Global Enzymes Market - 2019-2026
発行: DataM Intelligence
Enzymes are the catalysts made up of proteins folded into complicated shapes. These catalysts accelerate the chemical reactions that convert the one or more substances comprising the reagents, reactants, or substrates to another type of substance. The enzymes are composed of one or more long chains of interconnected amino acids. The substrate binds to the active site of an enzyme and is converted into products. The enzymes are widely used in food and animal feed, textiles and detergents, pharmaceuticals and biotechnology research and development, manufacturing industries. The enzymes market valued USD XX million in 2018 and it is expected to grow at a CAGR of XX% to reach USD XX million by 2026.
The market is driven by increasing demand for the enzymes in the food and beverage, biofuel, animal feed, and home cleaning industries. The growing application of enzymes in protein engineering technology shall stimulate market growth. Protein engineering involves the discovery and production of newer types of enzymes to catalyze reactions that do not occur naturally. The enzymes are widely used across the various applications such as food processing, pre-digestion of baby foods, germination in breweries, fruit juice clarification, cheese manufacturing, meat tenderization, and conversion of starch into glucose.
The market is witnessing the launch of the novel enzymes. For instance, in June 2020, DuPont Nutrition & Biosciences had launched the SPEZYME HN, the latest in the Spezyme line of alpha-amylase enzymes and a new inclusion in the business suite of Xcelis Ethanol Solutions. The Spezyme HN blend combines an alpha-amylase with a thermostable phytase - that means delivering industry-leading liquefaction for dry-grind ethanol plants operating under harsh conditions.
In May 2020, AB Enzymes had launched the Rohapect Mc, the next-generation classical pectinase enzyme for berries and other fruits. Rohapect Mc is suitable for berry processing and it is universally suitable for the mash and juice treatment of various fruits. The Rohapect Mc comprised of the optimal composition of carefully selected pectolytic enzyme activities. This classical pectinase enzyme provides quick and reliable pectin degradation leading to fast viscosity reduction and high juice and anthocyanin extraction as well as fast clarification and excellent juice ultrafiltration. The result is a smooth process that yields juices and juice concentrates of the highest nutritional value.
Several companies are focusing on the expansion of the enzyme production facilities. For instance, in February 2019, Hayashibara Co., Ltd., a NAGASE Group company had begun construction of a new facility to produce Pullulan and various enzymes at Okayama Plant II. Pullulan is a natural polysaccharide that is fermented by yeast from starch. Pullulan's adhesiveness, thickening, film-forming, formability, and other properties are mainly used in a wide range of applications such as food adhesives, thickeners, quality improvement, and capsule manufacture.
In November 2016, Novozymes had built a new enzyme production and supply chain facility in India to accommodate its growing business in the country. The initial investment of around 300 million Danish kroner would be spent on the site in the Patalganga industrial area near Mumbai on India's west coast. The new plant would produce enzymes using solid-state fermentation, also formulating enzymes imported from Novozymes' production sites outside India. In April 2014, Royal DSM had put its food specialties world-class enzyme facility in Yixing, Jiangsu province into the operation. The facility would serve both global and local markets, laying a foundation for the development of the DSM enzyme business in China. The facility covers an area of 4,000 square meters.
The enzymes market is segmented based on the product type as carbohydrases, proteases, lipases, polymerases & nucleases, and other enzymes. The carbohydrases segment accounts for the highest market share due to increasing usage of the carbohydrases in the textiles & leather, food & beverages, pulp & paper, and biofuel. The carbohydrases are the group of enzymes that promote the hydrolysis or synthesis of carbohydrates into sugar such as glucose and fructose. Carbohydrases are used for the production of corn syrup, ethanol, baking, and brewing. Carbohydrases are used in the beverage and pharmaceutical industries. Carbohydrases are useful for the production of prebiotic products and artificial sweeteners for the wines and juices. There are different types of carbohydrases such as amylase, cellulase, and other carbohydrases. The amylases catalyze the hydrolysis of starch into the sugars. The amylases are classified into the alpha, beta, and gamma depending on the way they attack the bonds of the starch molecules. Alpha-amylases are widespread among living organisms. Beta-amylases are present in the yeasts, molds, bacteria, and plants. The beta-amylases are used for the removal of the starchy sizing agents from textiles, and conversion of the cereal grains to the fermentable sugars. Gamma-amylases have the efficiency of cleaving certain types of glycosidic linkages in the acidic environment.
Further, the enzymes market is also classified based on the source as the plants, animals, and microorganisms. The microorganisms segment accounts for the highest market share of XX% in 2019. The enzymes sourced from the microorganisms are used in various industries such as chemical, fermentation, agricultural, pharmaceuticals, and food production. Bacterial enzymes are obtained from the Bacillus. Bacterial enzymes are widely used in food, pharmaceutical, and detergent industries. There is increasing usage of the fungi-based enzymes for the preparation and production of several products such as soy sauce, beer, baked goods, processed fruits, and dairy items. Enzymes such as amylase, protease, cellulase, lipase, and tilactase are obtained from the fungi. Some mushroom species produce enzymes such as hydrolases, esterases, and phenol oxidases.
The plants segment is expected to witness positive market growth over the forecasted period. Several enzymes such as amylase, protease, cellulase, and lipase are obtained from the plant sources. The plant-based enzymes are suitable for supporting digestive health. The fruits and vegetables are the ideal sources of the enzymes.
By region, the enzymes market is segmented into North America, South America, Europe, Asia-Pacific, Middle-East, and Africa. Among all of the regions, North America dominated the enzymes market due to the high usage of the enzymes in several industries. There is a growing development of the novel and superior performing products involving the usage of the enzymes. The high consumption of the functional foods involving the use of the enzymes for reducing the risk of the disease development shall stimulate market growth. Several enzymes such as protease, lipase, amylase, and cellulose are used in functional foods for enhancing their functional attributes such as improvement in digestion, anti-oxidation, decreased cell aging, and nutrient properties. The growing technological advancement for the increasing usage of the enzymes for the various applications shall stimulate market growth.
Asia-Pacific region is expected to have positive market growth over the forecasted period owing to the rapid industrialization. There is growing usage of the enzymes in the pharmaceuticals, food and beverages, animal feed, biofuels, pulp & paper industry, and other industries. There is increasing usage of the enzymes for the production of detergents with superior properties such as removal of stains and the ability to be used at low temperatures. The enzymes are used for the development of the animal feed products with the digestibility and enhanced nutritional value. There is growing awareness regarding the enzyme-based pharmaceuticals and protein therapies, and food and beverages.
The Enzymes market is highly competitive with the presence of several international and local market players. The product diversification, technological advancement, revenue generation, and opportunities intensify the market competition. BASF, Dupont, Associated British Foods, Novozymes, Kerry Group, Advanced Enzymes, and Aumgene Biosciences are the leading market players with significant market share.
Companies are using novel product launches, technological advancement, new product development, capacity utilization, and market expansion strategies for holding their position in the market. For instance, in May 2019, DuPont Nutrition & Biosciences had launched the industry-leading Optimase portfolio of biobased enzymes for medical instrument cleaning applications. The DuPont Optimase portfolio delivers the optimal cleaning performance in medical instrument cleaning applications, that would help the customers to optimize the formulation costs.
In February 2017, Novozyme had launched the Spirizyme T Portfolio, an advanced suite of glucoamylase enzymes with trehalase and other yield-enhancing activities that provides the most total sugar conversion in the industry. The extensive plant trials of Spirizyme T demonstrated that it reduced the amount of residual DP2 by up to 70 percent in the industry.
In December 2013, Novozymes had expanded its enzymes base in food and detergent applications.
The companies are entering into the collaborations, mergers, strategic partnerships, and acquisitions to increase the demand for enzymes and their expansion across the globe. For instance, In June 2020, Codexis, Inc. had entered into the partnership with Molecular Assemblies, Inc. to engineer enzymes to deliver differentiated and cost-effective solutions for the enzymatic synthesis of DNA. Under the terms of the agreement, Codexis would purchase $1 million in Series A preferred stock of Molecular Assemblies. The CodeEvolver platform technology would improve the DNA polymerase enzymes that are critical for enzymatic DNA synthesis. Molecular Assemblies would combine its advanced chemistries with Codexis' enzymes to drive the process to commercialization
In June 2018, Archer Daniels Midland Company had entered into the collaboration to develop, produce, and market cellulase enzymes for operators of grain-based ethanol plants. Cellulase enzymes assist in hydrolyzing the corn kernel fiber, which consists mostly of cellulose and hemicellulose carbohydrates.
In November 2017, Peaccel had entered into the collaboration with the SeSaM-Biotech for the development of the improved enzyme variants of a commercially important enzyme family. These variants would be generated with Peaccel's proprietary iSAR machine learning technology, which enables the rapid prediction and identification of improved enzyme mutants. SeSaM-Biotech would express and characterize the enzyme variants with its in-house protein expression platforms.
*The global enzymes market report will provide access to approximately 53 Market data tables, 44 figures, and 178 pages.