心血管系関連の各種提携契約：契約条件・合意内容

当レポートでは、心血管系関連の各種提携契約について調査分析し、近年における各種契約の動向、大規模契約および大手製薬会社による契約の概要、契約区分・開発ステージ・技術区分・適応症区分別のディレクトリなどをまとめ、概略下記の構成でお届けいたします。

エグゼクティブサマリー

第1章 イントロダクション

第2章 心血管の契約動向

• イントロダクション
• 長期契約
• 大手製薬会社における心血管系の契約活動
• 心血管系の提携に消極的な大手製薬会社
• 契約タイプ別
• 産業分野別
• 開発段階別
• 技術タイプ別
• 症状別
• 平均契約期間

第3章 主要契約

• イントロダクション
• 主要契約：契約額別
• バイオ医薬品関連の主要契約

第4章 大手製薬会社による心血管系の契約

• イントロダクション
• 大手企業による提携取引の利用方法
• 企業プロファイル

第5章 心血管系の提携契約ディレクトリ

• イントロダクション
• 契約タイプ別
• 開発段階別
• 技術タイプ別

第6章　心血管系の契約：症状別

• イントロダクション
• 契約：治療指標別

第7章　提携リソースセンター

• オンライン提携
• 提携イベント
• 参考資料

付録

Wildwood Venturesについて

図表

Global Cardiovascular Partnering 2010-2017: Deal trends, players and financials report provides comprehensive understanding and unprecedented access to the cardiovascular partnering deals and agreements entered into by the worlds leading healthcare companies.

‘Global Cardiovascular Partnering 2010 to 2017’ provides the full collection of Cardiovascular disease deals signed between the world's pharmaceutical and biotechnology companies since 2010.

• Trends in Cardiovascular partnering deals

• Financial deal terms for headline, upfront and royalty by stage of development

• Cardiovascular partnering agreement structure

• Cardiovascular partnering contract documents

• Top Cardiovascular deals by value

• Most active Cardiovascular dealmakers

• Most of the deals included within the report occur when a licensee obtains a right or an option right to license a licensor's product or technology. More often these days these deals tend to be multi-component including both a collaborative R&D and a commercialization of outcomes element.

The report takes readers through the comprehensive Cardiovascular disease deal trends, key players and top deal values allowing the understanding of how, why and under what terms companies are currently entering Cardiovascular deals.

The report presents financial deal terms values for Cardiovascular deals, where available listing by overall headline values, upfront payments, milestones and royalties enabling readers to analyse and benchmark the value of current deals.

The initial chapters of this report provide an orientation of Cardiovascular dealmaking trends.

Chapter 1 provides an introduction to the report.

Chapter 2 provides an overview of the trends in Cardiovascular dealmaking since 2010 covering trends by year, deal type, stage of development, technology type and therapeutic indication.

Chapter 3 includes an analysis of financial deal terms covering headline value, upfront payment, milestone payments and royalty rates.

Chapter 4 provides a review of the leading Cardiovascular deals since 2010. Deals are listed by headline value. The chapter includes the top 25 most active Cardiovascular dealmakers, together with a full listing of deals to which they are a party. Where the deal has an agreement contract published at the SEC a link provides online access to the contract.

Chapter 5 provides comprehensive access to Cardiovascular deals since 2010 where a deal contract is available, providing the user with direct access to contracts as filed with the SEC regulatory authorities. Each deal title links via Weblink to an online version of the deal record contract document, providing easy access to each contract document on demand.

Chapter 6 provides a comprehensive directory of all Cardiovascular partnering deals by specific Cardiovascular target announced since 2010. The chapter is organized by specific Cardiovascular therapeutic target. Each deal title links via Weblink to an online version of the deal record and where available, the contract document, providing easy access to each contract document on demand.

In addition, a comprehensive appendix is provided with each report of all Cardiovascular partnering deals signed and announced since 2010. The appendices are organized by company A-Z, stage of development at signing, deal type (collaborative R&D, co-promotion, licensing etc) and technology type. Each deal title links via Weblink to an online version of the deal record and where available, the contract document, providing easy access to each contract document on demand.

The report also includes numerous tables and figures that illustrate the trends and activities in Cardiovascular partnering and dealmaking since 2010.

In conclusion, this report provides everything a prospective dealmaker needs to know about partnering in the research, development and commercialization of Cardiovascular technologies and products.

Report scope:

‘Global Cardiovascular Partnering 2010-2017: Deal trends, players and financials’ is intended to provide the reader with an in-depth understanding and access to cardiovascular trends and structure of deals entered into by leading companies worldwide.

‘Global Cardiovascular Partnering 2010-2017: Deal trends, players and financials’ includes:

• Trends in cardiovascular dealmaking in the biopharma industry since 2010
• Analysis of cardiovascular deal structure
• Access to headline, upfront, milestone and royalty data
• Access to over 1,000 cardiovascular deal records
• The leading cardiovascular deals by value since 2010

The report includes deals for the following indications: Abdominal aortic aneurysm, Angina, Arrhythmia, Atrial fibrillation, Long QT syndrome, Supraventricular Tachycardia, Ventricular fibrillation, Ventricular tachycardia, Atherosclerosis, Breathlessness, Cardiogenic shock, Cardiomyopathy (heart muscle disease), Chest pain, Congenital heart disease, Congestive heart failure, Coronary artery disease, Ductus arteriosus, Fatigue, Hypercholesterolemia, Hypertension, Intermittent claudication, Ischemic heart disease, Limb ischemia, Marfan's Syndrome, Myocardial Infarction, Oedema (excess fluid), Palpitations, Peripheral arterial disease, Thrombus (blood clot), Valvular heart disease, Aortic stenosis, Restenosis, Varicose veins, plus other cardiovascular indications.

In ‘Global Cardiovascular Partnering 2010-2017: Deal trends, players and financials’, the available deals are listed by:

• Company A-Z
• Headline value
• Stage of development at signing
• Deal component type
• Specific therapy target

Each deal title links via Weblink to an online version of the deal record and where available, the contract document, providing easy access to each contract document on demand.

The ‘Global Cardiovascular Partnering 2010-2017: Deal trends, players and financials’ report provides comprehensive access to available deals and contract documents for over 1,000 cardiovascular deals. Analyzing actual contract agreements allows assessment of the following:

• What are the precise rights granted or optioned?
• What is actually granted by the agreement to the partner company?
• What exclusivity is granted?
• What is the payment structure for the deal?
• How are the sales and payments audited?
• What is the deal term?
• How are the key terms of the agreement defined?
• How are IPRs handled and owned?
• Who is responsible for commercialization?
• Who is responsible for development, supply, and manufacture?
• How is confidentiality and publication managed?
• How are disputes to be resolved?
• Under what conditions can the deal be terminated?
• What happens when there is a change of ownership?
• What sublicensing and subcontracting provisions have been agreed?
• Which boilerplate clauses does the company insist upon?
• Which boilerplate clauses appear to differ from partner to partner or deal type to deal type?
• Which jurisdiction does the company insist upon for agreement law?

Benefits:

‘Global Cardiovascular Partnering 2010 to 2017’ provides the reader with the following key benefits:

• In-depth understanding of Cardiovascular deal trends since 2010

• Access Cardiovascular deal headline, upfront, milestone and royalty data

• Research hundreds of actual contracts between Cardiovascular partner companies

• Comprehensive access to over 750 links to actual Cardiovascular deals entered into by the world's biopharma companies

• Indepth review of Cardiovascular deals entered into by the top 25 most active dealmakers

• Benchmark the key deal terms companies have agreed in previous deals

• Identify key terms under which companies partner Cardiovascular opportunities

• Uncover companies actively partnering Cardiovascular opportunities

Table of Contents

Executive Summary

Chapter 1 - Introduction

Chapter 2 - Trends in Cardiovascular dealmaking

• 2.1. Introduction
• 2.2. Cardiovascular partnering over the years
• 2.3. Cardiovascular partnering by deal type
• 2.4. Cardiovascular partnering by industry sector
• 2.5. Cardiovascular partnering by stage of development
• 2.6. Cardiovascular partnering by technology type
• 2.7. Cardiovascular partnering by therapeutic indication

Chapter 3 -Financial deal terms for Cardiovascular partnering

• 3.1. Introduction
• 3.2. Disclosed financials terms for Cardiovascular partnering
• 3.3. Cardiovascular partnering headline values
• 3.4. Cardiovascular deal upfront payments
• 3.5. Cardiovascular deal milestone payments
• 3.6. Cardiovascular royalty rates

Chapter 4 - Leading Cardiovascular deals and dealmakers

• 4.1. Introduction
• 4.2. Most active in Cardiovascular partnering
• 4.3. List of most active dealmakers in Cardiovascular
• 4.4. Top Cardiovascular deals by value

Chapter 5 - Cardiovascular contract document directory

• 5.1. Introduction
• 5.2. Cardiovascular partnering deals where contract document available

Chapter 6 - Cardiovascular dealmaking by therapeutic target

• 6.1. Introduction
• 6.2. Deals by Cardiovascular therapeutic target

Appendices

• Appendix 1 - Directory of Cardiovascular deals by company A-Z 2010 to 2017
• Appendix 2 - Directory of Cardiovascular deals by deal type 2010 to 2017
• Appendix 3 - Directory of Cardiovascular deals by stage of development 2010 to 2017
• Appendix 4 - Directory of Cardiovascular deals by technology type 2010 to 2017
• Further reading on dealmaking
• Deal type definitions

About Wildwood Ventures

• Current Partnering
• Current Agreements
• Recent report titles from CurrentPartnering

Table of Figures

• Figure 1: Cardiovascular partnering since 2010
• Figure 2: Cardiovascular partnering by deal type since 2010
• Figure 3: Cardiovascular partnering by industry sector since 2010
• Figure 4: Cardiovascular partnering by stage of development since 2010
• Figure 5: Cardiovascular partnering by technology type since 2010
• Figure 6: Cardiovascular partnering by indication since 2010
• Figure 7: Cardiovascular deals with a headline value
• Figure 8: Cardiovascular deals with upfront payment values
• Figure 9: Cardiovascular deals with milestone payment
• Figure 10: Cardiovascular deals with royalty rates
• Figure 11: Active Cardiovascular dealmaking activity- 2010 to 2017
• Figure 12: Top Cardiovascular deals by value since 2010