株式会社グローバルインフォメーション
TEL: 044-952-0102
市場調査レポート

癌治療のための個別化遺伝子療法市場

The Market for Personalized Gene Therapy Treatments for Cancer

発行 Kalorama Information 商品コード 323161
出版日 ページ情報 英文 150 Pages
即納可能
価格
本日の銀行送金レート: 1USD=115.27円で換算しております。
Back to Top
癌治療のための個別化遺伝子療法市場 The Market for Personalized Gene Therapy Treatments for Cancer
出版日: 2014年12月23日 ページ情報: 英文 150 Pages
概要

近年、外科手術や化学療法の変わりに、遺伝子療法を用いて、癌の治療の個別化医療を展開しよう試みが進められています。遺伝子療法の場合、異常のある遺伝子を正常な遺伝子と取り替えるか、遺伝子の反応(何かに反応する/しない)を変更させるかします。遺伝子療法のアプローチはすべて同一というわけではなく、各々の癌に合わせた最適な治療法が別々に存在します。

当レポートでは、癌治療のための遺伝子療法の潜在的市場について包括的に分析し、遺伝子療法の概要・種類や、各国・各企業の開発に向けた取り組み、遺伝子療法による癌治療の可能性および問題点、潜在的な市場規模、各種癌市場の詳細動向(治療薬市場の全体的規模と見通し、遺伝子療法の可能性、研究開発活動の進捗状況、主要企業のプロファイルなど)といった情報を盛り込んでお届けいたします。

エグゼクティブ・サマリー

遺伝子療法の概要

  • 遺伝学
  • コスト削減
  • 遺伝子療法とは何か?
  • 遺伝子療法の種類
    • 体細胞遺伝子療法
    • 生殖系細胞の遺伝子療法
  • 遺伝子療法の活用分野
  • 規制の概要
    • 希用薬指定のインセンティブ
  • ファストトラック・ブレークスルー療法・迅速承認・優先承認の概要
  • 米国各州の「Right to Try(新薬使用許可)」法案

癌と遺伝子療法

  • 癌治療市場の進化の経緯
  • 薬理ゲノミクス
  • 癌治療のための遺伝子療法の使用
  • ウイルスベクターとDNA療法
  • 癌の治癒:究極のゴール
  • 世界的な癌の影響度
  • 遺伝子療法と癌発生の概要
  • 発生のリスク
  • 新規癌治療薬「Allovectin-7」の開発に対する昨今の問題
  • 開発プログラム
  • 保険と医療費償還の問題

膀胱癌むけ遺伝子療法の市場見通し

  • 膀胱癌の概要
  • 発症率・死亡率の傾向
  • 現在の治療アプローチ
  • 遺伝子療法の研究活動
  • 市場機会
    • 膀胱癌治療市場の現状
    • 遺伝子療法の潜在的市場規模:膀胱癌の場合

脳癌の遺伝子療法の市場見通し

乳癌の遺伝子療法の市場見通し

大腸癌の遺伝子療法の市場見通し

頭部・頚部癌の遺伝子療法の市場見通し

白血病の遺伝子療法の市場見通し

肝臓癌の遺伝子療法の市場見通し

肺癌の遺伝子療法の市場見通し

リンパ腫の遺伝子療法の市場見通し

黒色腫の遺伝子療法の市場見通し

卵巣癌の遺伝子療法の市場見通し

膵臓癌の遺伝子療法の市場見通し

前立腺癌の遺伝子療法の市場見通し

遺伝子療法とその他の癌

  • その他の癌の概要
    • 食道癌
    • 多発性骨髄腫
    • 腎臓癌
    • 甲状腺癌
  • 発症率・死亡率の傾向
  • 遺伝子療法の研究活動

癌市場における遺伝子療法:サマリーと展望

  • 概要
  • 癌治療の焦点:サマリー
  • 癌の遺伝子療法:予測分析
  • 各々の癌市場への遺伝子療法の影響度

市場参入企業および資金提供企業の一覧

分析対象企業(研究活動、背景事情)

  • Adaptimmune Ltd.
  • Advantagene, Inc.
  • Amgen, Inc.
  • Bellicum Pharmaceuticals, Inc.
  • BioCancell Ltd.
  • Blubird Bio
  • Celgene
  • Celsion Corporation
  • Chengdu Shi Endor Biological Engineering Technology Co., Ltd.
  • Cold Genesys, Inc.
  • Genprex, Inc.
  • MaxiVax SA
  • 桃太郎源
  • MultiVir, Inc.
  • OncoSec Medical, Inc.
  • Sevion Therapeutics, Inc.
  • SynerGene Therapeutics, Inc.
  • タカラバイオ
  • Tocagen, Inc.
  • VBL Therapeutics Ltd.
  • Ziopharm Oncology, Inc.
目次
Product Code: KLI5421818

This report, The Market for Personalized Gene Therapy Treatments For Cancer provides an exhaustive review of the market potential for relatively new approach in cancer research. It involves modification of genes instead of using a surgical method or chemical drug product. Essentially, gene therapies replace an abnormal gene with a normal gene, or changes the response of a gene (turn on or off). Not all of the approaches to gene therapy are the same, and different cancers appear to respond better to different therapies.

Several gene therapy technologies have the ability to work in combination with other treatment options to enhance the effectiveness of a therapeutic regimen. Gene therapy is also designed to target specific cells making treatment much less damaging to healthy cells.

This report discusses those treatments and estimates market size and market potential for personalized medicine using gene therapy. As part of its data offering, the report provides disease incidence, gene therapy product developments and market forecasts for the following types of cancer:

  • Bladder Cancer
  • Brain Cancer
  • Breast Cancer
  • Head & Neck
  • Colorectal Cancer
  • Leukemia Cancer
  • Liver Cancer
  • Lung Cancer
  • Lymphoma
  • Melanoma
  • Leukemia
  • Pancreatic Cancer
  • Prostate Cancer
  • Ovarian Cancer
  • Other Cancer

In addition the report provides:

  • Overview of Gene Therapy
  • Overall Market Size and Forecast
  • Cancer Therapeutic Market Totals
  • Discussion of Somati vs. Germ Line Gene Therapy
  • R&D Activities
  • Company Profiles

Historically, cancer treatments have been very invasive and detrimental process to the body. However, there are numerous new techniques available for those with cancer that are not as invasive and detrimental to the body as a whole. These treatments range from the severely alternative to the more traditional. Newer alternative treatments are more precise and much less invasive as some of the traditional methods. Gene therapy is the most prominent new form of these alternative treatments. It is being studied as a way to change how a cell functions, for example, by stimulating the cells of the immune system to attack cancer cells.

Companies discussed in this report include those which have registered trials in Phase I through Phase III development and have promising development activities. These include:

  • Adaptimmune Ltd.
  • Advantagene, Inc.
  • Amgen, Inc.
  • Bellicum Pharmaceuticals, Inc.
  • BioCancell Ltd.
  • Blubird Bio
  • Celgene
  • Celsion Corporation
  • Chengdu Shi Endor Biological Engineering Technology Co., Ltd.
  • Cold Genesys, Inc.
  • Genprex, Inc.
  • MaxiVax SA
  • Momotaro-Gene, Inc.
  • MultiVir, Inc.
  • OncoSec Medical, Inc.
  • Sevion Therapeutics, Inc.
  • SynerGene Therapeutics, Inc.
  • Takara Bio, Inc.
  • Tocagen, Inc.
  • VBL Therapeutics Ltd.
  • Ziopharm Oncology, Inc.

Table of Contents

EXECUTIVE SUMMARY

  • Overview and Scope of Study
  • Methodology
  • How Personalized Medicine is Changing the Cancer Market
  • Market Potential for Gene Therapy in Cancer

GENE THERAPY OVERVIEW

  • Genetics
  • Reducing Costs
  • What is Gene Therapy?
  • Types of Gene Therapy
  • Somatic Gene Therapy
  • Germ Line Gene Therapy
  • Gene Therapy Applications
  • Regulation Overview
  • Orphan Drug Designation Incentives
  • Fast Track, Breakthrough Therapy, Accelerated Approval and Priority Review
  • Fast Track
  • Breakthrough Therapy
  • Accelerated Approval
  • Priority Review
  • State ‘Right to Try' Laws

CANCER AND GENE THERAPY

  • How has the Cancer Treatment Market Evolved?
  • Pharmacogenomics
  • Using Gene Therapy to Treat Cancer
  • Viral Vectors and DNA Therapies
  • Curing Cancer - The Ultimate Goal
  • Global Cancer Impact
  • Gene Therapy and Cancer Development Overview
  • Development Risk
  • A Recent Disappointment in Novel Cancer Therapy Development - Allovectin-7
  • Development Programs
  • Insurance and Reimbursement Issues

GENE THERAPY OUTLOOK IN BLADDER CANCER

  • Bladder Cancer Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • BioCancell Ltd.
  • Research Activities
  • Company Background
  • Cold Genesys, Inc.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Bladder Cancer
  • Potential Market for Gene Therapy in Bladder Cancer

GENE THERAPY OUTLOOK IN BRAIN CANCER

  • Brain Cancer Overview
  • Glioblastoma
  • Neuroblastoma
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • Advantagene, Inc.
  • Research Activities
  • Company Background
  • BioCancell Ltd.
  • Research Activities
  • Company Background
  • Celsion Corporation
  • Research Activities
  • Company Background
  • Tocagen, Inc.
  • Research Activities
  • Company Background
  • VBL Therapeutics Ltd.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Brain Cancer
  • Potential Market for Gene Therapy in Brain Cancer

GENE THERAPY OUTLOOK IN BREAST CANCER

  • Breast Cancer Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • ZIOPHARM Oncology, Inc.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Breast Cancer
  • Potential Market for Gene Therapy in Breast Cancer

GENE THERAPY OUTLOOK IN COLORECTAL CANCER

  • Colorectal Cancer Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • MultiVir, Inc.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Colorectal Cancer
  • Potential Market for Gene Therapy in Colorectal Cancer

GENE THERAPY OUTLOOK IN HEAD & NECK CANCER

  • Head and Neck Cancer Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • Chengdu Shi Endor Biological Engineering Technology Co., Ltd
  • Research Activities
  • Market Opportunity
  • Current Market for Treating Head and Neck Cancer
  • Potential Market for Gene Therapy in Head and Neck Cancer

GENE THERAPY OUTLOOK IN LEUKEMIA

  • Leukemia Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • Bellicum Pharmaceuticals, Inc.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Leukemia
  • Potential Market for Gene Therapy in Leukemia

GENE THERAPY OUTLOOK IN LIVER CANCER

  • Liver Cancer Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • MultiVir, Inc.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Liver Cancer
  • Potential Market for Gene Therapy in Liver Cancer

GENE THERAPY OUTLOOK IN LUNG CANCER

  • Lung Cancer Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • Genprex, Inc.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Lung Cancer
  • Potential Market for Gene Therapy in Lung Cancer

GENE THERAPY OUTLOOK IN LYMPHOMA

  • Lymphoma Overview
  • Non-Hodgkin's Lymphoma
  • Hodgkin's Lymphoma
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • Bellicum Pharmaceuticals, Inc.
  • Research Activities
  • Company Background
  • Sevion Therapeutics, Inc.
  • Research Activities
  • Company Background
  • OncoSec Medical, Inc.
  • Research Activities
  • Company Background
  • Takara Bio, Inc.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Lymphoma
  • Potential Market for Gene Therapy in Lymphoma

GENE THERAPY OUTLOOK IN MELANOMA

  • Melanoma Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • Adaptimmune Limited
  • Research Activities
  • Company Background
  • Amgen, Inc.
  • Research Activities
  • Company Background
  • OncoSec Medical, Inc.
  • Research Activities
  • Company Background
  • ZIOPHARM Oncology, Inc.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Melanoma
  • Potential Market for Gene Therapy in Melanoma

GENE THERAPY OUTLOOK IN OVARIAN CANCER

  • Ovarian Cancer Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • Adaptimmune Limited
  • Research Activities
  • Company Background
  • BioCancell Ltd.
  • Research Activities
  • Company Background
  • Celsion Corporation
  • Research Activities
  • Company Background
  • VBL Therapeutics Ltd.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Ovarian Cancer
  • Potential Market for Gene Therapy in Ovarian Cancer

GENE THERAPY OUTLOOK IN PANCREATIC CANCER

  • Pancreatic Cancer Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • Advantagene, Inc.
  • Research Activities
  • Company Background
  • BioCancell Ltd.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Pancreatic Cancer
  • Potential Market for Gene Therapy in Pancreatic Cancer

GENE THERAPY OUTLOOK IN PROSTATE CANCER

  • Prostate Cancer Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • Advantagene, Inc.
  • Research Activities
  • Company Background
  • Momotaro-Gene, Inc.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Prostate Cancer
  • Potential Market for Gene Therapy in Prostate Cancer

GENE THERAPY AND OTHER CANCERS

  • Other Cancer Overview
  • Esophagus Cancer
  • Multiple Myeloma
  • Renal Cancer
  • Thyroid Cancer
  • Trends in Incidence and Mortality
  • Esophageal Cancer
  • Multiple Myeloma
  • Renal Cancer
  • Thyroid Cancer
  • Gene Therapy Research Activities for Other or Unspecific Cancer
  • Advantagene, Inc.
  • Research Activities
  • Company Background
  • Bluebird Bio
  • Research Activities
  • Company Background
  • MaxiVAX
  • Research Activities
  • Company Background
  • OncoSec Medical, Inc.
  • Research Activities
  • Company Background
  • Sevion Therapeutics, Inc.
  • Research Activities
  • Company Background
  • Takara Bio, Inc.
  • Research Activities
  • Company Background
  • VBL Therapeutics Ltd.
  • Research Activities
  • Company Background
  • Other Companies

GENE THERAPY IN CANCER MARKET SUMMARY AND OUTLOOK

  • Overview
  • Cancer Focus Summary
  • Cancer Gene Therapy Forecast Analysis
  • Impact of Gene Therapy on Specific Cancer Markets

INDUSTRY PARTICIPANTS AND CONTRIBUTORS

Back to Top