市場調査レポート
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1138308
タンパク質検出定量化の世界市場-2022-2029Global Protein Detection Quantification Market - 2022-2029 |
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タンパク質検出定量化の世界市場-2022-2029 |
出版日: 2022年10月18日
発行: DataM Intelligence
ページ情報: 英文 180 Pages
納期: 約2営業日
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世界のタンパク質検出定量化市場の成長は、外傷の数の上昇によってなどの特定の要因によって市場を駆動します。また、慢性疾患を分子レベルで理解し、治療的ソリューションを開発する必要性の高まりも、市場成長を促進する主な要因の1つです。
慢性疾患を分子レベルで理解し、治療ソリューションを開発して、これらの組織に研究開発プログラムへの資金提供を促す必要性の高まりが、予測期間中に市場を牽引すると予想されます。
米国国立がん研究所(NCI)の公衆衛生ゲノミクスは、世界中でがんの負担を減らすために、公衆衛生がん研究への個別化医療とゲノミクスを推進しています。
政府は、プロテオミクス産業の資金を調達することで、研究活動を奨励しています。このように、タンパク質の検出と定量化市場は、今後数年間で大きく成長すると予想されています。Human Proteome Organization、National Cancer Institute(NCI)、Genomic Health Inc.などの組織の存在は、プロテオミクス分野に関する研究開発や製品開発演習を支援するための資金調達を促進しています。
さらに、生物製剤の物理的・化学的分解経路のメカニズムを解明するために実施されるプロテオミクス研究は、進展を促進すると予想されます。さらに、次世代のタンパク質濃度推定技術の開発は、潜在的な可能性を持って市場を牽引すると予想されます。
その上、プロテオミクスおよびゲノミクス研究を通じて開発された様々なバイオマーカー候補は、より安全で効果的な医薬品を製造するための予測指標となり得ます。探索段階では、質量分析を用いたプロテオミクス解析により、疾患の進行に関連する特定のメカニズムに関連し、薬物治療による影響を受ける候補を認識することができます。
タンパク質の推定を簡素化する技術の進歩は続いていますが、技術やアッセイのコストが高いため、特定の状況下ではこれらのアッセイや技術の利用が制限されると予想されます。例えば、機能プロテオミクスによく使用される質量分析法(MS)は、研究者にとって高価で時間がかかると考えられています。ターゲットMSでは、ペプチドをイムノアフィニティ濃縮するために、ターゲットごとにカスタム抗体が必要です。また、ターゲットMSでは、ペプチドを免疫親和性で濃縮するため、ターゲットごとにカスタム抗体が必要となり、その分コストがかかり、時間もかかるとされています。
様々な慢性疾患を分子レベルで理解し、治療法を開発する必要性が高まっていることが、これらの組織の研究開発プログラムへの投資を支えていると推測されます。また、国立癌研究所(NCI)の公衆衛生ゲノミクスは、世界中の癌の負担を軽減するために、公衆衛生癌の研究にゲノミクスと個別化医療を取り入れることを後押ししています。
COVID-19の発生は、市場の成長にマイナスの影響を及ぼしています。センターは閉鎖され、研究所はCOVID-19検査に忙殺され、予測期間の市場成長の妨げとなるであろう。
産業分析
世界のタンパク質検出定量化市場は、ポーターの5力分析、サプライチェーン分析、規制分析、価格分析などの様々な産業要因に基づいて、市場の詳細な分析を提供します。
世界のタンパク質検出定量化市場レポートでは、約40以上の市場データ表、45以上の図、180ページの構成で提供しています。
Protein detection quantification market size was valued at US$ 2.25 billion in 2021 and is estimated to reach US$ XX million by 2029, growing at a CAGR of 9.60% during the forecast period (2022-2029).
Detection and subsequent quantification of proteins is a vital step in the understanding of post-translational modifications. It assists in understanding the functions of complex networks of peptides for use in medicine and cell biology. Increased demand for quantification of protein in laboratories that are engaged with various activities. These laboratories' activities range from drug dosing and clinical diagnostic testing to protein characterization and are likely to influence industrial growth in the years to come.
The global protein detection quantification market growth driven by certain factors such as by rising number of traumatic injuries drives the market. The market growth is also majorly driven by the increasing need to understand chronic diseases at a molecular level and develop therapeutic solutions to encourage these organizations to fund research and development programs are among the key factors driving the market growth.
Increasing need to understand chronic diseases at a molecular level and develop therapeutic solutions to encourage these organizations to fund research and development programs., is expected to drive the market during the forecast period
Public Health Genomics at the National Cancer Institute (NCI) promotes personalized medicine and genomics into public health cancer research to reduce cancer burden across the globe.
Governments are encouraging research activities by raising funds in the proteomics industry. Thus, the protein detection and quantification market are anticipated to grow significantly in the coming years. The presence of organizations such as the Human Proteome Organization, National Cancer Institute (NCI), and Genomic Health Inc. promotes funding to support R&D and product development exercises about the field of proteomics.
Furthermore, proteomic studies carried out for finding the mechanism of physical and chemical degradation pathways of biologics are anticipated to propel progress. In addition to advancements, the development of next-generation protein concentration estimation techniques is expected to drive the market with potential avenues.
Besides, various candidate biomarkers developed through proteomics and genomics research can serve as predictive indexes for producing safer and more effective drugs. In the discovery stage, differential proteomic analysis with the help of mass spectrometry enables the recognition of candidates linked with a specific mechanism relevant to disease progression and affected by drug treatment.
Although technological advancements continue to take place for simplification protein estimation, the high cost of technology and assays are anticipated to restrict the usage of these assays and technologies under certain circumstances. For instance, Mass Spectroscopy (MS), which is often used for functional proteomics, is considered expensive and slow by researchers. In targeted MS, custom antibodies are required for each target to perform immunoaffinity enrichment of peptides. This process is observed to be expensive as well as lengthy.
The increasing need to comprehend various chronic diseases at a molecular level and then develop therapeutic solutions is estimated to support these organizations in investing in research and development programs. Besides, Public Health Genomics at the National Cancer Institute (NCI) boosts the incorporation of genomics and personalized medicine into the research of public health cancer to diminish the burden of cancer all over the world.
The COVID-19 outbreak has negatively affected the growth of the market. The centers are closed, and the laboratories are busy with the COVID-19 test, which will hamper the forecast period's market growth.
Industry Analysis
The global protein detection quantification market provides in-depth analysis of the market based on various industry factors such as porter's five force analysis, supply chain analysis, regulatory analysis, pricing analysis etc.
The colorimetric assays segment is expected to grow at the fastest CAGR during the forecast period (2022-2029)
The colorimetric assays segment held the largest market share due to its convenience rate and wide availability of the reagents for its implementation. Colorimetric assays are based on the binding of a specific dye to the rhamnolipid.
Colorimetric assays help distinguish a particular enzyme from another, quantitate catalytic activity, and inhibit this activity, generate proliferative and toxicity profiles, and even determine the concentration of proteins in solution. They are a simple and convenient way to visualize biological processes.
In colorimetric assays, the substrate is converted by the enzyme into a soluble, colored reaction product. This allows precise determination of the enzyme activity by optical density, such as peroxidase activity is measured by reducing the substrate in the presence of hydrogen peroxide, producing a soluble chromogen that is measured with a spectrophotometer. These colorimetric assay methods are often used for microtiter plate-based ELISAs in combination with an automated spectrophotometer.
The testing of protein concentration was done using citrate buffer with tetra bromophenol blue, and the change of color observed was from yellow to blue. These are well-known colorimetric assays commonly used in urine analysis. The different chemicals and enzymes were spotted at the last step of the device fabrication and left to dry in the detection zones. Similar glucose and protein tests were tried on devices patterned with different methods.
Kinases and phosphatases mediate various cellular processes like metabolism, gene transcription and translation, protein-protein interactions, and apoptosis through protein phosphorylation and dephosphorylation. For this reason, many different technologies, including various colorimetric assays, exist to detect these enzymes and their activity. This factor will drive the growth of the market in the forecast period.
North America region holds the largest market share of the global protein detection quantification market
North America dominated the global protein detection quantification market and is expected to grow at the highest CAGR during the forecast period. The region is estimated to be driven by the US mainly due to leading market players in the country and a well-established healthcare framework in the US. A combination of factors such as developed infrastructure, an increase in R&D investment, and growing cases of various diseases in the region are the factors attributed to the market growth in the U.S.
The global protein detection quantification market is highly competitive with the presence of several international and local markets. Product diversification, revenue generation, and opportunities intensify Merck & Co., Inc., Danaher, RayBiotech, Inc., Innovate, Shimadzu Corporation, and PerkinElmer Inc, Bio-Rad Laboratories, Inc., Thermo Fisher Scientific, and GE Healthcare are the leading market players with significant market share. The major players are using product development, novel product launches, market expansion, and product diversification strategies for holding their position in the market.
The companies enter into collaborations, mergers, strategic partnerships, and acquisitions to expand their presence and meet the rising demand for protein detection quantification worldwide. For instance, In August 2020, Oil-Dri Corporation of America, the leading manufacturer of sorbent minerals, parent company to Amlan International, announces that the European Patent Office has issued Patent EP 2906238. The patent covers the unique formulation of two existing mineral-based natural feed additives, Varium for poultry and NeoPrime for swine, that help global animal protein producers thrive in an era of antibiotic-free production.
Bio-Rad Laboratories
Overview: Bio-Rad Laboratories, Inc. is an American company that continued to produce innovative and useful products in the healthcare industry that assist life science researchers in accelerating the discovery process, and medical diagnostic labs obtain faster better results.
Product Portfolio: DC Protein Assay Reagents Package- Reagent pack for colorimetric assays, includes 250 ml alkaline copper tartrate, 2 L dilute Folin reagent, 5 ml surfactant solution; 450 assays.
The global protein detection quantification market report would provide an access to an approx. 40+ market data table, 45+ figures and 180 pages.