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EpiCast Report:潰瘍性大腸炎の疫学的予測

EpiCast Report: Ulcerative Colitis - Epidemiology Forecast to 2025

発行 GlobalData 商品コード 432898
出版日 ページ情報 英文 101 Pages
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EpiCast Report:潰瘍性大腸炎の疫学的予測 EpiCast Report: Ulcerative Colitis - Epidemiology Forecast to 2025
出版日: 2017年01月01日 ページ情報: 英文 101 Pages
概要

当レポートでは、世界の主要7ヶ国(米国・フランス・ドイツ・イタリア・スペイン・英国・日本)における、潰瘍性大腸炎 (UC) の発症状況と今後の見通しについて分析し、潰瘍性大腸炎の特徴共存症や、世界的な発症状況、今後10年間の発症件数・有病者数の動向見通し (未決定性大腸炎 (IC) との比較を含む) などを調査しております。

第1章 目次

第2章 疫学

  • 疾患の背景
  • リスク要因と共存症
  • 世界的な傾向
    • 発症件数
    • 有病者数
  • 予測手法
    • 利用した情報源
    • 予測の前提条件と手法
    • 利用しなかった情報源
  • 潰瘍性大腸炎 (UC) の疫学的予測 (今後11年間分)
    • UCの受診済み発症件数
    • UCの受診済み有病者数
    • UCの未受診の有病者数
    • UC有病者総数
    • IC (未決定性大腸炎) の受診済み発症件数
    • ICの受診済み有病者数
  • 議論
    • 疫学的傾向に関する考察
    • 分析の限界
    • 分析の強み

第3章 付録

図表一覧

目次
Product Code: GDHCER146-16

Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) characterized by long-lasting inflammation and ulcers (sores) in the lining of the digestive tract. In UC, because of an abnormal response of the body's immune system, the lining of the colon becomes inflamed and develops tiny open sores, or ulcers, that produce pus and mucous. This causes abdominal discomfort and frequent emptying of the colon. UC is a type of IBD, not to be confused with irritable bowel syndrome (IBS), a disorder that affects the muscle contractions of the colon and is not characterized by intestinal inflammation.

UC commonly affects teenagers and young adults, and can result in poor development and growth; nonetheless, the disease can also occur in children and older individuals (CCFA, 2016a). Unlike the other form of IBD-Crohn's disease (CD), which has similar symptoms but can occur anywhere in the digestive tract, with ulceration deep into the tissues-UC is limited to the colon and has less frequent complications, such as rupture of the colon, bleeding from deep ulcerations, and failure of treatment response.

In the 7MM, epidemiologists forecast that the diagnosed incident cases of UC will increase from 86,509 cases in 2015 to 95,864 cases in 2025, at an annual growth rate (AGR) of 1.08%. The US will have the highest number of diagnosed incident cases of UC over the forecast period, while Spain will have the lowest. Epidemiologists forecast that the undiagnosed prevalent cases of UC will increase from 556,966 cases in 2015 to 614,036 cases in 2025, at an AGR of 1.02%. The US will have the highest number of undiagnosed prevalent cases of UC over the forecast period, while Spain will have the lowest.

The report "EpiCast Report: Ulcerative Colitis - Epidemiology Forecast to 2025" provide an overview of the risk factors and global trends of UC in the seven major markets (7MM) (US, France, Germany, Italy, Spain, UK, and Japan). It includes a 10-year epidemiological forecast for the diagnosed incident cases, diagnosed prevalent cases, undiagnosed prevalent cases, and total prevalent cases of UC segmented by sex and age in these seven markets. The diagnosed incident cases are further segmented by stage at diagnosis and severity grading. The diagnosed prevalent cases are further segmented by severity grading. Additionally, autoimmune comorbidities, colectomy due to failure of medical management, and mortality due to complications of UC among the diagnosed prevalent cases of UC are also included in this analysis. Furthermore, the report includes diagnosed incident cases and diagnosed prevalent cases of indeterminate colitis (IC) for both sexes and all ages in the 7MM.

Table of Contents

1. Table of Contents

  • 1.1. List of Tables
  • 1.2. List of Figures

2. Epidemiology

  • 2.1. Disease Background
  • 2.2. Risk Factors and Comorbidities
  • 2.3. Global Trends
    • 2.3.1. Incidence
    • 2.3.2. Prevalence
  • 2.4. Forecast Methodology
    • 2.4.1. Sources Used
    • 2.4.2. Forecast Assumptions and Methods
    • 2.4.3. Sources Not Used
  • 2.5. Epidemiological Forecast for UC (2015-2025)
    • 2.5.1. Diagnosed Incident Cases of UC
    • 2.5.2. Diagnosed Prevalent Cases of UC
    • 2.5.3. Undiagnosed Prevalent Cases of UC
    • 2.5.4. Total Prevalent Cases of UC
    • 2.5.5. Diagnosed Incident Cases of IC
    • 2.5.6. Diagnosed Prevalent Cases of IC
  • 2.6. Discussion
    • 2.6.1. Epidemiological Forecast Insight
    • 2.6.2. Limitations of the Analysis
    • 2.6.3. Strengths of the Analysis

3. Appendix

  • 3.1. Bibliography
  • 3.2. Physicians and Specialists Included in this Study
  • 3.3. About the Authors
    • 3.3.1. Epidemiologists
    • 3.3.2. Reviewers
    • 3.3.3. Global Director of Therapy Analysis and Epidemiology
  • 3.4. About GlobalData
  • 3.5. About EpiCast
  • 3.6. Disclaimer

List of Tables

  • Table 1: Risk Factors and Comorbidities for UC and IBD
  • Table 2: Incidence of UC in the 5EU
  • Table 3: Prevalence of UC in Italy, Spain, and the UK
  • Table 4: 7MM, Sources Used to Forecast the Diagnosed Incident Cases of UC
  • Table 5: 7MM, Sources Used to Forecast the Diagnosed Prevalent Cases of UC
  • Table 6: 7MM, Sources Used to Forecast Undiagnosed Prevalent Cases of UC
  • Table 7: 7MM, Sources Used to Forecast the Total Prevalent Cases of UC
  • Table 8: 7MM, Sources Used to Forecast the Diagnosed Incident Cases of UC by Stage at Diagnosis
  • Table 9: 7MM, Sources of Epidemiological Data Used to Forecast the Diagnosed Incident/Prevalent Cases of UC by Severity
  • Table 10: 7MM, Sources of Epidemiological Data used to Forecast Mortality Due to CRC and TMC Among the Diagnosed Prevalent Cases of UC
  • Table 11: 7MM, Sources Used to Forecast Autoimmune Comorbidities Among the Diagnosed Prevalent Cases of UC
  • Table 12: 7MM, Sources Used to Forecast UC Cases Requiring Colectomy Among the Diagnosed Prevalent Cases of UC Due to Failure of Medical Management
  • Table 13: 7MM, Sources Used to Forecast the Diagnosed Incident Cases of IC
  • Table 14: 7MM, Sources Used to Forecast the Diagnosed Prevalent Cases of IC
  • Table 15: 7MM, Sources Not Used in Epidemiological Analysis of UC
  • Table 16: 7MM, Diagnosed Incident Cases of UC, Both Sexes, All Ages, N, Selected Years 2015-2025
  • Table 17: 7MM, Age-Specific Diagnosed Incident Cases of UC, Both Sexes, N (Row %), 2015
  • Table 18: 7MM, Sex-Specific Diagnosed Incident Cases of UC, All Ages, N (Row %), 2015
  • Table 19: 7MM, Diagnosed Prevalent Cases of UC, Both Sexes, All Ages, N, Selected Years, 2015-2025
  • Table 20: 7MM, Age-Specific Diagnosed Prevalent Cases of UC, Both Sexes, N (Row %), 2015
  • Table 21: 7MM, Sex-Specific Diagnosed Prevalent Cases of UC, All Ages, N (Row %), 2015
  • Table 22: 7MM, Undiagnosed Prevalent Cases of UC, Both Sexes, All Ages, N, Select Years, 2015-2025
  • Table 23: 7MM, Age-Specific Undiagnosed Prevalent Cases of UC, Both Sexes, N (Row %), 2015
  • Table 24: 7MM, Sex-Specific Undiagnosed Prevalent Cases of UC, All Ages, N (Row %), 2015
  • Table 25: 7MM, Total Prevalent Cases of UC, Both Sexes, All Ages, N, Selected Years, 2015-2025
  • Table 26: 7MM, Age-Specific Total Prevalent Cases of UC, Both Sexes, N (Row %), 2015
  • Table 27: 7MM, Sex-Specific Total Prevalent Cases of UC, All Ages, N (Row %), 2015
  • Table 28: 7MM, Diagnosed Incident Cases of IC, Both Sexes, All Ages, N, Selected Years, 2015-2025
  • Table 29: 7MM, Diagnosed Prevalent Cases of IC, Both Sexes, All Ages, N, Selected Years, 2015-2025

List of Figures

  • Figure 1: 7MM, Diagnosed Incident Cases of UC, Both Sexes, All Ages, Selected Years, 2015-2025
  • Figure 2: 7MM, Age-Specific Diagnosed Incident Cases of UC, Both Sexes, All Ages, N, 2015
  • Figure 3: 7MM, Sex-Specific Diagnosed Incident Cases of UC, All Ages, N, 2015
  • Figure 4: 7MM, Age-Standardized Diagnosed Incidence of UC (Cases per 100,000 Population), All Ages, Both Sexes, N, 2015
  • Figure 5: 7MM, Diagnosed Incident Cases of UC Segmented by Stage at Diagnosis, Both Sexes, All Ages, N, 2015
  • Figure 6: 7MM, Diagnosed Incident Cases of UC Segmented by Severity, Both Sexes, All ages, N, 2015
  • Figure 7: 7MM, Diagnosed Prevalent Cases of UC, Both Sexes, All Ages, Selected Years, 2015-2025
  • Figure 8: 7MM, Age-Specific Diagnosed Prevalent Cases of UC, Both Sexes, N, 2015
  • Figure 9: 7MM, Sex-Specific Diagnosed Prevalent Cases of UC, All Ages, N, 2015
  • Figure 10: 7MM, Age-Standardized Diagnosed Prevalence of UC, All Ages, Both Sexes, %, 2015
  • Figure 11: 7MM, Diagnosed Prevalent Cases of UC Segmented by Severity, Both Cases, All Ages, N, 2015
  • Figure 12: 7MM, Mortality Due to Complications Among the Diagnosed Prevalent Cases of UC, Both Sexes, All Ages, N, 2015
  • Figure 13: 7MM, Colectomy Due to Failure of Medical Management Among the Diagnosed Prevalent Cases of UC, Both Sexes, All Ages, N, 2015
  • Figure 14: 7MM. Comorbidities Among the Diagnosed Prevalent Cases of UC, Both Sexes, All Ages, N, 2015
  • Figure 15: 7MM, Undiagnosed Prevalent Cases of UC, Both Sexes, All Ages, Selected Years, N, 2015-2025
  • Figure 16: 7MM, Age-Specific Undiagnosed Prevalent Cases of UC, Both Sexes, N, 2015
  • Figure 17: 7MM, Sex-Specific Undiagnosed Prevalent Cases of UC, All Ages, N, 2015
  • Figure 18: 7MM, Age-Standardized Undiagnosed Prevalence of UC, All Ages, Both Sexes, %, 2015
  • Figure 19: 7MM, Total Prevalent Cases of UC, Both Sexes, All Ages, Selected Years, N, 2015-2025
  • Figure 20: 7MM, Age-Specific Total Prevalent Cases of UC, Both Sexes, N, 2015
  • Figure 21: 7MM, Sex-Specific Total Prevalent Cases of UC, All Ages, N, 2015
  • Figure 22: 7MM, Age-Standardized Total Prevalence of UC, All Ages, Both Sexes, %, 2015
  • Figure 23: 7MM, Diagnosed Incident Cases of IC, Both Sexes, All Ages, Selected Years, N, 2015-2025
  • Figure 24: 7MM, Diagnosed Prevalent Cases of IC, Both Sexes, All Ages, Selected Years, N, 2015-2025
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