キムリア医薬品の考察と市場予測 - 2032年

当レポートでは、主要7市場（米国、ドイツ、フランス、イタリア、スペイン、英国、日本）におけるキムリアについて調査分析し、作用機序、用法と用量、研究開発活動に関する考察や、市場予測などを提供しています。

目次

第1章 レポートのイントロダクション

第2章 DLBCL向けキムリアの概要

• 製品の詳細
• 臨床開発
  • 臨床研究
  • 臨床試験情報
  • 安全性と有効性
• 規制上のマイルストーン
• その他の開発活動
• 製品のプロファイル

第3章 競合情勢（上市済みの治療法）

第4章 競合情勢（後期の新治療法）

第5章 キムリア市場の評価

• DLBCL向けキムリアの市場見通し
• 主要7市場の分析
  • 主要7市場のDLBCL向けキムリアの市場規模
• 市場の分析：国別
  • 米国のDLBCL向けキムリアの市場規模
  • ドイツのDLBCL向けキムリアの市場規模
  • 英国のDLBCL向けキムリアの市場規模

第6章 SWOT分析

第7章 アナリストの見解

第8章 付録

第9章 DelveInsightのサービス内容

第10章 免責事項

第11章 DelveInsightについて

第12章 レポート購入オプション

List of Tables

• Table 1: KYMRIAH, Clinical Trial Description, 2023
• Table 2: KYMRIAH, General Description
• Table 3: Competitive Landscape (Marketed Therapies)
• Table 4: Competitive Landscape (Emerging Therapies)
• Table 5: KYMRIAH Market Size in the 7MM, in USD million (2019-2032)
• Table 6: KYMRIAH Market Size in the US, in USD million (2019-2032)
• Table 7: KYMRIAH Market Size in Germany, in USD million (2019-2032)
• Table 8: KYMRIAH Market Size in France, in USD million (2019-2032)
• Table 9: KYMRIAH Market Size in Italy, in USD million (2019-2032)
• Table 10: KYMRIAH Market Size in Spain, in USD million (2019-2032)
• Table 11: KYMRIAH Market Size in the UK, in USD million (2019-2032)
• Table 12: KYMRIAH Market Size in Japan, in USD million (2019-2032)

List of Figures

• Figure 1: KYMRIAH Market Size in the 7MM, USD million (2019-2032)
• Figure 2: KYMRIAH Market Size in the United States, USD million (2019-2032)
• Figure 3: KYMRIAH Market Size in Germany, USD million (2019-2032)
• Figure 4: KYMRIAH Market Size in France, USD million (2019-2032)
• Figure 5: KYMRIAH Market Size in Italy, USD million (2019-2032)
• Figure 6: KYMRIAH Market Size in Spain, USD million (2019-2032)
• Figure 7: KYMRIAH Market Size in the United Kingdom, USD million (2019-2032)
• Figure 8: KYMRIAH Market Size in Japan, USD million (2019-2032)

"KYMRIAH Drug Insight and Market Forecast - 2032" report provides comprehensive insights about KYMRIAH for Diffuse Large B-cell lymphoma (DLBCL) in the seven major markets. A detailed picture of the KYMRIAH for DLBCL in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the KYMRIAH for DLBCL. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the KYMRIAH market forecast analysis for DLBCL in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in DLBCL.

Drug Summary:

KYMRIAH (tisagenlecleucel) is a CD19-directed genetically modified autologous T-cell immunotherapy comprised of autologous T cells that are genetically modified using a lentiviral vector to encode an anti-CD19 chimeric antigen receptor (CAR). The CAR comprises a murine single-chain antibody fragment (scFv) specific for CD19, followed by a CD8 hinge and transmembrane region fused to the intracellular signaling domains for 4-1BB (CD137) and CD3 zeta.

It involves reprogramming a patient's T cells with a transgene encoding a chimeric antigen receptor (CAR) to identify and eliminate CD19-expressing malignant and normal cells. The CAR comprises a murine single-chain antibody fragment that recognizes CD19 and is fused to intracellular signaling domains from 4-1BB (CD137) and CD3 zeta. The CD3 zeta component is critical for initiating T-cell activation and antitumor activity, upon binding to CD19-expressing cells, the CAR transmits a signal to promote T-cell expansion, activation, target cell elimination, and persistence of the KYMRIAH cells.

KYMRIAH is approved for treating adult patients with R/R large B-cell lymphoma after two or more lines of systemic therapy, including DLBCL not otherwise specified, primary mediastinal large B-cell, high-grade B-cell lymphoma, and DLBCL arising from follicular lymphoma.

Scope of the Report:

The report provides insights into:

• A comprehensive product overview including the KYMRIAH description, mechanism of action, dosage and administration, research and development activities in Diffuse Large B-cell lymphoma (DLBCL).
• Elaborated details on KYMRIAH regulatory milestones and other development activities have been provided in this report.
• The report also highlights the KYMRIAH research and development activities in DLBCL across the United States, Europe and Japan.
• The report also covers the patents information with expiry timeline around KYMRIAH.
• The report contains forecasted sales of KYMRIAH for DLBCL till 2032.
• Comprehensive coverage of the late-stage emerging therapies for DLBCL.
• The report also features the SWOT analysis with analyst views for KYMRIAH in DLBCL.

Methodology:

The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.

KYMRIAH Analytical Perspective by DelveInsight

In-depth KYMRIAH Market Assessment

This report provides a detailed market assessment of KYMRIAH for Diffuse Large B-cell lymphoma (DLBCL) in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2023 to 2032.

KYMRIAH Clinical Assessment

The report provides the clinical trials information of KYMRIAH for DLBCL covering trial interventions, trial conditions, trial status, start and completion dates.

Report Highlights:

• In the coming years, the market scenario for Diffuse Large B-cell lymphoma (DLBCL) is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
• The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence KYMRIAH dominance.
• Other emerging products for DLBCL are expected to give tough market competition to KYMRIAH and launch of late-stage emerging therapies in the near future will significantly impact the market.
• A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of KYMRIAH in DLBCL.
• Our in-depth analysis of the forecasted sales data of KYMRIAH from 2023 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the KYMRIAH in DLBCL.

Key Questions:

• What is the product type, route of administration and mechanism of action of KYMRIAH?
• What is the clinical trial status of the study related to KYMRIAH in Diffuse Large B-cell lymphoma (DLBCL) and study completion date?
• What are the key collaborations, mergers and acquisitions, licensing and other activities related to the KYMRIAH development?
• What are the key designations that have been granted to KYMRIAH for DLBCL?
• What is the forecasted market scenario of KYMRIAH for DLBCL?
• What are the forecasted sales of KYMRIAH in the seven major countries, including the United States, Europe (Germany, France, Italy, Spain, and the United Kingdom), and Japan?
• What are the other emerging products available and how are these giving competition to KYMRIAH for DLBCL?
• Which are the late-stage emerging therapies under development for the treatment of DLBCL?

Table of Contents

1. Report Introduction

2. KYMRIAH Overview in DLBCL

• 2.1. Product Detail
• 2.2. Clinical Development
  • 2.2.1. Clinical studies
  • 2.2.2. Clinical trials information
  • 2.2.3. Safety and efficacy
• 2.3. Regulatory Milestone
• 2.4. Other Developmental Activities
• 2.5. Product Profile

3. Competitive Landscape (Marketed Therapies)

4. Competitive Landscape (Late-stage Emerging Therapies)

5. KYMRIAH Market Assessment

• 5.1. Market Outlook of KYMRIAH in DLBCL
• 5.2. 7MM Analysis
  • 5.2.1. Market Size of KYMRIAH in the 7MM for DLBCL
• 5.3. Country-wise Market Analysis
  • 5.3.1. Market Size of KYMRIAH in the United States for DLBCL
  • 5.3.2. Market Size of KYMRIAH in Germany for DLBCL
  • 5.3.3. Market Size of KYMRIAH in France for DLBCL
  • 5.3.4. Market Size of KYMRIAH in Italy for DLBCL
  • 5.3.5. Market Size of KYMRIAH in Spain for DLBCL
  • 5.3.6. Market Size of KYMRIAH in the United Kingdom for DLBCL
  • 5.3.7. Market Size of KYMRIAH in Japan for DLBCL

6. SWOT Analysis

7. Analysts' Views

8. Appendix

• 8.1. Bibliography
• 8.2. Report Methodology

9. DelveInsight Capabilities

10. Disclaimer

11. About DelveInsight

12. Report Purchase Options