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The Global Outlook for Next Generation Sequencing: Usage, Preferences, & Budgets

発行 BioInformatics, LLC 商品コード 219120
出版日 ページ情報 英文
納期: 即日から翌営業日
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世界の次世代シーケンシング見通し:使用・好み・予算 The Global Outlook for Next Generation Sequencing: Usage, Preferences, & Budgets
出版日: 2011年10月19日 ページ情報: 英文






  • 自発的な認識:次世代シーケンシングプロバイダーとプラットフォーム
  • 補助的認識/使用検討:次世代シーケンシングプロバイダーとプラットフォーム
  • カテゴリー別"ベストインクラス"
  • 所有する次世代シーケンシング装置、使用されている装置
  • 今後2年以内に購入する次世代シーケンシング装置


  • 装置別満足度
    • 実験ごとに必要なDNA/RNAの量
    • 応用への適切性
    • 自動化能力
    • 入手可能なソフトウェア分析ツール
    • ベース別コスト
    • 使いやすさ
    • 信頼性
    • サイズ
    • リード数
    • 準備時間
    • 処置時間
    • リード長さ
    • 生産性・精度
    • シーケンシングデータの品質
    • データファイルのサイズ
    • 装置コスト
    • 歩留まり
  • 装置プラットフォーム別全体的満足度
  • サプライヤー別満足度
    • ブランド名・企業の評判
    • ピアレビュー文献への引用
    • カスタマーサービス
    • カスタマートレーニング(装置の使用)
    • 財務
    • 技術革新レベル
    • メンテナンス/サービス保証
    • プロモーション/値引き
    • 営業担当者
    • 技術的サポート
  • サプライヤー別全体的満足度
  • サプライヤー別価値格付け
  • 大手サプライヤーによる推奨
  • シーケンシングプラットフォームにおける類似性と差異


  • 次世代シーケンシング研究の"青写真"
  • 次世代シーケンシングプラットフォームの主な応用
  • 次世代シーケンシングワークフローの場所(現状/計画)
  • 次世代シーケンシングワークフロー
    • 所要時間、ステップごとの難度
    • 課題
    • サプライヤーの対応
    • 必要な最大リード長さ
    • 必要な最大歩留まり


  • 回答者の購入における役割
  • 資金源
  • 次世代シーケンシング装置に用いる資金の割合
  • 新規に次世代シーケンシング装置を購入する際の最重要プラットフォーム特性
  • 新規に次世代シーケンシング装置購入の際の最重要プロバイダー特性/サービス


  • 2010年度、2011年度、2012年度の予算総額
  • 次世代シーケンシングに費やす予算比率
  • 次世代シーケンシング予算


  • サンプルマネジメント
  • 使用する/使用予定のキット、消耗品
  • キット・消耗品への満足度
  • ブランドの好み
  • 次世代シーケンシングに用いられる関連技術


  • 現在の制限因子
  • 次世代シーケンシングワークフローへの"最重要な改善点"
  • "最重要な改善点"の程度(定性的)


  • 次世代シーケンシング製品に関する情報源
  • 回答者の指名
  • 回答者のラボ/グループで働く研究者


Product Code: 11-003

Gene sequencing technology, initially semi-automated in the 1980' s, is rapidly advancing to support cutting-edge exploration into disease diagnostics and therapeutic intervention. With the ability to sequence millions of DNA segments in a single run and identify diagnostic markers for multiple species in a sample - without cloning or PCR amplification - sequencing technologies are on the cusp of a new generation. Coined “third gen,” the race for genomics tool suppliers to develop faster more cost-effective sequencing instruments is fueled by a global mission to reduce the cost of sequencing the human genome to under $1,000 US dollars. Cheaper and faster are the keywords in sequencing innovation. But new technologies don' t necessarily render old ones obsolete, as the early sequencing techniques (e.g., Sanger) still present the best solution for specific applications.

Balancing innovation with the realities of how quickly labs will adopt new platforms is the challenge for next generation sequencing (NGS) product suppliers. New technologies create excitement, but installing and learning how to incorporate new systems into ongoing research requires a desire (and commitment) from the lab. BioInformatics LLC' s upcoming report, The Global Outlook for Next Generation Sequencing: Usage, Preferences and Budgets, was designed to help NGS product suppliers move forward into uncharted territory in a strategic way so as to optimize solutions that are relevant to the research and realistic for laboratories to adopt.

This worldwide study of the academic and pharma/biotech sectors provides a market analysis of NGS and an assessment of the brand equity and brand positioning of companies providing NGS instrumentation and consumables. To better understand the current market for NGS technologies, the report includes an in-depth exploration of NGS technologies currently deployed, workflow and types of applications. To assist with competitive benchmarking, study respondents are asked to compare brands across multiple criteria (e.g. accuracy of reads, ease of use, innovation of technology, turnaround time/experiment time etc.) and rank them on value for price paid, satisfaction and gaps in product offerings. Understanding current usage and brand preferences help to identify must-have features and unmet needs, which illuminates gaps in individual vendor offerings and opportunities in the market as a whole.

For future planning purposes, the report includes average lab budgets for NGS and predicted growth in lab budgets through 2012. Purchasing drivers are delineated, and upcoming plans, criteria and funding for purchases are explored. In addition, the report provides direction from the scientists as to where the market is headed and the impact of new markets such as diagnostics and personal genomics.

The Global Outlook for Next Generation Sequencing: Usage, Preferences and Budgets was designed for next generation sequencing product suppliers who are navigating a technology frontier that has captured the imagination of researchers, healthcare providers and entrepreneurs. This report will help suppliers allocate resources to new applications & markets and to optimize current products by making them more responsive to scientists who are already engaged in the next generation of whole genome sequencing.


This study will explore market analytics:

  • Adoption projections for users of NGS technology
  • Technology drivers
  • Market share by brand of NGS platform
  • Sources of funding
  • Percent of annual budgets spent on NGS
  • Primary research application(s)
  • Unmet current and future NGS technology needs
  • ...and more!

This study will also explore brand analytics:

  • Brand awareness of NGS instrument brands
  • Brand comparisons
  • Purchasing drivers
  • Satisfaction levels with NGS platform attributes
  • Willingness to recommend
  • Most popular NGS provider
  • ...and more!


About the Respondents

  • Type of lab
  • Use of next generation sequencing
  • Motivations for using next generation sequencing

Awareness and Use

  • Unaided, top-of-mind awareness: next generation sequencing providers and platforms
  • Aided awareness/consideration of use: next generation sequencing providers and platforms
  • “Best in class” by category:
    • Accuracy of reads
    • Assay cost
    • Cost of platform
    • Ease of use
    • Innovation of sequencing technology
    • Turnaround time/Experiment time
  • Next generation sequencing instruments owned, instruments used, and primary instrument used
  • Next generation sequencing instrument purchases planned within the next 2 years

Customer Satisfaction

  • Satisfaction by instrument:
    • Amount of DNA/RNA needed per experiment
    • Appropriate for my application
    • Automation capabilities
    • Available software analysis tools
    • Cost per base
    • Ease of use
    • Instrument reliability
    • Instrument size
    • Number of reads
    • Preparation time (prep and pre-amp)
    • Procedural time (total time)
    • Read length
    • Reproducibility/accuracy
    • Sample preparation requirements
    • Sequencing data quality
    • Size of data files produced
    • Instrument cost
    • Yield
  • Overall satisfaction by top instrument platforms
  • Satisfaction by supplier:
    • Brand name/company reputation
    • Citations in peer-reviewed publications
    • Customer service
    • Customer training (in use of the instrument)
    • Financing
    • Level of technological innovation
    • Maintenance/service warranty
    • Promotions/discounts
    • Sales reps
    • Technical support
  • Overall satisfaction by supplier
  • Value rating by supplier
  • Likelihood of recommendation by top suppliers
  • Perceived similarities and differences in sequencing platforms with respect to:
    • Innovation
    • Accuracy of reads
    • Ease of use
    • Turn around time/experiment time

Use and Applications of Next Generation Sequencing

  • “Big picture” focus of next generation sequencing research
  • Primary application for next generation sequencing platforms
  • Location (current/planned) of next generation sequencing workflow
  • Next generation sequencing workflow:
    • Time spent, level of difficulty by step
    • Bottlenecks
    • How suppliers can address bottlenecks (qualitative)
    • Maximum read length typically needed
    • Maximum yield typically needed

Purchasing a Next Generation Sequencing Platform

  • Respondents' role in purchasing
  • Sources of funding
  • Percent of funding used for next generation sequencing instrumentation
  • Most important platform features when purchasing a new next generation sequencing instrument
  • Most important provider attributes/services when purchasing a new next generation sequencing instrument

Lab Budgets for Next Generation Sequencing

  • Total budget for FY2010, FY2011, FY2012
  • Percent of total budget spent on next generation sequencing
  • Next generation sequencing budget spending

Consumables and Techniques Supporting Next Generation Sequencing

  • Sample management
  • Sample prep
  • Sample selection
  • Pre-sequencing amplification
  • Kits and consumables used/planned to use
  • Satisfaction with kits and consumables (qualitative)
  • Brand preferences: kits and consumables
  • Brand preferences explained (qualitative)
  • Techniques used in conjunction with next generation sequencing (PCR, Sequence Capture, Gel/Blotting, Misc.)

Future of Next Generation Sequencing

  • Currently limiting aspects of next generation sequencing
  • “Most significant improvement” to next generation sequencing workflow
  • Degree of “most significant improvement” (qualitative)

Learning About Next Generation Sequencing Technology and New Products

  • Sources of information for next generation sequencing product offerings
  • Respondent nominations for:
    • Best Next Generation Sequencing Conference
    • Best Scientific Journal
    • Best Reference Website
    • Best Research Center of Excellence
    • Best Thought or Knowledge Leader in the Field
  • Total researchers working in respondent labs/groups


  • If cost were no object, would you get your own genome sequenced? Why or why not?


Most Significant Improvement to Your
Next Generation Sequencing Workflow

©2011 BioInformatics, LLC

Most Informative Sources of Next Generation
Sequencing Product Information

©2011 BioInformatics, LLC


Sources of Independent, Unbiased Research

Unlike reports from other firms that are based on an analyst' s subjective summary of information from publicly available sources, our reports are based on the results of detailed surveys of hundreds - even thousands - of scientific and medical professionals who buy your products.

Developed by a Team of Experts

Our questionnaires are developed by a multi-disciplinary team of scientists, industry veterans and market research experts with years of experience. These professionals understand that survey questions need to be asked in a way that ensures the answers will directly address the business challenges you face. Once the survey data is collected, this same team creates a unique report that presents the reader with a thorough understanding of the topic and the scientific and business implications of the results based on sophisticated statistical analytics.

Custom Analysis & Research Available

If you' d like to delve deeper into the data from a study, we can always perform custom cross-tabulations or other analysis on your behalf. We can even pose follow-up questions to respondents who answered in a particular way or conduct a custom study to extend your knowledge.

Carefully Selected Survey Participants

When others promote results from their online surveys, they fail to mention the uncontrolled nature of their broadcast email invitations. To provide you with the most valid and accurate results possible, the respondents to our surveys are members of our unique online panel - The Science Advisory Board® - which consists of more than 66,000 verified life science and biomedical professionals who have agreed to take part in our surveys, focus groups and other market research activities. These respondents are carefully selected based on their professional qualifications, market segments and geographic regions - we can even select them based on the products they use and their preferred suppliers.

Table of Contents

Section 1: Presentation of Key Findings

  • Introduction
  • The Evolution of Next Generation Technology
  • Factors Affecting Next Generation Sequencing Platform Sales
  • Next Generation Technology Market Outlook
  • Next Generation Sequencing Workflow Analysis
  • Next Generation Sequencing Provider Profiles
  • Illumina/Solexa Sequencing
  • Life Technologies: SOLiD Sequencing and Ion Torrent
  • Roche/454 Sequencing
  • Demographics of Study Participants

Section 2: Methodology and Questionnaire

  • Questionnaire Overview
  • Questionnaire Design
  • Analytical Techniques
  • Demographics
  • Questionnaire

Section 3: Appendices

  • Appendix A: Insights and Perspectives
  • Appendix B: Other Publications
  • Appendix C: About BioInformatics LLC
  • Appendix D: Our Valued Clients
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