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眼疾患の概要:治療法・技術・デバイスの発展

Ocular Disorders: Rising Therapeutics, Technologies and Devices - Overview

発行 Insight Pharma Reports 商品コード 293070
出版日 ページ情報 英文 208 Pages
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眼疾患の概要:治療法・技術・デバイスの発展 Ocular Disorders: Rising Therapeutics, Technologies and Devices - Overview
出版日: 2015年06月01日 ページ情報: 英文 208 Pages
概要

当レポートでは、眼疾患について取り上げ、加齢黄斑変性症 (AMD) の概要と抗VEGF療法の詳細な調査を提供しており、主要企業のAMDに対するアプローチ、戦略、研究・製品作成において遭遇した課題などをまとめ、お届け致します。

エグゼクティブサマリー

第1章 加齢黄斑変性症 (AMD)

  • 滲出型AMD
  • 萎縮型AMD

第2章 治療効果

  • 抗VEGF療法

第3章 Oraya Therapeutics

  • 放射線治療プラットフォーム
  • 放射線量
  • 合併症の可能性・リスク因子
  • 競争上の優位性
  • 課題・改善分野
  • 今後の期待
  • Jim Taylor へのインタビュー

第4章 VisionCare Ophthalmic Technologies

  • 社歴
  • 望遠鏡技術
  • 合併症と課題
  • Reena Mishra へのインタビュー

第5章 Omeros

  • 社歴
  • PharmacoSurgeryプラットフォーム
  • 流通ルート
  • 競争上の優位性
  • 遭遇した課題
  • 検証
  • 今後の期待
  • Greg Demopulos へのインタビュー

第6章 Kala Pharmaceuticals

  • 社歴
  • 粘膜貫通製品 (MPP)
  • 競争上の優位性
  • 合併症と課題
  • 今後の取り組み
  • Kim Brazzell へのインタビュー

第7章 プラットフォームと製品

第8章 眼科産業の調査

  • 開発分野
  • 有望な目標と治療法
  • 遭遇した課題

第9章 治験・パイプラインデータ

第10章 企業プロファイル

参考資料

図表

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目次

Available to Insight Pharma Reports is Ocular Disorders: Rising Therapeutics, Technologies, and Devices Report. This report begins with outlining Age-related macular degeneration (both wet and dry) and delving into Anti-VEGF therapies in chapter 2. Further providing substantial weight to this report, several companies were interviewed on their approach to targeting wet and dry AMD, their strategies for seeking alternative therapeutic options, and the hardships they have encountered in their research and product execution.

Report highlights include:

  • Exclusive interviews from four companies (Oraya Therapeutics, VisionCare Ophthalmic Technologies, Omeros, and Kala Pharmaceuticals) providing details of their products.
  • Both invasive and noninvasive procedures are discussed, along with current treatment options and how they relate to rising therapies.
  • Demographic survey and analysis of researchers working in ocular disorders including promising therapeutic options, targets of interest, and challenges encountered.
  • Over 250 companies featuring clinical trials and pipeline data.
  • Over 200 company and institution profiles included

Table of Contents

Executive Summary

CHAPTER 1: Age-Related Macular Degeneration

  • Wet AMD
  • Dry AMD

CHAPTER 2: Therapeutic Efficacy

  • Anti-VEGF therapies
    • Pegaptanib
    • Bevacizumab
    • Ranibizumab
    • VEGF Trap-EYE

CHAPTER 3: Oraya Therapeutics

  • Radiotherapy platform
    • Automatic Positioning System (APS)
    • I-Guide
    • System software
  • Radiation dosing
  • Potential complications and risk factors
  • Competitive advantage
  • Challenges and areas of improvement
  • Future expectations
  • Interview with Jim Taylor
    • Radiation therapy
    • Competitive advantage
    • Challenges encountered
    • Areas of improvement
    • Future expectations

CHAPTER 4: VisionCare Ophthalmic Technologies

  • Company background
  • Telescope technology
  • Complications and challenges
  • Interview with Reena Mishra
    • Company background
    • Telescope technology
    • Competitive advantage
    • Complications and challenges

CHAPTER 5: Omeros

  • Company background
  • PharmacoSurgery platform
  • Pipeline
  • Competitive advantage
  • Challenges encountered
  • Validation
  • Future expectations
  • Interview with Greg Demopulos
    • Company background
    • PharmacoSurgery platform
    • OMS302
    • Competitive advantage
    • Challenges encountered
    • Validation procedure
    • Future expectations

CHAPTER 6: Kala Pharmaceuticals

  • Company background
  • Mucosal penetrating products (MPP)
  • Competitive advantage
  • Future endeavors
  • Interview with Kim Brazzell
    • Company background
    • Mucosal penetrating products (MPP)
    • Challenges encountered
    • Competitive advantage
    • Future endeavor

CHAPTER 7: Platforms and Products

CHAPTER 8: Survey of Ocular Industry

  • Areas of development
  • Promising targets and therapies
  • Challenges encountered

CHAPTER 9: Clinical Trials and Pipeline Data

CHAPTER 10

  • Company Profiles
  • 13therapeutics, Inc.
  • 2C Tech Corporation, Inc.
  • AbbVie Inc.
  • Abdi ìbrahim ìlac Sanayi ve Tic A.S. (Abdi Ibrahim)
  • AC Immune SA
  • ACADIA Pharmaceuticals
  • Aciex Therapeutics, Inc.
  • Aciont Inc.
  • Acorn Biomedical, Inc.
  • Actavis hf.
  • Acucela Inc.
  • Adamed Sp. z o.o.
  • Adenovir Pharma AB
  • AdeTherapeutics Inc.
  • Aerie Pharmaceuticals, Inc.
  • Aerpio Therapeutics, Inc.
  • Akebia Therapeutics, Inc.
  • Akorn Pharmaceuticals, Inc.
  • Alcon Laboratories, Inc.
  • Alexion Pharmaceuticals, Inc. Translational Medicine Center
  • Alimera Sciences, Inc.
  • Alkeus Pharmaceuticals, Inc.
  • Allegro Ophthalmics LLC
  • Allergan, Inc.
  • Allergan S.A.U.
  • Altacor
  • Altheos, Inc.
  • Amakem Therapeutics NV
  • AmorChem L.P.
  • AngioLab, Inc.
  • Ångstrom Pharmaceuticals, Inc.
  • Apellis Pharmaceuticals, Inc.
  • Apitope International NV
  • Applied Genetic Technologies Corp. (AGTC)
  • ArcticDx, Inc.
  • Argos Therapeutics, Inc.
  • AriBio
  • Ascendis Pharma A/S
  • AsclepiX Therapeutics, LLC
  • Asklepios BioPharmaceutical, Inc.
  • Aspireo Pharmaceuticals Limited
  • Aus Bio Limited
  • Auven Therapeutics Management L.L.L.P.
  • Avalanche Biotechnologies, Inc.
  • Avedro
  • Axxam S.p.A.
  • Bach Pharma, Inc.
  • Bausch & Lomb
  • Bausch & Lomb Canada Inc.
  • Bayer Yakuhin, Ltd.
  • BCN Peptides S.A.
  • Beijing Northland Biotech Co., Ltd.
  • Beijing Tide Pharmaceutical Co., Ltd.
  • Benitec Biopharma Ltd.
  • Betastem Therapeutics, Inc.
  • Bicycle Therapeutics Limited
  • Binex Co., Ltd.
  • Biocodex S.A.
  • Biocycive
  • BioDiem Ltd
  • Bioftalmik
  • BioMotiv LLC
  • Bionure
  • Biophytis
  • Bloomage BioTechnology Corporation Limited
  • BluBio (Yantai) Biopharmaceutical Co., Ltd.
  • Bohus BioTech AB
  • Boston Children's Hospital
  • Brill Pharma
  • Calista Therapeutics, Inc.
  • Can-Fite BioPharma Ltd.
  • Catalyst Biosciences
  • Cell Cure Neurosciences Ltd
  • CellSeed Inc.
  • Celsus Therapeutics plc
  • Celtaxsys, Inc.
  • Charlesson LLC
  • Chia Tai Tianquing Pharmaceutical Group Co., Ltd
  • China Resources Zizhu Pharmaceutical Co., Ltd
  • Circadian Technologies Limited
  • Clayton Biotechnologies, Inc.
  • Clearside Biomedical, Inc.
  • Compugen Ltd.
  • Corena Therapeutics SARL
  • D.Western Therapeutics Institute, Inc.
  • Dalian Innobioactives Co., Ltd.
  • Diaxonhit Therapeutics
  • DIOPTIC Laboratories, Inc.
  • DNAVEC Corporation
  • Dompé s.p.a.
  • Dong-A ST
  • Eleven Biotherapeutics, Inc.
  • Eli Lilly and Company
  • Emcure Pharmaceuticals Ltd.
  • Encore Vision, Inc.
  • Envisia Therapeutics™, Inc.
  • Enzo Biochem, Inc.
  • Eos Neuroscience, Inc.
  • EryDel S.p.A.
  • ESBATech, a Novartis company
  • Essex Bio-Technology Limited
  • Esteve
  • Eupraxia Pharmaceuticals Inc.
  • Europharm Laboratoires Co. Ltd.
  • Evonik Corporation
  • Exonate
  • EyeGate Pharmaceuticals, Inc.
  • EyeGene, Inc.
  • EyeTechCare SA
  • Eye Therapies LLC
  • Eyevensys SA
  • F. Hoffmann-La Roche AG
  • Farmaprojects S.A.U.
  • Farmigea S.p.A.
  • FirstString Research, Inc.
  • Foamix Pharmaceuticals Ltd.
  • Fondazione Telethon
  • ForSight Labs, LLC
  • ForSight VISION5, Inc.
  • Freedom Meditech, Inc.
  • La Fundación General de la Universidad de Valladolid FGUVa
  • Galecto Biotech AB
  • Genable Technologies Ltd.
  • Genentech, Inc.
  • Gene Signal International SA
  • GenSight Biologics
  • Genzyme® Corporation
  • GlaxoSmithKline plc
  • GrayBug® LLC
  • Griffin Discoveries BV
  • G-treeBNT Co., Ltd.
  • HanAll BioPharma Co. Ltd.
  • Hanlim Pharmaceuticals Inc.
  • Harmonic Pharma
  • Healios KK
  • Hemera Biosciences, Inc.
  • Herantis Pharma plc
  • High Point Pharmaceuticals, LLC (formerly TransTech Pharma, Inc.)
  • Horus Pharma
  • Hubei Kangzheng Pharmaceutical Co., Ltd.
  • Hyundai Pharm. Ind. Co., Ltd.
  • iCo Therapeutics Inc.
  • Iconic Therapeutics, Inc.
  • Ilsung Pharmaceuticals Co. Ltd.
  • Imagen Biotech, Inc.
  • Immco Diagnostics, Inc.
  • Immunservice GmbH
  • Implandata Ophthalmic Products GmbH
  • Imprimis Pharmaceuticals, Inc.
  • Inflamalps SA
  • InFlectis BioScience
  • InnoCore Technologies BV
  • InnoPharma, Inc.
  • Innovent Biologics, Inc.
  • Inotek Pharmaceuticals Corporation
  • InSite Vision Incorporated
  • Intellect Neurosciences, Inc.
  • InteRNA Technologies B.V.
  • International Stem Cell Corporation
  • Intrexon Corporation
  • ipal GmbH
  • Isis Pharmaceuticals, Inc.
  • iSTAR Medical SA
  • Jade Therapeutics, Inc.
  • Jiangsu Farever Pharmaceutical Co., Ltd.
  • Jiangsu T-mab BioPharma
  • Kala Pharmaceuticals, Inc.
  • KalVista Pharmaceuticals Ltd.
  • Kangmei Pharmaceutical Co., Ltd.
  • Korea Research Institute of Chemical Technology
  • Kowa Company, Ltd.
  • Kunshan RiboQuark Pharmaceutical Technology Co. Ltd.
  • Kytogenics Pharmaceuticals, Inc.
  • Laboratoires Genévrier
  • Laboratoires Théa
  • Laboratorios SALVAT S.A.
  • Laboratorios Sophia S.A. de C.V.
  • Lacerta Bio Inc.
  • LambdaVision, Inc.
  • Lee's Pharmaceutical Holdings Ltd.
  • Lexicon Pharmaceuticals, Inc.
  • Livwel Therapeutics, Inc.
  • Lotus Innovative Health, Ltd.
  • Lpath Incorporated
  • MacuCLEAR, Inc.
  • MacuLogix, Inc.
  • Mati Therapeutics, Inc.
  • Merck Serono (EMD Serono)
  • Mesoblast Limited
  • Meta-IQ
  • Mimetogen Pharmaceuticals, Inc.
  • Mitsubishi Tanabe Pharma Corporation
  • Molecular Partners AG
  • Montefarmaco OTC S.p.A.
  • Moorfields Pharmaceuticals
  • Mystic Pharmaceuticals
  • Myungmoon Pharm. Co., Ltd.
  • Nanomerics
  • Nano Retina, Inc.
  • NanoVector srl
  • NanoViricides, Inc.
  • Nektar Therapeutics
  • NEMUS Bioscience, Inc.
  • Neothetics™, Inc.
  • Neuroptis Biotech
  • Neuroscienze PharmaNess S.c.a.r.L.
  • Neurotech Pharmaceuticals, Inc.
  • Nexus Pharamaceuticals, Inc.
  • NicOx Research Institute SRL
  • NicOx S.A.
  • NightstaRx Ltd.
  • NovaBay Pharmaceuticals, Inc.
  • Novaliq GmbH
  • NovaMedica LLC
  • Novartis International AG
  • Novartis Ophthalmics AG
  • NovelMed Therapeutics, Inc.
  • Ocata Therapeutics, Inc.
  • Ocugen, Inc.
  • Oculeve
  • Oculis ehf
  • Ogenx Therapeutics Corporation, Inc.
  • Ohr Pharmaceutical Inc.
  • Omeros Corporation
  • OMIDA AG
  • ONL Therapeutics LLC
  • OphthaliX, Inc.
  • OphthalmoPharma Ltd.
  • Ophthotech Corp.
  • Opocrin S.p.A.
  • Opthea Pty Ltd
  • Ora Bio Ltd.
  • Oraya Therapeutics, Inc.
  • Otsuka Pharmaceutical Europe Ltd
  • Oxford BioMedica plc
  • OxiGENE, Inc.
  • Palobiofarma S.L
  • Panoptes Pharma GmbH
  • PanOptica, Inc.
  • Parion Sciences
  • PDL BioPharma, Inc.
  • Perrigo Company plc
  • Pfenex Inc.
  • Pfizer
  • Pharma Two B Ltd.
  • Physica Pharma
  • Pieris Pharmaceuticals, Inc.
  • Pierre Fabre SA
  • PIQUR Therapeutics AG
  • Pixium Vision SA
  • PolyActiva Pty Ltd.
  • Potentia Pharmaceuticals, Inc.
  • Present Value Ltd
  • Promedior, Inc.
  • ProRetina Therapeutics, S.L.
  • Provectus Biopharmaceuticals, Inc.
  • pSivida Corp.
  • QLT Inc
  • Quark Pharmaceuticals, Inc.
  • Rapid Pathogen Screening, Inc.
  • Reata Pharmaceuticals, Inc.
  • Regeneron Pharmaceuticals
  • RegeneRx Biopharmaceuticals, Inc.
  • REGENXBIO Inc.
  • ReNeuron Group plc
  • Resolvyx Pharmaceuticals, Inc.
  • RestorGenex Corporation
  • RetroSense Therapeutics LLC
  • Rigel Pharmaceuticals, Inc.
  • River Vision Development Corp.
  • Roche Diagnostics GmbH
  • Roche SAS
  • R-Tech Ueno, Ltd.
  • RXi Pharmaceuticals Corporation
  • Sam Chun Dang Pharm. Co., Ltd
  • Samil Pharm. Co., Ltd.
  • SanBio, Inc.
  • Sanitas AB
  • Sanofi S.A.
  • Santen Pharmaceutical Co., Ltd.
  • Santhera Pharmaceuticals
  • SATT Lutech
  • SCYNEXIS, Inc.
  • Senju Pharmaceutical Co., Ltd
  • Shire plc
  • SIFI SpA
  • Silvanols
  • Sirnaomics, Inc.
  • SK Biopharmaceuticals
  • Solx, Inc.
  • Spark Therapeutics, Inc.
  • Specialised Therapeutics Australia Pty Ltd
  • Starpharma
  • Stealth Peptides International (Shanghai) Inc.
  • Stelic Institute & Co., Inc.
  • Stelis Biopharma Pvt. Ltd.
  • StemCells, Inc.
  • Strathclyde University, Health Technologies
  • Streuli Pharma AG
  • Strides Arcolab Ltd.
  • Sucampo Pharmaceuticals, Inc.
  • Sun Pharma Advanced Research Company (SPARC) Ltd.
  • Suzhou Sirnaomics Biopharmaceuticals Co. Ltd.
  • Sylentis S.A.
  • SynCore Biotechnology Co., Ltd
  • Synovo GmbH
  • Tacere Therapeutics, Inc.
  • Tactical Therapeutics, Inc.
  • Taejoon Pharm Co., Ltd.
  • Taiwan Liposome Company Ltd.
  • TearScience®, Inc.
  • Teijin Pharma Limited
  • ThromboGenics NV
  • TLC Biopharmaceuticals B.V.
  • TOA EIYO LTD.
  • TopiVert Ltd.
  • TRACON Pharmaceuticals, Inc.
  • TRB Chemedica International S.A.
  • TxCell
  • UNIMED PHARMA, spol. s r.o.
  • UNITHER Pharmaceuticals
  • University of Nottingham
  • University of Santiago de Compostela
  • Valeant Pharmaceuticals International, Inc.
  • Valentia Biopharma S.L.
  • Venture Life Ltd
  • Vibalogics GmbH
  • VisionCare Ophthalmic Technologies. Inc.
  • VISIOTACT Pharma
  • Wellstat Ophthalmics Corporation
  • X-BODY Biosciences, Inc.
  • Xcovery Vision
  • Xediton Pharmaceuticals Inc.
  • XOMA Corporation
  • Youcare Pharmaceutical Group Co., Ltd.
  • ZeaVision®, LLC
  • Ziarco

References

TABLES

  • Table 2.1: Clinical status for common therapies for wet AMD
  • Table 3.1 Platform specifications
  • Table 4.1: Platform specifications
  • Table 5.1: Targets and their clinical status
  • Figure 6.1: Targets and their clinical status
  • Table 7.1: Targets in clinical stages
  • Table 7.2: Therapeutic platform specifications

FIGURES

  • Figure 8.1: Areas of research
  • Figure 8.2: Ocular disorders of interest
  • Figure 8.3: Promising therapies for ocular diseases
  • Figure 8.4: Promising targets for ocular therapies
  • Figure 8.5: Challenges encountered
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