市場調査レポート

単細胞オミクス:進展と革命

Single Cell Omics: Evolution and Revolution

発行 SELECTBIO, Ltd. 商品コード 196216
出版日 ページ情報 英文 167 Pages
納期: 即日から翌営業日
価格
本日の銀行送金レート: 1USD=101.75円で換算しております。
Back to Top
単細胞オミクス:進展と革命 Single Cell Omics: Evolution and Revolution
出版日: 2011年05月27日 ページ情報: 英文 167 Pages
概要

当レポートでは、単細胞オミクスの主な技術と応用分野、アンメットニーズと動向などをまとめ、概略下記の構成でお届けいたします。

第1章 エグゼクティブサマリー

第2章 歴史的展望

  • 単細胞
  • オミクス
  • オミクスと少数細胞
  • オミクスと単細胞

第3章 細胞の不均一性

  • イントロダクション
  • 不均一性の例
    • RNA干渉
    • C.Elegansにおける遺伝子発現プロファイル
  • 不均一性のその他の事例

第4章 フロントエンド技術

  • 技術概要
  • フロントエンドのイントロダクション
  • 調査項目
  • FACS調整細胞ソーティング
  • 磁気ビーズ調整細胞ソーティング
  • 顕微鏡的キャプチャ/マイクロマニピュレーション
  • レーザーキャプチャ顕微解剖

第5章 バックエンド技術

  • イントロダクション
  • 最新動向
  • 技術概要
  • 調査項目
  • 最新事例
  • 将来の方向性

第6章 フロントエンドとバックエンドの橋渡し

  • イントロダクション
  • 第1世代プラットフォームの事例
  • 第2世代プラットフォームの事例
  • 調査項目

第7章 新興の応用

  • イントロダクション
  • 文献分析
  • 確立/新興の応用
    • 幹細胞
    • 免疫学
    • 神経生物学
  • 新興の応用分野
    • 循環腫瘍細胞
    • システム生物学

第8章 市場モデル

  • 方法
  • 文献分析
  • 調査項目
  • 市場モデル

第9章 競合環境

  • イントロダクション
  • 循環腫瘍細胞/希少細胞
  • DNAシーケンシング
  • マイクロ流体
  • 顕微鏡キャプチャ 他
目次

The single cell Omics revolution is the potential transformation of cellular heterogeneity from a source of noise to a source of new, as yet hidden discoveries. No longer will the variability from one cell to the next confound researchers and force them to average results into irrelevance. Researchers may find, in fact, that this variability is critical for cells to respond to and interact with their environments. But even without the complete revolution, single cell Omics offer significant evolutionary advances in fields of biology and medicine that are already based on single cell analysis, such as immunology, neurobiology, stem cell biology, circulating tumor cells and preimplantation genetic diagnosis. Moreover, the ongoing evolution of single cell Omics technologies provides improvements in sensitivity and throughput that will enable researchers to generate more data from smaller numbers of cells, which can be enabling in cases of precious samples. The result of this (r)evolution is a market for Omics technologies that is projected to grow from $60 million in sales in 2010 to $525 million in 2016, according to Single Cell Omics 2011, a new report published by Select Biosciences and written by BioPerspectives.

Survival of the fittest requires a detailed understanding of this emerging market. Single Cell Omics 2011 explains the key technologies, applications, unmet needs and trends. The 167-page report includes an Internet survey administered to a large stratified database; analyses of front-end separation technologies, back-end Omics technologies and integrated platforms to bridge the gap; profiles of 30 companies; and a quantitative market model segmented by technologies. In addition, the report comes with a reprint of the Trends in Biotechnology cover article written by two of the report authors. Moreover, the report also comes with one hour of consulting (in the form of a conference call) with report authors Dr. Bodovitz, Principal of BioPerspectives or Antje Plaschke-Schluetter, Head of Application at Molecular Machines & Industries AG. To order a copy of the report and increase your fitness, please click here.

Table of Contents

Chapter 1: Executive Summary

  • Introduction
  • Cellular Heterogeneity
  • Front-End Isolation of Single Cells
  • Back-End Isolation of Single Cells
  • Bridging Front- and Back-End
  • Applications
  • Competitive Environment
  • Trends in Usage
  • Prediction of Market Inflections
  • Market Model

Chapter 2: Historical Perspective

  • Single Cells
  • Omics
  • Omics and Small Numbers of Cells
  • Omics and Single Cells

Chapter 3: Cellular Heterogeneity

  • Introduction
  • Specific Examples of Heterogeneity
    • RNA Interference
    • Gene Expression Profiles in C. Elegans
  • More Examples of Heterogeneity
  • Root Cause
  • Survey Question
  • Significance
  • From Noise to Discoveries
  • The Trend
  • Survey Question

Chapter 4: Front-End Technologies

  • Overview of Technologies
  • Introduction to the Front-End
  • Survey Question
  • FACS-Mediated Cell Sorting
    • Introduction
    • Competition
  • Magnetic Bead-Mediated Cell Sorting
    • Introduction
    • Competition
  • Microscopic Capture/Micromanipulation
    • Introduction
    • Competition
  • Laser Capture Microdissection
    • Introduction
    • Competition

Chapter 5: Back-End Technologies

  • Introduction
  • State-of-the-Art
  • Technology Overview
  • Survey Question
  • Examples of State of the Art
    • Genomics
    • Survey Question
    • Metabolomics
    • Survey Questions
    • Microfluidic Interface with Mass Spectrometry
  • Future Directions
    • Evolution
    • Revolution

Chapter 6: Bridging the Front- and Back-Ends

  • Introduction
  • Examples of First-Generation Platforms
    • Beckman Coulter
    • MMI
  • Examples of Second-Generation Platforms
    • Silicon Biosystems
    • Microcavity Array
    • Single Cell Microarray
  • Survey Question

Chapter 7: Emerging Applications

  • Introduction
  • Literature Analysis
    • Established
    • Preimplantation Genetic Diagnosis/Screening
  • Established/Emerging
    • Stem Cells
    • Immunology
    • Neurobiology
  • Emerging
    • Cancer
    • Circulating Tumor Cells
      • Introduction
      • Workflow 1
      • Workflow 2
      • Workflow 3
      • Workflow 4
      • Workflow 5
  • Systems Biology

Chapter 8: Market Model

  • Methodology
    • 2010
    • Growth
  • Literature Analysis
  • Survey Questions
  • Market Model
    • Overall Technology Markets
    • Top-Down Analysis for 2010
    • Growth Projections

Chapter 9: Competitive Environment

  • Introduction
  • Circulating Tumor Cells/Rare Cells
    • Adnagen
    • Biocept
    • Cytotrack
    • Rarecells
    • Silicon Biosystems
    • Veridex
  • DNA Sequencing
    • IBM
    • IonTorrent
    • Oxford Nanopore Technologies
    • Pacific Biosciences
  • Microfluidics
    • BioNanomatrix
    • Cyntellect
    • Fluidigm
    • Fluxion Biosciences
    • IntegenX
    • Mathies Lab
    • Microfluidic ChipShop
    • RainDance Technologies
  • Microscopic Capture
    • Eppendorf
    • Hacker Instruments
    • Ibidi
    • Leica Microsystems
    • MMI
    • Narishige
    • Zeiss
  • Multifaceted
    • Life Technologies
    • Miltenyi Biotec
    • Roche Applied Science
    • TATAA Biocenter
  • Outside-the-Box
    • LBNL
    • UC Irvine
  • Preimplantation Genetic Diagnosis
    • Reprogenetics

Appendix: Methodology

  • Author Credentials
  • Sources
  • Market Model
  • Literature Analysis
  • Internet Survey
    • Background Question 1
    • Background Question 2
    • Background Question 3
    • Background Question 4
Back to Top