市場調査レポート

iPS細胞生成に関する特許の状況

iPS Cells Generation - Patent Overview 2013

発行 France Innovation Scientifique et Transfert (FIST SA) 商品コード 203954
出版日 ページ情報 英文 152 Slides
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iPS細胞生成に関する特許の状況 iPS Cells Generation - Patent Overview 2013
出版日: 2013年04月30日 ページ情報: 英文 152 Slides
概要

当レポートでは、人工誘導多能性幹細胞(iPS細胞)分野における特許申請の状況について調査分析するとともに、1,000件以上の新規特許についてその種類別に考察してまとめ、概略下記の構成で取り上げております。

概要

  • 技術概要:幹細胞の生成とソース
  • 技術概要:再プログラミング技術
  • 世界のiPS細胞関連特許・特許出願の検索方法

特許出願動向とロケーション

  • 特許出願動向
  • 優先出願の動向とマップ
  • 特許延長マップ

特許出願者の分析

  • 主な出願者の推移
  • 最初の出願者10社が保有するポートフォリオ
  • 主な機関/産業の出願内訳
  • 出願者の共同出願
  • 出願者とその関連会社

発明者の分析

  • 主要発明者リスト
  • 主な研究チーム

ポートフォリオ分析(各項目について、出願の状況と研究機関出願者、産業出願者、投資家のポジショニングを提示)

  • 再プログラムされる細胞の複製起点
  • 再プログラムされる細胞型
  • iPS細胞生成技術
  • 再プログラミング因子1のタイプ
  • 再プログラミング因子2のタイプ
  • デリバリー方法

引用・延長・許諾

  • 最も引用された特許・特許出願のリスト
  • 最も延長された特許・特許出願のリスト
  • 機関/産業出願者の出願による許諾・却下特許:オフィス別

許諾/再審査

  • 京都大学
  • Chinese Academy of Sciences
  • 米国政府
  • Harvard university
  • Korea university
  • 細胞動力学
  • Whitehead biomedical institute
  • Advanced Industrial Science and Technology
  • California university

結論

このページに掲載されている内容は最新版と異なる場合があります。詳細はお問い合わせください。

目次

Abstract

Description/Summary

Many diseases such as cardiovascular disorders, diabetes or neurodegenerative diseases are the consequences of dysfunction of specific cells. Strategies were developed to repair or regenerate the damaged tissues using differentiated cells out of stem cells. However, ethical and scientific issues are related to the use of embryonic stem cells. In this context, induced pluripotent stem cells (iPS) appear as a promising approach. The patient's somatic cells are first dedifferentiated into iPS cells and then redifferentiated into the cell of interest. This revolutionary technology represents major scientific, societal and economic challenges and was recently rewarded by a Nobel Prize in Physiology and Medicine to Prof. Shinya Yamanaka and Prof. John Gurdon.

With over 1000 patent families qualified and analyzed out of a pool of 3000 patent families, we have analysed:

The "iPS cells generation" patent landscape

The analysis of this patent landscape shows a strong complexity of the environment and demonstrates the ability of institutional players to develop a consistent IP strategy like the one from Kyoto university. Some major players already present in 2011 increased sharply their filings: the Kyoto university, the Chinese Academy of Sciences, the laboratories of US government. New entrants have filed numerous patent applications in the last years: Korea university, AIST, Cellular Dynamics, Salk Institute and A*STAR (SG).

The "iPS cells differentiation" patent landscape

As for the thematic "iPS cells generation", the main players are mainly institutional (23 institutional applicants in the top 30) with the university of Kyoto and the laboratories of the US government at the first two places. However, industrial applicants from all over the world clearly positioned themselves on the thematic such as Cellular Dynamics (US), Cellectis (FR) or Viacyte (US). The technological breakdowns presented in this study had shown specific positioning of the players through their patent applications notably regarding the type of cell obtained from the differentiation of iPS cells. Cardiovascular, neural, pancreatic cells are the most claimed by the applicants, this corresponding to the main pathologies observed nowadays. Hepatic cells are also often claimed notably for the establishment of toxicology studies.

The "iPS cells database"

Additionally, all patents dealing with iPS cells but who were concerning neither generation nor differentiation (thus all patents related to culture, selection, isolation, etc...) were grouped together in a database to get a full overview of the iPS landscape.

These patent landscapes provide you a comprehensive panorama of the intellectual property overview and help you:

  • Identify key inventors and players involved in the generation and differentiation of iPS cells
  • Understand their positioning, the collaboration networks and their dynamics
  • Analyze their IP strategy
  • Position your company's R&D and IP portfolio
  • Discover new trends and emerging topics

Table of Contents

Overview

Generalities

  • Brief outline of the technology: generation and source of stem cells
  • Brief outline of the technology: reprogramming techniques
  • Global search strategy of patents and patent applications related to iPS cells

Evolution and location of patent filings

  • Evolution of patent filings (1999-2013)
  • Map and evolution of priority filings
  • Map of extensions

Analysis of patent applicants

  • Main applicants on the entire period (1999-2013)
  • Part of the portfolio hold by the first 10 applicants
  • Breakdown of filings of the main institutional/industrial applicants over time
  • Main co-filings between applicants
  • Applicants and their affiliates

Analysis of inventors

  • List of the main inventors
  • Main research teams

Breakdown of the patent portfolio

Breakdown of the portfolio (for each breakdown are presented the distribution of technologies, the evolution of fillings and the positioning of institutional applicants, industrial applicants and inventors)

Breakdown of the portfolio

  • 1 Origin of cell to be reprogrammed
  • 2 Type of cell to be reprogrammed
  • 3 iPS cells generation technique
  • 4 Type of reprogramming factor 1
  • 5 Type of reprogramming factor 2
  • 6 Method of delivery

Citation, extension & granted analysis

  • List of most cited patents and patent applications
  • List of the most extended patents & patent applications
  • Granted and not granted patents filed by institutional/industrial applicants by office

Applicant focuses

  • Kyoto university
  • Chinese Academy of Sciences
  • US government
  • Harvard university
  • Korea university
  • Cellular dynamics
  • Whitehead biomedical institute
  • Advanced Industrial Science and Technology
  • California university

Conclusive comments

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