プラスミドDNA製造市場：製品タイプ別、グレード別、用途別、製造タイプ別、開発段階別、地域別- 規模、シェア、展望、機会分析、2022年～2030年

細菌の細胞質内に存在し、細菌の染色体とは独立して複製される円形の二本鎖DNAをプラスミドDNAといいます。プラスミドは、染色体DNAから物理的に分離され、独立した複製が可能な細胞内の小さな余分な染色体DNA分子です。プラスミドは、バクテリアの中では小さな円形の二本鎖DNA分子として存在するのが最も一般的です。しかし、プラスミドは古細菌や真核生物にも存在することがあります。

各プラスミドは、それぞれ独自の「複製起点」を持っています。これは、宿主細菌によって確実に複製（コピー）されるDNAの伸長部です。このため、プラスミドは細菌の染色体とは無関係に自分自身をコピーすることができ、細菌細胞内にプラスミドのコピーが多数（場合によっては数百）存在することがあります。

市場力学

適切な製品とその量の要件を満たすために、既存の製造技術の革新に対する需要は、市場の主要なプレーヤーに計り知れない成長の機会を提供すると予想されます。例えば、2021年3月、ゲインズビルに拠点を置くバイオテクノロジー企業であるEvolugate, LLCは、同社の独自技術を使用してプラスミドDNA製造のスループットを改善できることを実証しています。

製品ポートフォリオを拡大するために、市場の主要企業が買収などの無機的な戦略を増やしていることは、予測期間中の市場成長を促進すると予想されます。例えば、2022年1月、アルデブロンは、細胞および遺伝子治療の分野で使用される革新的かつ独自のプラスミド構築物および製造ソリューションの開発者であるネイチャー・テクノロジー・コーポレーション（NTC）の買収を発表しました。NTCの核酸ベースの技術には、プラスミドと生物製剤の安全性と性能を向上させる独自のベクター構築物であるNanoplasmidが含まれます。

本調査の主な特徴

• 本レポートでは、世界のプラスミドDNA製造市場を詳細に分析し、2021年を基準年とした予測期間（2022-2030年）の市場規模および年平均成長率（CAGR％）を提供しています。
• 異なるセグメントにわたる潜在的な収益機会を解明し、この市場の魅力的な投資提案マトリクスを解説しています。
• また、市場促進要因、抑制要因、機会、新製品の発売または承認、市場動向、地域別の展望、主要企業が採用する競合戦略など、重要な考察を提供しています。
• 以下のパラメータに基づいて、世界のプラスミドDNA製造市場の主要企業をプロファイルします- 企業ハイライト、製品ポートフォリオ、主要ハイライト、財務実績、戦略この研究の一部としてカバーされている主要企業にはCobra Biologics and Pharmaceutical Services（Charles River Laboratories）, VGXI, Inc., Aldevron（Danaher）, Kaneka Corporation, Nature Technology, PlasmidFactory GmbH & Co. KG, Cell and Gene Therapy Catapult, LakePharma, Inc., MeiraGTx Limited, Eurofins Genomics, Vigene Biosciences, Luminous BioSciences（LBS）, LLC, GenScript, GENEWIZ, Creative Biogene, Akron Biotech, Biomay, JAFRAL Ltd., WuXi Biologics, GeneImmune Biotechnology Corp., Lonza, Greenpak Biotech Ltd., Luina Bio（AcuraBio）, Ajinomoto Bio-Pharma, Synbio Technologies, Genopis Inc., Altogen Biosystems, Puresyn, Inc., Cepham Life Sciences, Catalent, Inc., Biomiga, Waisman Biomanufacturing
• このレポートからの洞察により、企業のマーケティング担当者や経営陣は、将来の製品発売、タイプアップグレード、市場拡大、マーケティング戦術に関する情報に基づいた意思決定を行うことができるようになるはずです。
• 世界のプラスミドDNA製造市場レポートは、投資家、サプライヤー、製品メーカー、流通業者、新規参入者、財務アナリストなど、この業界のさまざまな利害関係者に対応しています。
• 利害関係者は、世界のプラスミドDNA製造市場の分析に使用される様々な戦略マトリクスを通じて、意思決定を容易にすることができます。

目次

第1章 調査目的と前提条件

• 調査目的
• 前提条件
• 略語の説明

第2章 市場の展望

• レポート内容
  • 市場の定義と範囲
• エグゼクティブサマリー
  • 市場スナップショット：製品タイプ別
  • マーケットスナップショット：グレード別
  • 市場スナップショット：アプリケーション別
  • 製造タイプ別スナップショット
  • 市場スナップショット：開発段階別
  • 市場スナップショット：地域別
• コヒーレントオポチュニティマップ（COM）

第3章 市場力学、規制、動向分析

• 市場力学
  • 促進要因
  • 抑制要因
  • 市場魅力度分析
  • 市場機会
• 製品上市
• 合併、買収、共同研究
• 規制ガイドラインとコンプライアンス
• 主な発展状況
• PEST分析
• 技術情勢
• PORTERの分析
• プライシング分析（2021年）
• プラスミドDNAワクチン開発に特化したガイドライン
• ゲノミックタイター

第4章 世界のプラスミドDNA製造市場-コロナウイルス（COVID-19）パンデミックの影響

• 経済的インパクト
• COVID-19の疫学的特徴
• 需給への影響

第5章 プラスミドDNA製造の世界市場：製品タイプ別、2017年～2030年

• ウイルスベクター
• プラスミドDNA
• 非ウイルス性

第6章 プラスミドDNA製造の世界市場（グレード別）、2017年～2030年

• GMPグレード
• R&Dグレード
• クリニカルグレード

第7章 プラスミドDNA製造の世界市場、用途別、2017年～2030年、（米国百万米ドル

• DNAワクチン
• 遺伝子治療
• 免疫療法
• RNAワクチン
• その他

第8章 プラスミドDNA製造の世界市場、製造タイプ別、2017年～2030年、（米国百万米ドル

• アウトソーシング
• 自社製造

第9章 プラスミドDNA製造の世界市場、開発段階別、2017年～2030年、（百万米ドル）

• 前臨床治療薬
• 臨床治療薬
• 上市された治療薬

第10章 プラスミドDNA製造の世界市場、地域別、2017年～2030年

• 北米
• 米国
• カナダ
• ラテンアメリカ
• ブラジル
• メキシコ
• アルゼンチン
• その他のラテンアメリカ地域
• 欧州
• 英国
• ドイツ
• イタリア
• フランス
• スペイン
• ロシア
• その他欧州
• アジア太平洋地域
• 中国
• インド
• 日本
• ASEAN
• オーストラリア
• 韓国
• その他アジア太平洋地域
• 中東地域
• GCC
• イスラエル
• その他の中東地域
• アフリカ
• 北アフリカ
• 中央アフリカ
• 南アフリカ

第11章 競合情勢

• Cobra Biologics and Pharmaceutical Services（Charles River Laboratories）.
• VGXI, Inc.
• Aldevron（Danaher）
• Kaneka Corporation
• Nature Technology
• PlasmidFactory GmbH & Co. KG
• Cell and Gene Therapy Catapult
• LakePharma, Inc.
• MeiraGTx Limited
• Eurofins Genomics
• Vigene Biosciences
• Luminous BioSciences（LBS）, LLC
• GenScript
• GENEWIZ
• Creative Biogene
• Akron Biotech
• Biomay
• JAFRAL Ltd.
• WuXi Biologics
• GeneImmune Biotechnology Corp.
• Lonza
• Greenpak Biotech Ltd.
• Luina Bio（AcuraBio）
• Ajinomoto Bio-Pharma
• Synbio Technologies
• Genopis Inc.
• Altogen Biosystems
• Puresyn, Inc.
• Cepham Life Sciences
• Catalent, Inc.
• Biomiga
• Waisman Biomanufacturing

第12章 セクション

• 調査手法
• 出版社について

Circular double-stranded DNA present in the cytoplasm of a bacteria that replicate independently from the bacterial chromosome is called a plasmid DNA. Plasmids are small extra chromosomal DNA molecules within cells that are physically separated from the chromosomal DNA and capable of independent replication. They are most commonly found as small circular double-stranded DNA molecules in bacteria. However, plasmids can be present in archaea and eukaryotes.

Each plasmid has its own "origin of replication". This is a stretch of DNA that ensures it is replicated (copied) by the host bacteria. Because of this, plasmids can copy themselves independently of the bacterial chromosome, and there can be many, possibly hundreds, copies of the plasmid within the bacterial cell.

Market Dynamics

Demand for innovation in existing manufacturing technologies, in order to meet the requirement of appropriate products and its volume is expected to provide immense growth opportunities for key players in the market. For instance, in March 2021, Evolugate, LLC, a Gainesville-based biotech company, has demonstrated that its proprietary technology can be used to improve the throughput of plasmid DNA manufacturing.

The increasing inorganic strategies such as acquisition by the key players in the market to expand product portfolio is expected to drive the market growth over the forecast period. For instance, In January 2022, Aldevron announced the acquisition of Nature Technology Corporation (NTC), a developer of innovative and proprietary plasmid constructs and manufacturing solutions that are used in the field of cell and gene therapy. NTC's nucleic acid-based technologies include Nanoplasmid, a proprietary vector construct that improves the safety and performance of plasmids and biologics.

Key features of the study:

• This report provides in-depth analysis of the global plasmid DNA manufacturing market, and provides market size (US$ Million) and compound annual growth rate (CAGR%) for the forecast period (2022-2030), considering 2021 as the base year
• It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
• This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
• It profiles key players in the global plasmid DNA manufacturing market based on the following parameters - company highlights, products portfolio, key highlights, financial performance, and strategies Key companies covered as a part of this study include Cobra Biologics and Pharmaceutical Services (Charles River Laboratories), VGXI, Inc., Aldevron (Danaher), Kaneka Corporation, Nature Technology, PlasmidFactory GmbH & Co. KG, Cell and Gene Therapy Catapult, LakePharma, Inc., MeiraGTx Limited, Eurofins Genomics, Vigene Biosciences, Luminous BioSciences (LBS), LLC, GenScript, GENEWIZ, Creative Biogene, Akron Biotech, Biomay, JAFRAL Ltd., WuXi Biologics, GeneImmune Biotechnology Corp., Lonza, Greenpak Biotech Ltd., Luina Bio (AcuraBio), Ajinomoto Bio-Pharma, Synbio Technologies, Genopis Inc., Altogen Biosystems, Puresyn, Inc., Cepham Life Sciences, Catalent, Inc., Biomiga, Waisman Biomanufacturing
• Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
• The global plasmid DNA manufacturing market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
• Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global plasmid DNA manufacturing market

Detailed Segmentation:

• Global Plasmid DNA Manufacturing Market, By Product Type:
  • Viral Vectors
    • Retroviral
    • Adenoviral
    • Lentiviral
    • Adeno Associates
    • Others
  • Plasmid DNA
    • mRNA
    • Others
  • Non-viral
    • Lipid/Polymer
    • Electroporation
    • Nanoparticles
    • Others
• Global Plasmid DNA Manufacturing Market, By Grade:
  • GMP Grade
  • R&D Grade
  • Clinical Grade
• Global Plasmid DNA Manufacturing Market By Application:
  • DNA Vaccines
  • Gene Therapy
  • Immunotherapy
  • RNA Vaccines
  • Others
• Global Plasmid DNA Manufacturing Market By Manufacturing Type:
  • Outsourcing
  • In-house Manufacturing
• Global Plasmid DNA Manufacturing Market By Development Phase:
  • Pre-Clinical Therapeutics
  • Clinical Therapeutics
  • Marketed Therapeutics
• Global Plasmid DNA Manufacturing Market, By Region:
  • North America
    • By Country:
  • U.S.
  • Canada
  • Latin America
    • By Country:
  • Brazil
  • Mexico
  • Argentina
  • Rest of Latin America
  • Europe
    • By Country:
  • Germany
  • U.K.
  • France
  • Italy
  • Spain
  • Russia
  • Rest of Europe
  • Asia Pacific
    • By Country:
  • India
  • China
  • Japan
  • Australia
  • ASEAN
  • South Korea
  • Rest of Middle East
  • Middle East
    • By Country:
  • GCC
  • Israel
  • Japan
  • Africa
    • By Country/Region:
  • South Africa
  • Central Africa
  • North Africa
• Company Profiles
  • Cobra Biologics and Pharmaceutical Services (Charles River Laboratories)*
    • Company Highlights
    • Products Portfolio
    • Key Highlights
    • Financial Performance
    • Strategies
  • VGXI, Inc.
  • Aldevron (Danaher)
  • Kaneka Corporation
  • Nature Technology
  • PlasmidFactory GmbH & Co. KG
  • Cell and Gene Therapy Catapult
  • LakePharma, Inc.
  • MeiraGTx Limited
  • Eurofins Genomics
  • Vigene Biosciences
  • Luminous BioSciences (LBS), LLC
  • GenScript
  • GENEWIZ
  • Creative Biogene
  • Akron Biotech
  • Biomay
  • JAFRAL Ltd.
  • WuXi Biologics
  • GeneImmune Biotechnology Corp.
  • Lonza
  • Greenpak Biotech Ltd.
  • Luina Bio (AcuraBio)
  • Ajinomoto Bio-Pharma,
  • Synbio Technologies, Genopis Inc.
  • Altogen Biosystems, Puresyn, Inc.
  • Cepham Life Sciences, Catalent, Inc.
  • Biomiga
  • Waisman Biomanufacturing

"*" marked represents similar segmentation in other categories in the respective section.

Table of Contents

1. Research Objectives and Assumptions

• Research Objectives
• Assumptions
• Abbreviations

2. Market Purview

• Report Description
  • Market Definition and Scope
• Executive Summary
  • Market Snapshot, By Product Type
  • Market Snapshot, By Grade
  • Market Snapshot, By Application
  • Market Snapshot, By Manufacturing Type
  • Market Snapshot, By Development Phase
  • Market Snapshot, By Region
• Coherent Opportunity Map (COM)

3. Market Dynamics, Regulations, and Trends Analysis

• Market Dynamics
  • Drivers
  • Restraints
  • Market Attractiveness Analysis
  • Market Opportunities
• Product Launches
• Merger, Acquisition, Collaborations
• Regulatory Guideline and Compliances
• Key Developments
• PEST Analysis
• Technology Landscape
• PORTER's Analysis
• Pricing Analysis (2021)
• Guidelines Specific for the Development of Plasmid DNA Vaccines
• Genomic Titer

4. Global Plasmid DNA Manufacturing Market- Impact of Coronavirus (Covid-19) Pandemic

• Economic Impact
• COVID-19 Epidemiology
• Impact on Supply and Demand

5. Global Plasmid DNA Manufacturing Market, By Product Type, 2017 - 2030, (US$ Million)

• Introduction
  • Market Share Analysis, 2022 and 2030 (%)
  • Y-o-Y Growth Analysis, 2017 - 2030
  • Segment Trends
• Viral Vectors
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2017-2030, (US$ Million)
  • Retroviral
  • Adenoviral
  • Lentiviral
  • Adeno Associates
  • Others
• Plasmid DNA
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2017-2030, (US$ Million)
  • mRNA
  • Others
• Non-viral
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2017-2030, (US$ Million)
  • Lipid/Polymer
  • Electroporation
  • Nanoparticles
  • Others

6. Global Plasmid DNA Manufacturing Market, By Grade, 2017 - 2030, (US$ Million)

• Introduction
  • Market Share Analysis, 2022 and 2030 (%)
  • Y-o-Y Growth Analysis, 2017 - 2030
  • Segment Trends
• GMP Grade
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2017-2030, (US$ Million)
• R&D Grade
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2017-2030, (US$ Million)
• Clinical Grade
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2017-2030, (US$ Million)

7. Global Plasmid DNA Manufacturing Market, By Application, 2017 - 2030, (US$ Million

• Introduction
  • Market Share Analysis, 2022 and 2030 (%)
  • Y-o-Y Growth Analysis, 2017 - 2030
  • Segments Trends
• DNA Vaccines
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2017-2030, (US$ Million)
• Gene Therapy
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2017-2030, (US$ Million)
• Immunotherapy
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2017-2030, (US$ Million)
• RNA Vaccines
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2017-2030, (US$ Million)
• Others
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2017-2030, (US$ Million)

8. Global Plasmid DNA Manufacturing Market, By Manufacturing Type, 2017 - 2030, (US$ Million

• Introduction
  • Market Share Analysis, 2022 and 2030 (%)
  • Y-o-Y Growth Analysis, 2017 - 2030
  • Segments Trends
• Outsourcing
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2017-2030, (US$ Million)
• In-house Manufacturing
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2017-2030, (US$ Million)

9. Global Plasmid DNA Manufacturing Market, By Development Phase, 2017 - 2030, (US$ Million

• Introduction
  • Market Share Analysis, 2022 and 2030 (%)
  • Y-o-Y Growth Analysis, 2017 - 2030
  • Segments Trends
• Pre-Clinical Therapeutics
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2017-2030, (US$ Million)
• Clinical Therapeutics
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2017-2030, (US$ Million)
• Marketed Therapeutics
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2017-2030, (US$ Million)

10. Global Plasmid DNA Manufacturing Market, By Region, 2017 - 2030, (US$ Million)

• Introduction
  • Market Share Analysis, By Region, 2022 and 2030 (%)
  • Y-o-Y Growth Analysis, For Regions, 2017-2030
  • Regional Trends
• North America
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, By Product Type, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Grade, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Application, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Manufacturing Type, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Development Phase, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Country, 2017 - 2030, (US$ Million)
• U.S.
• Canada
• Latin America
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, By Product Type, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Grade, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Application, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Manufacturing Type, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Development Phase, 2017 - 2030, (US$ Million
  • Market Size and Forecast, and Y-o-Y Growth, By Country, 2017 - 2030, (US$ Million)
• Brazil
• Mexico
• Argentina
• Rest of Latin America
• Europe
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, By Product Type, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Grade, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Application, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Manufacturing Type, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Development Phase, 2017 - 2030, (US$ Million
  • Market Size and Forecast, and Y-o-Y Growth, By Country, 2017 - 2030, (US$ Million)
• U.K.
• Germany
• Italy
• France
• Spain
• Russia
• Rest of Europe
• Asia Pacific
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, By Product Type, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Grade, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Application, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Manufacturing Type, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Development Phase, 2017 - 2030, (US$ Million
  • Market Size and Forecast, and Y-o-Y Growth, By Country, 2017 - 2030, (US$ Million)
• China
• India
• Japan
• ASEAN
• Australia
• South Korea
• Rest of Asia Pacific
• Middle East
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, By Product Type, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Grade, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Application, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Manufacturing Type, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Development Phase, 2017 - 2030, (US$ Million
  • Market Size and Forecast, and Y-o-Y Growth, By Country, 2017 - 2030, (US$ Million)
• GCC
• Israel
• Rest of Middle East
• Africa
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, By Product Type, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Grade, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Application, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Manufacturing Type, 2017 - 2030, (US$ Million)
  • Market Size and Forecast, and Y-o-Y Growth, By Development Phase, 2017 - 2030, (US$ Million
  • Market Size and Forecast, and Y-o-Y Growth, By Country/Region, 2017 - 2030, (US$ Million)
• North Africa
• Central Africa
• South Africa

11. Competitive Landscape

• Cobra Biologics and Pharmaceutical Services (Charles River Laboratories).*
  • Company Highlights
  • Product Portfolio
  • Key Highlights
  • Financial Performance
  • Market Strategies
• VGXI, Inc.
• Aldevron (Danaher)
• Kaneka Corporation
• Nature Technology
• PlasmidFactory GmbH & Co. KG
• Cell and Gene Therapy Catapult
• LakePharma, Inc.
• MeiraGTx Limited
• Eurofins Genomics
• Vigene Biosciences
• Luminous BioSciences (LBS), LLC
• GenScript
• GENEWIZ
• Creative Biogene
• Akron Biotech
• Biomay
• JAFRAL Ltd.
• WuXi Biologics
• GeneImmune Biotechnology Corp.
• Lonza
• Greenpak Biotech Ltd.
• Luina Bio (AcuraBio)
• Ajinomoto Bio-Pharma
• Synbio Technologies
• Genopis Inc.
• Altogen Biosystems
• Puresyn, Inc.
• Cepham Life Sciences
• Catalent, Inc.
• Biomiga
• Waisman Biomanufacturing

12. Section

• Research Methodology
• About Us