市場調査レポート
商品コード
1063204
酸化ストレスアッセイの世界市場(2021年~2028年)Global Oxidative Stress Assay Market - 2021-2028 |
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酸化ストレスアッセイの世界市場(2021年~2028年) |
出版日: 2022年03月03日
発行: DataM Intelligence
ページ情報: 英文 170 Pages
納期: 約2営業日
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当レポートでは、世界の酸化ストレスアッセイ市場について調査分析し、市場力学、業界分析、市場分析、競合情勢など、体系的な情報を提供しています。
Excess oxygen-derived free radicals within a cell or organism overpower the cell's or organism's innate antioxidant defences, resulting in oxidative stress. Proteins, lipids, and nucleic acids oxidize, leading to cancer, asthma, ischemia, diabetes, and cardiovascular and neurological illnesses. It is assessed using a variety of assays that aid healthcare professionals in better understanding the condition's processes and reactions.
The global oxidative stress assay market size was valued US$ XX million in 2020 and is estimated to reach US$ XX million by 2028, growing at a CAGR of XX % during the forecast period (2021-2028).
The development of a new fluorescent biosensor for measuring the redox status of metabolic methionine in cells and tissues in real-time is expected to drive market growth.
Trx1-cpYFP-fRMsr (TYfR), a genetically encoded fluorescence biosensor with exceptional specificity and sensitivity toward fMetRO (free Methionine-R-sulfoxide), allowing dynamic assessment of physiological levels of fMetRO, a novel indication of ROS and methionine redox state in vitro and in vivo. TYfR enables real-time and steady-state measurement of fMetRO from cells to whole-body level. Moreover, a thorough biochemical evaluation of the TYfR sensor demonstrated exceptional specificity and sensitivity, enabling both steady-state and real-time detection of physiological fMetRO concentrations in cells to whole-body levels. More notably, we discovered a considerable increase in fMetRO levels in human serum samples from patients with the acute coronary syndrome (ACS), one of the most serious ROS-related human diseases that becomes more apparent following the percutaneous coronary intervention utilizing the TYfR. (PCI). As a result of these findings, we believe our innovative platform has the potential to be used as a diagnostic tool for dynamic monitoring of ROS and methionine redox status, which indicates tissue damage buildup in ROS-related human illnesses. Thus, the market is expected to drive in the forecast period.
The high cost of instruments, shortage of skilled personnel for new and upcoming technologies and lack of awareness among the people are some of the factors that the market is expected to hamper the market growth.
The COVID-19 pandemic has moderately impacted healthcare systems and the market. The infection induces pathological responses, including increased inflammation, oxidative stress, and apoptosis. This situation results in impaired gas exchange, hypoxia, and other sequelae that lead to multisystem organ failure and death. Oxidative stress is a physiological state in which the cellular antioxidant buffering capability is overwhelmed by systemic quantities of reactive oxygen species (ROS), eventually causing damage to cellular macromolecules. During normal cellular metabolism, ROS and free radicals are produced. ROS plays a favorable role in crucial signaling pathways required for essential cellular processes under normal physiological settings. Moreover, the pandemic interrupted the medical supply chain, and many companies will vary to other geographic regions in the future to ensure that products remain available and protect their supply chain. However, the situation is expected to improve gradually in the forecast period.
Indirect Assays segment is expected to hold the largest market share in oxidative stress assay market
The indirect assays segment is expected to dominate in 2020. The segment benefits because of its short lifespan and fast reactivity with redox status regulatory components; it is difficult to monitor ROS levels with high accuracy and precision directly. While peroxyl radicals and hydrogen peroxide have relatively long half-lives (seconds to minutes), hydroxyl radicals are extremely reactive (half-lives of less than a millisecond). As a result, assessing oxidative stress in clinical samples via indirect detection of ROS by studying the oxidative damage these radicals cause to the cells' lipids, proteins, and nucleic acids is a viable alternative approach. Thus, the market segment is expected to hold the largest market share in the forecast period.
North America region holds the largest market share in the global oxidative stress assay market
In 2020, North America accounted for the highest revenue share. The increasing prevalence of cancer, rising geriatric population, technological advancement in the devices, well-established infrastructure and product launches, acquisition and collaborations by the market players are some factors due to which the market is expected to boost in the forecast period. For instance, cancer is a major public health problem worldwide and is the second leading cause of death in the United States. According to the American Cancer Society, In 2021, 1.9 million new cancer cases will be diagnosed, and 608,570 cancer deaths in the United States. Moreover, The risk of developing cancer increases with advancing age; 80% of all cancers in the United States are diagnosed in people 55 years of age or older. Certain behaviors and other modifiable factors also increase risk, such as smoking, having excess body weight, drinking alcohol, and having an unhealthy diet. In the US, an estimated 41 out of 100 men and 39 out of 100 women will develop cancer during their lifetime. However, these probabilities are based on cancer occurrence in the general population and may differ because of variations in individual exposures (e.g., smoking), family history, or genetic susceptibility.
Additionally, Thermo Fisher Scientific Inc. and PPD announced on April 15, 2021, that their boards of directors had authorized a formal deal under which Thermo Fisher will acquire PPD for $47.50 per share in cash, plus the assumption of roughly $3.5 billion in net debt. Thermo Fisher purchased PPD to expand into clinical research services. Thus, from the above statements, the North American region is expected to hold the largest market share in the forecast period.
Major key players in the oxidative stress assay market are Abcam, plc., Enzo Biochem, Inc., AMS Biotechnology Ltd., BioVision, Inc., Cell Biolabs, Inc., Promega Corporation, Cayman Chemical, Eagle Biosciences, Inc., Arbor Assays and Genox Corporation.
Arbor Assays specializes in developing high sensitivity assay kits, high-purity inhibitors, and antibodies for drug discovery and basic research. Products for research in non-invasive endocrinology, mitochondrial dysfunction, oxidative stress, cell signaling biomarkers, kidney damage, cholinesterase activity, and other areas are readily available. Moreover, it also offers custom assay development and testing services. We make unique kits to measure cGAMP, P450, AChE and BChE activity.
DetectX Catalase Activity: The DetectX Catalase Activity Kit is designed to quantitatively measure catalase activity in a variety of samples.
Visualize the composition of the oxidative stress assay market segmentation by product, test type, technology, disease type, end user and region highlighting the key commercial assets and players.
Identify commercial opportunities in oxidative stress assay market by analyzing trends and co-development deals.
Excel data sheet with thousands of data points of oxidative stress assay market- level 4/5 segmentation.
PDF report with the most relevant analysis cogently put together after exhaustive qualitative interviews and in-depth market study.
Product mapping in excel for the key product of all major market players
The global oxidative stress assay market report would provide an access to an approx. 45+market data table, 40+figures and 170 pages.
Service Providers/ Buyers
Industry Investors/Investment Bankers
Education & Research Institutes
Research Professionals
Emerging Companies
Manufacturers
Global Oxidative Stress Assay Market - By Product
Consumables
Instruments
Kits
Services
Global Oxidative Stress Assay Market - By Test Type
Indirect Assays
Antioxidant Capacity Assays
Enzyme-based Assays
Reactive Oxygen Species (ROS)-based Assays
Global Oxidative Stress Assay Market - By Technology
Enzyme-linked Immunosorbent Assay (ELISA)
Chromatography
Flow Cytometry
Microscopy
High-Content Screening
Label-free Detection Technology
Global Oxidative Stress Assay Market - By Disease Type
Cardiovascular Disease
Diabetes
Chronic Obstructive Pulmonary Disease (COPD)
Cancer
Asthma
Global Oxidative Stress Assay Market - By End user
Pharmaceutical and Biotechnology Companies
Clinical Laboratories
Academic Research Institutes
Contract Research Organizations
Others
Global Oxidative Stress Assay Market - By Region
North America
South America
Europe
Asia
Middle East & Africa
LIST NOT EXHAUSTIVE