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市場調査レポート
商品コード
1173206
アトピー性皮膚炎治療薬の世界市場規模、シェア、産業動向分析レポート:投与経路別、クラス別(生物製剤、カルシニューリン阻害剤、コルチコステロイド、PDE4阻害剤)、地域別展望および予測、2022年~2028年Global Atopic Dermatitis Drugs Market Size, Share & Industry Trends Analysis Report By Route of Administration, By Class (Biologics, Calcineurin Inhibitors, Corticosteroids, PDE4 Inhibitors), By Regional Outlook and Forecast, 2022 - 2028 |
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アトピー性皮膚炎治療薬の世界市場規模、シェア、産業動向分析レポート:投与経路別、クラス別(生物製剤、カルシニューリン阻害剤、コルチコステロイド、PDE4阻害剤)、地域別展望および予測、2022年~2028年 |
出版日: 2022年11月30日
発行: KBV Research
ページ情報: 英文 175 Pages
納期: 即納可能
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アトピー性皮膚炎治療薬の世界市場規模は、2028年までに220億米ドルに達し、予測期間中にCAGR 9.2%の市場成長率で上昇すると予測されています。
アトピー性皮膚炎は、年齢を問わず発症しますが、通常は小児期に初めて発症し、その重症度は時間と共に変化します。1歳未満の幼児では、体の多くの部分に影響が出る可能性があります。膝や肘の内側は、子供の年齢とともに最も頻繁に影響を受ける部分です。大人では、手足に多く見られます。
患部を掻くと症状が悪化し、掻いている人は皮膚感染症になる可能性が高くなります。アトピー性皮膚炎は、喘息や花粉症につながることも多いです。病気を悪化させるものを避ける、定期的な入浴と保湿クリームの使用、症状が出たときのステロイドクリームの使用、かゆみを抑える薬などの治療が必要です。
ウールの衣服、石鹸、香料、ほこり、塩素、タバコの煙などは、頻繁に悪化させるいくつかのものです。人によっては、光線療法が有効な場合もあります。他の治療が無効な場合は、ステロイドの錠剤やカルシニューリン阻害剤をベースにしたローションが採用されることがあります。細菌感染がある場合は、抗生物質(経口または局所)の投与が必要です。食物アレルギーが検出された場合のみ、食事療法が必要となります。
COVID-19の影響分析
コロナウイルスは、社会的な交流から医療や外の世界の見方に至るまで、あらゆるものを混乱させ、世界の規模で人々の生活に問題を引き起こしています。あらゆる産業で、パンデミックの流行による利益や生産高の減少が起きています。しかし、アトピー性皮膚炎の治療市場は、患者の通院が不規則であることから、大きな影響が予想されます。このような状況下でも、患者の大半は医師の診察を受けずに一般的な治療や追加的な治療を受けることができるため、テレデマトロジーは成長を続けているのです。
市場の成長要因
生物学的製剤の需要拡大
皮膚科疾患、特にアトピー性皮膚炎の治療は、皮膚科における生物学的製剤の使用により変化してきました。生物学的製剤はアトピー性皮膚炎に対して良好な反応を示し、全体的な生活の質を向上させることができました。その結果、現在ではアトピー性皮膚炎に対する生物学的製剤の治療に対する需要が高まっています。今後数年間は、おそらくこのパターンが続くと思われます。アトピー性皮膚炎の治療薬として承認されている生物学的製剤は、今のところ1つだけです。現在、多くの製品が第II相臨床試験を実施中であり、おそらく近いうちに承認されるであろう。
アトピー性皮膚炎の有病率の上昇
アトピー性皮膚炎治療薬の市場を牽引する主な要因は、世界のアトピー性皮膚炎患者の増加であると予想されます。多くの人々がアトピー性皮膚炎に苦しんでおり、今後数年間でさらに増加すると予想されています。アトピー性皮膚炎は、地理的条件、気候条件、社会経済水準、ライフスタイル、年齢、性別、遺伝、個人の行動などが、世界中の皮膚科疾患の有病率に影響を及ぼしていると言われています。アトピー性皮膚炎は、日常的にアレルギーと付き合わなければなりません。
市場抑制要因
局所用ステロイドの副作用
4週間未満のステロイド外用薬治療は、リスクもトラブルもないことが多いです。ステロイド外用剤の長期使用や、刺激の強いステロイドの短時間投与を頻繁に繰り返すと、問題が生じることがあります。主な問題は、強力なステロイドの長期使用です。軽度のステロイド外用剤では、ほとんど副作用はありません。ステロイド外用剤には、局所的な副作用と全身的な副作用があります。全身性とは、個人全体に影響する問題で、局所性とは、皮膚の特定の部分に影響する問題です。
クラスの展望
クラスに基づいて、アトピー性皮膚炎治療薬市場は、コルチコステロイド、カルシニューリン阻害剤、PDE4阻害剤、生物製剤、その他に区分されます。2021年、副腎皮質ホルモンセグメントは、アトピー性皮膚炎治療薬市場においてかなりの収益シェアを獲得しています。炎症性腸疾患、発疹、喘息などの多くの症状は、コルチゾン、ヒドロコルチゾン、プレドニゾンなどのコルチコステロイド薬でうまく治療することができます。
投与経路の展望
アトピー性皮膚炎治療薬市場は、投与経路に基づき、外用剤、注射剤、経口剤に細分化されます。2021年、アトピー性皮膚炎治療薬市場では、注射剤が最大の収益シェアを占めています。これは、デュピルマブのような注射剤の人気が高まっているためです。Tofacitinibとruxolitinibは、臨床試験で研究されている他の注射用生物製剤です。近い将来、生物学的製剤はADの治療状況を変化させると予想されています。
地域別の展望
地域別に見ると、アトピー性皮膚炎治療薬市場は、北米、欧州、アジア太平洋、LAMEAで分析されています。2021年には、北米地域が最も高い収益シェアを獲得し、アトピー性皮膚炎治療薬市場をリードしました。確立された研究開発インフラと親切な償還規則が利用可能であることが、この地域の持続的な優位性に寄与する2つの主要因です。また、この分野の研究の急速な進展に伴い、規制や償還の環境も常に変化しています。
市場参入企業がとる主な戦略は買収です。カーディナルマトリックスで提示された分析によると、アトピー性皮膚炎治療薬市場では、ファイザーとノバルティスAGが先行しています。AbbVie, Inc.、Sanofi SA、Regeneron Pharmaceuticals Inc.などの企業は、アトピー性皮膚炎治療薬市場における主要な革新者の一部です。
List of Figures
The Global Atopic Dermatitis Drugs Market size is expected to reach $22 billion by 2028, rising at a market growth of 9.2% CAGR during the forecast period.
Eczema, commonly referred to as atopic dermatitis, is a skin ailment that affects the skin and results in itching, dryness, and inflammation. The illness has a potential for chronicity and occasionally flares up and spreads. Drugs for atopic dermatitis, such as atopic eczema steroids, are utilized to treat eczema, lessen itching, and treat other atopic dermatitis-related disorders.
Atopic dermatitis patients run the risk of acquiring asthma, hay fever, and food allergies. Regular moisturizing and other skin care practices help reduce itching and stop future outbreaks. Medicated lotions or ointments may also be used during treatment. It causes skin that is scratchy, red, swollen, and cracked. The damaged sites may leak a clear fluid that thickens over time.
Although the disorder can strike at any age, it usually first manifests in childhood and varies in severity throughout time. Much of the body may be impacted in youngsters under the age of one year. The areas on the inside of the knees and elbows are most frequently affected as kids age. Adults are more frequently afflicted in the hands and feet.
Scratching the affected regions makes the symptoms worse, and individuals who are scratching have a higher chance of developing skin infections. Atopic dermatitis frequently leads to the development of asthma or hay fever. Avoiding things that aggravate the illness, regular bathing followed by the use of moisturizing cream, using steroid creams when flare-ups happen, and drugs to relieve itching are all part of the treatment.
Wool garments, soaps, fragrances, dust, chlorine, and cigarette smoke are a few things that frequently aggravate it. Some people may benefit from phototherapy. If other treatments are ineffective, steroid tablets or lotions based on calcineurin inhibitors may occasionally be employed. If a bacterial infection manifests, antibiotics (by mouth or topically) could be required. Only if food allergies are detected are dietary modifications required.
COVID-19 Impact Analysis
The coronavirus is still creating trouble in people's lives on a worldwide scale, disrupting everything from social interactions to how they seek medical care and see the outside world. Every industry has experienced a profit or output decrease as a result of the pandemic epidemic. However, the market for treating atopic dermatitis has anticipated a substantial impact because of the irregularity of hospital visits by patients. Teledermatology has grown during the crisis when the majority of patients continue to receive generalized care and/or additional consultative therapies without seeing a doctor in person.
Market Growth Factors
Growing Demand For Biologics
The treatment of dermatological disorders, particularly atopic dermatitis, has changed as a result of the use of biologic drugs in dermatology. Biologics have demonstrated a good response to atopic dermatitis, improving the overall quality of life. As a result, there is now a greater demand for biologic treatments for atopic dermatitis. In the upcoming several years, this pattern is probably going to continue. For the time being, only one biologic product has been authorized for the treatment of atopic dermatitis. Many more are currently through phase II clinical studies and will probably be approved soon.
Rising Prevalence Of Atopic Dermatitis
The increasing prevalence of atopic dermatitis medications around the world is anticipated to be the main factor driving the market for atopic dermatitis medications. A large number of people suffer with atopic dermatitis which is expected to rise even more in upcoming years. Geographical location, climatic circumstances, socioeconomic level, lifestyle, age, gender, inheritance, and individual behaviors all have an impact on the prevalence of dermatological problems around the world. An individual with atopic dermatitis must deal with allergies on a daily basis.
Market Restraining Factors
Side Effects Of Topical Steroids
Topical steroid treatments lasting fewer than four weeks are often risk-free and trouble-free. Long-term topical steroid use or frequent repetition of short doses of harsher steroids may cause issues. The primary issue is the prolonged usage of potent steroids. Mild topical steroids rarely have side effects. Topical steroids may have local or systemic side effects. Systemic refers to an issue that affects the entire individual, whereas local refers to that particular area of skin.
Class Outlook
Based on class, the atopic dermatitis drugs market is segmented into corticosteroids, calcineurin inhibitors, PDE4 inhibitors, biologics and others. In 2021, the corticosteroids segment acquired a substantial revenue share in the atopic dermatitis drugs market. Many conditions, such as inflammatory bowel disease, rashes, and asthma, can be successfully treated with corticosteroid medications, such as cortisone, hydrocortisone, and prednisone.
Route Of Administration Outlook
On the basis of route of administration, the atopic dermatitis drugs market is fragmented into topical, injectable and oral. In 2021, the injectable segment held the largest revenue share in the atopic dermatitis drugs market. This is due to the rising popularity of injectable drugs like Dupilumab. Tofacitinib and ruxolitinib are other injectable biologics being studied in clinical trials. In the near future, biologics are anticipated to alter the therapy landscape for AD.
Regional Outlook
Region wise, the atopic dermatitis drugs market is analyzed across North America, Europe, Asia Pacific and LAMEA. In 2021, the North America region led the atopic dermatitis drugs market by generating the highest revenue share. The availability of a well-established R&D infrastructure and kind reimbursement rules are two major factors contributing to the region's sustained dominance. Additionally, the regulatory and reimbursement environment is constantly changing to keep up with the rapid advancement of research in this field.
The major strategies followed by the market participants are Acquisitions. Based on the Analysis presented in the Cardinal matrix; Pfizer, Inc. and Novartis AG are the forerunners in the Atopic Dermatitis Drugs Market. Companies such as AbbVie, Inc., Sanofi SA, Regeneron Pharmaceuticals Inc. are some of the key innovators in Atopic Dermatitis Drugs Market.
The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include Pfizer Inc., Sanofi SA, AbbVie Inc., Galderma S.A., Eli Lilly and Company, Leo Pharma A/S, Regeneron Pharmaceuticals Inc., Otsuka Pharmaceutical Co. Ltd., Novartis AG, and Incyte Corporation.
Recent Strategies Deployed in Atopic Dermatitis Drugs Market
Mergers and Acquisitions:
Oct-2022: Incyte completed the acquisition of Villaris Therapeutics, an asset-centric biopharmaceutical company. This acquisition would complement Incyte's current portfolio, providing Incyte the opportunity to improve treatment options for people with vitiligo, that leverage the expertise established in the dermatology space.
Jun-2022: Pfizer took over ReViral, a privately held, clinical-stage Biopharmaceutical Company. This acquisition further demonstrates Pfizer's commitment to advancing pioneering science both through its in-house expertise and work with leading, innovative companies - with the aim to deliver breakthroughs to patients suffering from severe infectious diseases.
Mar-2022: Pfizer completed the acquisition of Arena Pharmaceuticals, an American biopharmaceutical company. Through this acquisition, Pfizer would add the impressive experience and pipeline of Arena Pharmaceuticals to Pfizer's Inflammation & Immunology therapeutic area, helping the company further its purpose of developing breakthroughs to change the lives of those with immuno-inflammatory diseases.
Jan-2022: Galderma took over ALASTIN Skincare, a specialty aesthetics company. This acquisition aimed at enhancing Galderma's integrated dermatology platform with a comprehensive collection of scientifically-approved products for daily skincare regimens and peri-procedural use. Also, the acquisition would underscore Galderma's commitment to being the partner of choice for aesthetic professionals.
Dec-2021: AbbVie took over Soliton, a medical device company. The acquisition would complement Allergan Aesthetics' portfolio of non-invasive body contouring treatments to include a proven treatment for the appearance of cellulite.
Nov-2021: Sanofi completed the acquisition of Translate Bio, a biotechnology company that specializes in biotechnology, RNA therapeutics, and rare diseases. The acquisition support Sanofi's mRNA Center of Excellence, which plans to explore the potential of enhanced mRNA vaccines & other key areas that includes immunology, oncology, and rare diseases.
Nov-2021: Sanofi took over Kadmon Holdings, which operates as a biopharmaceutical company. This acquisition would strengthen the expansion & growth of the general medicines portfolio.
Jul-2019: LEO Pharma completed the acquisition of Bayer. LEO Pharma advances significantly towards its goal of helping 125 million patients by 2025. With this acquisition, the LEO considerably improve its size in key markets like Austria, Brazil, and South Africa - underlining its ambition to become a global leader in medical dermatology.
Approvals and Trials:
Oct-2022: LEO Pharma got European approval for Adtralza, a drug to treat moderate-to-severe AD in adolescents. The approval would address LEO's relentless commitment to bringing the latest treatment options for those living with atopic dermatitis. This approval enables LEO to address the unmet needs of a broader patient population as it looks forwards to work with key stakeholders across the Europe region.
Jun-2022: Sanofi got FDA approval for Dupixent, a biologic medicine approved to treat moderate-to-severe atopic dermatitis from infancy to adulthood. The approval would enable the availability of Dupixent for young people with the disease.
Jan-2022: Pfizer got FDA approval for CIBINQO, an oral, once-daily, Janus kinase 1 (JAK1) inhibitor. CIBINQO would offer the treatment of adults living with refractory, moderate-to-severe atopic dermatitis (AD) whose disease is not adequately controlled with other systemic drug products. CIBINQO would provide an important latest oral option that would help those who have yet to find relief.
Jan-2022: AbbVie got FDA approval for RINVOQ, a once-daily oral option that can significantly enhance the debilitating itch & skin symptoms of atopic dermatitis. Through this acquisition, AbbVie would continue its efforts to enhance care in this disease state & other chronic, immune-mediated conditions.
Dec-2021: Leo Pharma got FDA approval for Adbry, an eczema drug. The injected antibody drug would address adults and older who don't get proper relief from topical prescription therapies. Adbry would signify important progress in LEO's aim of enhancing the standard of care in medical dermatology.
Sep-2021: Otsuka got FDA approval for Moizerto Ointment, a treatment for atopic dermatitis. Otsuka expects that Moizerto Ointment would serve as the latest treatment option for people having atopic dermatitis in Japan.
Sep-2021: Incyte got FDA approval for Opzelura, a topical JAK inhibitor to treat AD. With this approval, the company looks forward to bringing Opzelura to the patient community and also continuing to explore its potential in other skin diseases.
Market Segments covered in the Report:
By Route of Administration
By Class
By Geography
Companies Profiled
Unique Offerings from KBV Research