市場調査レポート

MicroRNAおよびエキソソーム市場

MicroRNAs and Exosomes Market Report 2012

発行 SELECTBIO, Ltd. 商品コード 248301
出版日 ページ情報 英文 168 Pages
納期: 即日から翌営業日
価格
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MicroRNAおよびエキソソーム市場 MicroRNAs and Exosomes Market Report 2012
出版日: 2012年08月09日 ページ情報: 英文 168 Pages
概要

当レポートでは、MicroRNAおよびエキソソーム市場の発展動向について調査分析し、MicroRNA研究の動向、MicroRNA研究市場の規模、各種疾患クラスとの関連性、長鎖ノンコーディングRNAの可能性、各種疾患領域(癌・心疾患・神経系疾患・炎症・代謝系疾患など)におけるバイオマーカーとしてのmicroRNAシグネチャのバリデーション、エキソソームの研究動向などをまとめ、概略下記の構成でお届けいたします。

第1章 MicroRNA研究市場の分析

  • 調査範囲
  • RNA分野の区分
  • MicroRNA遺伝子・ノンコーディングRNA遺伝子
  • プライマリーマーケットサーベイ:microRNA研究の動向の評価
    • 定性的・定量的市場データ
  • MicroRNAのグラント交付メトリクス:米国
  • miRBase登録メトリクス
  • MicroRNA研究の市場規模・成長率
    • 詳細分析:同領域の区分の手段としてのmicroRNAに焦点を当てた論文
  • microRNA分野の拡張
  • 各種疾患クラスで実証されるMicroRNAアソシエーション:バイオマーカーの開発の潜在性
  • microRNAアソシエーションの翻訳上の価値
  • 長鎖ノンコーディングRNAの潜在性
  • 長鎖ノンコーディングRNAの市場動向

第2章 生理学的プロセス・疾患プロセスにおけるMicroRNA

  • 染色体変異/異常で実証されるmicroRNA
  • microRNAのエピジェネティックサイレンシング
  • microRNA発現プロファイル:血液学的悪性病変
  • microRNA発現プロファイル:固形癌
  • 癌の転帰と関連するmicroRNA(癌のパーソナライズ医療)
  • microRNA:乳癌
  • microRNA:肺癌
  • microRNA:前立腺癌
  • microRNA:膵臓癌
  • microRNA:胃腸管癌
  • 正常な筋肉発達と血管疾患
    • 血管疾患・炎症・血管新生と関連するmicroRNS
    • 心臓肥大と関連するmicroRNS
  • 糖尿病
  • CNSの正常な発展と疾患
  • 幹細胞
  • 肝臓の生理学・病理学・毒性スクリーニング

第3章 エキソソーム市場の分析

  • エキソソームの特徴
  • エキソソーム市場動向
    • 研究市場動向の定性的分析
    • 世界市場のサーベイデータ・トレンド
  • 循環バイオマーカーの新たな領域
    • 循環核酸のソース
    • 各種疾患クラスにおけるバイオマーカー候補としての血漿microRNA
    • 各種癌クラスにおける循環無細胞microRNAのシグナチャー
    • バイオマーカーの各種クラスの比較

付録:調査手法

目次

Abstract

Disease Associations and Circulating Biomarkers

This is the latest and most up-to-date Market Report from Select Biosciences addressing the microRNA and Exosomes markets as they are evolving. In this report, we focus upon the microRNA research marketplace from the perspective of the translational opportunities in these spaces. The focus of this field is moving from basic research towards the utility of associations of microRNA expression patterns in disease. In this manner, microRNA signatures may be validated as biomarkers in many disease areas - cancers, cardiovascular disease, neurological disease, inflammation, and metabolic diseases.

  • Select Biosciences has performed worldwide market tracking wherein we've analyzed end-user research trends in the microRNA as well as Exosome markets - these areas are evolving in parallel given the opportunity in the Circulating Biomarkers space and the utility of microRNAs and mRNAs to be harvested from exosomes and assayed as signatures for disease.
  • For exosomes, we've analyzed the research trends, types of downstream applications being performed as well as biomarker classes being studied currently and this is the First Market Report to Document the Market Landscape of Exosomes.

Select Biosciences has characterized the associations of microRNAs in various disease classes and presents these detailed associations as "hotspot maps" in this report. Specifically, these associations [to be interpreted as starting material for biomarker development and validation] are described for many cancer classes, cardiovascular disease, CNS disease, diabetes, inflammation, and obesity. They offer the opportunity for R&D planning efforts addressing the question of "which microRNA content needs to be addressed in a particular disease class."

This data-driven characterization of the microRNAs and Exosomes landscape is a hands-on document that can be used for competitive benchmarking, business planning, and strategy development - all the data that have been collected in this industry analysis are presented and they form the basis for the conclusions drawn throughout the market report presented in a format enabling "drag-and-drop" into business presentations/business plans - this Market Report is written and delivered to customers in PowerPoint format.

Extensive Technical and Market Analyses Presented in this Report

MicroRNA Research Market Analysis

  • Research Market Size and Growth Rate
  • Grant Funding Metrics
  • Qualitative and Quantitative Research Market Trends
    • Segmentation of Research Activities
    • Market Penetrance of Product Vendors into the microRNA Research Market
    • Unmet Needs

Association of microRNA Expression Patterns in Various Disease Classes

  • Various Types of Cancer: Breast Cancer, Lung Cancer, Prostate Cancer, Pancreatic Cancer, GI Tract Cancers, Hematological Malignancies
  • Muscular Development and Cardiovascular Disease
  • CNS Disease
  • Metabolic Disease, Diabetes
  • Stem Cells
  • Liver Disease, Liver Toxicity

Exosomes Marketplace

  • Nature and Categorization
  • Current Research Trends based on Primary Market Survey
  • Downstream Applications

Circulating Biomarkers

  • Utility of microRNA Signatures
  • microRNA Signatures in Specific Cancers Characterized in Biological Fluids to Date

Table of Contents

Description of Chapters of the Report

Chapter I. MicroRNA Research Market Analysis

  • Scope
  • Segmentation of the RNA Space
  • MicroRNA genes, non-coding RNA genes
  • Primary Market Survey to Assess microRNA Research Trends
    • Qualitative and Quantitative Market Data
  • MicroRNA Grant Funding Metrics in the US
  • miRBase Registry Metrics
  • MicroRNA Research Market Size and Growth Rate
    • Detailed Analysis of microRNA-Focused Publications as a Means to Segment the Space
  • Expansion of the microRNA Field
  • MicroRNA Association Documented in Various Disease Classes : Potential for Development into Biomarkers
  • Translational Value of microRNA Associations
  • The Potential for Long Non-coding RNAs
  • Long Non-coding RNAs Market Trends

Chapter II. MicroRNAs in Physiological and Disease Processes

  • Cancer
  • microRNAs Documented in Chromosomal Alterations/Aberrations
  • Epigenetic Silencing of microRNAs
  • microRNA Expression Profiles in Hematological Malignancies
  • microRNA Expression Profiles in Solid Tumors
  • microRNAs Associated with Outcome in Cancers [Cancer Personalized Medicine]
  • microRNAs in Breast Cancer
  • microRNAs in Lung Cancer
  • microRNAs in Prostate Cancer
  • microRNAs in Pancreatic Cancer
  • microRNAs in GI Tract Cancers
  • Normal Muscle Development and Vascular Disease
    • microRNSs Associated with Vascular Disease, Inflammation and Angiogenesis
    • microRNAs Associated with Cardiac Hypertrophy
  • Diabetes
  • CNS Normal Development and Diseases
  • Stem Cells
  • Hepatic Physiology, Pathology, and Toxicity Screening

Chapter III. Exosomes Market Analysis

  • Exosomes Characteristics
  • Exosomes Market Trends
    • Quantitative Analysis of Research Market Trends
    • Worldwide Market Survey Data and Trends Therein
  • Emerging Space of Circulating Biomarkers
    • Sources of Circulating Nucleic Acids
    • Plasma microRNAs as Candidate Biomarkers in Various Disease Classes
    • Signatures of Circulating Cell-Free microRNAs in Various Cancer Classes
    • Comparison of Various Classes of Biomarkers

Appendix. Research Methodology

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