市場調査レポート
商品コード
998804

未分化リンパ腫キナーゼ (ALK) 阻害薬の世界市場 - 医薬品販売、価格、臨床試験の考察:2026年

Global Anaplastic Lymphoma Kinase ALK Inhibitors Market, Drug Sales, Price & Clinical Trials Insight 2026

出版日: | 発行: KuicK Research | ページ情報: 英文 190 Pages | 納期: 即日から翌営業日

価格
価格表記: USDを日本円(税抜)に換算
本日の銀行送金レート: 1USD=148.88円

ご注意: DRM (デジタル著作権管理システム) 付PDFになります。制限内容は、上記ライセンスの[詳細]アイコンをクリックしてご確認ください。

未分化リンパ腫キナーゼ (ALK) 阻害薬の世界市場 - 医薬品販売、価格、臨床試験の考察:2026年
出版日: 2021年04月07日
発行: KuicK Research
ページ情報: 英文 190 Pages
納期: 即日から翌営業日
  • 全表示
  • 概要
  • 図表
  • 目次
概要

過去数十年の科学技術の進歩により、医薬品開発プロセスで利用できる、いくつかの潜在的な標的が特定されました。未分化リンパ腫キナーゼ (ALK) 遺伝子の特性評価と、ALK陽性がんの発生と進行におけるそれらの役割は、がん治療薬市場を変革しました。研究者による広範な研究活動が、チロシン受容体キナーゼのクラスに属し、がんの管理に使用される、新興の未分化リンパ腫キナーゼ (ALK) 阻害薬の開発につながりました。

当レポートでは、世界の未分化リンパ腫キナーゼ (ALK) 阻害薬市場について調査分析し、市場機会、承認薬、市場の販売考察、特許、臨床試験の考察などについて、体系的な情報を提供しています。

目次

第1章 未分化リンパ腫キナーゼ (ALK) 阻害薬のイントロダクション

  • 概要
  • 開発の歴史

第2章 がん治療薬としての未分化リンパ腫キナーゼ (ALK) 阻害薬

  • がん治療における未分化リンパ腫キナーゼ (ALK) 阻害薬の必要性
  • ALK - がん治療における潜在的な標的
  • 作用機序

第3章 肺がんにおける未分化リンパ腫キナーゼ (ALK) 阻害薬

  • 肺がんにおける未分化リンパ腫キナーゼ (ALK) 阻害薬の役割
  • 進行中の研究開発

第4章 神経芽腫における未分化リンパ腫キナーゼ (ALK) 阻害薬

  • 神経芽腫における未分化リンパ腫キナーゼ (ALK) 阻害薬の役割
  • 進行中の臨床研究

第5章 リンパ腫における未分化リンパ腫キナーゼ (ALK) 阻害薬

  • リンパ腫におけるALKの役割
  • 進行中の臨床研究

第6章 その他のがんにおける未分化リンパ腫キナーゼ (ALK) 阻害薬

  • 大腸がんにおける未分化リンパ腫キナーゼ (ALK) 阻害薬
  • 腎細胞がんにおけるALK
  • 炎症性筋線維芽細胞腫瘍における未分化リンパ腫キナーゼ (ALK) 阻害薬

第7章 Crizotinib (Xalkori) - 臨床・商業的考察

  • 概要
  • 特許・譲受人
  • 投与量・価格分析
  • 販売分析

第8章 Certinib (Zykadia) - 臨床・商業的考察

  • 概要
  • 特許・譲受人
  • 投与量・価格分析

第9章 Alectinib (Alecensa) - 臨床・商業的考察

  • 概要
  • 特許・譲受人
  • 投与量・価格分析
  • 販売分析

第10章 Brigatinib (Alunbrig) - 臨床・商業的考察

  • 概要
  • 特許情報
  • 投与量・価格分析
  • 販売分析

第11章 Lorlatinib (Lorbrena) - 臨床・商業的考察

  • 概要
  • 投与量・特許・価格分析
  • 販売分析

第12章 がんにおける新興の未分化リンパ腫キナーゼ (ALK) 阻害薬

  • Ensartinib
  • Entrectinib (RXDX-101)
  • TPX-0131
  • TQ-B3139
  • Belizatinib (TSR-011)
  • CEP-37440
  • Alkotinib

第13章 未分化リンパ腫キナーゼ (ALK) 阻害薬市場分析 - 臨床試験の考察

  • フェーズ別
  • 企業別
  • 国別
  • 患者セグメント別

第14章 未分化リンパ腫キナーゼ (ALK) 阻害薬市場

  • 現在の市場シナリオ
  • 世界・地域別の市場分析

第15章 未分化リンパ腫キナーゼ (ALK) 阻害薬市場:製品別

  • 第一世代未分化リンパ腫キナーゼ (ALK) 阻害薬
  • 第二世代未分化リンパ腫キナーゼ (ALK) 阻害薬
  • 第三世代未分化リンパ腫キナーゼ (ALK) 阻害薬

第16章 未分化リンパ腫キナーゼ (ALK) 阻害薬の臨床試験の考察

  • 研究
  • 前臨床
  • フェーズI
  • フェーズI/II
  • フェーズII
  • フェーズIII

第17章 市販の未分化リンパ腫キナーゼ (ALK) 阻害薬の臨床考察

  • ALUNBRIG
  • Lorbrena/Lorviqua
  • Alecensa
  • Jikadia/ Zykadia
  • Xalkori

第18章 未分化リンパ腫キナーゼ (ALK) 阻害薬 - 進行中の研究開発

第19章 未分化リンパ腫キナーゼ (ALK) 阻害薬市場の将来の見通し

  • 未分化リンパ腫キナーゼ (ALK) 阻害薬の将来予測
  • 未分化リンパ腫キナーゼ (ALK) 阻害薬の将来の市場機会

第20章 未分化リンパ腫キナーゼ (ALK) 阻害薬の市場力学

  • 未分化リンパ腫キナーゼ (ALK) 阻害薬市場の好ましいパラメーター
  • 未分化リンパ腫キナーゼ (ALK) 阻害薬市場への障壁

第21章 競合情勢

  • Astellas Pharma
  • AstraZeneca
  • Betta Pharmaceuticals
  • GlaxoSmithKline
  • Merck
  • Novartis
  • Pfizer
  • Roche
  • Takeda Pharmaceuticals
  • Turning Point Therapeutics
図表

List of Figures

  • Figure 1-1: History of Anaplastic Lymphoma Kinase Inhibitors
  • Figure 2-1: Frequency of ALK Rearrangements by Cancer
  • Figure 2-2: Structure of Anaplastic Lymphoma Kinase (ALK) Gene
  • Figure 2-3: ALK - Potential Target in Cancer Therapy
  • Figure 2-4: Anaplastic Lymphoma Kinase Signaling Pathway
  • Figure 2-5: Crizotinib - Mechanism of Action
  • Figure 2-6: Alectinib - Mechanism of Action
  • Figure 3-1: Role of ALK Inhibitors in NSCLC
  • Figure 3-2: Approved ALK Inhibitors for NSCLC
  • Figure 3-3: Ongoing Trials with Combination Therapy in ALK-Rearranged NSCLCs
  • Figure 4-1: ALK Protein Structure & Mutations Found in Neuroblastoma
  • Figure 4-2: Clinical trials Evaluating ALK Inhibitors in Neuroblastoma
  • Figure 5-1: Clinical trials Evaluating ALK Inhibitors in Lyphoma
  • Figure 6-1: ALK Fusions in Renal Cell Carcinoma
  • Figure 7-1: Xalkori - FDA Approval by Indication
  • Figure 7-2: Xalkori - FDA Approval by Region
  • Figure 7-3: US - Sugen's Xalkori Patent Issue & Expiration Year
  • Figure 7-4: US - Pfizer's Xalkori Patent Issue & Expiration Year
  • Figure 7-5: US - Agouron's Xalkori Patent Issue & Expiration Year
  • Figure 7-6: US - Price for 60 Capsule Supply & Price Per Unit of Xalkori Oral Capsule (US$), March'2021
  • Figure 7-7: UK - Price for 60 Capsule Supply & Price Per Unit of Xalkori Oral Capsule (US$/GBP), March'2021
  • Figure 7-8: Xalkori - Recommended & Reduced Daily Dose (mg)
  • Figure 7-9: Global - Xalkori Annual Sales (US$ Million), 2017 - 2020
  • Figure 7-10: US - Xalkori Annual Sales (US$ Million), 2017 - 2020
  • Figure 7-11: Global - Xalkori Annual Sales by Region (US$ Million), 2020
  • Figure 7-12: Global - Xalkori Annual Sales by Region (%), 2020
  • Figure 7-13: Global - Xalkori Quarterly Sales (US$ Million), 2019 & 2020
  • Figure 7-14: US - Xalkori Quarterly Sales (US$ Million), 2020
  • Figure 7-15: Europe - Xalkori Quarterly Sales (US$ Million), 2020
  • Figure 8-1: Zykadia - FDA Approval by Indication
  • Figure 8-2: Zykadia - FDA Approval Year by Region
  • Figure 8-3: US - Number of Zykadia Patents by Assignee
  • Figure 8-4: US - Novartis's Zykadia Patent Issue & Expiration Year
  • Figure 8-5: US - Rigel's Zykadia Patent Issue & Expiration Year
  • Figure 8-6: US - IRM's Zykadia Patent Issue & Expiration Year
  • Figure 8-7: US - Price for 84 Tablets Supply & Price Per Unit of Zykadia Oral Tablet (US$), Mrch'2021
  • Figure 8-8: UK - Price for 84 Tablets Supply & Price Per Unit of Zykadia Oral Tablet (US$/GBP), March'2021
  • Figure 8-9: Zykadia - Recommended & Reduced Dose for NSCLC Treatment (mg per day)
  • Figure 9-1: Alsensa - FDA Approval by Indication
  • Figure 9-2: Alsensa - FDA Approval by Region
  • Figure 9-3: US - Alecensa Patent Issue & Expiration Year
  • Figure 9-4: US - Price for 240 Tablet Supply & Price Per Unit of Alecensa Oral Tablet (US$), March'2021
  • Figure 9-5: UK - Price for 224 Tablet Supply & Price Per Unit of Alecensa Oral Tablet (US$/GBP), March'2021
  • Figure 9-6: Alecensa - Recommended & Reduced Dose for NSCLC Treatment (mg per day)
  • Figure 9-7: Global - Alecensa Annual Sales (US$/CHF Million), 2017 - 2020
  • Figure 9-8: US - Alecensa Annual Sales (US$/CHF Million), 2017 - 2020
  • Figure 9-9: Europe - Alecensa Annual Sales (US$/CHF Million), 2018 - 2020
  • Figure 9-10: Japan - Alecensa Annual Sales (US$/CHF Million), 2017 - 2020
  • Figure 9-11: Global - Alecensa Annual Sales by Region (US$/CHF Million), 2020
  • Figure 9-12: Global - Alecensa Annual Sales by Region (%), 2020
  • Figure 9-13: Global - Alecensa Quarterly Sales (US$/CHF Million), 2019
  • Figure 9-14: Global - Alecensa Quarterly Sales (US$/CHF Million), 2020
  • Figure 9-15: US - Alecensa Quarterly Sales (US$/CHF Million), 2020
  • Figure 9-16: Europe - Alecensa Quarterly Sales (US$/CHF Million), 2020
  • Figure 9-17: Japan - Alecensa Quarterly Sales (US$/CHF Million), 2020
  • Figure 10-1: Alunbrig - FDA Approval by Indication
  • Figure 10-2: Alunbrig - FDA Approval Year by Region
  • Figure 10-3: Alunbirg - Patent Issue & Expiration Year
  • Figure 10-4: US - Price for 30 Tablets & Price Per Unit of 30mg Alunbirg Tablet (US$), March'2021
  • Figure 10-5: US - Price for Various Supplies of 90 mg Alunbirg Tablet (US$), March'2021
  • Figure 10-6: US - Price for 30 Tablets & Price Per Unit of 180mg Alunbirg Tablet (US$), March'2021
  • Figure 10-7: US - Price for 30 Tablets & Price Per Unit of 90-180mg Alunbirg Tablet (US$), March'2021
  • Figure 10-8: UK - Price for Various Supplies of Alunbirg Oral Tablet of 30mg (US$/GBP), March'2021
  • Figure 10-9: UK - Price for Various Supplies of Alunbirg Oral Tablet of 90mg (US$/GBP), March'2021
  • Figure 10-10: UK - Price for 28 Tablets & Price Per Unit Tablet of Alunbirg 180mg (US$/GBP), March'2021
  • Figure 10-11: UK - Price for 28 Tablets & Price Per Unit Tablet of Alunbirg 90mg-180mg (US$/GBP), March'2021
  • Figure 10-12: Alunbirg - Recommended & Reduced Dose (mg)
  • Figure 10-13: Global - Alunbrig Annual Sales (US$/JPY Million), 2018 - 2020
  • Figure 10-14: Global - Alunbrig Quarterly Sales (US$/JPY Million), 2019
  • Figure 10-15: Global - Alunbrig Quarterly Sales (US$/JPY Million), 2020
  • Figure 10-16: Global - Alunbrig Annual Sales by Region (US$/JPY Million), 2020
  • Figure 10-17: Global - Alunbrig Annual Sales by Region (%), 2020
  • Figure 10-18: US - Alunbrig Quarterly Sales (US$/JPY Million), 2020
  • Figure 11-1: Lorbrena - FDA Approval by Indication
  • Figure 11-2: Lorbrena - FDA Approval Year by Region
  • Figure 11-3: US - Lorbrena Patent Issue & Expiration Year
  • Figure 11-4: US - Price for 30 Tablet Supply & Price Per Unit of 25mg Lorbrena Oral Tablet (US$), March'2021
  • Figure 11-5: US - Price for 30 Tablet Supply & Price Per Unit of 100 mg Lorbrena Oral Tablet (US$), March'2021
  • Figure 11-6: UK - Price for 90 Tablets Supply & Price Per Unit of Lorbrena Oral Tablet of 25mg (US$/GBP), March'2021
  • Figure 11-7: UK - Price for 120 Tablets Supply & Price Per Unit of Lorbrena Oral Tablet of 25mg (US$/GBP), March'2021
  • Figure 11-8: UK - Price for 30 Tablets Supply & Price Per Unit of Lorbrena Oral Tablet of 100mg (US$/GBP), March'2021
  • Figure 11-9: Lorbrena - Recommended & Reduced Dose for NSCLC Treatment (mg per day), March'2021
  • Figure 11-10: Global - Lorbrena Annual Sales (US$ Million), 2019 & 2020
  • Figure 11-11: US - Lorbrena Annual Sales (US$ Million), 2019 & 2020
  • Figure 11-12: Europe - Lorbrena Annual Sales (US$ Million), 2019 & 2020
  • Figure 11-13: ROW - Lorbrena Annual Sales (US$ Million), 2019 & 2020
  • Figure 11-14: Global - Lorbrena Annual Sales by Region (US$ Million), 2020
  • Figure 11-15: Global - Lorbrena Annual Sales by Region (US$ Million), 2020
  • Figure 12-1: Ensartinib - Mechanism of Action
  • Figure 12-2: Clinical Trials using Ensartinib
  • Figure 13-1: Global - ALK Inhibitor Clinical Trials by Phase (Number of Drugs), 2021 Till 2026
  • Figure 13-2: Global - ALK Inhibitor Clinical Trials by Company (Number of Drugs), 2021 Till 2026
  • Figure 13-3: Global - ALK Inhibitor Clinical Trials by Country (Number of Trials), 2021 Till 2026
  • Figure 13-4: Global - ALK Inhibitor Clinical Trials by Patient Segment (Number of Trials), 2021 Till 2026
  • Figure 13-5: ALK Inhibitor Clinical Trials by Region
  • Figure 13-6: North America - ALK Inhibitor Clinical Trial by Region
  • Figure 14-1: Lung Cancer Incidences by Region (Million), 2020 & 2040
  • Figure 14-2: Global - Anaplastic Lymphoma Kinase Inhibitors Market Size (US$ Billion), 2017-2020
  • Figure 14-3: Global - Anaplastic Lymphoma Kinase Inhibitors Market Size (US$ Billion), 2021-2026
  • Figure 14-4: US - Anaplastic Lymphoma Kinase Inhibitors Market Size (US$ Million), 2017-2020
  • Figure 14-5: US - Anaplastic Lymphoma Kinase Inhibitors Market Size (US$ Million), 2019-2026
  • Figure 14-6: Europe - Anaplastic Lymphoma Kinase Inhibitors Market Size (US$ Million), 2020-2026
  • Figure 15-1: Global - First Generation ALK Inhibitor Market Size (US$ Million), 2017-2020
  • Figure 15-2: Global - First Generation ALK Inhibitor Market Size (US$ Million), 2021-2026
  • Figure 15-3: ALK Inhibitor Drug Market by Product (%), 2020
  • Figure 15-4: ALK Inhibitor Drug Market by Product (%), 2026
  • Figure 15-5: US - First Generation ALK Inhibitor Market Size (US$ Million), 2017 - 2020
  • Figure 15-6: US - First Generation ALK Inhibitor Market Size (US$ Million), 2021-2026
  • Figure 15-7: Europe - First Generation ALK Inhibitor Market Size (US$ Million), 2017 - 2020
  • Figure 15-8: Europe - First Generation ALK Inhibitor Market Size (US$ Million), 2021-2026
  • Figure 15-9: First Generation ALK Inhibitor - Market Size by Region (%), 2020
  • Figure 15-10: Global - Second Generation ALK Inhibitor Market Size (US$ Million), 2018-2020
  • Figure 15-11: Global - Second Generation ALK Inhibitor Market Size (US$ Million), 2021-2026
  • Figure 15-12: Second Generation ALK Inhibitor - Market Size by Product (%), 2020
  • Figure 15-13: US - Second Generation ALK Inhibitor Market Size (US$ Million), 2018-2020
  • Figure 15-14: US - Second Generation ALK Inhibitor Market Size (US$ Million), 2021-2026
  • Figure 15-15: Second Generation ALK Inhibitor - Market Size by Region (%), 2020
  • Figure 15-16: Second Generation ALK Inhibitor - Market Size by Region (%), 2026
  • Figure 15-17: US - Alecensa Market Size (US$ Million), 2017 - 2020
  • Figure 15-18: US - Alecensa Market Size (US$ Million), 2021 - 2026
  • Figure 15-19: Europe - Alecensa Market Size (US$ Million), 2018 - 2020
  • Figure 15-20: Europe - Alecensa Market Size (US$ Million), 2021 - 2026
  • Figure 15-21: Alecensa - Market Size by Region (%), 2020
  • Figure 15-22: Global - Lorlatinib Market Size (US$ Million), 2019 & 2020
  • Figure 15-23: Global - Third Generation ALK Inhibitor Market Size (US$ Million), 2021-2026
  • Figure 15-24: ALK Inhibitor Drug Market by Product (%), 2020
  • Figure 15-25: US - Lorlatinib Market Size (US$ Million), 2019 & 2020
  • Figure 15-26: US - Third Generation ALK Inhibitor Market Size (US$ Million), 2021-2026
  • Figure 15-27: Europe - Lorlatinib Market Size (US$ Million), 2019 & 2020
  • Figure 15-28: Europe - Third Generation ALK Inhibitor Market Size (US$ Million), 2021-2026
  • Figure 18-1: Lorbrena - Risk of Tumor Progression (%)
  • Figure 18-2: Risk of Tumor Progression by Product (%)
  • Figure 19-1: Global - Tyrosine Kinase Inhibitor Market Size (US$ Billion), 2017-2020
  • Figure 19-2: Global - Tyrosine Kinase Inhibitor Market Size (US$ Billion), 2021-2026
  • Figure 19-3: Global - Anaplastic Lymphoma Kinase Inhibitor Market Size (US$ Billion), 2017-2020
  • Figure 19-4: Tyrosine Kinase Inhibitor Market by Type (%), 2020
  • Figure 19-5: Global - ALK Inhibitor Market Opportunity by 15% Tyrosine Kinase Inhibitor Market (US$ Billion), 2021-2026
  • Figure 19-6: Global - ALK Inhibitor Market Opportunity by 20% Tyrosine Kinase Inhibitor Market (US$ Billion), 2021-2026
  • Figure 19-7: Global - ALK Inhibitor Market Opportunity by 25% Tyrosine Kinase Inhibitor Market (US$ Billion), 2021-2026
  • Figure 19-8: Global - ALK Inhibitor Market Opportunity by 25% Tyrosine Kinase Inhibitor Market (US$ Billion), 2021-2026
  • Figure 19-9: Global - Tagrisso Market Size (US$ Billion), 2017-2020
  • Figure 19-10: Global - Alectinib Market Size (US$ Billion), 2021-2026
  • Figure 20-1: ALK Inhibitors Drug Market Favorable Parameters
  • Figure 20-2: Cancer Incidences by Region (Million), 2020 & 2040
  • Figure 20-3: Cancer Deaths by Region (Million), 2020 & 2040
  • Figure 20-4: Alunbrig - Average Cost of Daily, Monthly & Annual Cost of Treatment (US$), March'2021
  • Figure 20-5: Lorbrena - Average Cost of Daily, Monthly & Annual Cost of Treatment (US$), March'2021
  • Figure 20-6: Barriers to ALK Inhibitor Drug Market
目次

“Global Anaplastic Lymphoma Kinase ALK Inhibitors Market & Clinical Trials Insight 2026” Report Highlights:

  • Global ALK Inhibitors Market Opportunity: > USD 5 Billion
  • US Dominates Global ALK Inhibitors Market Sales: >30%
  • Approved ALK Inhibitors: 5 Drugs
  • Global & Regional ALK Inhibitors Market Sales Insights (2017-2020)
  • Global & Regional ALK Inhibitors Market Opportunity (2021-2026)
  • Approved ALK Inhibitors Dosage, Patent, Price & Sales Insights
  • Global Clinical Trials Insight By Company, Indication & Phase

The progress made by science and technology in last few decades has led to identification of several potential targets which can be utilized in the drug development process. The characterization of anaplastic lymphoma kinase (ALK) gene and their role in the development and progression of ALK positive cancer has transformed the cancer therapeutics market. The extensive research activities by the researchers have led to the development of novel anaplastic lymphoma kinase inhibitors which belongs to the class of tyrosine receptor kinase and are used in the management of cancer.

Till now, multiple anaplastic lymphoma kinase inhibitors have been approved by the regulatory authorities and several others are present in clinical pipeline which are expected to enter the market in next few years. The advent of these drugs in the market has overcome the limitations of conventional therapies such as chemotherapy and radiotherapy. The high target ability and specificity of these inhibitors towards the cancer cells has enhanced the survival rates of cancer patients and also improved the quality of life of patients.

Since the approval of first generation anaplastic lymphoma kinase inhibitor in the management of non-small cell lung cancer, researchers have indulge in research activities for the development of next generation inhibitors which can overcome the limitations and can efficiently cross the blood brain barrier for enhanced efficacy. Apart from this, several clinical trials are ongoing to evaluate the efficacy of these drugs in combination with other chemotherapeutic drugs and immune checkpoint inhibitors. The combinational therapy will increase the efficacy of the drug which can better combat the complexity of the cancer.

The global anaplastic lymphoma kinase inhibitor market is going to witness high growth during the forecast period which is mainly attributed to the rise in prevalence of anaplastic lymphoma kinase positive cancers and high research and development activities in this sector. The rates at which conventional therapies are failing will further possess unmet need for the development of novel target therapies which will also drive the growth of the market. In addition to this, the robust clinical pipeline and their increasing application in different cancers will drive the market in coming years.

Despite several advantages of anaplastic lymphoma kinase inhibitors in management of cancer, there are several factors which restrains the growth of market. The resistance to the drugs during 1-2 year of the therapy is one of the limiting factors which will act as a barrier to the market. Moreover, the high cost associated with the drug will also limit the availability of the drug and increases the financial toxicity on the patient and their families.

Currently, US holds the top position in the global market and is expected to maintain its position over the forecast period mainly due to the presence of large pharmaceutical sector which actively invest in research and development activities as well as increasing funding by the government to promote research and development. Apart from this, other regions such Europe, Asia-Pacific and Japan are also expanding their markets to secure their position in the global market. The global anaplastic lymphoma kinase inhibitor market is going to witness high growth rate and is expected to double in next 5 years. Furthermore, the market will be flourished with next generation ALK inhibitors as well as several combintional therapies in wide range of cancers including neuroblastoma, lymphoma and colorectal cancer.

The report “Global Anaplastic Lymphoma Kinase ALK Inhibitors Market & Clinical Trials Insight 2026” includes information about the patent expiration, dosage, price, sales and mechanism of currently approved anaplastic lymphoma kinase inhibitors. In addition to this, several emerging ALK inhibitors along with their clinical trials are also provided in the report.

Table of Contents

1. Introduction to Anaplastic Lymphoma Kinase (ALK) Inhibitors

  • 1.1. Overview
  • 1.2. History of Development

2. ALK Inhibitors as Cancer Therapeutics

  • 2.1. Need of ALK Inhibitors in Cancer Therapy
  • 2.2. ALK - Potential Target in Cancer Therapy
  • 2.3. Mechanism of Action

3. ALK Inhibitors in Lung Cancer

  • 3.1. Role of ALK Inhibitors in Lung Cancer
  • 3.2. On Going Research & Development

4. ALK Inhibitors in Neuroblastoma

  • 4.1. Role of ALK Inhibitor in Neuroblastoma
  • 4.2. On Going Clinical Research

5. ALK Inhibitors in Lymphoma

  • 5.1. Role of ALK in Lymphoma
  • 5.2. On Going Clinical Research

6. ALK Inhibitors in Other Cancers

  • 6.1. ALK Inhibitor in Colorectal Cancer
  • 6.2. ALK in Renal Cell Carcinoma
  • 6.3. ALK Inhibitor in Inflammatory Myofibroblastic Tumor

7. Crizotinib (Xalkori) - Clinical & Commercial Insight

  • 7.1. Overview
  • 7.2. Patents & Assignees
  • 7.3. Dosage & Price Analysis
  • 7.4. Sales Analysis

8. Certinib (Zykadia) - Clinical & Commercial Insight

  • 8.1. Overview
  • 8.2. Patents & Assignees
  • 8.3. Dosage & Price Analysis

9. Alectinib (Alecensa) - Clinical & Commercial Insight

  • 9.1. Overview
  • 9.2. Patents & Assignee
  • 9.3. Dosage & Price Analysis
  • 9.4. Sales Analysis

10. Brigatinib (Alunbrig) - Clinical & Commercial Insight

  • 10.1. Overview
  • 10.2. Patent Information
  • 10.3. Dosage & Price Analysis
  • 10.4. Sales Analysis

11. Lorlatinib (Lorbrena) - Clinical & Commercial Insight

  • 11.1. Overview
  • 11.2. Dosage, Patent & Price Analysis
  • 11.3. Sales Analysis

12. Emerging Novel ALK Inhibitors in Cancer

  • 12.1. Ensartinib
  • 12.2. Entrectinib (RXDX-101)
  • 12.3. TPX-0131
  • 12.4. TQ-B3139
  • 12.5. Belizatinib (TSR-011)
  • 12.6. CEP-37440
  • 12.7. Alkotinib

13. ALK Inhibitor Market Analysis - Clinical Trial Insight

  • 13.1. By Phase
  • 13.2. By Company
  • 13.3. By Country
  • 13.4. By Patient Segment

14. ALK Inhibitors Drug Market

  • 14.1. Current Market Scenario
  • 14.2. Global & Regional Market Analysis

15. ALK Inhibitor Drug Market by Product

  • 15.1. First Generation ALK Inhibitor
  • 15.2. Second Generation ALK Inhibitor
  • 15.3. Third Generation ALK Inhibitor

16. Anaplastic Lymphoma Kinase (ALK) Inhibitors Clinical Trials Insight

  • 16.1. Research
  • 16.2. Preclinical
  • 16.3. Phase-I
  • 16.4. Phase-I/II
  • 16.5. Phase-II
  • 16.6. Phase-III

17. Marketed Anaplastic Lymphoma Kinase (ALK) Inhibitors Clinical Insight

  • 17.1. ALUNBRIG
  • 17.2. Lorbrena/Lorviqua
  • 17.3. Alecensa
  • 17.4. Jikadia/ Zykadia
  • 17.5. Xalkori

18. ALK Inhibitor - On Going Research & Development

  • 18.1. Lorbrena Overcomes Xalkori as Front-Line Therapy in NSCLC
  • 18.2. Comparable Time to Treatment Deterioration of Lorlatinib & Crizotinib in Patients with NSCLC
  • 18.3. FDA Approved CDx Assay for Lorlatinib in ALK Positive NSCLC
  • 18.4. TPX-0131 Overcomes ALK Mutations in Preclinical Models

19. ALK Inhibitor Drug Market Future Prospects

  • 19.1. ALK Inhibitor Future Forecast
  • 19.2. Future Market Opportunity of ALK Inhibitor

20. ALK Inhibitor Drug Market Dynamics

  • 20.1. ALK Inhibitor Drug Market Favorable Parameters
  • 20.2. Barriers to ALK Inhibitor Drug Market

21. Competitive Landscape

  • 21.1. Astellas Pharma
  • 21.2. AstraZeneca
  • 21.3. Betta Pharmaceuticals
  • 21.4. GlaxoSmithKline
  • 21.5. Merck
  • 21.6. Novartis
  • 21.7. Pfizer
  • 21.8. Roche
  • 21.9. Takeda Pharmaceuticals
  • 21.10. Turning Point Therapeutics