 35 : COVID-19 Clinical Symptom Distribution
• Table 36 : COVID-19 Confirmed Cases and Deaths, by WHO Region, June 15, 2022
• Table 37 : Global Market for Cell-Based Assays, Through 2027
• Table 38 : Global Market for Cell-Based Assays, by Application, Through 2027
• Table 39 : Global Market for Cell-Based Assays in Drug Discovery, by Region, Through 2027
• Table 40 : Global Market for Cell-Based Assays for Basic Research, by Region, Through 2027
• Table 41 : Global Market for Cell-Based Assays in ADME and Toxicology, by Region, Through 2027
• Table 42 : Global Market for Cell-Based Assays, by Segment, Through 2027
• Table 43 : Global Market for Consumables, by Region, Through 2027
• Table 44 : Global Market for Instruments, by Region, Through 2027
• Table 45 : Global Market for Software, by Region, Through 2027
• Table 46 : Global Market for Services, by Region, Through 2027
• Table 47 : Global Market for Cell-Based Assays, by End User, Through 2027
• Table 48 : Global Market for Cell-Based Assays Used by Pharmaceutical and Biotechnology Companies, by Region, Through 2027
• Table 49 : Global Market for Cell-Based Assays Used by Academic and Research Institutes, by Region, Through 2027
• Table 50 : Global Market for Cell-Based Assays Used by Contract Research Organizations, by Region, Through 2027
• Table 51 : Growth Drivers of the Cell-Based Assay Market
• Table 52 : Global Market for Cell-Based Assays, by Region, Through 2027
• Table 53 : North American Market for Cell-Based Assays, by Country, Through 2027
• Table 54 : European Market for Cell-Based Assays, by Country, Through 2027
• Table 55 : Asia-Pacific Market for Cell-Based Assays, by Country, Through 2027
• Table 56 : Mergers, Acquisitions and Collaborations, 2019-2022
• Table 57 : Competitive Analysis of the Market for Cell-Based Assays, 2021
• Table 58 : Becton, Dickinson & Company: Business Segment
• Table 59 : Charles River Laboratories: Business Segments
• Table 60 : Danaher: Business Segment
• Table 61 : Thermo Fisher Scientific Inc.: Business Segments

List of Figures

• Summary Figure A : Global Market for Cell-Based Assays, 2019-2027
• Summary Figure B : Global Market for Cell-Based Assays, by Application, 2019-2027
• Figure 1 : Projected Global Aging Population (65 Years and Above), 1990-2050
• Figure 2 : Drug Discovery Process Steps
• Figure 3 : Process Flow for Patient-Derived Organoid Cell Assay
• Figure 4 : Basic Architecture of Organ-on-a-Chip Systems
• Figure 5 : Cell Viability and Kinase Assays Used to Measure Change in ATP Levels
• Figure 6 : Distribution of Top 20 Diseases for Mesenchymal Stromal Cell-Related Clinical Studies, 2021
• Figure 7 : Distribution of Approved Drugs with Unique GPCRs, 2019
• Figure 8 : Personalized Medicines on the Market, 2008-2020
• Figure 9 : Global Pharmaceutical R&D Spending, 2010-2019
• Figure 10 : Global Market for Cell-Based Assays, by Application, 2019-2027
• Figure 11 : Global Market Shares of Cell-Based Assays, by Application, 2021
• Figure 12 : Global Market for Cell-Based Assays in Drug Discovery, by Region, 2019-2027
• Figure 13 : Global Market for Cell-Based Assays for Basic Research, by Region, 2019-2027
• Figure 14 : Phase Transition Success Rates and Likelihood of Approval from Phase I for All Diseases, All Modalities, 2011-2020
• Figure 15 : Global Market for Cell-Based Assays in ADME and Toxicology, by Region, 2019-2027
• Figure 16 : Global Market for Cell-Based Assays, by Segment, 2019-2027
• Figure 17 : Global Market Shares of Cell-Based Assays, by Segment, 2021
• Figure 18 : Global Market for Consumables, by Region, 2019-2027
• Figure 19 : Global Market for Instruments, by Region, 2019-2027
• Figure 20 : Global Market for Software, by Region, 2019-2027
• Figure 21 : Global Market for Services, by Region, 2019-2027
• Figure 22 : Global Market for Cell-Based Assays, by End User, 2019-2027
• Figure 23 : Global Market Shares of Cell-Based Assays, by End User, 2021
• Figure 24 : Biopharmaceuticals R&D Spending, 2010-2024
• Figure 25 : Global Market for Cell-Based Assays Used by Pharmaceutical and Biotechnology Companies, by Region, 2019-2027
• Figure 26 : Global Market for Cell-Based Assays for Academic and Research Institutes, by Region, 2019-2027
• Figure 27 : Global Market for Cell-Based Assays Used by Contract Research Organizations, by Region, 2019-2027
• Figure 28 : Global Market for Cell-Based Assays, by Region, 2019-2027
• Figure 29 : Global Market Shares of Cell-Based Assays, by Region, 2021
• Figure 30 : North American Market for Cell-Based Assays, by Country 2019-2027
• Figure 31 : U.S. Market for Cell-Based Assays, 2019-2027
• Figure 32 : Canadian Market for Cell-Based Assays, 2019-2027
• Figure 33 : European Market for Cell-Based Assays, by Country, 2020-2027
• Figure 34 : U.K. Market for Cell-Based Assays, 2019-2027
• Figure 35 : German Market for Cell-Based Assays, 2019-2027
• Figure 36 : French Market for Cell-Based Assays, 2019-2027
• Figure 37 : Italian Market for Cell-Based Assays, 2019-2027
• Figure 38 : Spanish Market for Cell-Based Assays, 2019-2027
• Figure 39 : Rest of the European Market for Cell-Based Assays, 2019-2027
• Figure 40 : Asia-Pacific Market for Cell-Based Assays, by Country, 2020-2027
• Figure 41 : Chinese Market for Cell-Based Assays, 2019-2027
• Figure 42 : Japanese Market for Cell-Based Assays, 2019-2027
• Figure 43 : Indian Market for Cell-Based Assays, 2019-2027
• Figure 44 : Rest of Asia-Pacific Market for Cell-Based Assays, 2019-2027
• Figure 45 : Rest of the World Market for Cell-Based Assays, 2019-2027
• Figure 46 : Becton, Dickinson & Company: Annual Revenue, 2019-2021
• Figure 47 : Becton, Dickinson & Company: Market Shares, by Region, 2021
• Figure 48 : Becton, Dickinson & Company: Market Shares, by Business Segment, 2021
• Figure 49 : Charles River Laboratories: Annual Revenue, 2019-2021
• Figure 50 : Charles River Laboratories: Market Share, by Region, 2021
• Figure 51 : Charles River Laboratories: Market Share, by Segment, 2021
• Figure 52 : Danaher: Annual Revenue, 2019-2021
• Figure 53 : Danaher: Diagnostic Segment Market Shares, by Region, 2021
• Figure 54 : Danaher: Market Shares, by Business Segment, 2021
• Figure 55 : Eurofins Pharma Discovery Services (Eurofins DiscoverX Products): Annual Revenue, 2019-2021
• Figure 56 : Eurofins DiscoverX Products: Market Share, by Region, 2021
• Figure 57 : General Electric Healthcare: Annual Revenue, 2019-2021
• Figure 58 : General Electric Healthcare: Market Shares, by Region/Country, 2021
• Figure 59 : General Electric Healthcare: Market Shares, by Business Segment, 2021
• Figure 60 : Lonza: Annual Revenue, 2020 and 2021
• Figure 61 : Lonza: Market Shares, by Business Segment, 2021
• Figure 62 : Merck KGaA: Annual Revenue, 2019-2021
• Figure 63 : Merck KGaA: Market Share, by Region, 2021
• Figure 64 : Merck KGaA: Market Share, by Segment, 2021
• Figure 65 : PerkinElmer: Annual Revenue, 2019-2021
• Figure 66 : PerkinElmer: Market Share, by Region/Country, 2021
• Figure 67 : PerkinElmer: Market Shares, by Business Unit, 2021
• Figure 68 : Thermo Fisher Scientific Inc.: Annual Revenue, 2019-2021
• Figure 69 : Thermo Fisher Scientific Inc.: Market Shares, by Region, 2021
• Figure 70 : Thermo Fisher Scientific Inc.: Market Shares, by Business Segment, 2021

Highlights:

The global cell-based assays market should reach $47.3 billion by 2027 from $29.2 billion in 2022 at a compound annual growth rate (CAGR) of 10.2% for the forecast period of 2022 to 2027.

The drug discovery segment of the global cell-based assays market is expected to grow from $20.9 billion in 2022 to $34.2 billion in 2027 at a CAGR of 10.3% for the forecast period of 2022 to 2027.

The basic research segment of the global cell-based assays market is expected to grow from $2.9 billion in 2022 to $4.9 billion in 2027 at a CAGR of 10.9% for the forecast period of 2022 to 2027.

Report Scope:

This report is an update of an earlier report of the same title. This report offers a comprehensive analysis of the global cell-based assays market. Segmentation is based on product, type/application and end user. Based on type/application, the market is segmented as drug discovery for validating drug targets/lead profiling assays, absorption, distribution, metabolism, and excretion (ADME) toxicity assays and basic research. The regional markets covered are North America, Europe, Asia-Pacific, and the Rest of the World (RoW).

The report provides a detailed overview and analysis of the present and future global market for cell-based assay techniques. The report analyzes in detail currently available cell-based assays and their markets. Industry growth drivers, restraints and opportunities are also discussed in detail. The report also provides information on competitive landscape, elaborative company profiles and the impact of COVID-19 on the market.

Report Includes:

• 63 tables
• An up-to-date review of the global markets for cell-based assays and related technologies
• Analyses of the global market trends, with historic sales data from 2019 to 2021, estimates for 2022, and projections of compound annual growth rates (CAGRs) through 2027
• Highlights of the current and future potential in the market for cell-based assays, and areas of focus to forecast this market into various segments and sub-segments
• Estimation of the actual market size for cell-based assays, revenue forecast, and corresponding market share analysis based on product, type/application, end user and geographic region
• Market assessment of the cell-based assays available and currently being used, new developments, spending trends, and revenue prospects for cell-based assays in the pharmaceutical industry
• Coverage of major issues involved in the research and development (R&D) of more effective cell-based approaches for drug discovery
• In-depth information on increasing investments on R&D activities, key technology issues, industry specific challenges, major types of end-user markets, and COVID-19 implications on the progress of this market
• Competitive analysis of the market for cell-based assays and updated information on the mergers, acquisitions, collaborations and recent developments during the 2020-2022 period
• Descriptive company profiles of the leading global players, including Becton, Dickinson & Company, Charles River Laboratories, General Electric Healthcare, Merck KGaA and Thermo Fisher Scientific Inc.

Table of Contents

Chapter 1 Introduction

• Study Goals and Objectives
• Reasons for Doing This Study
• What's New in This Update?
• Scope of Report
• Methodology
• Geographic Breakdown
• Analyst's Credentials
• BCC Custom Research
• Related BCC Research Reports

Chapter 2 Summary and Highlights

Chapter 3 Overview

• Introduction
• Overview: Cell-Based Assays
• Drug Discovery
• Tools for Drug Discovery
• High-Content Screening
• High-Content Screening Products
• Data Analysis
• Cell-Based Screening
• Proliferation Assays
• Apoptosis Assays
• Activation Assays
• Assays to Measure Gene Expression
• Proof of Concept for Cell-Based Assays
• Cell-Based Assays and Technology Trends
• Advancements in Cell-Based Assays
• Novel Cell-Based Assay Using Organoids, Scaffolds/Hydrogels and Organs-on-a-Chip
• Spheroids for Drug Development
• Label-Free Cell-Based Assay Technology Using Biolayer Interferometry
• Lineage Sequencing for Mutational Analysis and Cancer-Based Studies
• Evaluation of Hantavirus Replication Using In-Cell Western Assay
• Quantitative Cell-Based Assay Using a High-Content Analysis Platform
• High-Throughput Single-Cell Transcriptome Sequencing
• Ex Vivo Chemosensitivity Assays for Individualized Cancer Chemotherapy
• Luciferase-Based High-Throughput Screening Assay
• Functionally Relevant Morphological Profiling for Mesenchymal Stromal Cells
• G Protein-Coupled Receptors
• GPCRs: A Potent Class of Drug Targets
• GPCR Drugs
• Developments
• Cell-Based Assays: Screening Ion Channels

Chapter 4 Assays for Drug Discovery

• Cell-Based Approaches for ADME/Tox Screening
• Market Opportunities
• ADME and Toxicity Screening
• Multiplexed Cell-Based Assays
• High-Throughput Imaging-Based Platform for Cell-Based Assays
• Cell Assays in Today's Drug Discovery Process
• Label-Free Cellular Assays: The Relevant Future of Drug Discovery
• Conclusion

Chapter 5 Cell-Based Assays: Current Technologies

• Factors in Cell-Based Assay Development
• Reporter Gene Technology
• Cell-Based Assays for Studying Protein-Protein Interactions
• Cell-Based Protein-Fragment Complementation Assays
• Measuring Calcium Signaling
• Cell-Based Label-Free Approaches
• Label-Free Detection
• Companies
• Thermo Fisher
• CellSensor
• LanthaScreen
• Molecular Devices
• Automation and Miniaturization
• Cell Patterning
• Cell-Based Assays and Physiological Relevance
• Cell-Based Assays and Multiplexing
• Developing Reporter Assays
• Reporter Assays and Multiplexing
• Ultrahigh-Throughput Screening
• Development of the PathHunter Assay
• High-Content Screening Technology
• Imaging Cells for Cell-Based Assays
• Microscopic Visualization of Cells
• Quantum Dots
• Label-Free Imaging
• Investigational New Studies in Drug Development
• Role of ADME in Drug Design
• Prodrug Strategies
• Molecular Modeling
• Summary
• Limitations of Cell-Based Assays in the Risk Assessment Process
• Bottlenecks in Cell-Based Screening
• Methods to Improve Throughput in Cell-Based Assays
• New Technologies
• DataChip
• BIND Technology
• Miniaturization of Biological Assays
• Microfluidic Cell Culture Systems for Drug Research
• Conclusion

Chapter 6 Commercialization of Cell-Based Assays

• Role of Cell-Based Assays
• Demand for Cell-Based Assays
• Drug Discovery and Cell-Based Assays
• Opportunities for Market Adoption
• Measuring Cell Proliferation
• Companies Offering Cell Proliferation Assays
• Move toward Therapies with Stem and Immune Cells
• Cell-Based Screening Assays
• Orphan Receptors
• Summary

Chapter 7 Market Dynamics

• Factors Affecting the Market for Cell-Based Assays
• Market Drivers
• Market Restraints

Chapter 8 Impact of COVID-19

• Introduction
• Outbreak
• COVID-19 Symptoms
• Progression of COVID-19
• Incubation Period
• Epidemiology
• Collaboration between Organizations and Governments
• Spread of Disease
• Impact of COVID-19 on the Cell-Based Assay Market

Chapter 9 Global Market for Cell-Based Assays by Application

• Current Market Overview
• Cell-Based Assays
• Market for Cell-Based Assays
• Applications
• Drug Discovery
• Basic Research
• ADME and Toxicology

Chapter 10 Global Market for Cell-Based Assays by Segment

• Consumables
• Instruments
• Software
• Services

Chapter 11 Cell-Based Assays Market by End User

• Biotechnology and Pharmaceutical Companies
• Academic and Research Institutes
• Contract Research Organizations

Chapter 12 Global Market for Cell-Based Assays by Region

• Global Market Overview
• Regional Markets
• North America
• Europe
• Asia-Pacific
• Rest of the World (RoW)

Chapter 13 Competitive Landscape

• Mergers, Acquisitions, and Collaborations
• Recent Developments
• Competitive Analysis

Chapter 14 Company Profiles

• AGILENT TECHNOLOGIES INC.
• BECTON, DICKINSON & CO.
• BIOIVT
• BIO-RAD LABORATORIES
• CELL BIOLOGICS
• CELL BIOLABS INC.
• CELL SIGNALING TECHNOLOGY INC.
• CHARLES RIVER
• CORNING, INC.
• DANAHER
• DISCOVERX CORP.
• ENZO LIFE SCIENCES
• EVOTEC AG
• FUJIFILM CELLULAR DYNAMICS INC. (FCDI)
• GE HEALTHCARE
• LONZA
• MERCK KGAA
• ONCOLMMUNIN
• PERKINELMER
• PROMEGA CORP.
• THERMO FISHER SCIENTIFIC