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市場調査レポート

オーソバイオロジクス・オステオバイオロジクス:世界の産業・市場分析

Ortho and Osteobiologics: World Industry and Market Analysis 2014-2024

発行 Visiongain Ltd 商品コード 294348
出版日 ページ情報 英文 195 Pages
納期: 即日から翌営業日
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オーソバイオロジクス・オステオバイオロジクス:世界の産業・市場分析 Ortho and Osteobiologics: World Industry and Market Analysis 2014-2024
出版日: 2014年01月27日 ページ情報: 英文 195 Pages
概要

世界のオーソバイオロジクス市場は2018年に45億6,100万米ドルに達すると予測されています。

当レポートでは、世界のオーソバイオロジクス・オステオバイオロジクス市場を取り上げ、市場動向、市場成長促進・阻害要因をまとめ、地域別・主要国別の市場予測を提示するとともに、主要企業のプロファイルをまとめるなど、概略下記の構成でお届けいたします。

第1章 エグゼクティブサマリー

第2章 オーソバイオロジクスのイントロダクション

  • オーソバイオロジクスとは?
  • オーソバイオロジクスの分類法は?
  • オーソバイオロジクスは骨折治癒機転において重要
  • 自家移植片:「代表的な」骨移植片
  • 同種移植片:最も基本的なオーソバイオロジクス
  • 機械加工骨:オーダーメイドインプラントの作成
  • 脱灰骨基質(DBM):オリジナル骨誘導オーソバイオロジクス
  • 組織形成を促す成長因子、信号
  • 幹細胞:オーソバイオロジクスの将来
  • オーソバイオロジクスの規制
  • 骨粗しょう症:潜行性の命取りとなる病気
  • ビスフォスフォネート(骨吸収抑制剤)から抗体まで:骨密度を改善するための治療
  • 骨粗しょう症の生物学的治療法:市販されたばかりのモノクロナール抗体

第3章 オーソバイオロジクス:世界市場

  • 整形外科装置:290億米ドル以上の市場価値
  • オーソバイオロジクス
  • 最も急速に成長するセグメントは?オーソバイオロジクス市場予測の内訳
  • オーソバイオロジクス市場を導く幹細胞治療
  • 失墜する成長因子は?

第4章 地域・国別市場

  • 米国・日本は重要な国別市場:オーソバイオロジクス市場の地域別分析
  • 日本・ドイツは市場シェアを9%拡大
  • BRIC諸国は市場シェアを38%拡大
  • 各国のオーソバイオロジクス市場分析
  • 米国
  • EU5ヶ国
  • ドイツ
  • 英国
  • フランス
  • イタリア
  • スペイン
  • 日本
  • BRIC諸国
  • 中国
  • ブラジル
  • インド
  • ロシア
  • その他

第5章 骨粗しょう症の生物学的治療法:市場

  • 生物製剤は骨粗しょう症市場の21.9%を獲得
  • 主要な生物製剤ブランド
  • フォルテオが市場に広がる
  • 生物製剤の急成長:世界市場予測
  • 製品売上予測
  • オーソバイオロジクス市場の国別分析
  • 欧州の重要性の低下
  • 米国
  • 欧州の市場シェアは10年以上で27%へ減少
  • ドイツ
  • 英国
  • フランス
  • イタリア
  • スペイン
  • 日本
  • BRIC諸国
  • 中国
  • ブラジル
  • インド
  • ロシア
  • その他

第6章 オーソバイオロジクスのR&Dパイプライン

  • オーソバイオロジクスのバイオマテリアルパイプライン
  • 生物製剤骨粗しょう症パイプライン

第7章 オーソバイオロジクス市場の主要企業

第8章 オーソバイオロジクス市場の定量分析

  • 強みと機会
  • 強み
  • 弱み
  • 機会
  • オーソバイオロジクス市場における機会と脅威
  • 機会
  • 脅威
  • STEP分析
  • 技術要因
  • 政治的要因

第9章 調査インタビュー

第10章 結論

図表

目次

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  • Demineralised bone matrices
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  • Allograft implants.

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  • Prolia
  • Forteo
  • Preotact
  • Romosozumab
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Healthcare in leading national markets - what outlooks for those medical sales?

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  • United States (US)
  • Japan
  • EU leaders - Germany, France, the UK, Italy, and Spain (EU5)
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  • Bisphosphonates to monoclonal antibodies (mAbs) - therapies to improve bone density
  • Bone graft substitutes, orthopaedic devices and biologics suiting minimally-invasive surgery, inc. orthopaedic biomaterials
  • Stem cell therapies and Map3 and i-Factor bone grafts
  • Expanding markets for bone therapy, including effect of demographics on demand
  • Research and development (R&D) pipelines, inc. donor cell therapy, tibia fusing, spinal fusion, mimetic peptides, romosozumab, and blosozumab.

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  • Eli Lilly
  • Amgen
  • Medtronic
  • Johnson & Johnson (DePuy Synthes)
  • NuVasive.

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  • Baxter International
  • Biomet
  • Zimmer
  • RTI Biologics.

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Table of Contents

1. Executive Summary

  • 1.1. Overview of Findings
  • 1.2. Aims and Coverage of this Report
  • 1.3. Structure of this Report
  • 1.4. Research and Analysis Methods
  • 1.5. Terms Related to This Report

2. Introduction to Orthobiologics

  • 2.1. What Are Orthobiologics?
  • 2.2. How Do we Classify Orthobiologics?
  • 2.3. Osteoblasts are Critical in Bone Healing
  • 2.4. Autografts - The "Gold Standard" Bone Graft
  • 2.5. Allografts- The Most Basic of Orthobiologics
  • 2.6. Machined Bones- Creating Customised Implants
  • 2.7. Demineralised Bone Matrix (DBM) - The Original Osteoinductive Orthobiologic
  • 2.8. Growth Factors, the Signals That Encourage Tissue Formation
    • 2.8.1. Bone Morphogenetic Proteins (BMPs) - Supercharging Osteoinduction
  • 2.9. Stem Cells - The Future of Orthobiology
  • 2.10. Regulation of Orthobiologics
    • 2.10.1. The US Approval and Regulation System
    • 2.10.2. The EU Approval and Regulation System
  • 2.11. Osteoporosis - The Insidious Killer
  • 2.12. From Bisphosphonates to Antibodies - Therapies to Improve Bone Density
  • 2.13. Biological Treatments for Osteoporosis - Monoclonal Antibodies Just Hitting the Market

3. Orthobiologics: Global Market, 2014-2024

  • 3.1. Orthopaedic Devices: Worth More Than $29bn in 2012
  • 3.2. Orthobiologics in 2012, a Diverse Multi-Billion Dollar Market
    • 3.2.1. Trends in Orthobiologics, 2012
  • 3.3. Which Segments Will Grow Fastest? Orthobiologics Market Forecast Breakdown, 2014-2024
    • 3.3.1. Steady Growth in Machined Bones, 2014-2024
    • 3.3.2. Growth Spurt in Demineralised Bone Matrices, 2014-2024
    • 3.3.3. Declining Growth Factor Sales, 2014-2024
    • 3.3.4. Accelerated Growth for Bone Substitutes, 2013-2024
    • 3.3.5. Sustained High Growth for Stem-Cells Therapies, 2014-2024
    • 3.3.6. Allograft Market Remains Small, 2014-2024
  • 3.4. Stem-Cell Therapies will lead the Orthobiologics Market
    • 3.4.1. Stem-Cell Therapies: Drivers and Restraints
    • 3.4.2. The Only Osteogenic Bone Graft Substitute
    • 3.4.3. Better than Autograft
    • 3.4.4. Treating at Risk Patients
    • 3.4.5. What is the Alternative?
    • 3.4.6. High Costs Limit Access
    • 3.4.7. Where is the Clinical Evidence?
    • 3.4.8. Human Tissue or Biological Product?
  • 3.5. Growth Factors Fall From Grace
    • 3.5.1. Growth Factor Products: Drivers and Restraints
    • 3.5.2. Autograft Equivalence
    • 3.5.3. Surgeons Still like INFUSE
    • 3.5.4. Off-label Adverse Events
    • 3.5.5. High Unit Cost
    • 3.5.6. Stem-Cell Competition

4. Regional and National Markets, 2014-2024

  • 4.1. US and Japan are Crucial National Markets - Regional Breakdown of the Orthobiologics Market, 2012
  • 4.2. Japan and Germany Increase Market Share by 9%: National Markets, 2012-2018
  • 4.3. BRIC Countries Increase Market Share by 38%: National Markets, 2018-2024
  • 4.4. National Orthobiologic Market Analysis, 2014-2024
  • 4.5. The US Remains Fundamental to Growth: Market Forecast, 2014-2024
    • 4.5.1. Demographics, Drivers and Restraints
  • 4.6. Steady Growth for Orthobiologics in the Five Leading European Nations, 2014-2024
    • 4.6.1. Demographics, Drivers, and Restraints
  • 4.7. Germany Leads Europe: Market Forecast, 2014-2024
    • 4.7.1. Demographics, Drivers, and Restraints
  • 4.8. Expanding Orthobiologics in the UK: Market Forecast, 2014-2024
    • 4.8.1. Demographics, Drivers, and Restraints
  • 4.9. Slow Growth in the French Orthobiologics: Market Forecast, 2014-2024
    • 4.9.1. Demographics, Drivers, and Restraints
  • 4.10. Stuttering Growth for Orthobiologics in Italy: Market Forecast, 2014-2024
  • 4.11. Dwindling Demand in Spain: Market Forecast, 2014-2024
  • 4.12. The Rise of Orthobiologics in Japan: Market Forecast, 2014-2024
    • 4.12.1. Demographics, Drivers, and Restraints
  • 4.13. BRIC Nations to Increase Market Share by 42%: Regional Market Forecast, 2014-2024
  • 4.14. China, the Principal Emerging Nation: Market Forecast, 2014-2024
    • 4.14.1. Demographics, Drivers, and Restraints
  • 4.15 Explosive Growth in Brazilian Orthobiologics: Market Forecast, 2014-2024
    • 4.15.1 Demographics, Drivers, and Restraints
  • 4.16. Too Soon for Orthobiologics in India: Market Forecast, 2014-2024?
  • 4.17. Tepid Growth in Russian Orthobiologics: Market Forecast, 2014-2024
    • 4.17.1. Demographics, Drivers, and Restraints
  • 4.18. Orthobiologics in Minor Nations: Market Forecast, 2014-2024

5. Biological Treatments for Osteoporosis: Market to 2024

  • 5.1. Biologics Take 21.9% of the Osteoporosis Market in 2012
  • 5.2. Leading Biologic Brands
    • 5.2.1. Prolia (Denosumab; Amgen)
    • 5.2.2. Forteo (Teriparatide; Eli Lilly)
    • 5.2.3. Preotact (Recombinant Parathyroid Hormone; NPS Pharmaceuticals)
  • 5.3. Forteo Spearheads the Market in 2012
  • 5.4. Rapid Growth for Biologics: Global Market Forecast, 2014-2024
  • 5.5. Forecasted Product Sales, 2014-2024
    • 5.5.1. Prolia to Drive the Market
    • 5.5.2. Forteo Loses Market Share
  • 5.6. National Breakdown of the Osteobiologics Market, 2012
  • 5.7. Declining Importance of Europe: Forecasted National Markets 2014-2024
  • 5.8. US Dictates Growth: Market Forecast, 2014-2024
    • 5.8.1. Demographics, Drivers, and Restraints
  • 5.9. European Market Share to Decline by 27% Over Ten Years
  • 5.10. German Market to Plateau: Market Forecast 2014-2024
    • 5.10.1. Demographics, Drivers, and Restraints
  • 5.11. Revenue Ceiling in the UK: Market Forecast 2014-2024
    • 5.11.1. Demographics, Drivers, and Restraints
  • 5.12. French Market to Double in Five Years: Market Forecast 2014-2024
    • 5.12.1. Demographics, Drivers, and Restraints
  • 5.13. Price Controls Restrict Italian Growth: Market Forecast 2014-2024
    • 5.13.1. Demographics, Drivers, and Restraints
  • 5.14. Limited Expansion in Spain: Market Forecast 2014-2024
    • 5.14.1. Demographics, Drivers, and Restraints
  • 5.15. Continual Growth in Japan: Market Forecast 2014-2024
    • 5.15.1. Demographics, Drivers, and Restraints
  • 5.16. BRIC Nations to Treble in Value in Less Than Ten Years
  • 5.17 China Increases Market Share by 48%: Market Forecast 2014-2024
    • 5.17.1 Demographics, Drivers, and Restraints
  • 5.18. Brazil Set to Expand by 185%: Market Forecast, 2014-2024
    • 5.18.1. Demographics, Drivers, and Restraints
  • 5.19. Strong Growth but Poor Value in India: Market Forecast 2014-2024
    • 5.19.1. Demographics, Drivers, and Restraints
  • 5.20. Limited Value in Russia: Market Forecast 2014-2024
    • 5.20.1. Demographics, Drivers, and Restraints
  • 5.21. Minor National Markets Forecast, 2014-2024

6. R&D Pipeline for Orthobiologics

  • 6.1. Orthobiologic Biomaterials Pipeline
    • 6.1.1. i-FACTOR (Cerapedics) - Osteoinduction Without Hazardous Growth Factors
    • 6.1.2. Bone Therapeutics, Focussed on Cell Therapies
  • 6.1.2.1. PREOB - Leading Candidate For Non-Union and Osteoporosis
  • 6.1.2.2. ALLOB - Early Stage Donor Cell Therapy
    • 6.1.3. Map3 (RTI Biologics) - Competition for Osteocel and Trinity Evolution
    • 6.1.4. NeoFuse (Mesoblast) - Comparable to the "Gold Standard"
    • 6.1.5. Kuros Biosurgery - Partnered With Synthes to Develop Orthobiologics
      • 6.1.5.1. KUR-111 - An Alternative to Autograft for Fusing the Tibia
      • 6.1.5.2. KUR-113 - Another Parathyroid Hormone for Tibia Fractures
      • 6.1.5.3. KUR-115 - About to Enter Phase II Trials for Spinal Fusion
    • 6.1.6. Amplex (BioSET) - A Mimetic Peptide for BMP-2
    • 6.1.7. UCB-1 (Nell-1; Bone Biologics) - Early Stage Protein with Sclerostin like Potential
  • 6.2. Biological Osteoporosis Pipeline
    • 6.2.1. Romosozumab (AMG 785) - Blockbuster in Waiting
    • 6.2.2. Blosozumab (LY2541546) - Second in Class Sclerostin Antibody
    • 6.2.3. ZP-PTH - Parathyroid by Way Micro Needle Patch
    • 6.2.4. ZT-034 - Will Need More Than Biomarkers for Approval
    • 6.2.5. BA058 - Looking to Compete With Forteo

7. Leading Companies in the Orthobiologics Market, 2013-2014

  • 7.1. Domination of Medtronic and Johnson & Johnson
  • 7.2. Leading Companies in the Orthobiologics Market, 2013
  • 7.3. Medtronic
    • 7.3.1. INFUSE Sales Results
  • 7.4. Johnson & Johnson (DePuy Synthes), Dominant in the Orthobiologics and Medical Device Market
  • 7.5. Vitoss Crucial to Stryker Sales
  • 7.6. Integra LifeSciences, Looking to Innovation with Accell DBMs
  • 7.7. NuVasive - The Leading Force in the Stem Cell Market
  • 7.8. RTI Biologics, Producing the Full Spectrum of Orthobiologics
  • 7.9. Baxter International, Acquiring Its Way into the Market
  • 7.10. Biomet - Big in Orthopaedics, Building Up in Orthobiologics
  • 7.11. Wright Medical, Shifting Focus into the Ankle Market
  • 7.12. Globus Medical- The Fastest Growing Orthopaedics Company
  • 7.13. Zimmer Spine, Weak Sales for a Multinational Powerhouse
  • 7.14. Bacterin - Exclusively Biological Business Model
  • 7.15. Olympus Biotech, Focussed on Minimally Invasive Surgery
  • 7.16. Fragmented Market for Smaller Companies
  • 7.17. Shift to High Margin Products and Specialisation

8. Qualitative Analysis of the Orthobiologics Market, 2014

  • 8.1. Strengths and Weaknesses of the Orthobiologics Market
  • 8.2. Strengths
    • 8.2.1. Eli Lilly and Amgen Dominate the Biological Osteoporosis Market
    • 8.2.2. Biologics Suit Minimally Invasive Surgery
    • 8.2.3. Patients Stick to Biologics
  • 8.3. Weaknesses
    • 8.3.1. Intense Competition in the Biomaterials Market
    • 8.3.2. Are Biologics Worth the Bill?
    • 8.3.3. Soaring Clinical Development Costs
    • 8.3.4. The Silent Disease
  • 8.4. Opportunities and Threats in the Orthobiologics Market
  • 8.5. Opportunities
    • 8.5.1. Increase Diagnosis Rates to Increase Sales
    • 8.5.2. Beat the Best in Class
    • 8.5.3. Access to the Surgical Community
    • 8.5.4. Replacing Autografts
  • 8.6. Threats
    • 8.6.1. Generic Bisphosphonate Competition
    • 8.6.2. Getting Paid in the US and Europe
    • 8.6.3. Accessing the Asian Markets
    • 8.6.4. Treatment Only as a Last Resort
  • 8.7. Social, Technological, Economic, and Political (STEP) Analysis
    • 8.7.1. Social Factors
    • 8.7.2. Ageing Populations in the Developed and BRIC Nations
    • 8.7.3. Unhealthy Lifestyles and the Global rise in Prevalence of Diabetes
  • 8.8. Technological Factors
    • 8.8.1. Harnessing Stem Cell and Gene Based Therapies
  • 8.9. Economic Factors
    • 8.9.1. Reimbursement and Cost Cutting in the Europe and the US
    • 8.9.2. Free Trade within the European Union, Parallel Trade and Arbitrage
    • 8.9.3. Record Low Cost of Borrowing - What Happens When the Music's Over?
  • 8.10. Political Factors
    • 8.10.1. The Patient Protection and Affordable Care Act in the US

9. Research Interviews

  • 9.1. Interview with an Executive at an International Orthobiologics Company
    • 9.1.1. Matching Products to Patients at Risk
    • 9.1.2. Demanding Clinical and Economic Evidence
    • 9.1.3. Stem Cells are Critical
    • 9.1.4. Developed Markets and Latin America Drive Growth
    • 9.1.5. Too Early for China?
    • 9.1.6. Moving Away From Basic Bone Substitutes
    • 9.1.7. Medical Education is Crucial
    • 9.1.8. Safety and Efficacy of BMP Products
  • 9.2. Interview with Dr Nancy Epstein M.D., Chief of Neurosurgical and Spine Education, Winthrop University Hospital
    • 9.2.1. INFUSE to be taken off the Market
    • 9.2.2. An "Off-label" Product NOT Approved by the Food and Drug Administration
    • 9.2.3. Surgeons Still Demand Innovation for Patients at Risk
    • 9.2.4. Gene Therapy

10. Conclusions

  • 10.1. Continued Growth in Orthobiologics
    • 10.1.1. Stem-Cell Products Dominate the Market
    • 10.1.2. Decline in Growth Factor Sales
    • 10.1.3. US Continues to Dominate the Market
  • 10.2. Biologics Break Osteoporosis
    • 10.2.1. Patient Population Explosion
    • 10.2.2. Prolia and Romosozumab Lead the Market
    • 10.2.3. Early Access to Japan

List of Tables

  • Table 2.1: Mechanisms Involved in Bone Grafting
  • Table 3.1: Global Orthopaedic Device Market: Segment Revenue ($bn) and Market Share (%), 2012
  • Table 3.2: Global Orthobiologics Market: Segment Revenue ($m) and Market Share (%), 2012
  • Table 3.3: Global Orthobiologics Market Forecasts: Segment Revenue ($m), Annual Growth Rate (%), Segment Market Share (%), CAGR (%), 2012-2018
  • Table 3.4: Global Orthobiologics Market Forecasts: Segment Revenue ($m), Annual Growth Rate (%), Segment Market Share (%), CAGR (%), 2018-2024
  • Table 3.5: Global Machined Bone Market Forecast: Revenue ($m), Annual Growth Rate (%), CAGR (%), 2013-2024
  • Table 3.6: Global Demineralised Bone Matrix Market Forecast: Revenue ($m), Annual Growth Rate (%), CAGR (%), 2013-2024
  • Table 3.7: Global Growth Factor Market Forecast: Revenue ($m), Annual Growth Rate (%), CAGR (%), 2013-2024
  • Table 3.8: Global Bone Substitute Market Forecast: Revenue ($m), Annual Growth Rate (%), CAGR (%), 2013-2024
  • Table 3.9: Global Stem Cell Therapy Market Forecast: Revenue ($m), Annual Growth Rate (%), CAGR (%), 2013-2024
  • Table 3.10: Global Allograft Bone Market Forecast: Revenue ($m) Annual Growth Rate (%), CAGR (%), 2013-2024
  • Table 3.11: INFUSE Revenue Forecast: Revenue ($m), Annual Growth Rate (%), Peak of Sales (%), CAGR (%), 2011-2024
  • Table 4.1: Global Orthobiologics Market: National Market Revenue ($m), Market Share (%), 2012
  • Table 4.2: Global Orthobiologic Market: National Market Revenue ($m), Market Share (%), 2018
  • Table 4.3: Global Orthobiologic Market: National Market Revenue ($m), Market Share (%), 2024
  • Table 4.4: Global Orthobiologics Market: Regional Revenue Forecasts ($m), Annual Growth (%), Global Market Share (%), CAGR (%), 2013-2018
  • Table 4.5: Global Orthobiologics Market: Regional Revenue Forecasts($m), Annual Growth (%), Global Market Share (%), CAGR (%), 2018-2024
  • Table 4.6: US Orthobiologic Market: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 4.7: Five Leading European Orthobiologic Markets: National Revenue Forecasts ($m), Annual Growth Rate (%), European Market Share (%), CAGR (%), 2013-2018
  • Table 4.8: Five Leading European Orthobiologic Markets: National Revenue Forecasts ($m), Annual Growth Rate (%), European Market Share (%), CAGR (%), 2018-2024
  • Table 4.9: German Orthobiologic Market: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 4.10: UK Orthobiologic Market: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 4.11: French Orthobiologic Market: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 4.12: Italian Orthobiologic Market: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 4.13: Spanish Orthobiologic Market: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 4.14: Japanese Orthobiologic Market: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 4.15: BRIC Orthobiologic Markets: Revenue Forecasts ($m), Annual Growth (%), BRIC Market Share (%), CAGR (%), 2013-2018
  • Table 4.16: BRIC Orthobiologic Markets: Revenue Forecasts ($m), Annual Growth (%), BRIC Market Share (%), CAGR (%), 2018-2024
  • Table 4.17: Chinese Orthobiologic Market: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 4.18: Brazilian Orthobiologic Market: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 4.19: Indian Orthobiologic Market: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 4.20: Russian Orthobiologic Market: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 4.21: Minor National Orthobiologic Markets: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 5.1: Global Osteoporosis Market: Segment Revenue ($m), Market Share (%), 2012
  • Table 5.2: Biologics Osteoporosis Treatments, Product Revenue ($m) and Market Share (%), 2012 and 2013
  • Table 5.3: Global Osteoporosis Biologics Market Forecast: Total Revenue ($m), Annual Growth Rate (%), CAGR (%), 2013-2024
  • Table 5.4: Global Osteoporosis Biologics Market Forecasts: Product Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2018
  • Table 5.5: Global Osteoporosis Biologics Market Forecasts: Product Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2018-2024
  • Table 5.6: National Markets for Osteoporosis Biologics: Revenue ($m), Market Share (%), 2012
  • Table 5.7: Global Osteoporosis Biologics Market: Regional Revenue Forecasts ($m), Annual Growth (%), Global Market Share (%), CAGR (%), 2013-2018
  • Table 5.8: Global Osteoporosis Biologics Market: Regional Revenue Forecasts ($m), Annual Growth (%), Global Market Share (%), CAGR (%), 2018-2024
  • Table 5.9: US Market for Osteoporosis Biologics: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 5.10: Reported Costs of Biological Osteoporosis Treatments in the US and UK Markets, 2013
  • Table 5.11: Five Leading European Nationals Markets for Osteoporosis Biologics: Revenue Forecasts ($m), Annual Growth Rate (%), European Market Share (%), Global Market Share (%), CAGR (%), 2013-2018
  • Table 5.12: Five Leading European Nationals Markets for Osteoporosis Biologics: Revenue Forecasts ($m), Annual Growth Rate (%), European Market Share (%), Global Market Share (%), CAGR (%), 2018-2024
  • Table 5.13: German Market for Osteoporosis Biologics: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 5.14: UK Market for Osteoporosis Biologics: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 5.15: French Market for Osteoporosis Biologics: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 5.16: Italian Market for Osteoporosis Biologics: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 5.17: Spanish Market for Osteoporosis Biologics: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 5.18: Japanese Market for Osteoporosis Biologics: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 5.19: BRIC Markets for Osteoporosis Biologics: National Revenue Forecasts ($m), Annual Growth Rate (%), BRIC Market Share (%), Global Market Share (%), CAGR (%), 2013-2018
  • Table 5.20: BRIC Markets for Osteoporosis Biologics: National Revenue Forecasts ($m), Annual Growth Rate (%), BRIC Market Share (%), Global Market Share (%), CAGR (%), 2018-2024
  • Table 5.21: Chinese Market for Osteoporosis Biologics: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 5.22: Brazilian Market for Osteoporosis Biologics: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 5.23: Indian Market for Osteoporosis Biologics: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 5.24: Russian Market for Osteoporosis Biologics: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 5.25: Minor National Markets for Osteoporosis Biologics: Revenue ($m), Annual Growth Rate (%), Global Market Share (%), CAGR (%), 2013-2024
  • Table 6.1: Orthobiologic Biomaterials in Development, 2013
  • Table 6.2: Osteoporosis Biologics in Development, 2013
  • Table 7.1: Leading Orthobiologics Companies: Revenue ($m), Market Share (%), 2012
  • Table 7.2: INFUSE (rhBMP-2) Sales: Revenue ($m), Annual Growth Rate (%), Peak of Sales (%), CAGR, 2010-2014
  • Table 7.3: Smaller Orthobiologics Manufacturers: Listed A-E, 2013
  • Table 7.4: Smaller Orthobiologics Manufacturers: Listed G-T, 2013

List of Figures

  • Figure 3.1: Orthopaedic Devices Market: Segment Market Shares (%), 2012
  • Figure 3.2: Global Orthopaedics Biomaterials Market: Segment Market Shares (%), 2012
  • Figure 3.3: Segmented Orthobiologics Market Forecast: Segment Revenues ($m), 2013-2024
  • Figure 3.4: Total Global Orthobiologics Forecast: Revenue ($m), 2013-2024
  • Figure 3.5: Machined Bone Market Forecast: Revenue ($m), 2013-2024
  • Figure 3.6: Global Demineralised Bone Matrix Market Forecast: Revenue ($m), 2013-2024
  • Figure 3.7: Global Growth Factor Market Forecast: Revenue ($m),2013-2024
  • Figure 3.8: Global Bone Substitute Market Forecast: Revenue ($m), 2013-2024
  • Figure 3.9: Global Stem Cell Therapy Market Forecast: Revenue ($m), 2013-2024
  • Figure 3.10: Global Allograft Bone Market Forecast: Revenue ($m), 2013-2024
  • Figure 3.11: Stem-Cell Therapy Market: Drivers and Restraints, 2014-2024
  • Figure 3.12: INFUSE Revenue Forecast: Revenue ($m), 2013-2024
  • Figure 3.13: Growth Factor Market: Drivers and Restraints, 2014-2024
  • Figure 4.1: Global Orthobiologics Market: National Market Shares (%), 2012
  • Figure 4.2: Global Orthobiologic Market: National Market Shares (%), 2018
  • Figure 4.3: Global Orthobiologic Market: National Market Shares (%), 2024
  • Figure 4.4: Global Orthobiologics Market: Regional Revenues ($m), 2013-2024
  • Figure 4.5: US Orthobiologic Market: Revenue ($m), 2013-2024
  • Figure 4.6: Five Leading European Orthobiologic Markets: National Market Revenues ($m), 2013-2024
  • Figure 4.7: German Orthobiologic Market: Revenue ($m), 2013-2024
  • Figure 4.8: UK Orthobiologic Market: Revenue ($m), 2013-2024
  • Figure 4.9: French Orthobiologic Market: Revenue ($m), 2013-2024
  • Figure 4.10: Italian Orthobiologic Market: Revenue ($m), 2013-2024
  • Figure 4.11: Spanish Orthobiologic Market: Revenue ($m), 2013-2024
  • Figure 4.12: Japanese Orthobiologic Market: Revenue ($m), 2013-2024
  • Figure 4.13: BRIC Orthobiologic Markets: National Revenues ($m), 2013-2024
  • Figure 4.14: Chinese Orthobiologic Market: Revenue ($m), 2013-2024
  • Figure 4.15: Brazilian Orthobiologic Market: Revenue ($m), 2013-2024
  • Figure 4.16: Indian Orthobiologic Market: Revenue ($m), 2013-2024
  • Figure 4.17: Russian Orthobiologic Market: Revenue ($m), 2013-2024
  • Figure 4.18: Minor National Orthobiologic Market: Revenue ($m), 2013-2024
  • Figure 5.1: Global Osteoporosis Market, Segment Market Shares (%), 2012
  • Figure 5.2: Biologics Osteoporosis Treatments: Product Revenue ($m), 2012 and 2013
  • Figure 5.3: Global Osteoporosis Biologics Market Forecast: Total Revenue ($m), 2013-2024
  • Figure 5.4: Global Osteoporosis Biologics Market Forecast: Product Revenues ($m), 2013-2024
  • Figure 5.5: Global Prolia Market Forecast: Revenue ($m), 2013-2024
  • Figure 5.6: Global Forteo Market Forecast: Revenue ($m), 2013-2024
  • Figure 5.7: Global Preotact Market Forecast: Revenue ($m), 2013-2024
  • Figure 5.8: Global Romosozumab Market Forecast: Revenue ($m), 2013-2024
  • Figure 5.9: Global Generics Market: Revenue ($m), 2013-2024
  • Figure 5.10: National Markets for Osteoporosis Biologics: Market Shares (%), 2012
  • Figure 5.11: Global Osteoporosis Biologics Market: Regional Revenues ($m), 2013-2024
  • Figure 5.12: US Market for Osteoporosis Biologics: Revenue ($m), 2013-2024
  • Figure 5.13: Five Leading European National Markets for Osteoporosis Biologics: Revenues ($m), 2013-2024
  • Figure 5.14: German Market for Osteoporosis Biologics: Revenue ($m), 2013-2024
  • Figure 5.15: UK Market for Osteoporosis Biologics: Revenue ($m), 2013-2024
  • Figure 5.16: French Market for Osteoporosis Biologics: Revenue ($m), 2013-2024
  • Figure 5.17: Italian Market for Osteoporosis Biologics: Revenue ($m), 2013-2024
  • Figure 5.18: Spanish Market for Osteoporosis Biologics: Revenue ($m), 2013-2024
  • Figure 5.19: Japanese Market for Osteoporosis Biologics: Revenue ($m), 2013-2024
  • Figure 5.20: BRIC Markets for Osteoporosis Biologics: Revenues ($m), 2013-2024
  • Figure 5.21: Chinese Market for Osteoporosis Biologics: Revenue ($m), 2013-2024
  • Figure 5.22: Brazilian Market for Osteoporosis Biologics: Revenue ($m), 2013-2024
  • Figure 5.23: Indian Market for Osteoporosis Biologics: Revenue ($m), 2013-2024
  • Figure 5.24: Russian Market for Osteoporosis Biologics: Revenue ($m), 2013-2024
  • Figure 5.25: Minor National Markets for Osteoporosis Biologics: Revenue ($m), 2013-2024
  • Figure 7.1: Leading Orthobiologics Companies: Revenues ($m), 2012
  • Figure 7.2: INFUSE (rhBMP-2) Sales: Revenue ($m), 2010-2014
  • Figure 8.1: Orthobiologics Market: Strengths and Weaknesses, 2014-2024
  • Figure 8.2: Orthobiologics Market: Opportunities and Threats, 2014-2024

Companies Listed

  • AAP Implante
  • Allosource
  • Alphatec
  • Amgen
  • Angel Biotechnology
  • ApaTech
  • Arthrocare
  • Atheriocyte Medical Systems Inc
  • Athersys
  • Azelon Pharmaceuticals
  • Bacterin
  • Baxter
  • Berkeley Advanced Biomaterials Inc
  • Biocomposites
  • Biocoral
  • Biological Therapies
  • Biomatlante
  • Biomet
  • BioMimetic Therapeutics
  • BioSET
  • BioTissue
  • BonAlive Biomaterials
  • Bone Biologics
  • Bone Solutions
  • Bone Therapeutics
  • BoneSupport
  • Brazilian Unified Health System (SUS)
  • Cardium Therapeutics
  • Celltech
  • Centre for Devices and Radiological Health (CDRH)
  • Ceramisys
  • Cerapedics
  • co.don
  • Collagen Matrix
  • Curasan
  • Cytomedix
  • Daiichi Sankyo
  • DePuy Synthes
  • Eli Lilly
  • ETEX Corporation
  • European Medicines Agency (EMA)
  • European Union (EU)
  • Exactech
  • Fitch Ratings
  • Food and Drug Administration (FDA)
  • Forest Laboratories
  • Geistlich Biomaterials
  • German Institute for Quality and Efficiency in Healthcare (IQWiG)
  • GlaxoSmithKline (GSK)
  • Globus Medical
  • Graftys
  • Histogenics Corporation
  • Integra LifeSciences
  • ISTO Technologies
  • Johnson & Johnson
  • Kasios
  • Kensey Nash
  • Kinetic Concepts
  • Kuros Biosurgery
  • Lindare Medical
  • Medtronic
  • Merck & Co
  • Mesoblast
  • MicroPort Medical
  • MiMedx Group
  • Monet Medical
  • Musculoskeletal Transplant Foundation
  • National Health Service (NHS)
  • National Institute for Clinical Excellence (NICE)
  • NovaBone Products LLC
  • Novartis
  • NPS Pharmaceuticals
  • NuVasive
  • Nycomed
  • Olympus Biotech
  • Orteq Bioengineering
  • Orthofix
  • Orthovita
  • Osiris Therapeutics
  • OsteoGeneX
  • Osteotech
  • Parcell Laboratories
  • Pharma and Medical Devices Agency (PMDA)
  • Pioneer Surgical Technologies
  • PolyNovo Biomaterials
  • Progenteq
  • Radius Health
  • Roche
  • Royal DSM
  • RTI Biologics
  • Scorpion Medical
  • Spinal Restoration
  • SpineSmith Partners LP
  • State Food and Drug Administration (SFDA, China)
  • Stryker
  • Takeda
  • Teknimed
  • Teva Pharmaceutical Industries
  • Tigenix
  • Tissue Banks International
  • Tissue Genesis
  • TissueGene
  • Tornier
  • UCB
  • Winthrop University Hospital
  • World Health Organization (WHO)
  • Wright Medical
  • Yale University
  • Zimmer
  • Zosano Pharma
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