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構造生物学の探求:膜タンパク質構造研究に用いられるツールと技術

Exploring Structural Biology: Tools & Techniques Used in the Study of Membrane Protein Structure

発行 BioInformatics, LLC 商品コード 143185
出版日 ページ情報 英文 181 Pages
納期: 即日から翌営業日
価格
こちらの商品の販売は終了いたしました。
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構造生物学の探求:膜タンパク質構造研究に用いられるツールと技術 Exploring Structural Biology: Tools & Techniques Used in the Study of Membrane Protein Structure
出版日: 2010年11月17日 ページ情報: 英文 181 Pages

当商品の販売は、2016年07月01日を持ちまして終了しました。

概要

当レポートでは、膜タンパク質構造生物学研究に用いられるツール市場について詳細に分析し、研究のワークフローとツール、意思決定要因、製品カテゴリー別サプライヤーシェアなどをまとめ、概略下記の構成でお届けいたします。

科学者の構造生物学研究

  • 地域
  • 学術機関、政府、産業界
  • 研究分野
  • 研究予算

研究アプローチと技術

  • 膜構造生物学ワークフロー

コンピュータ分析

  • コンピュータ分析の実施理由
  • コンピュータ分析に用いられるIn Silicoツール
  • In Silicoツールの使用上の変化
  • コンピュータツール選定因子
  • コンピューティングプラットフォーム
  • 2010年度のコンピュータプロテオミクスツール支出
  • 2011年度のコンピュータプロテオミクスツール予算

膜タンパク質抽出

  • 評価の高いサプライヤー
  • 評価されている膜タンパク質抽出キット
  • 社内抽出方法
  • 近年の改良
  • 2010年度の支出実績
  • 2011年度の予算 他

内在性膜タンパク分析

  • 評価される電気泳動タンパク質分析技術
  • サプライヤー:一次元ゲル電気泳動装置および試薬
  • サプライヤー:二次元ゲル電気泳動装置および試薬
  • 2010年度の支出実績
  • 2011年度の予算 他

HPLC

  • 膜タンパク質構造生物学研究におけるHPLCワークフロー
  • サプライヤー:膜タンパク質構造生物学のためのHPLC装置
  • 評価されるサプライヤー
  • 最近HPLC装置を購入した時期
  • 次の購入予定時期
  • 2010年度の支出実績
  • 2011年度の予算

質量分析

  • ワークフロー
  • 実施理由
  • 用いられる技術
  • 評価されるサプライヤー
  • イオン化ソース
  • 質量分析装置
  • 細分化技術 他

核磁気共鳴分光学(NMR)

  • ワークフロー
  • 実施理由
  • 評価されるサプライヤー
  • メーカー選定のための重要因子
  • 最近NMR装置を購入した時期
  • 次の購入予定時期
  • 2010年度の支出実績
  • 2011年度の予算

その他の分析

目次
Product Code: 10-004

While the study of membrane proteins is not a new field, technological limitations and challenges have plagued researchers for decades. Recent technological advancements and the introduction of computational approaches to the analysis of membrane components have brought new life to membrane structural biology, creating opportunities for suppliers of membrane structural biology products.

Unique and innovative methods are being developed for membrane protein extraction, characterization, and structure determination of biologically significant membrane proteins, opening doors in the membrane structural biology market. Scientists are applying techniques such as in silico computational analysis, isoelectric focusing, one and two-dimensional gel electrophoresis, high-performance liquid chromatography (HPLC), nuclear magnetic resonance (NMR), and mass spectrometry (MS) to better understand the structure and functional interactions of cellular membrane proteins, leading to the design of more effective therapeutics for many human diseases. The growing number of platforms, products and tools offered by niche membrane biology companies, and major life science companies are drawing in more and more researchers previously restricted to studying soluble proteins.

BioInformatics LLC introduces Exploring Structural Biology: Tools and Techniques Used in the Study of Membrane Protein Structure to provide a roadmap for suppliers who seek to explore new market opportunities. This report identifies technologies and areas with the highest potential for rapid growth in the membrane structural biology market, i.e., research focuses, approaches and techniques, in silico computational tools used, protein extraction methods, integral protein analysis methods, and HPLC, NMR and MS platforms. In addition, Exploring Structural Biology: Tools and Techniques Used in the Study of Membrane Protein Structure focuses on anticipated technology platform and product purchasing trends to assist suppliers with long-term strategies that will yield a viable market position. Detailed market share information and projections are provided by technology type, along with membrane structural biology research budget data and expected changes through 2011. Suppliers will be able to use this report to anticipate areas of product growth and saturation.

Exploring Structural Biology: Tools and Techniques Used in the Study of Membrane Protein Structure was designed to provide membrane structural biology product suppliers with critical insights as to customer goals and perceptions of membrane protein structure advances. Scientific publications and conferences targeting membrane structure researchers are noted, enabling suppliers to maximize the marketing message. Customer experience, product usage changes and most important product features are also presented, allowing companies to gain an understanding of which membrane structural biology products, technologies and methods are expected to continue to grow.

OBJECTIVES

The primary objective of this report is to provide life science product suppliers with insight into the market for tools used in membrane protein structural biology research:

  • Estimate average laboratory spending on membrane protein structural biology research and growth by individual product categories
  • Understand the workflow and tools used in membrane protein structural biology research including such methods as HPLC, mass spectrometry, NMR, computational methods, and electrophoresis based methods
  • Identify key decision drivers in choosing suppliers for tools used in membrane protein structural biology research
  • Asses supplier share by usage for different product categories
  • Key areas of research interest related to membrane structural biology

KEY FINDING

For which reasons do you perform MS analysis on membrane proteins?

REPORT HIGHLIGHTS

Scientists' Structural Biology Research

  • Region
  • Academic, government, industry
  • Scientific discipline
  • Research budget

Research Approaches and Techniques

  • Membrane structural biology workflows
  • Analysis and/or quantification of integral membrane proteins
  • Computational analysis of integral membrane protein sequences
  • Extraction of integral membrane proteins from complex samples

Computational Analysis

  • Reasons to perform computational analysis
  • In silico tools used for computational analysis
  • Change in use of in silico tools
  • Explanation of changes in use of in silico tools
  • Factors in selecting computational tools
  • Computing platforms
  • Lab expenditures on computational proteomics tools in FY2010
  • Expected lab expenditures on computational proteomics tools in FY2011

Membrane Protein Extraction

  • Popular suppliers
  • Popular membrane protein extraction kits
  • In-house extraction methods
  • Recent modifications in extraction methods
  • Explanation of modifications
  • Most important factors in selection of methods for membrane
  • Lab expenditures on membrane protein extraction tools in
  • Expected lab expenditures on membrane protein extraction

Analyzing Integral Membrane Proteins

  • Popular electrophoresis-based protein analysis techniques
  • Popular suppliers: One-dimensional gel electrophoresis equipment and reagents
  • Popular suppliers: Two-Dimensional gel electrophoresis equipment and reagents
  • Pre-cast gels in membrane structural biology research
  • Popular suppliers: Pre-cast gels for membrane structural biology research
  • Recent changes in purchasing habits: Electrophoresis gels
    • Reasons for changes in purchasing habits: Electrophoresis gels
  • Factors in selecting a source for pre-cast electrophoresis gels
  • Lab expenditures on pre-cast gels
  • Lab expenditures on electrophoresis equipment and reagents in FY2010
  • Expected lab expenditures on electrophoresis equipment and reagents in FY2011

HPLC

  • HPLC workflow in membrane structural biology research
  • Suppliers: HPLC instruments for membrane structural biology research
  • Important factors in selecting a manufacturer for HPLC instruments
  • Popular suppliers
  • Time since most recent HPLC instrument purchase
  • Estimated time frame for next-planned HPLC instrument purchase
    • Estimated budget for next-planned HPLC instrument purchase
  • Lab expenditures on HPLC equipment and reagents in FY2010
  • Expected lab expenditures on HPLC equipment and reagents in FY2011

Mass Spectrometry (MS)

  • Nature of workflow with MS
  • Reasons to perform MS analysis on membrane proteins
  • Techniques used for MS analysis of membrane proteins
  • Popular suppliers
  • Ionization sources for MS analysis of membrane proteins
  • Mass analyzers used in MS analysis of membrane proteins
  • Fragmentation techniques used in tandem MS analysis of membrane proteins
  • Important factors in selecting a manufacturer of MS instruments
  • Recent changes in goals of MS analysis of membrane proteins
  • Time since most recent MS instrument purchase
  • Estimated time frame for next-planned MS instrument purchase
    • Estimated budget for next-planned MS instrument purchase
  • Lab expenditures on MS equipment and reagents in FY2010
  • Expected lab expenditures on MS equipment and reagents in FY2011
  • Technological advancements: MS in the last 5 years (membrane structural biology)

Nuclear Magnetic Resonance Spectroscopy (NMR)

  • Nature of NMR workflow
  • Reasons to perform NMR in analysis of membrane proteins
  • Popular suppliers
  • Important factors in selecting a manufacturer for NMR instruments
  • Time since most recent NMR instrument purchase
  • Estimated time frame for next-planned NMR instrument purchase
    • Estimated budget for next-planned NMR instrument purchase
  • Lab expenditures on NMR equipment and reagents in FY2010
  • Expected lab expenditures on NMR equipment and reagents in FY2011
  • Technological advancements: NMR in the last 5 years (membrane structural biology)

Additional Analysis

  • Years researching membrane structural biology
  • Primary research interests in membrane structural biology
  • How suppliers can add value to membrane structural biology workflow
  • Regularly-read publications
  • Conferences

KEY FINDING

What THREE factors are the most important to you when selecting a method for membrane protein extraction?

WHY CHOOSE OUR REPORTS?

Sources of Independent, Unbiased Research

Unlike reports from other firms that are based on an analyst's subjective summary of information from publicly available sources, our reports are based on the results of detailed surveys of hundreds even thousands of scientific and medical professionals who buy your products.

Developed by a Team of Experts

Our questionnaires are developed by a multi-disciplinary team of scientists, industry veterans and market research experts with years of experience. These professionals understand that survey questions need to be asked in a way that ensures the answers will directly address the business challenges you face. Once the survey data is collected, this same team creates a unique report that presents the reader with a thorough understanding of the topic and the scientific and business implications of the results based on sophisticated statistical analytics.

Custom Analysis & Research Available

If you'd like to delve deeper into the data from a study, we can always perform custom cross-tabulations or other analysis on your behalf. We can even pose follow-up questions to respondents who answered in a particular way or conduct a custom study to extend your knowledge.

Carefully Selected Survey Participants

When others promote results from their online surveys, they fail to mention the uncontrolled nature of their broadcast email invitations. To provide you with the most valid and accurate results possible, the respondents to our surveys are members of our unique online panel The Science Advisory Board® which consists of more than 50,000 verified life science and biomedical professionals who have agreed to take part in our surveys, focus groups and other market research activities. These respondents are carefully selected based on their professional qualifications, market segments and geographic regions we can even select them based on the products they use and their preferred suppliers.

Complimentary Consulting Provided

With your purchase, we offer one free hour of consultation with our talented team of scientific and business analysts who created the report. During this consultation, we can answer any questions you may have about the survey results and what we believe to be the significant trends affecting the market.

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