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市場調査レポート

分子画像:時代の到来

Advances in Molecular Imaging: A market coming of age

発行 Espicom Business Intelligence 商品コード 208889
出版日 ページ情報 英文 292 Pages
納期: 即日から翌営業日
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分子画像:時代の到来 Advances in Molecular Imaging: A market coming of age
出版日: 2013年04月09日 ページ情報: 英文 292 Pages
概要

当レポートでは、分子画像市場の現状と動向、課題、セクター別市場予測、および市場に参入する企業の競合プロファイルなどをまとめ、概略下記の内容でお届けいたします。

エグゼクティブサマリー

イントロダクション

  • 分子画像(MI)の適用
    • 神経疾患
    • 腫瘍
    • 心血管疾患
    • ライフサイエンスおよび製薬業界での利用
  • MIモダリティ
    • ハイブリッドMRI/PETイメージング
    • ハイブリッドMRI/SPECTイメージング
    • トレーサーおよび放射性医薬品

競合展望

  • 新規市場参入企業
  • 市場統合
  • 提携開発努力
  • 市場参入障壁および小規模企業の課題

現在の市場動向

  • 核イメージングの採用
  • 市場洞察
  • PET市場における近年の発展
  • 光学画像技術の向上

市場の見通し

  • 分子画像:市場の牽引・阻害因子および将来の機会

分子画像企業

  • ABT Molecular Imaging
  • ABX
  • Advanced Accelerator Applications
  • Advanced Cyclotron Systems
  • Advanced Medical Isotope
  • Affibody
  • Agenix
  • Aleres Pharmaceuticals
  • AntiCancer
  • Aposense
  • ART Advanced Research Technologies
  • アステラス製薬
  • Avid Radiopharmaceuticals (Eli Lilly)
  • Bioscan
  • Biospace Lab
  • Bracco
  • Bruker
  • BV Cyclotron Vu
  • Cardinal Health
  • CellPoint
  • COVIDIEN (MALLINCKRODT)
  • Cyclopharma
  • Digirad
  • Dilon Diagnostics
  • Eckert & Ziegler
  • Eczacibasi-Monrol Nuclear Products
  • Erigal
  • FLUOROPHARMA MEDICAL
  • GAMMA MEDICA-IDEAS
  • GE Healthcare
  • Guerbet
  • 浜松ホトニクス
  • IBA GROUP
  • IMAGINAB
  • Imaging Diagnostic Systems
  • Immunomedics
  • INDEC Systems
  • IntraMedical Imaging
  • JAZZ PHARMACEUTICALS
  • Lantheus Medical Imaging
  • Lightools Research
  • Mediso Medical Imaging Systems
  • MiLabs
  • NAVIDEA BIOPHARMACEUTICALS
  • Naviscan
  • NEUROLOGICA (SAMSUNG ELECTRONICS)
  • NORDION
  • Novelos Therapeutics
  • NuView Life Sciences
  • OncoVision
  • PerkinElmer
  • Pharmalucence
  • Philips Healthcare
  • PIRAMAL ENTERPRISES
  • Positron
  • PROGENICS PHARMACEUTICALS
  • Proportional Technologies
  • Scintomics
  • SEDECAL
  • Seno Medical Instruments
  • 島津メディカルシステムズ
  • Siemens Healthcare
  • Sofie Biosciences
  • Spectrum Dynamics
  • Triad Isotopes
  • UltraSPECT
  • United Pharmacy Partners
  • Visualsonics (FUJIFILM SONOSITE)

付録

図表

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目次
Product Code: 978-1-909584-24-2

The market for diagnostic and molecular imaging (MI) products has had a rocky time in recent years; cost controls and the economic downturn have conspired to peg back the sector's growth. But since 2010 things have improved; pressure in the US market has eased and growth has come from increasing demand in emerging markets such as India and China. The nuclear imaging segment has not been unaffected. Ongoing supply issues of radiopharmaceuticals and negative reimbursement development have impacted SPECT to the benefit of PET.

What does the future hold for the companies and organisations that are investing US$ billions in developing molecular imaging products?

Since 2010, the market has seen stronger growth, helped by demand in under-penetrated markets, the adoption of newer-generation hybrid imaging technologies such as PET/CT and a move towards the use of PET from SPECT, necessitating the purchase of new PET systems.

The short-lived positron-emitting isotopes used in PET imaging are generally produced in a cyclotron and then synthesised on-site before patient administration. Although not requiring the use of a nuclear reactor, this limits the use of PET imaging to centres with access to a cyclotron and synthesis equipment. Therefore, a major development is the recent availability of smaller and cheaper cyclotrons which are designed to produce C-11 and F-18 isotopes economically and on-demand, without the need for radiochemistry or PET accelerator expertise.

The drive towards PET has been additionally boosted by advancement in the diagnosis of Alzheimer's disease and the approval of Avid Radiopharmaceuticals' Amyvid (florbetapir F-18 injection). Avid (owned by Eli Lilly) is the first company to achieve approval for a diagnostic PET tracer which estimates beta amyloid neuritic plaque density in adults with cognitive impairment. This is likely to become a busy marketplace with GE, Piramel and Navidea developing late-stage products whilst the focus of new research is targeting the tau proteins.

With this report you will:

  • Know the state of the molecular imaging market and recent advances in Alzheimer's diagnosis
  • Establish the future market growth with 5-year value forecasts
  • Know the clinical and regulatory challenges facing the sector
  • Assess the companies that are developing hybrid technologies
  • Review the challenges facing producers of radiopharmaceuticals and the research which is seeking alternative paths
  • Know why PET is outpacing SPECT and the advantages it brings
  • Appreciate the regulatory hurdles affecting radiopharmaceutical producers in the US
  • Understand the changing competitive landscape and market positioning of new entrants

The MI market fundamentals remain solid and there are strong opportunities for growth within the industry. These are being driven by continued innovation and new product development, beneficial demographics, an ageing installed base of imaging equipment in the developed markets of the US and Europe, and the increasing adoption of MI technologies in emerging markets.

In particular, the increasing incidence of cancer, cardiovascular and neurological diseases means that demand for faster and more accurate diagnosis, as well as drug development and pre-clinical study efforts, will continue to accelerate in coming years. In addition, MI technologies will become more widely adopted as clinical evidence is established as to their benefits, and new technological innovations continue to be brought to market, particularly related to the MI of cancer and neurological diseases such as Alzheimer's and Parkinson's.

In addition, the current lack of penetration for nuclear and molecular imaging in emerging economies is driving demand, where new facilities are being set up and lower-cost systems are in demand.

Challenges to overcome

The short and mid-term prospects for MI are to a large extent dependant on the pace of economic recovery, which will affect the ability of smaller companies to obtain financing and future healthcare budgets, particularly in Europe. In addition, uncertainties currently exist surrounding Mo-99 supply, the impact of the US medical device excise tax, new regulatory hurdles for radiopharmaceuticals in the US and whether beta amyloid PET imaging (and related technologies) will be sufficiently reimbursed to facilitate their widespread use.

A changing competitive landscape

Currently, the key players in the MI market include medical diagnostic imaging equipment manufacturers such as Philips, Siemens and GE; radiopharmaceutical and imaging agent companies such as GE, Bracco, Covidien, IBA Molecular and Lantheus Medical Imaging; and companies that operate radiopharmacies such as Cardinal Health, Triad Isotopes and Siemens. The landscape is shifting and, despite pharmaceutical companies such as BMS and Bayer leaving the MI market, others have been keen to enter.

  • Piramal Group has gained a strong position in MI. The company now owns the intellectual property and development, marketing and distribution rights for Bayer's lead compound, florbetaben, which is seen as a promised imaging agent for AD. Through the Bayer transaction, Piramal now also owns other clinical and pre-clinical agents that are in development for cardiology and oncology imaging.
  • Progenics Pharmaceuticals is focusing on developing therapeutic radiopharmaceuticals and targeted MI agents for oncology, through its acquisition of Molecular Insight Pharmaceuticals.

And it is not just Pharma companies:

  • PerkinElmer has acquired VisEn Medical and Caliper Lifesciences, who's in vivo and in vitro diagnostics are used in pre-clinical drug development work.
  • Samsung has strengthened its medical imaging business with the acquisition, in January 2013, of NeuroLogica. Although mainly focused on portable CT scanners, NeuroLogica also offers the inSPira HD portable SPECT system.

The report covers companies active in the major MI sectors

  • Nuclear Imaging
  • Near infrared or optical imaging
  • Ultrasound
  • MRI
  • MRI/PET
  • MRI/SPECT
  • Tracers and Radiopharmaceuticals

This report answers key business questions...

  • What alternatives are being considered to mitigate the ongoing supply issues with the Molybdenum-99 isotope?
  • In which therapy sectors are MI technologies playing a key diagnostic role and with what success?
  • What collaborative role are academic institutions playing in MI development?
  • Which companies are most advanced in introducing hybrid imaging systems?
  • For which tracing agent did Navidea receive FDA approval in March 2013?
  • Which 2 Spanish companies did Advanced Accelerator Applications acquire in January 2013?
  • What development in 2012 strengthened Bruker's position in the pre-clinical imaging sector?
  • What developments are helping GE maintain its leading position in the molecular imaging sector?

About the Author

This report has been researched and written by experienced and independent medical market analyst Joanne Maddox. For over 13 years she has played a pivotal role in tracking trends in medical device and equipment markets and companies. A former editor of Medical Device Companies Analysis she has also written Medical IT: Understanding the major players and products; All Change in the Advanced Wound Care Market and Point of Care Diagnostics: Players, Products and Prospects.

Table of Contents

EXECUTIVE SUMMARY

INTRODUCTION

  • Applications of MI
    • Neurological Disease
    • Oncology
    • Cardiovascular Disease
    • MI for use in LifeSciences and the Phmaceutical Industry
  • MI Modalities
    • Hybrid MRI/PET Imaging
    • Hybrid MRI/SPECT Imaging
    • Tracers and Radiopharmaceuticals

COMPETITIVE LANDSCAPE

  • New Market Entrants
  • Market Consolidation
  • Collaborative Development Efforts
  • Barriers to Market Entry and Challenges for Smaller Companies

CURRENT MARKET DYNAMICS

  • Nuclear Imaging Adoption
  • Market Insight
    • Fig.1: Diagnostic Imaging Systems Market by Modality, 2012
    • Fig.2: Medical Imaging Market, 2005-2012 (US$ billion)*
    • Fig.3: Nuclear Imaging Equipment Market, 2007-2012 (US$ billion)*
    • Fig.4: Molecular Imaging Market by End-Use Product Type, 2010
    • Molybdenum-99 Isotope Supply Issues
  • Recent Developments in the PET Market
    • Alzheimer's Disease PET Imaging
    • Lymphoseek Lymph Node Imaging
    • PET Regulatory Approval Issues
  • Improved Optical Imaging Techniques

MARKET OUTLOOK

  • Molecular Imaging: Market Drivers, Restraints & Future Opportunities
  • Fig.5: Nuclear Imaging Equipment Market, 2012-2017E (US$ million)*
  • Fig.6: Pre-Clinical Imaging Systems Market, 2012-2017E (US$ million)
  • Fig.7: Radiopharmaceuticals Market, 2012-2017E (US$ million)
  • Fig.8: Molecular Imaging End-Use Products Market, 2012-2017E (US$ million)*

MOLECULAR IMAGING COMPANIES

ABT MOLECULAR IMAGING

  • "Dose on Demand" Biomarker Generator

ABX

ADVANCED ACCELERATOR APPLICATIONS

  • Recent Events
  • Mergers and Acquisitions
  • Products
  • Research & Development: Annexin V-128
  • Current Alliances
    • UWRC SPÓ£KA Z OGRANICZONA ODPOWIEDZIALNOŚCIA, University of Warsaw
    • GE Healthcare
    • Institut Curie
    • IASON GmbH
    • European Molecular Imaging Manufacturers Association
    • Bracco
  • Financial Performance

ADVANCED CYCLOTRON SYSTEMS

  • Recent Events
  • Products
    • TR 24 Cyclotrons
    • TR 30 Cyclotrons
    • TR PET Cyclotrons
  • CycloTec R&D Programme
  • Current Alliances
    • TRIUMF
    • GE Healthcare

ADVANCED MEDICAL ISOTOPE

  • Products in Development
    • US Production of Molybdenum-99
    • Alliance with GSG International
  • Financial Performance
    • AMIC - Operating Results, 2007-2011 (US$ thousand)
    • Fig.9: AMIC - Revenue by Type, 2011
    • Latest Results

AFFIBODY

  • ABY-025 HER2-Binding Affibody Imaging Agent
    • Clinical Study Results
  • Alliance with GE Healthcare

AGENIX

  • ThromboView
    • Pulmonary Embolism Application
    • Deep Vein Thrombosis

ALSERES PHARMACEUTICALS

  • Altropane
    • Clinical Study Results
  • Navidea Biopharmaceuticals Licence Agreement

ANTICANCER

  • Current Alliances
    • UVP
    • Caliper Life Sciences (PerkinElmer)
    • INDEC Systems
    • Olympus

APOSENSE

  • [18F]-ML-10 and EarliTest
    • Clinical Trial Results
  • Current Agreements
    • IBA
    • Sigma-Aldrich

ART ADVANCED RESEARCH TECHNOLOGIES

  • ART: Recent Events
  • Products
    • Optix MX3
    • SoftScan Optical Breast Imaging System
    • Fenestra Contrast Agents

ASTELLAS PHARMA

  • Lexiscan (regadenoson)
    • Clinical Trial Results
  • Adenoscan (adenosine injection)
  • Cardiac Imaging Revenue
    • Fig.10: Astellas Pharma's Cardiac Imaging Sales, Fiscal 2008-2011 (US$ million)

AVID RADIOPHARMACEUTICALS (ELI LILLY)

  • Amyvid (florbetapir F 18 injection)
    • Clinical Study Results
  • Products in Development
    • 18F-AV-133
  • Current Alliances
    • Cardinal Health
    • PETNET Solutions (Siemens)
    • Piramal Imaging

BIOSCAN

  • Pre-Clinical Imaging Products
    • BioFLECT
    • NanoSPECT/CT and NanoPET/CT
    • HiSPECT
  • IMAPPI Consortium

BIOSPACE LAB

  • Recent Key Events
  • Products
    • Photon Imager Systems
    • Beta Imager.
  • Current Alliances
    • Centre for Advanced Biomedical Imaging at University College London
    • ImaBio Group

BRACCO

  • Products
    • CardioGen-82
  • Research and Development
    • Ultrasound MI Contrast Agents
  • Current Alliances
    • Rete Ventures
    • Nordion
    • Advanced Accelerator Applications (AAA)
    • ImaRx Therapeutics
    • VisualSonics

BRUKER

  • Recent Key Events
  • Products
    • Pre-Clinical MRI
    • Albira PET/SPECT/CT System
    • In Vivo Optical Imaging Solutions
  • Current Alliances
    • Philips
    • Aspect Imaging
    • University of York, UK
    • Iseult Programme
    • Siemens

BV CYCLOTRON VU

  • Products
  • Current Alliances
    • IBA Group
    • Alliance with VU University Medical Centre

CARDINAL HEALTH

  • Recent Key Events
  • Imaging Facilities
  • Products
    • Cardiac Imaging Agents
  • Current Alliances and Collaborations
    • Lantheus Medical Imaging
    • Eli Lilly
    • ProVision Healthcare
    • University of Washington
    • American College of Radiology Imaging Network
    • Ohio Third Frontier and Ohio State University
    • Eckert & Ziegler
    • GE Healthcare
    • Navidea Biopharmaceuticals

CELLPOINT

  • Recent Key Events
  • EC Technology
    • 99mTc-EC-G for Oncology
    • 99mTc-EC-G for Cardiology
    • 99mTc-EC-Metronidazole for Stroke and Tumour Hypoxia
  • N4 Technology
  • Dual Agent Technology
  • Beta Cell Technology
  • Current Alliances
    • Hanmi Pharmaceutical and HYUN IMC
    • MJM Productos Farmaceuticos e de Radioprotecao
    • Philips Healthcare
    • M D Anderson Cancer Center

COVIDIEN (MALLINCKRODT)

  • Recent Key Events
  • Mallinckrodt PLC
  • Products
    • Radiopharmaceuticals
  • Current Alliances
    • Rapidscan Pharma Solutions
    • Positron
    • Institute of Atomic Energy, Poland
  • Financial Performance
    • Fig.11: Covidien's Imaging Sales, 2006-2012 (US$ million)
    • Mallinckrodt in Fiscal 2012
    • Mallinckrodt plc - Revenue by Division, 2010-2012 (US$ million)
    • Fig.12: Mallinckrodt plc - Revenue by Division, 2012
    • Mallinckrodt Global Medical Imaging - Revenue by Geographic Region, 2010-2012 (US$ million)
    • Fig.13: Mallinckrodt Global Medical Imaging - Revenue by Geographic Region, 2012
    • Mallinckrodt Global Medical Imaging - Revenue by Key Product, 2010-2012 (US$ million)
    • Fig.14: Mallinckrodt Global Medical Imaging - Revenue by Key Product, 2012
    • Latest Results

CYCLOPHARMA

DIGIRAD

  • Recent Key Events
  • Products
    • ergo
    • Cardius XPO Series
  • Alliance with Dilon Diagnostics
  • Financial Performance
    • Digirad - Operating Results, 2008-2012 (US$ million)
    • Fig.15: Digirad - Revenue by Division, 2012

DILON DIAGNOSTICS

  • Recent Key Events
  • Dilon 6800 Gamma Camera
  • Dilon 6800 Acella
  • GammaLõc
  • declipseSPECT
    • Recent BSGI Clinical Trial Results
  • Current Alliances and Contracts
    • SurgicEye
    • PenRad
    • Digirad
    • Terason Ultrasound

ECKERT & ZIEGLER

  • Recent Key Events
  • Products and Services
    • Isotope Products
    • Radiopharma Products
  • Contracts and Alliances
    • Euromedic International
    • ZAG Zyklotron
    • Polish Medical University of Gdansk
    • Cardinal Health
    • Financial Performance

ECZACIBAŞI-MONROL NUCLEAR PRODUCTS

  • Mergers and Acquisitions

ERIGAL

FLUOROPHARMA MEDICAL

  • Product Pipeline
    • CardioPET
    • BFPET
    • VasoPET
    • AZPET

GAMMA MEDICA-IDEAS

  • LumaGEM Molecular Breast Imaging System
    • Clinical Study Results
  • Pre-Clinical Imaging

GE HEALTHCARE

  • Recent Key Events
  • Products
    • PET/CT +MR Imaging Platform
    • SPECT Systems
    • SPECT/CT Systems
    • Alcyone Technology Nuclear Imaging Products
    • Ventri Nuclear Cardiology System
    • PET/CT
    • PET Radiopharmacy Products
    • Nuclear and Molecular Imaging Agents
  • Research and Development
    • Research Projects
    • Research Collaborations
  • Distribution and Other Agreements
    • Advanced Accelerator Applications (AAA)
    • Rapidscan Pharma Solutions
    • Nihon Medi-Physics Joint Venture with Sumitomo Chemical
    • Lantheus Medical Imaging
  • Financial Performance
    • GE Healthcare Operating Results, 2007-2012 (US$ million)
    • Fig.16: GE Healthcare - Revenue by Product Area, 2011*

GUERBET

  • Research and Development
  • Current Alliances and Collaborations
    • Gallimed Project - Nordion and Cyceron
    • IMAkinib
    • Iseult Programme
    • Other Projects

HAMAMATSU PHOTONICS

  • Products
    • Animal PET Scanner SHR-7700
  • Research and Development
    • Reflectance Diffuse Optical Tomography

IBA GROUP

  • Recent Key Events
  • MI Products and Services
    • IBA Molecular - Radiopharmaceuticals
    • IBA RadioPharma Solutions
  • Research and Development
  • Current Alliances and Contracts
    • Piramal Imaging
    • Novation
    • KeyMarker Consortium
    • Servicio Andaluz de Salud, Spain
    • Dehnel - Particle Accelerator Components and Engineering
    • CEA, France, and IRE, Belgium
    • Bio Molecular Industries
    • Aposense
    • BV Cyclotron VU
    • Hae Dong Co Ltd
    • Lantheus Medical Imaging
    • Wilex
  • Financial Performance

IMAGINAB

  • Recent Key Events
  • Grants and Financing
  • Research Projects
  • Current Alliances and Contracts
    • Oxford Biomedica
    • H Lundbeck
    • MacroGenics
    • Singapore Radiopharmaceuticals
    • BZL Biologics
    • GE Imanet
    • KeyMarker Consortium
    • University of California, Los Angeles
    • Dainippon Seiki
    • Eurogentec
    • Singapore's Agency for Science, Technology and Research
    • GlaxoSmithKline

IMAGING DIAGNOSTIC SYSTEMS

  • CTLM System
    • FDA Approval Application
    • Fluorescence and Molecular Imaging
  • Laser Imager for Lab Animals (LILA)
  • Financial Performance
    • IDSI - Operating Results, 2008-2012 (US$)
    • Latest Results

IMMUNOMEDICS

  • LeukoScan
  • Research and Development
    • TF2 for Colorectal Cancer Imaging and Radioimmunotherapy
    • Peptides for Imaging

INDEC SYSTEMS

INTRAMEDICAL IMAGING

JAZZ PHARMACEUTICALS

  • ProstaScint
    • Clinical Study Results
  • JUBILANT DRAXIMAGE
  • Products
    • Ruby-Fill Sr-82/Rb-82 Generator and Rubidium Elution System
    • DRAXIMAGE Sestamibi
  • Research and Development
  • Current Alliances
    • Positron

LANTHEUS MEDICAL IMAGING

  • Recent Key Events
  • Products
    • TechneLite (Technetium Tc99m Generator) and LEU TechneLite
    • ABLAVAR (Gadofosveset Trisodium)
    • Cardiolite
    • Neurolite
  • DEFINITY, Neurolite and Cardiolite Supply Issues
  • Research and Development
    • Flurpiridaz F 18
    • LMI 1195 for Cardiac PET Imaging
    • BMS 753951
  • Current Alliances and Contracts
    • Institute for Radioelements, Belgium
    • FUJIFILM RI Pharma
    • Nordion
    • NTP Radioisotopes
    • Jubilant HollisterStier
    • Ben Venue Laboratories
    • Premier Purchasing Partners
    • Cardiolite and TechneLite Distribution Agreements
    • Australian Nuclear Science and Technology Organisation
    • IBA Group
  • Financial Performance
    • Lantheus Medical Imaging - Operating Results, 2007-2011 (US$ million)
    • Lantheus Medical Imaging - Sales by Key Product Line, 2008-2011 (US$ million)
    • Fig.17: Lantheus Medical Imaging - Revenue by Product Line, 2011
    • Latest Results

LIGHTOOLS RESEARCH

  • MI Products
    • Pan-A-See-Ya Panorama
    • Macro-Illumination Imaging System
    • Macro-Imaging System Plus

MEDISO MEDICAL IMAGING SYSTEMS

  • Recent Key Events
  • nanoScan Pre-Clinical Imaging
    • nanoScan SPECT/MRI
    • nanoScan PM PET/MRI
  • Clinical Imaging
    • AnyScan SPECT-CT-PET
    • Nucline Gamma Cameras
  • Current Alliances and Collaborations
    • SPADnet
    • INSERT
    • Absolute Imaging Solutions
    • Aspect Imaging

MILABS

  • Products
    • VECTor
  • Quick-Start SPECT (U-SPECTQS)
    • U-SPECT-II/CT
    • U-SPECT Scanners
  • Current Alliances
    • Mid-Atlantic Imaging Services

NAVIDEA BIOPHARMACEUTICALS

  • Recent Key Events
  • Lymphoseek
    • Clinical Study Results
  • Research and Development
    • Expanded Indications for Lymphoseek
    • RIGScan
    • NAV5001 [123I]-E-IACFT Injection (Altropane)
    • NAV4694
  • Current Alliances and Licences
    • Alseres Pharmaceuticals
    • AstraZeneca
    • Dow Chemical Company
    • Laureate Pharma
    • Cardinal Health
    • University of California, San Diego

NAVISCAN

  • Recent Key Events
  • Positron Emission Mammography Scanner
    • PEM Clinical Study Results
    • Stereo Navigator
    • MIMviewer PEM
  • Current Alliances
    • Ledford Medical Electronics
    • Chindex Medical
    • Tecnologie Avanzate
    • Nuclear Medicine Distributors
    • SCETI
    • Hae Dong Co Ltd
    • MIMVista

NEUROLOGICA (SAMSUNG ELECTRONICS)

NORDION

  • Recent Key Events
  • Products
    • Medical Isotopes
  • Current Alliances
    • The Open Joint Stock Company "Isotope" and Research Institute of Atomic Reactors, Russia
    • Lantheus Medical Imaging
    • Gallimed Project - Guerbet and Cyceron
    • Bracco
    • TRIUMF and the University of British Columbia
    • University of Ottawa Heart Institute
  • Financial Performance
    • Nordion - Results from Continuing Operations, 2010-2012 (US$ million)
    • Fig.18: Nordion - Percentage of Revenue by Segment, 2012
    • Nordion - Sales and Earning by Segment, 2010-2012 (US$ million)
    • Medical Isotope Segment Results
    • Nordion - Medical Isotope Sales by Product Line, 2010-2012 (US$ million)
    • Fig.19: Nordion - Percentage of Medical Isotope Revenue by Product Line, 2012
    • Latest Results and 2013 Outlook

NOVELOS THERAPEUTICS

  • 124I-CLR1404 (LIGHT)
  • CLR1502 (GLOW2)

NUVIEW LIFE SCIENCES

  • Alliance with Thomas Jefferson University
    • VPAC1 For Imaging Prostate Cancer
    • NLS-VPAC For Imaging Breast Cancer
    • NLS-VPAC1 Labelled with Ga-68
  • NVLS/FXA-18 For Cardiovascular Disease

ONCOVISION

  • Albira PET/SPECT/CT System
  • Mammi Breast PET Imaging System

PERKINELMER

  • Recent Key Events
  • Fluorescence Molecular Tomography Imaging Systems
    • Multispecies Imaging Module
  • Imaging Agents
    • HER2Sense
  • Caliper Life Sciences' Pre-Clinical Imaging Systems
    • IVIS Imaging Systems
    • Quantum FX MicroCT System
    • Living Image Multi Modality Software Module and the Mouse Imaging Shuttle
    • Maestro MI Systems
  • Current Alliances
    • MosaMedix
    • DuPont
    • AntiCancer
    • Merck
    • Stanford University
    • Massachusetts General Hospital

PHARMALUCENCE

  • MI Products
    • Sulfur Colloid Injection

PHILIPS HEALTHCARE

  • Recent Key Events
  • Nuclear Medicine Products
    • Ingenuity TF PET/MR
    • PET/CT
    • SPECT/CT Systems
    • BrightView SPECT
    • Nuclear Gamma Cameras
    • IntelliSpace Portal
    • Extended Brilliance Workspace
  • Pre-Clinical Imaging
    • Imalytics Workspace
  • Research and Development
    • High Tech Campus
    • Molecular Imaging R&D Projects
    • Research Alliances
  • Distribution and Licensing Agreements
    • ROSATOM
    • Bioscan
    • Sun MicroSystems
  • Financial Performance
    • Philips Healthcare: Operating Results, 2008-2012 (EUR million)
    • Fig.20: Philips Healthcare - Revenue by Segment, 2012
    • Fig.21: Philips Healthcare - Revenue by Region, 2012

PIRAMAL ENTERPRISES

  • Research and Development
    • Florbetaben PET Tracer
    • Ga68-Bombesin for Prostate Cancer PET Imaging
    • F-18-Labelled Bombesin Analogue for Imaging Prostate Cancer
    • Al18F-1 for Prostate Cancer Imaging
    • FSPG for Tumour Imaging
    • L-5-F-18-ethoxy-Tryptophan for Tumour-Specific Imaging
  • Current Alliances
    • Ion Bean Applications

POSITRON

  • Recent Key Events
  • Products and Services
    • PET Products
    • PosiRx Radiopharmaceutical System
    • Tech-Assist
  • Current Alliances and Contracts
    • Jubilant DraxImage
    • Institute of Nuclear Research, Troitsk, Russia
    • Amerinet
    • ARRONAX Cyclotron Facility, France
    • Covidien
  • Financial Performance
    • Positron - Operating Results, 2007-2011 (US$ thousand)
    • Latest Results

PROGENICS PHARMACEUTICALS

  • Recent Key Events
    • Research and Development
  • 99mTc-MIP-1404

PROPORTIONAL TECHNOLOGIES

  • Cu-62 Micro-generator
  • Products in Development
    • PET Camera for Breast Imaging
    • PET Camera for Small Animal Studies

SCINTOMICS

  • Products
    • Hotbox-III (HB-III)
    • GallElut
    • GRP Modules
    • μ-ICR
    • InViala

SEDECAL

  • SuperArgus Pre-Clinical MI Products

SENO MEDICAL INSTRUMENTS

SHIMADZU

  • MI Products
    • PET Systems
    • PET/CT Systems
    • Clairvivo Pre-Clinical PET System
  • Research Agreement with the National Cancer Center, Tokyo, Japan

SIEMENS HEALTHCARE

  • Recent Key Events
  • Molecular Imaging and PET Products
    • Biograph mMR MRI-PET System
    • PET/CT
    • SPECT and SPECT/CT Systems
    • MI Workstations and Software
    • Pre-Clinical Imaging
    • Biomarkers
  • R&D Activities
    • Siemens Molecular Imaging Biomarker Research
    • Research Agreements
  • Supply, Distribution and Licensing Agreements
    • Avid Radiopharmaceuticals (Eli Lilly)
    • Cleveland Clinic
  • Financial Performance
    • Fig.22: Siemens Healthcare: Sales by Location of Customer, 2012
    • Latest Results

SOFIE BIOSCIENCES

  • Genisys4
  • 18F-FAC Probes
  • ELIXYS

SPECTRUM DYNAMICS

  • D-SPECT Cardiac Imaging System

TRIAD ISOTOPES

ULTRASPECT

UNITED PHARMACY PARTNERS

VISUALSONICS (FUJIFILM SONOSITE)

  • Recent Key Events
  • Products
    • Vevo LAZR Photoacoustic Imaging System
    • Vevo 2100
    • Vevo 770
    • MicroMarker Contrast Agent Kits
  • Current Alliances
    • Seno Medical Instruments
    • Bracco
    • University of Virginia
    • WILEX
    • Redectane
    • Alliance with IBA Group

APPENDICES

  • APPENDIX 1 - LIST OF ABBREVIATIONS
  • APPENDIX 2 - REPORT METHODOLOGY
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