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創薬業務のアウトソーシング:開発業務受託機関(CRO)の世界市場

Outsourcing in Drug Discovery: The Contract Research Organization (CRO) Market, 8th Edition

発行 Kalorama Information 商品コード 302663
出版日 ページ情報 英文 342 Pages
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創薬業務のアウトソーシング:開発業務受託機関(CRO)の世界市場 Outsourcing in Drug Discovery: The Contract Research Organization (CRO) Market, 8th Edition
出版日: 2018年03月20日 ページ情報: 英文 342 Pages
概要

製薬産業におけるブロックバスター薬の欠如や、より効果的なバイオ医薬品を求める患者・製薬企業の要望、新薬開発を目指した企業間の競争激化といった事情を反映して、創薬業務のアウトソーシング (外部委託) やオフショアリング (海外委託) が世界各国で進展しつつあります。

当レポートでは、世界の創薬業務アウトソーシングの市場について分析し、市場の基本構造や最新情勢、市場規模の推移と見通し、特に成長が著しい分野、アウトソーシングの利点と課題、主要市場 (中国・インド・東欧) の主な傾向、CRO (開発業務受託機関) の選択基準、外注化の際の意思決定要因、主なCROでのベストプラクティス、戦略的・戦術的アウトソーシングモデルのあり方などについて調査すると共に、主要企業の概略に関する情報を取りまとめてお届けいたします。

エグゼクティブ・サマリー

創薬アウトソーシング:概略

  • 背景事情
    • 新薬承認申請 (NME)・生物製剤承認申請 (BLA) の認証件数
    • 研究開発 (R&D) 支出額
    • パイプライン製品の増加
  • 創薬業務のアウトソーシング
  • アウトソーシング時の意思決定
    • アウトソーシング計画の立案
    • 意思決定の基準
  • オフショア・アウトソーシングの際に考慮すべき事項
    • オフショア・アウトソーシングの利点
    • オフショア・アウトソーシングの懸念事項
  • CRO (開発業務受託機関) の選定
    • イントロダクション
    • 適切なCROの選定
  • 国際アウトソーシング

創薬過程

  • イントロダクション
    • 創薬の作業段階
  • 創薬過程の迅速化
    • 創薬過程で用いられる技術
    • 創薬過程のボトルネック
  • 効率改善のためのアウトソーシング
  • 新規技術にアクセスするためのアウトソーシング
    • バイオインフォマティクス
    • ラブオンチップ:創薬過程におけるマイクロ流体工学

創薬過程のアウトソーシング

  • 概要
    • 従来型の創薬モデルからの変化
  • 創薬アウトソーシング:使い勝手の良いコア管理ツール
  • CRO (開発業務受託機関)
    • イントロダクション
    • CROの役割
    • アウトソーシングのモデル
    • 事業提携の成功には、効果的なコミュニケーションが不可欠である
    • 知的所有権 (IP) 保護に関する問題の緩和
  • 創薬業務のアウトソーシング (海外委託)
    • イントロダクション
    • アジアでの創薬アウトソーシングの急成長
    • アジアでの創薬受託業務の進化
  • 中国へのアウトソーシング
    • イントロダクション
    • 多国籍企業が中国国内に研究開発施設を設立
    • 中国のCRO
    • WuXi AppTec:中国最大のCRO
    • 中国初のCROアライアンス
    • FDA (米国食品医薬品局) の中国オフィス
    • 偽造医薬品、知的所有権 (IP)・法令に対する中国の管理体制
  • インドへのアウトソーシング
    • イントロダクション
    • インド国内の創薬サービス
    • インド国内での知的所有権・法令の取り扱い
    • FDA (米国食品医薬品局) のインドオフィス
  • 東欧諸国へのアウトソーシング
    • イントロダクション
    • 東欧諸国のCRO

創薬アウトソーシング市場

  • 概要
  • 創薬アウトソーシング市場
    • 市場の現状と将来予測
  • セグメント別の市場分析
    • 化学研究サービス市場
    • 生物学研究サービス市場
    • 高スループット・スクリーニング・サービス市場
    • リード化合物最適化サービス市場
  • 創薬受託市場の競合企業
    • 近年の企業買収の動き
  • オープンイノベーション・モデルの進化による、創薬分野への関心増大
    • 教育機関とCROとの連携
    • 製薬/バイオテクノロジー業界と教育機関との連携
    • CRO相互間での連携
  • 市場成長:創薬サービス企業の海外進出と規模拡大
  • 人工知能 (AI) が今後、創薬分野にも進出するのか?
    • EvotecのAI市場への進出 (企業買収)
    • 製薬企業とAI企業との協業

企業プロファイル

  • Albany Molecular Research, Inc.
    • 沿革、業務分野
    • 創薬サービス
  • Aptuit (Evotec AGの社内部門)
  • Asclepia MedChem Solutions
  • Asinex Ltd.
  • AsisChem Inc.
  • Aurelia Bioscience Ltd
  • Axxam SpA
  • BioDuro
  • Charles River Laboratories, Inc.
  • Charnwood Molecular
  • ChemBridge Corp.
  • Chemical Diversity Inc. (ChemDiv)
  • ChemPartner Co., Ltd., (ShangPharma の子会社)
  • Covance Inc. (Laboratory Corporation of America)
  • CreaGen Biosciences, Inc.
  • Crown Bioscience
  • Cyprotex PLC (Evotec AG の子会社)
  • Domainex
  • Enamine Ltd.
  • Evotec AG
  • Exelgen Discovery
  • GVK Biosciences Private Limited (GVK Bio)
  • GenScript USA Inc.
  • Graffinity Pharmaceuticals GmbH (NovAliX S.A.S の子会社)
  • HitGen Ltd.
  • Hutchison MediPharma, Ltd.
  • Jubilant Biosys Ltd. (JBL), (Jubilant Life Sciences Ltd. の子会社)
  • Nanosyn, Inc.
  • Olon Ricerca Biosciences
  • Pharmaron, Inc.
  • Selcia Limited
  • Selvita S.A.
  • Shanghai Medicilon, Inc.
  • Sundia MediTech Company, Ltd.
  • Sygnature Discovery Limited
  • TCG Lifesciences Pvt Ltd.
  • Viva Biotech, Ltd.
  • WuXi AppTec Co. Ltd.

付録:分析対象企業一覧

  • 企業の名称・住所 (全312社分)
目次
Product Code: KLI15622501

What's happening in the drug discovery market? How much are pharma companies outsourcing? What parts of the process are seeing volume by CROS? What's happening in China and Eastern Europe? Which companies are in leadership in the market?

In eight editions, Kalorama Information's report, Outsourcing in Drug Discovery, has provided answers to these questions and more. As the pharmaceutical industry seeks to boost production recover from a lack of blockbusters, and patients and providers demand effective biotherapies, the race to discover new drugs is more. Kalorama provides information unavailable from any other source, the result of interviews with companies and experts, as well as economic research from Kalorama's proprietary database.

This report, Outsourcing in Drug Discovery, 8th Edition, contains 2017 market size estimates and 2022 forecasts for 21 different parts of the process that might be outsourced, including:

  • Chemistry Services
  • Building Blocks
  • Compound Synthesis
  • Libraries
  • Process Research
  • Biology Services
  • Protein Expression
  • Structural Analysis
  • Target Validation
  • Pathways Analysis
  • Screening Services
  • Assay Development
  • Primary Screening
  • Secondary Screening
  • Lead Optimization
  • Early ADMET
  • Analogues Creation
  • Computational Support
  • Other Services

For each of these categories, market size is provided and forecasts are given to 2022. The drug discovery process is long, arduous and costly, which has driven outsourcing in this field. The first phase is discovery of a lead compound, a molecule that affects biological function by binding to a target protein or nucleic acid in a way that is useful for treatment of disease. The process by which molecules are identified for their therapeutic value involves synthesis and analysis of many derivatives of the original leads. There are several steps in the drug discovery process including hit confirmation, lead generation, lead optimization, and other studies. Drug discovery is a high-cost, risky business because only a fraction of the therapeutic targets selected for study will actually yield products that achieve regulatory approval by the Food & Drug Administration (FDA).

Since the last edition of Kalorama's report on the outsourcing of discovery of novel compounds in the pharmaceutical industry, the industry has seen dramatic change. Pharmaceutical companies facing cutbacks in R&D budgets and new demands for novel products need to outsource aspects of their operations. Core functions once kept in-house such as the discovery of potential new drugs are now commonly outsourced.

Kalorama Information's Outsourcing in Drug Discovery captures this trend, offering unparalleled coverage of the drug discovery outsourcing market. It presents viewpoints from both customers and suppliers. Segments, size, and growth of the market are presented. The trend toward the increased use of offshore suppliers in China, India, Russia and Eastern Europe is covered in detail. The report also provides profiles of 23 suppliers, representative of those active in this market.

Featuring market data and forecasts, the report covers issues such as:

  • Current outsourcing in drug discovery market size and future forecast
  • R&D scale-backs at major companies
  • The fastest-growing services for outsourcers
  • Logistics, IP, regulatory and other issues in China, India and Eastern Europe
  • Common discovery outsourcing pitfalls and how companies overcame them
  • What factors should a client consider when deciding whether to do a project in-house or outsource it?
  • The choice of a domestic outsourcing partner, or an overseas supplier?
  • Best practices when working with a CRO
  • Strategic vs. tactical outsourcing models

This report provides an in depth look into the trends that have shaped the drug discovery outsourcing market today, and details the current and future global market. The report also profiles companies in the market, including the following:

  • Albany Molecular Research, Inc.
  • Aptuit, a Division of Evotec AG
  • Asclepia MedChem Solutions
  • Asinex Ltd.
  • AsisChem Inc.
  • Aurelia Bioscience Ltd
  • Axxam SpA
  • BioDuro
  • Charles River Laboratories, Inc.
  • Charnwood Molecular
  • ChemBridge Corp.
  • Chemical Diversity Inc. (ChemDiv)
  • ChemPartner Co., Ltd., subsidiary of ShangPharma
  • Covance Inc. (Laboratory Corporation of America)
  • CreaGen Biosciences, Inc.
  • Crown Bioscience
  • Cyprotex PLC, an Evotec AG Company
  • Domainex
  • Enamine Ltd.
  • Evotec AG
  • Exelgen Discovery
  • GVK Biosciences Private Limited (GVK Bio)
  • GenScript USA Inc.
  • Graffinity Pharmaceuticals GmbH (subsidiary of NovAliX S.A.S)
  • HitGen Ltd.
  • Hutchison MediPharma, Ltd.
  • Jubilant Biosys Ltd. (JBL), a subsidiary of Jubilant Life Sciences Ltd.
  • Nanosyn, Inc.
  • Olon Ricerca Biosciences
  • Pharmaron, Inc.
  • Selcia Limited
  • Selvita S.A.
  • Shanghai Medicilon, Inc.
  • Sundia MediTech Company, Ltd.
  • Sygnature Discovery Limited
  • TCG Lifesciences Pvt Ltd.
  • Viva Biotech, Ltd.
  • WuXi AppTec Co. Ltd

Table of Contents

Executive Summary

  • Overview
    • Table Drug Discovery Timeline: Research to Viable Product to Commercialization
  • Scope and Methodology
  • Introduction
    • Pharmaceutical Industry Challenges
    • Number of New Molecular Entities (NMEs) and Biologics License Approved (BLAs) Approved
      • Table Number of New Molecular Entities (NMEs) and Biologics License Approved (BLAs) That the US FDA Center for Drug Evaluation and Research (CDER) Approved between 1993-2016
    • R&D Spending
      • Table Domestic R&D and R&D Abroad, PhRMA Member Companies: 1995-2016 ($ billion)
  • The Drug Discovery Process
    • Table The Drug Discovery Process
    • Accelerating the Drug Discovery Process
    • Bottlenecks within the Drug Discovery Process
  • Outsourcing to Increase Efficiency
    • Table Drug Discovery Processes Frequently Outsourced
  • Outsourcing Drug Discovery
    • The Outsourcing Decision
    • Developing an Outsourcing Plan
  • Contract Research Organizations
    • Strategic Versus Tactical Outsourcing Model
    • A New Model Emerging: Insourcing
    • Effective Communication is Essential
    • Mitigating the Challenges of Protecting IP Rights
  • Offshoring Contract Drug Discovery
    • Factors to Consider in Offshore Outsourcing
    • Benefits of Global Outsourcing
    • Concerns about Global Outsourcing
  • Outsourcing to China
    • Chinese Contract Research Organizations
    • FDA Offices in China
  • Outsourcing to India
    • Drug Discovery Services in India
  • Outsourcing to Eastern Europe
  • Drug Discovery Outsourcing Market
    • Current Market and Forecast
      • Table Global Drug Discovery Outsourcing Market, 2012-2022 ($ billion)
    • Market Analysis by Segment
      • Table Market Share Drug Discovery Market Segments, 2018 (%; Lead Optimization, Chemistry Services, Biology Services, HTS)

Introduction to Outsourcing Drug Discovery

  • Background
    • Number of New Molecular Entities (NMEs) and Biologics License Approved (BLAs) Approved
      • Table Number of New Molecular Entities (NMEs) and Biologics License Approved (BLAs) That the US FDA Center for Drug Evaluation and Research (CDER) Approved between 1993-2016
    • R&D Spending
      • Table Domestic R&D and R&D Abroad, PhRMA Member Companies: 1995-2016 ($ billion)
    • Ramping up the Pipelines
  • Outsourcing Drug Discovery
  • The Outsourcing Decision
    • Developing an Outsourcing Plan
    • Decision Criteria
  • Factors to Consider in Offshore Outsourcing
    • Benefits of Global Outsourcing
    • Concerns about Global Outsourcing
  • Selecting a Contract Research Organization
    • Introduction
    • Choosing the Right CRO
  • Global Outsourcing
    • Table Selection of Global Drug Discovery Outsourcing Collaborations

The Drug Discovery Process

  • Introduction
    • Table The Drug Discovery Process
    • Discovery Stages
  • Accelerating the Drug Discovery Process
    • Technologies Utilized in Drug Discovery
      • Table Drug Discovery Timeline: Research to Viable Product to Commercialization
      • Table Bioinformatics/Pharmacogenomics
      • Table Causes of New Drug Attrition (%; Unsuitable Bioavailability Profile, Toxicity, Commercial Setbacks, Other)
    • Bottlenecks within the Drug Discovery Process
  • Outsourcing to Increase Efficiency
    • Table Drug Discovery Processes Frequently Outsourced
  • Outsourcing to Access Novel Technologies
    • Bioinformatics
    • Lab-on-a-chip: Microfluidics in Drug Discovery
      • Table Bioinformatics as a Central Hub

Outsourcing Drug Discovery

  • Overview
    • The Traditional Drug Discovery Model Is Changing
      • Table A Selection of R&D Facilities Closed or Reduced in Size between 2010 and 2017
  • Outsourcing Drug Discovery Useful Core Management Tool
  • Contract Research Organizations
    • Introduction
    • Role of a CRO
    • Outsourcing Models
    • Effective Communication Is Essential for a Successful Partnership
    • Mitigating the Challenges of Protecting IP Rights
  • Outsourcing Contract Drug Discovery Offshore
    • Introduction
    • Robust Growth of Outsourcing Drug Discovery in Asia
    • Evolution of Contract Drug Discovery in Asia
  • Outsourcing to China
    • Introduction
    • Multi-National Pharmaceutical Companies Establish Research and Development Facilities in China
    • Chinese Contract Research Organizations
      • Table A Selection of Chinese Drug Discovery CROs
    • WuXi AppTec, China's Largest CRO
    • First Chinese CRO Alliance
    • FDA Offices in China
    • China's Management of Counterfeit Pharmaceuticals, IP Rights and Laws
  • Outsourcing to India
    • Introduction
    • Drug Discovery Services in India
      • Table A Selection of Indian Drug Discovery CROs
    • India's Handling of IP Rights and Laws
    • FDA Offices in India
  • Outsourcing to Eastern Europe
    • Introduction
    • Eastern European CROs
      • Table A Selection of Major CROs Operating in Eastern Europe

Drug Discovery Outsourcing Market

  • Overview
  • Drug Discovery Outsourcing Market
    • Current Market and Forecast
      • Table Global Drug Discovery Outsourcing Market, 2012-2022 ($ billion)
      • Table Contract Drug Discovery Services, by Market Segment, 2012-2022 ($ billion)
  • Market Analysis by Segment
    • Table Market Share Drug Discovery Market Segments, 2018 (%; Lead Optimization, Chemistry Services, Biology Services, HTS)
    • Chemistry Services Market
      • Table Chemistry Services Market: Revenues, Annual Growth, and Share of Outsourced Drug Discovery Market, 2012-2022 ($ billion)
      • Table Chemistry Market Revenue by: Building Blocks, Compound Synthesis, Libraries, Process Research, and Other Services, 2018 ($ billion)
    • Biology Services Market
      • Table Biology Services Market: Revenues, Annual Growth, and Share of Outsourced Drug Discovery Market, 2012-2022 ($ billion)
      • Table Biology Market Revenue by: Protein Expression, Structural Analysis, Target Validation, Pathways Analysis, and Other Service, 2018 ($ billion)
    • High Throughput Screening Services Market
      • Table HTS Services Market: Revenues, Annual Growth, and Share of Outsourced Drug Discovery Market, 2012-2022 ($ billion)
      • Table HTS Screening Services Market: Assay Development, Primary Screening, Secondary Screening, 2018 ($ billion)
    • Lead Optimization Services Market
      • Table Lead Optimization Services Market: Revenues, Annual Growth, and Share of Outsourced Drug Discovery Market, 2012-2022 ($ billion)
      • Table Lead Optimization Services Market: Early ADMET/Tox, Create Analogues, Computational Support, and Other Services, 2018 ($ billion)
  • Contract Drug Discovery Competitors
    • Recent Acquisitions in Drug Discovery Outsourcing, 2014-2016
  • The Evolving Open-Innovation Model Gaining Traction in Drug Discovery
    • Alliances between Academic Organizations and CROs
      • Table A Selection of Collaborations between CROs and Academic Organizations
    • Alliances between the Pharmaceutical/Biotechnology Industries and Academia
      • Table Alliances between Pharma/Biotech and Academia
    • Alliances between CROs
      • Table A Selection of Alliances between CROs
  • Market Growth Expanding Global Reach and Scale of Drug Discovery Services
    • Table Global Expansion of Contract Drug Discovery Services East and West
  • Is Artificial Intelligence (AI) the Future of Drug Discovery?
    • Evotec Buys into AI
    • Pharmaceutical Companies Collaborate with AI Companies

Competitor Profiles

  • Albany Molecular Research, Inc.
    • History and Lines of Business
    • Drug Discovery Services
  • Aptuit, a Division of Evotec AG
    • History and Lines of Business
    • Drug Discovery Services
  • Asclepia MedChem Solutions
    • History and Lines of Business
    • Drug Discovery Services
  • Asinex Ltd.
    • History and Lines of Business
    • Drug Discovery Services
  • AsisChem Inc.
    • History and Lines of Business
    • Drug Discovery Services
  • Aurelia Bioscience Ltd
    • History and Lines of Business
    • Drug Discovery Services
  • Axxam SpA
    • History and Lines of Business
    • Drug Discovery Services
  • BioDuro
    • History and Lines of Business
    • Drug Discovery Services
  • Charles River Laboratories, Inc.
    • History and Lines of Business
    • Drug Discovery Services
  • Charnwood Molecular
    • History and Background
    • Drug Discovery Services
  • ChemBridge Corp.
    • History and Background
    • Drug Discovery Services
  • Chemical Diversity Inc. (ChemDiv)
    • History and Lines of Business
    • Drug Discovery Services
  • ChemPartner Co., Ltd., subsidiary of ShangPharma
    • History and Lines of Business
    • Drug Discovery Services
  • Covance Inc. (Laboratory Corporation of America)
    • History and Lines of Business
    • Drug Discovery Services
  • CreaGen Biosciences, Inc.
    • History and Lines of Business
    • Drug Discovery Services
  • Crown Bioscience
    • History and Lines of Business
    • Drug Discovery Services
  • Cyprotex PLC, an Evotec AG Company
    • History and Line of Business
    • Drug Discovery Services
  • Domainex
    • History and Lines of Business
    • Drug Discovery Services
  • Enamine Ltd.
    • History and Lines of Business
    • Drug Discovery Services
  • Evotec AG
    • History and Lines of Business
    • Drug Discovery Services
  • Exelgen Discovery
    • History and Lines of Business
    • Drug Discovery Services
  • GVK Biosciences Private Limited (GVK Bio)
    • History and Lines of Business
    • Drug Discovery Services
  • GenScript USA Inc.
    • History and Lines of Business
    • Drug Discovery Services
  • Graffinity Pharmaceuticals GmbH (subsidiary of NovAliX S.A.S)
    • History and Lines of Business
    • Drug Discovery Services
  • HitGen Ltd.
    • History and Lines of Business
    • Drug Discovery Services
  • Hutchison MediPharma, Ltd.
    • History and Lines of Business
    • Drug Discovery Services
  • Jubilant Biosys Ltd. (JBL), a subsidiary of Jubilant Life Sciences Ltd.
    • History and Lines of Business
    • Drug Discovery Services
  • Nanosyn, Inc.
    • History and Lines of Business
    • Drug Discovery Services
  • Olon Ricerca Biosciences
    • History and Lines of Business
    • Drug Discovery Services
  • Pharmaron, Inc.
    • History and Lines of Business
    • Drug Discovery Services
  • Selcia Limited
    • History and Lines of Business
    • Drug Discovery Services
  • Selvita S.A.
    • History and Lines of Business
    • Drug Discovery Services
  • Shanghai Medicilon, Inc.
    • History and Lines of Business
    • Drug Discovery Services
  • Sundia MediTech Company, Ltd.
    • History and Lines of Business
    • Drug Discovery Services
  • Sygnature Discovery Limited
    • History and Lines of Business
    • Drug Discovery Services
  • TCG Lifesciences Pvt Ltd.
    • History and Lines of Business
    • Drug Discovery Services
  • Viva Biotech, Ltd.
    • History and Lines of Business
    • Drug Discovery Services
  • WuXi AppTec Co. Ltd.
    • History and Lines of Business
    • Drug Discovery Services

Appendix: Company Names and Addresses

  • Company Names and Addresses
    • 2-y Chem, Ltd.
    • Abgenix
    • AbMax Biotechnology
    • Absorption Systems
    • Acesys Pharmatech
    • Actimus Biosciences Pvt. Ltd.
    • ActivX Biosciences
    • Advinus Therapeutics Pvt. Ltd.
    • Advinus Therapeutics Ltd.
    • Agios Pharmaceuticals
    • Albany Molecular Research, Inc.
    • Advinus Therapeutics Ltd.
    • Affinium Pharmaceuticals
    • Albermarle Corp.
    • Alphora Research Inc.
    • Ambit Biosciences Corp.
    • Amgen, Inc.
    • Antabio Pharmaceutical
    • Apredica
    • Aptuit, LLC
    • Asclepia
    • Asinex Ltd.
    • Asinex
    • AsisChem, Inc.
    • Astex Therapeutics
    • AstraZeneca
    • Asymchem Laboratories Co., Ltd.
    • Asymchem Laboratories Inc.
    • Aurigene Discovery Technologies Ltd.
    • Aurelia Bioscience Ltd
    • Aurigene Discovery Technologies Limited
    • Axxam SpA
    • Berg Health
    • BioAnaLab Limited
    • BioBlocks Incorporated
    • Biocentrum Cell Laboratories, a division of Selvita S.A.
    • Biocius Life Sciences, Inc.
    • BioDuro, Inc.
    • BioDuro, Inc.
    • Biogen Idec
    • Biolog, Inc.
    • Bioneeds
    • Bionomics Ltd.
    • BioReliance Corporation
    • Biovays SAS
    • BioVisioN AG
    • Boehringer Ingelheim Pharmaceuticals, Inc.
    • British Columbia Cancer Agency
    • Caliper Life Sciences
    • Cambridge Antibody
    • Cambridge Major Laboratories, Inc
    • Cantab Biopharmaceuticals Ltd,
    • CarysBio Holding Ltd.
    • Cayman Chemical
    • Celera Genomics
    • CellCentric Ltd.
    • Cell & Molecular Technologies
    • Cellzome AG
    • Cellzome (UK)
    • Cetek Corp.
    • Eurofins Advinus Limited
    • Charles River Laboratories, Inc.
    • Charnwood Molecular
    • Chemizon, Inc.
    • ChemPartner Co., Ltd.
    • Chiesi Farmaceutici SP
    • Charnwood Molecular
    • Chembiotek
    • ChemBridge Corp.
    • ChemDiv
    • Chemizon, Inc.
    • Chemizon Ltd
    • ChemModeling, LLC
    • Chemotargets SL
    • ChemOvation Ltd.
    • ChemShop BV
    • ComGenex Inc.
    • Compugen
    • Covance, Inc
    • CreaGen Biosciences, Inc.
    • Creative BioStructure
    • Cresset Drug Discovery
    • Crown Bioscience Inc.
    • Crown Bioscience Inc.
    • CuraGen Corp.
    • Cychem, Inc.
    • Cyprotex PLC
    • Dalton Chemical Laboratories Inc.
    • Debiopharm International SA
    • Deltagen
    • DiscoveRx Corporation
    • DiscoveryBioMed, Inc.
    • Domainex
    • DoubleTwist Inc.
    • Dr. Reddy's Laboratories Ltd.
    • Dr. Reddy's Laboratories, Inc.
    • Dynogen Pharmaceuticals, Inc.
    • EM Industries, Inc.
    • Elan Pharmaceuticals
    • ElexoPharm GmbH
    • Ely Lilly and Company
    • Emerald Biostructures
    • Enamine LLC
    • Enamine Ltd.
    • Endo Pharmaceutical
    • Ensemble Discovery Corporation
    • Epiclone, L.A.
    • Evolus Inc.
    • Evotec AG
    • Evotec AG
    • Evotec (Asia) Pte. Ltd.
    • Evotec (India) Private Limited
    • Exelgen Discovery
    • Exscientia
    • ExonHit Therapeutics SA
    • ExSAR
    • Flourous Technologies
    • GPC Biotech AG
    • GVK Biosciences Private Limited
    • GVK Biosciences Private Limited
    • GVK Biosciences Private Limited
    • Galapagos NV
    • GeneFormatics Inc.
    • Gene Logic Inc.
    • GenScript USA Inc.
    • GenScript Biotech Corporation
    • GlaxoSmithKline
    • Genentech, Inc.
    • Geneome Therapeutics
    • GeneProt
    • Genome BioSciences, Inc.
    • Genomics Collaborative Inc.
    • Genops Bioinformatics Inc.
    • GenOway
    • Insilico
    • GenScript USA Inc.
    • GenScript USA Inc.,
    • GenScript
    • Genta, Inc.
    • Genezyme Corporation
    • Gilead Sciences
    • Glaucus Proteomics BV
    • Graffinity Pharmaceuticals GmbH
    • Grünenthal Group
    • HD Biosciences, Inc.
    • HitGen Ltd.
    • Human Genome Sciences
    • Hutchison MediPharma Limited
    • Hybrigen
    • Hybrigenics SA
    • Icagen, Inc.
    • Iconix Pharmaceuticals, Inc.
    • ICOS Corporation
    • ID Business Solutions Ltd.
    • Indus Bioscience
    • Informax Inc.
    • iNovacia
    • Inpharmatica
    • InterChem
    • iThemba Pharma
    • Johnson Matthey Pharma Services
    • J-Star Research
    • Janssen Pharma
    • Johnson & Johnson
    • Jubilant Life Sciences Ltd.
    • Julilant Biosys Ltd.
    • Julilant Discovery Center (Noida)
    • Kalexsyn
    • Kendle International
    • Key Organics Ltd.
    • Laboratory Corporation of America Holdings
    • Lancaster Laboratories
    • Lark Technologies, Inc.
    • Laxai Corporation
    • Laxai Avanti Life Sciences
    • Lexicon Genetics Inc.
    • Life Chemicals Inc.
    • Linden Bioscience
    • Ligand Pharmaceuticals, Inc.
    • Magellan Laboratories
    • Maybridge plc
    • Medarex
    • Medicilon, Inc.
    • Medicilon, Inc.
    • Merck KGaA
    • Merrimack Pharmaceuticals, Inc.
    • Metabometrix Ltd.
    • MerLion Pharmaceuticals Pte Ltd
    • Metabometrix Ltd.
    • Micron Technologies, Inc.
    • Morphochem AG
    • MPI Research
    • Multispan, Inc.
    • Myriad Genetics Inc.
    • Naeja Pharmaceutical Inc.
    • Nanostream, Inc.
    • Nanosyn, Inc.
    • Navigen Pharma
    • NEOMED Institute
    • Neurodegeneration Consortium
    • Nextgen Sciences Ltd.
    • Nicholas Piramal India Limited
    • NiKem Research s.r.l.
    • NitroMed, Inc.
    • Novartis Institute of BioMedical Research
    • Numerate, Inc.
    • Nycomed GmbH
    • OncoDesign SA
    • OpGen
    • Organix Inc.
    • Organomed Corp.
    • Orion Pharmaceuticals
    • Oxford GlycoSciences Plc
    • Pcovery
    • PharmaCore
    • PharmaLink
    • Pharmaron Beijing Co., Ltd.
    • Pharmaron
    • Pharmidex
    • Parexel
    • Peakdale Molecular Ltd.
    • PepTech Corporation
    • Pfizer, Inc.
    • Procter and Gamble Company
    • Pharmaron Beijing Limited Co.
    • Pharmaron, Inc.
    • Pharmaron-Beijing
    • PharmEco
    • Pharmidex
    • Phenomix Corp.
    • Phylos Inc.
    • Polyphor Ltd
    • PD, Inc.
    • PRECOS Ltd.
    • Prestwick Chemical
    • Prestwick Chemical
    • Protein Mechanics, Inc.
    • Proteome Systems Ltd.
    • Proteologics Ltd.
    • ProteoMetrics Inc.
    • Protogene Laboratories Inc.
    • Provid Pharmaceuticals Inc.
    • Purely Proteins
    • Pyxis Discovery
    • Pyxis Discovery
    • Quantum Pharmaceuticals
    • Quintiles Transnational Corp.
    • Regulus Therapeutics
    • Reliance Life Sciences
    • Renovis
    • Rib-X Pharmaceuticals
    • Ricerca, LLC
    • RMC Biosciences, Inc.
    • Roche R&D Center Ltd.
    • Sai Advantium Pharma Ltd.
    • Scottish Biomedical
    • Scynexis, Inc.
    • Selcia Limited
    • SelciaWest
    • Selvita S.A.
    • Sequenom
    • Sequitur, Inc.
    • Shanghai GenMed
    • Shanghai Genomics
    • Shanghai LeadChem, subsidiary of Shanghai LeadDiscovery Pharmaceutical, Ltd.
    • Shanghai LeadDiscovery Pharmaceutical, Ltd.
    • Shanghai Medicilon
    • Shanghai United PharmaTech
    • Shasun Pharmaceuticals Ltd.
    • Shenogen Pharma Group
    • Shionogi & Co., Ltd.
    • Shire plc
    • Signature BioScience Inc.
    • Simulations Plus, Inc.
    • SomaLogic Inc.
    • Southern Research Institute
    • SPECS
    • Spectrum Bioscience
    • SRI Biosciences
    • Structural Bioinformatics, Inc.
    • Structural GenomiX
    • Sun Pharma Advanced Research Company
    • Sundia MediTech Company, Ltd.
    • Sundia MediTech Company, Ltd.
    • Sunesis Pharmaceuticals
    • Suven Life Sciences Ltd
    • Sygnature Discovery Limited
    • Synaptica Ltd.
    • Syngene International Pvt. Ltd.
    • Syngene International Pvt. Ltd.
    • Syrrx
    • TCG Lifesciences Limited
    • Targeted Molecules Corp.
    • Torcan Chemical Ltd.
    • Transform Pharmaceuticals Inc.
    • Venturepharm Group
    • VVertex Pharmaceuticals Inc.
    • Viva Biotech Ltd.
    • Vivo Biosciences Inc.
    • WIL Research U.S.
    • WIL Research Europe - Schaijk
    • WIL Research Europe
    • WIL Research UK
    • WuXI AppTec Co. Ltd.
    • WuXi AppTec, Inc.
    • WuXi AppTec, Inc.
    • WuXi AppTec, Inc.
    • Xencor
    • Yangtze River Pharmacy Group Co
    • Zensun Sci & Tech Co., Ltd
    • ZoBio BV
    • Zygogen, LLC
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