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市場調査レポート

RNAシークエンシング:技術と世界市場

RNA Sequencing: Technologies and Global Markets

発行 BCC Research 商品コード 353584
出版日 ページ情報 英文 135 Pages
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RNAシークエンシング:技術と世界市場 RNA Sequencing: Technologies and Global Markets
出版日: 2016年03月07日 ページ情報: 英文 135 Pages
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概要

世界のRNAシークエンシング市場は、2015年の10億米ドルから2020年の約21億米ドルへ、14.9%のCAGR (年間複合成長率) で拡大すると予測されています。

当レポートでは、世界のRNAシークエンシング市場について調査し、世界のRNAシークエンシング・関連技術市場の概要、世界市場の動向分析・CAGR予測、RNAシークエンシングの臨床アプリケーションイニシアチブの分析、共同研究・M&A活動の評価、規制環境とその市場への影響の調査、市場ダイナミクスの分析、特許分析、および主要企業のプロファイルなどを提供しています。

第1章 イントロダクション

第2章 サマリー

第3章 RNAシークエンシングのイントロダクション

  • トランスクリプトミクス
  • トランスクリプトミクス向け技術
  • トランスクリプトミクス向けRNAシークエンシング
  • RNAシークエンシング実験
  • 実験計画
  • RNAシークエンシングの課題
  • RNAシークエンシングの考察・アプリケーション
  • 将来の方向性

第4章 RNAシークエンシング装置

  • 概要
  • RNAシークエンシング向けシークエンシング技術
  • 重要なのRNAシークエンシングプラットフォーム
  • 注目のシークエンシングプラットフォーム
  • ILLUMINA社のプラットフォームに関する技術およびRNAシークエンシング
  • THERMO FISHER社のプラットフォームに関する技術およびRNAシークエンシング
  • PACBIO社のプラットフォームに関する技術およびRNAシークエンシング
  • CDNAラピッドライブラリー調製
  • その他の商用シークエンシングプラットフォーム
  • 新たなシークエンシング技術およびRNAシークエンシングアプリケーション
  • 各プラットフォームの市場シェア
  • RNAシークエンシング装置市場の予測
  • 市場動向

第5章 RNAシークエンシングツール・試薬

  • 概要
  • 市況
  • RNAシークエンシングのオートメーション
  • RNAシークエンシングのサンプル調製
  • RNAの枯渇または改良
  • RNAシークエンシングライブラリー調製

第6章 RNAシークエンシングデータ分析

  • 概要
  • RNAシークエンシング
  • RNAシークエンシングデータ分析の課題
  • RNAシークエンシングデータクラウドサービス
  • RNAシークエンシングデータ分析の独立型ツール
  • RNAシークエンシングデータ分析市場の分析

第7章 RNAシークエンシングサービス市場

  • 概要
  • プラットフォーム専門の認証サービスプロバイダー

第8章 企業プロファイル

  • AGILENT TECHNOLOGIES INC.
  • AMAZON.COM INC.
  • BGI
  • BIO-RAD
  • DNANEXUS INC.
  • GENERAL ELECTRIC COMPANY
  • ILLUMINA INC.
  • NEW ENGLAND BIOLAB INC.
  • OXFORD NANOPORE TEHNOLOGIES LTD.
  • PACIFIC BIOSCIENCES OF CALIFORNIA INC.
  • QIAGEN NV
  • ROCHE HOLDING AG
  • TAKARA BIO INC.
  • THERMO FISHER SCIENTIFIC INC.

第9章 本調査で言及した企業

図表

目次
Product Code: BIO147A

REPORT HIGHLIGHTS

The global RNA-Sequencing market should reach nearly $2.1 billion in 2020, from over $1.0 billion in 2015 registering a compound annual growth rate (CAGR) of 14.9%.

This report provides:

  • An overview of the global markets for RNA sequencing and related technologies.
  • Analyses of global market trends, with data from 2015, estimates for 2016, and projections of CAGRs through 2020.
  • Analysis of RNA sequencing clinical application initiatives.
  • Evaluation of collaboration and merger and acquisition activity.
  • A look at the regulatory environment and its effect on the market.
  • Analyses of the market's dynamics, specifically growth drivers, restraints, and opportunities.
  • Identification of patents with the potential to make an impact in the RNA sequencing industry.
  • Profiles of major players in the industry.

SCOPE AND FORMAT

The geographic scope is global. The RNA-Seq market is complex, consisting of a number of different segments. The market segments are: RNA-Seq instruments; RNA-Seq tools and reagents; RNA-Seq data analysis and RNA-Seq services. Each segment is affected differently by technological and regulatory developments. This report identifies the main factors affecting each segment and forecasts market growth, future trends and product development in every major market segment. Market forecasts are given for the years 2015, 2016 and 2020.

The report is organized by presenting the core segment (sequencing instruments) first, followed by its derivative segments (tools and reagents, data analysis, services). The development of sequencing instruments is vital for RNA-Seq development; thus sequencing instruments segment is classified as the core segment. However, it does not suggest that the derivative segments are not important. In fact, the RNA-Seq instruments segment is neither the biggest nor the fastest growing among the four segments. The instruments segment, however, provides the infrastructure for the health and growth of the RNA-Seq market as a whole.

ANALYST'S CREDENTIALS

Dr. Faqing Yuan is a biomedical technology commercialization expert. He has more than 10 years of experience as a bench scientist specializing in RNA biochemistry, bio-nanotechnology and virology. He is the author of a number of scientific publications. He also holds an MBA degree from Queen's University in Kingston, Canada. He is the author of the BCC Research report, BIO127A RNAi Technologies and Global Markets.

Table of Contents

CHAPTER 1 - INTRODUCTION

  • STUDY GOALS AND OBJECTIVES
  • REASONS FOR DOING THE STUDY
  • INTENDED AUDIENCE
  • SCOPE AND FORMAT
  • METHODOLOGY AND INFORMATION SOURCES
  • ANALYST'S CREDENTIALS
  • RELATED BCC RESEARCH REPORTS
  • BCC RESEARCH WEBSITE
  • DISCLAIMER

CHAPTER 2 - SUMMARY

  • SUMMARY TABLE GLOBAL RNA-SEQ MARKET BY SEGMENT, THROUGH 2020 ($ MILLIONS)
  • SUMMARY FIGURE GLOBAL RNA-SEQ MARKET TRENDS BY SEGMENT, 2014-2020 ($ MILLIONS)

CHAPTER 3 - INTRODUCTION ON RNA-SEQ

  • TRANSCRIPTOMICS
    • TABLE 1: TYPES OF RNAS IN CELLS
    • TABLE 2: TRANSCRIPTOMICS INSIGHTS
  • TECHNOLOGIES FOR TRANSCRIPTOMICS
    • FIGURE 1: COST OF SEQUENCING ONE RAW MEGABASE OF DNA
    • FIGURE 2: COST OF SEQUENCING ONE HUMAN GENOME
  • RNA-SEQ FOR TRANSCRIPTOMICS
    • TABLE 3: COMPARISON OF TRANSCRIPTOMICS METHODS
  • RNA-SEQ EXPERIMENT
    • FIGURE 3: GENERIC RNA-SEQ EXPERIMENT WORKFLOW
  • EXPERIMENTAL DESIGN
    • FIGURE 4: RNA-SEQ EXPERIMENTS FOR TRANSCRIPTOMICS
    • Establish the Primary Experimental Objective
      • TABLE 4: RNA-SEQ ANNOTATION/DGE OPTIONS
    • Replication, Depth and Complexity of the Experiment
    • RNA SAMPLE PREPARATION
    • LIBRARY PREPARATION
      • TABLE 5: FUNCTIONAL ELEMENTS IN SEQUENCING ADAPTERS
    • HIGH-THROUGHPUT SEQUENCING
      • Choosing a Sequencing Platform
    • DATA ANALYSIS
  • CHALLENGES FOR RNA-SEQ
    • LIBRARY CONSTRUCTION CHALLENGES
      • TABLE 6: FRAGMENTATION METHODS AND BIAS
    • BIOINFORMATIC CHALLENGES
    • COST VERSUS COVERAGE CHALLENGES
  • RNA-SEQ INSIGHTS AND APPLICATIONS
    • MAPPING GENE AND EXON BOUNDARIES
    • EXTENSIVE TRANSCRIPT COMPLEXITY
    • NOVEL TRANSCRIPTION
    • DEFINING TRANSCRIPTION LEVEL
  • FUTURE DIRECTION

CHAPTER 4 - RNA-SEQUENCING INSTRUMENTS

  • OVERVIEW
  • SEQUENCING TECHNOLOGIES FOR RNA-SEQ
  • NOTABLE RNA-SEQ PLATFORMS
    • TABLE 7: ILLUMINA SEQUENCING INSTRUMENTS
    • TABLE 8: THERMO FISHER SEQUENCING INSTRUMENTS
    • TABLE 9: ROCHE SEQUENCING INSTRUMENTS
    • TABLE 10: PACBIO SEQUENCING INSTRUMENTS
  • SEQUENCING PLATFORMS TO WATCH
    • TABLE 11: SIGNIFICANT PLAYERS IN SEQUENCING MARKET
  • TECHNOLOGY AND RNA-SEQ ON ILLUMINA PLATFORMS
    • SBS SEQUENCING TECHNOLOGY
      • Cluster Generation
      • Sequencing by Synthesis
    • SEQUENCING WORKFLOW
      • TABLE 12: WORKFLOW STEPS FOR SEQUENCING SYSTEM
    • RNA-SEQ APPLICATIONS ON ILLUMINA SEQUENCING PLATFORMS
      • TABLE 13: RNA-SEQ APPLICATIONS ON ILLUMINA PLATFORMS
      • mRNA-Seq on Illumina Instruments
        • TABLE 14: MRNA-SEQ ON ILLUMINA PLATFORMS
      • Total RNA-Seq on Illumina Platforms
        • TABLE 15: TOTAL RNA-SEQ ON ILLUMINA PLATFORMS
      • Targeted RNA-Seq
        • TABLE 16: RECOMMENDED SETUP FOR TARGETED RNA-SEQ ON MISEQ PLATFORMS
      • Small RNA Sequencing
        • TABLE 17: SMALL RNA-SEQ ON ILLUMINA PLATFORMS
      • Ribosome Profiling
        • TABLE 18: RIBOSOMAL PROFILING ON ILLUMINA PLATFORMS
      • Ultra-Low-Input and Single-Cell RNA-Seq
      • Low-Quality and FFPE RNA-Seq
  • TECHNOLOGIES AND RNA-SEQ ON THERMO FISHER PLATFORMS
    • SANGER SEQUENCING
    • ION TORRENT TECHNOLOGY
      • Library Construction
      • Template Prep or Amplification
      • Sequencing
      • Data Analysis
    • RNA-SEQ ON ION TORRENT PLATFORMS
      • TABLE 19: RNA-SEQ APPLICATIONS ON ION SYSTEMS
    • SOLID SEQUENCING PLATFORM
      • TABLE 20: SOLID 5500 SEQUENCING PLATFORM PERFORMANCES
      • SOLiD Total RNA-Seq, Small RNA-Seq and miRNA Profiling
        • FIGURE 5: SOLID RNA-SEQ WORKFLOW
  • TECHNOLOGIES AND RNA-SEQ ON PACBIO PLATFORMS
    • SMRT TECHNOLOGY
    • RNA-SEQ APPLICATIONS ON PACBIO PLATFORMS
      • TABLE 21: PACBIO RNA-SEQ APPLICATIONS
      • Human/Plant/Animal RNA-Seq
        • TABLE 22: PACBIO RNA-SEQ WORKFLOW
    • RNA-SEQ APPLICATIONS ON 454 PLATFORMS
      • FIGURE 6: 454'S DNA SEQUENCER MECHANISM
  • CDNA RAPID LIBRARY PREP
    • LOW-INPUT RNA SAMPLES
      • TABLE 23: WORKFLOW FOR 454 SEQUENCER
  • OTHER COMMERCIAL SEQUENCING PLATFORMS
    • BGI (COMPLETE GENOMICS)
    • GENEPSYS
    • OXFORD NANOPORE
    • QIAGEN (INTELLIGENT BIOSYSTEMS)
  • NEW SEQUENCING TECHNOLOGIES AND RNA-SEQ APPLICATIONS
    • GENIA
    • BASE4 AND HITACHI
    • GNUBIO/BIO-RAD
    • NABSYS
    • STRATOS GENOMICS
    • TWO PORE GUYS
  • MARKET SHARE OF EACH PLATFORM
    • TABLE 24: HIGH-THROUGHPUT INSTRUMENT COMPETITORS BY INSTALLED INSTRUMENT BASE, AS OF DECEMBER 2015 (NUMBER/%)
    • TABLE 25: BENCHTOP INSTRUMENT COMPETITORS BY INSTALLED INSTRUMENT BASE, AS OF DECEMBER 2015 (NUMBER/%)
  • RNA-SEQ INSTRUMENT MARKET PROJECTION
    • TABLE 26: GLOBAL MARKET FOR INSTRUMENTS USED IN DNA SEQUENCING AND RNA-SEQUENCING, THROUGH 2020 ($ MILLIONS)
  • MARKET TRENDS
    • TABLE 27: REQUIREMENTS FOR RNA-SEQ ON SEQUENCING PLATFORMS

CHAPTER 5 - RNA-SEQ TOOLS AND REAGENTS

  • OVERVIEW
  • MARKET LANDSCAPE
  • RNA-SEQ AUTOMATION
    • TABLE 28: NOTABLE LIQUID HANDLING PLATFORMS FOR RNA-SEQ AUTOMATION
    • TABLE 29: RNA SAMPLE AND LIBRARY PREPARATION PLATFORMS
    • NEOPREP FROM ILLUMINA
    • REM E SYSTEM FROM ROCHE
    • ION TORRENT ION CHEF SYSTEM FROM THERMO FISHER
    • SOLID EZ BEAD SYSTEM FROM THERMO FISHER
    • C1 SYSTEM FROM FLUIDIGM
    • QIACUBE FROM QIAGEN
  • RNA-SEQ SAMPLE PREPARATION
    • RNA SAMPLE ISOLATION AND PURIFICATION
      • TABLE 30: LEADING PRODUCTS PRESERVING RNA EXPRESSION PROFILE
      • TABLE 31: LEADING COMMERCIAL EXTRACTION OR PURIFICATION KITS
    • RNA CONCENTRATION AND PURITY DETERMINATION
      • TABLE 32: RNA QUANTIFICATION INSTRUMENT
    • RNA SAMPLE QUALITY CONTROL
      • TABLE 33: RNA INTEGRITY MEASURING INSTRUMENT
      • Agilent 2100 Bioanalyzer
      • QIAxcel Advanced System
  • RNA DEPLETION OR ENRICHMENT
    • RRNA DEPLETION
      • TABLE 34: RRNA DELETION KITS
      • RiboMinus Technology from Thermo Fisher
      • NEBNext rRNA Depletion Kit (Human/Mouse/Rat) from NEB
      • GeneRead rRNA Depletion Kits from Qiagen
      • Ribo-Zero rRNA Removal Kit from Illumina
      • RiboGone from Clontech
    • MRNA ENRICHMENT
      • TABLE 35: MRNA ENRICHMENT KITS
      • MagJET mRNA Enrichment Kit from Thermo Fisher
      • Dynabeads from Thermo Fisher
      • Ambion Poly(A)Purist MAG Kit from Thermo Fisher
      • SideStep mRNA Enrichment Kit from Agilent
      • GeneRead Pure mRNA Kit from Qiagen
  • RNA-SEQ LIBRARY PREPARATION
    • RNA-SEQ LIBRARY PREP KITS FROM ILLUMINA
      • TABLE 36: RNA-SEQ KITS FOR ILLUMINA PLATFORM
    • RNA-SEQ LIBRARY PREP PRODUCTS FROM THERMO FISHER
      • TABLE 37: THERMO FISHER RNA-SEQ PRODUCTS FOR ION TORRENT
      • TABLE 38: THERMO FISHER'S RNA-SEQ LIBRARY PREP KITS FOR SOLID
    • RNA-SEQ LIBRARY PREP KITS FROM ROCHE 454
      • TABLE 39: RNA-SEQ LIBRARY PREP KITS FROM 454
    • RNA-SEQ LIBRARY PREP KITS FROM PACBIO PLATFORM
      • TABLE 40: PACBIO'S RNA-SEQ REAGENTS PRODUCTS
    • RNA-SEQ PRODUCTS FROM NEW ENGLAND BIOLABS
      • TABLE 41: RNA-SEQ PRODUCTS FROM NEW ENGLAND BIOLABS
    • RNA-SEQ LIBRARY PREPARATION PRODUCTS FROM KAPA BIOSYSTEMS
      • TABLE 42: RNA-SEQ KITS FROM KAPA BIOSYSTEMS
    • RNA-SEQ PRODUCTS FROM CLONTECH (TAKARA)
      • TABLE 43: RNA-SEQ PRODUCTS FROM CLONTECH
    • RNA-SEQ PRODUCTS FROM AGILENT
    • RNA-SEQ PRODUCTS FROM QIAGEN
    • RNA-SEQ REAGENTS FROM NIMBLEGEN (ROCHE)
      • TABLE 44: RNA-SEQ REAGENTS FROM NIMBLEGEN
    • MARKET ANALYSIS
      • TABLE 45: AVERAGE CONSUMABLE COST OF RUNNING SEQUENCING MACHINES
      • TABLE 46: GLOBAL MARKET FOR DNA-SEQ AND RNA-SEQ CONSUMABLES, THROUGH 2020 ($ MILLIONS)

CHAPTER 6 - RNA-SEQ DATA ANALYSIS

  • OVERVIEW
    • FIGURE 7: NEXT-GENERATION SEQUENCING DATA ANALYSIS
  • RNA-SEQ DATA ANALYSIS CHALLENGES
    • DATA SOLUTION
    • ALIGNMENT AND ANNOTATION
    • DATA ANALYSIS FOR LONG-READ SEQUENCERS
  • RNA-SEQ DATA CLOUD SERVICES
    • TABLE 47: CLOUD COMPUTING PROVIDERS FOR GENOMICS/RNA-SEQ
  • STAND-ALONE TOOLS FOR RNA-SEQ DATA ANALYSIS
    • TABLE 48: STAND-ALONE RNA-SEQ DATA ANALYSIS TOOLS
  • RNA-SEQ DATA ANALYSIS ON ILLUMINA PLATFORMS
    • BASESPACE
      • TABLE 49: BASESPACE NOTABLE RNA-SEQ APPS
    • RNA-SEQ DATA ANALYSIS ON OTHER PLATFORMS
    • RNA-SEQ DATA ANALYSIS ON ION TORRENT PLATFORMS
    • RNA-SEQ DATA ANALYSIS ON SOLID PLATFORMS
    • RNA-SEQ DATA ANALYSIS ON 454 PLATFORMS
    • RNA-SEQ DATA ANALYSIS ON PACBIO PLATFORMS
  • RNA-SEQ DATA ANALYSIS MARKET ANALYSIS
    • TABLE 50: GLOBAL MARKET FOR RNA-SEQ DATA ANALYSIS, THROUGH 2020 ($ MILLIONS)

CHAPTER 7 - RNA-SEQ SERVICE MARKET

  • OVERVIEW
  • PLATFORM-SPECIFIC CERTIFIED SERVICE PROVIDERS
    • ILLUMINA CERTIFIED SERVICE PROVIDERS (CSPRO)
      • TABLE 51: ILLUMINA CERTIFIED SERVICE PROVIDERS (CSPRO) NORTH AMERICA, AS OF NOVEMBER 2015
      • TABLE 52: ILLUMINA CERTIFIED SERVICE PROVIDERS (CSPRO) EUROPE, AS OF NOVEMBER 2015
      • TABLE 53: ILLUMINA CERTIFIED SERVICE PROVIDERS (CSPRO) ASIA-PACIFIC, AS OF NOVEMBER 2015
    • ION TORRENT CERTIFIED SERVICE PROVIDER PROGRAM
      • TABLE 54: ION TORRENT CERTIFIED SERVICE PROVIDERS, AS OF NOVEMBER 2015
    • SOLID NEXT-GENERATION SEQUENCING ANALYSIS SERVICES
      • TABLE 55: SOLID SEQUENCING SERVICE PROVIDERS, AS OF NOVEMBER 2015
    • NIMBLEGEN CERTIFIED SERVICE PROVIDERS ON 454 PLATFORMS
      • TABLE 56: ROCHE SEQUENCING EFFORTS
      • TABLE 57: NIMBLEGEN CERTIFIED SERVICE PROVIDERS
    • PACIFIC BIOSCIENCES (PACBIO) CERTIFIED SERVICE PROVIDERS
      • TABLE 58: PACBIO CERTIFIED SERVICE PROVIDERS, AS OF NOVEMBER 2015
      • TABLE 59: ADDITIONAL SERVICE PROVIDERS ON PACBIO PLATFORMS, AS OF NOVEMBER 2015
    • AGILENT'S CERTIFIED SERVICE PROVIDERS-TARGET ENRICHMENT
      • TABLE 60: AGILENT CERTIFIED SERVICE PROVIDERS, AS OF NOVEMBER 2015
    • NON-CERTIFIED SERVICE PROVIDERS
      • TABLE 61: NON-CERTIFIED RNA-SEQ PROVIDERS, AS OF NOVEMBER 2015
      • TABLE 62: NON-CERTIFIED, NON-PROFIT SEQUENCING SERVICE PROVIDERS, AS OF NOVEMBER 2015
      • TABLE 63: NON-CERTIFIED, COMMERCIAL SEQUENCING SERVICE PROVIDERS, AS OF NOVEMBER 2015
    • NOTABLE SERVICE PROVIDERS
      • TABLE 64: SEQUENCING SERVICE PROVIDERS CERTIFIED BY MULTIPLE PROGRAMS, AS OF NOVEMBER 2015
      • AMBRY GENETICS
      • BASECLEAR
      • BECKMAN COULTER GENOMICS
      • BGI
      • CEGAT
      • DNA LINK
      • DNAVISION
      • EXIQON A/S
      • EXPRESSION ANALYSIS (Q2 SOLUTIONS)
      • FASTERIS
      • GATC
      • GENEWIZ
      • INTEGRAGEN
      • PERKINELMER INC
      • SEQLL
      • SEQWRIGHT (NOW GE HEALTHCARE)
    • MARKET ANALYSIS
      • TABLE 65: GLOBAL MARKET FOR RNA-SEQ RESEARCH SERVICES, THROUGH 2020 ($ MILLIONS)

CHAPTER 8 - COMPANY PROFILES

  • AGILENT TECHNOLOGIES INC.
  • AMAZON.COM INC.
  • BGI
  • BIO-RAD
  • DNANEXUS INC.
  • GENERAL ELECTRIC COMPANY
  • ILLUMINA INC.
  • NEW ENGLAND BIOLAB INC.
  • OXFORD NANOPORE TEHNOLOGIES LTD.
  • PACIFIC BIOSCIENCES OF CALIFORNIA INC.
  • QIAGEN NV
  • ROCHE HOLDING AG
  • TAKARA BIO INC.
  • THERMO FISHER SCIENTIFIC INC.

CHAPTER 9 - COMPANIES MENTIONED IN THE REPORT

  • ACGT INC.
  • ADVANCED GENOMICS
  • AFFILIATED GENETICS INC.
  • AGRESEARCH LIMITED
  • AGYSIS BIOLABS
  • AITBIOTECH
  • ALACRIS
  • ALPHABIOLABS
  • ALTHEA DX
  • AMBRY GENETICS
  • AMPLICON EXPRESS
  • AMRESCO
  • APPLIED BIOLOGICAL MATERIAL INC.
  • AROS APPLIED BIOTECHNOLOGY A/S
  • ARRAYXPRESS INC.
  • ASURAGEN INC.
  • BIORELIANCE
  • CD GENOMICS
  • CEGAT GMBH
  • CENTOGENE AG
  • CHUNLAB INC.
  • CLARITAS GENOMICS
  • CLC BIO
  • CLINICAL GENOMICS
  • CLONTECH LABORATORIES INC.
  • COFACTOR GENOMICS
  • COGENTECH
  • CREATIVE GENOMICS
  • CUROVERSE
  • CYPHER GENOMICS
  • DECODE GENETICS
  • DELTAGENE MOLECULAR DIAGNOSTIC
  • DENA LIFE SCIENCE INC.
  • DNA ANALYSIS LLC.
  • DNA LINK INC.
  • DNANEXUS
  • DNAVISION
  • EAGLE GENOMICS
  • EDGEBIO
  • ELIM BIOPHARMACEUTICALS
  • ENSIGNA BIOSYSTEMS INC.
  • EPICENTRE
  • EPOCH LIFE SCIENCE
  • EPPENDORF
  • ERA7 BIOINFORMATICS
  • EUREKA GENOMICS
  • EUROFINS MWG OPERON
  • EXIQON
  • EXPRESSION ANALYSIS
  • FASTERIS SA
  • FAVORGEN BIOTECH COMPANY
  • FIRST BASE LABORATORIES
  • FLUIDIGM
  • FUNCTIONAL BIOSCIENCES
  • GATC BIOTECH AG
  • GE HEALTHCARE
  • GENAPSYS
  • GENE DX
  • GENEAID BIOTECH
  • GENEBLITZ
  • GENECHRON
  • GENERGY BIOTECHNOLOGY
  • GENES DIFFUSION
  • GENESEEK
  • GENESTACK
  • GENETIC VISIONS INC.
  • GENETICLAB CO. LTD.
  • GENEWIZ INC.
  • GENIA TECHNOLOGIES
  • GENOMA
  • GOOGLE GENOME CLOUD
  • GENOME INTERNATIONAL CORP.
  • GENOMED
  • GENOSPACE
  • GENOTECH CORP.
  • GEOSPIZA
  • GIRIHLET INC.
  • GLOBUS GENOMICS
  • GNUBIO
  • HAMILTON ROBOTICS
  • HOKKAIDO SYSTEM SCIENCE CO., LTD
  • IGA TECHNOLOGY SERVICES SRL
  • ILLUMINA
  • IMGM LABORATORIES GMBH
  • INGENUITY
  • INQABA BIOTEC
  • INTEGRAGEN
  • INTELLIGENT BIO-SYSTEM
  • KAPA BIOSYSTEMS
  • KEYGENE
  • LAB FELLOWS INC.
  • LABCORP CLINICAL TRIALS
  • LARAGEN
  • LC SCIENCES
  • LGC GENOMICS
  • LI-COR BIOSCIENCES
  • LIFESEQUENCING SL
  • LOFSTRAND LABS
  • LONE STAR LABS INC.
  • LUCIGEN CORP.
  • MACROGEN
  • MCLAB
  • MICROSYNTH AG
  • MOGENE, LC
  • NABSYS
  • NEW ENGLAND BIOLABS
  • NIMBLEGEN
  • NIMGENETICS
  • NORGEN BIOTEK CORP
  • OMEGA BIOSERVICES
  • OMICIA
  • ONECODEX
  • OTOGENETICS CORP.
  • OXFORD NANOPORE TECHNOLOGIES
  • PACIFIC BIOSCIENCES
  • PARTEK
  • PERSONALIS
  • PROMEGA
  • QIAGEN
  • RETROGEN
  • RIKENGENESIS CO. LTD.
  • RNASSIST
  • ROCHE SEQUENCING
  • SELAH GENOMICS
  • SEQLL INC.
  • SEQMATIC
  • SEQUENCEBASE
  • SEQUENSYS
  • SEQUETECH
  • SEQUISERVE
  • SEQXCEL
  • SERVICEXS B.V.
  • SEVEN BRIDGES GENOMICS
  • SHIMADZU
  • SIGMA-ALDRICH
  • SINOGENOMAX CO. LTD.
  • SISTEMAS GENOMICOS
  • SNP GENETICS INC.
  • SOLVEBIO
  • SOLVIAS
  • SORENSON GENOMICS
  • SOURCE BIOSCIENCE
  • SPIRAL GENETICS
  • STARSEQ
  • STRAND NGS
  • STRATOS GENOMICS
  • SYAPSE
  • SYNERGENE BIOTECH GMBH
  • SYNTHETIC GENOMICS
  • SYSTEM BIOSCIENCES
  • TAKARA BIO INC.
  • TAUERET LABORATORIES
  • TECAN
  • TEPNEL PHARMACEUTICAL SERVICES
  • THERMO FISHER SCIENTIFIC
  • TRAITGENETICSGMBH
  • TUTE GENOMICS
  • TWO PORE GUYS
  • VBC-BIOTECH
  • VIA GENETICS
  • WAFERGEN
  • WUXI APPTEC
  • WUXI NEXTCODE
  • YORKSHIRE BIOSCIENCE
  • YOURGENE BIOSCIENCE
  • ZOETIS GENETICS
  • ZS GENETICS
  • ZYMO RESEARCH

LIST OF TABLES

  • SUMMARY TABLE GLOBAL RNA-SEQ MARKET BY SEGMENT, THROUGH 2020 ($ MILLIONS)
    • TABLE 1: TYPES OF RNAS IN CELLS
    • TABLE 2: TRANSCRIPTOMICS INSIGHTS
    • TABLE 3: COMPARISON OF TRANSCRIPTOMICS METHODS
    • TABLE 4: RNA-SEQ ANNOTATION/DGE OPTIONS
    • TABLE 5: FUNCTIONAL ELEMENTS IN SEQUENCING ADAPTERS
    • TABLE 6: FRAGMENTATION METHODS AND BIAS
    • TABLE 7: ILLUMINA SEQUENCING INSTRUMENTS
    • TABLE 8: THERMO FISHER SEQUENCING INSTRUMENTS
    • TABLE 9: ROCHE SEQUENCING INSTRUMENTS
    • TABLE 10: PACBIO SEQUENCING INSTRUMENTS
    • TABLE 11: SIGNIFICANT PLAYERS IN SEQUENCING MARKET
    • TABLE 12: WORKFLOW STEPS FOR SEQUENCING SYSTEM
    • TABLE 13: RNA-SEQ APPLICATIONS ON ILLUMINA PLATFORMS
    • TABLE 14: MRNA-SEQ ON ILLUMINA PLATFORMS
    • TABLE 15: TOTAL RNA-SEQ ON ILLUMINA PLATFORMS
    • TABLE 16: RECOMMENDED SETUP FOR TARGETED RNA-SEQ ON MISEQ PLATFORMS
    • TABLE 17: SMALL RNA-SEQ ON ILLUMINA PLATFORMS
    • TABLE 18: RIBOSOMAL PROFILING ON ILLUMINA PLATFORMS
    • TABLE 19: RNA-SEQ APPLICATIONS ON ION SYSTEMS
    • TABLE 20: SOLID 5500 SEQUENCING PLATFORM PERFORMANCES
    • TABLE 21: PACBIO RNA-SEQ APPLICATIONS
    • TABLE 22: PACBIO RNA-SEQ WORKFLOW
    • TABLE 23: WORKFLOW FOR 454 SEQUENCER
    • TABLE 24: HIGH-THROUGHPUT INSTRUMENT COMPETITORS BY INSTALLED INSTRUMENT BASE, AS OF DECEMBER 2015 (NUMBER/%)
    • TABLE 25: BENCHTOP INSTRUMENT COMPETITORS BY INSTALLED INSTRUMENT BASE, AS OF DECEMBER 2015 (NUMBER/%)
    • TABLE 26: GLOBAL MARKET FOR INSTRUMENTS USED IN DNA SEQUENCING AND RNA-SEQUENCING, THROUGH 2020 ($ MILLIONS)
    • TABLE 27: REQUIREMENTS FOR RNA-SEQ ON SEQUENCING PLATFORMS
    • TABLE 28: NOTABLE LIQUID HANDLING PLATFORMS FOR RNA-SEQ AUTOMATION
    • TABLE 29: RNA SAMPLE AND LIBRARY PREPARATION PLATFORMS
    • TABLE 30: LEADING PRODUCTS PRESERVING RNA EXPRESSION PROFILE
    • TABLE 31: LEADING COMMERCIAL EXTRACTION OR PURIFICATION KITS
    • TABLE 32: RNA QUANTIFICATION INSTRUMENT
    • TABLE 33: RNA INTEGRITY MEASURING INSTRUMENT
    • TABLE 34: RRNA DELETION KITS
    • TABLE 35: MRNA ENRICHMENT KITS
    • TABLE 36: RNA-SEQ KITS FOR ILLUMINA PLATFORM
    • TABLE 37: THERMO FISHER RNA-SEQ PRODUCTS FOR ION TORRENT
    • TABLE 38: THERMO FISHER'S RNA-SEQ LIBRARY PREP KITS FOR SOLID
    • TABLE 39: RNA-SEQ LIBRARY PREP KITS FROM 454
    • TABLE 40: PACBIO'S RNA-SEQ REAGENTS PRODUCTS
    • TABLE 41: RNA-SEQ PRODUCTS FROM NEW ENGLAND BIOLABS
    • TABLE 42: RNA-SEQ KITS FROM KAPA BIOSYSTEMS
    • TABLE 43: RNA-SEQ PRODUCTS FROM CLONTECH
    • TABLE 44: RNA-SEQ REAGENTS FROM NIMBLEGEN
    • TABLE 45: AVERAGE CONSUMABLE COST OF RUNNING SEQUENCING MACHINES
    • TABLE 46: GLOBAL MARKET FOR DNA-SEQ AND RNA-SEQ CONSUMABLES, THROUGH 2020 ($ MILLIONS)
    • TABLE 47: CLOUD COMPUTING PROVIDERS FOR GENOMICS/RNA-SEQ
    • TABLE 48: STAND-ALONE RNA-SEQ DATA ANALYSIS TOOLS
    • TABLE 49: BASESPACE NOTABLE RN: -SEQ APPS
    • TABLE 50: GLOBAL MARKET FOR RNA-SEQ DATA ANALYSIS, THROUGH 2020 ($ MILLIONS)
    • TABLE 51: ILLUMINA CERTIFIED SERVICE PROVIDERS (CSPRO) NORTH AMERICA, AS OF NOVEMBER 2015
    • TABLE 52: ILLUMINA CERTIFIED SERVICE PROVIDERS (CSPRO) EUROPE, AS OF NOVEMBER 2015
    • TABLE 53: ILLUMINA CERTIFIED SERVICE PROVIDERS (CSPRO) ASIA-PACIFIC, AS OF NOVEMBER 2015
    • TABLE 54: ION TORRENT CERTIFIED SERVICE PROVIDERS, AS OF NOVEMBER 2015
    • TABLE 55: SOLID SEQUENCING SERVICE PROVIDERS, AS OF NOVEMBER 2015
    • TABLE 56: ROCHE SEQUENCING EFFORTS
    • TABLE 57: NIMBLEGEN CERTIFIED SERVICE PROVIDERS
    • TABLE 58: PACBIO CERTIFIED SERVICE PROVIDERS, AS OF NOVEMBER 2015
    • TABLE 59: ADDITIONAL SERVICE PROVIDERS ON PACBIO PLATFORMS, AS OF NOVEMBER 2015
    • TABLE 60: AGILENT CERTIFIED SERVICE PROVIDERS, AS OF NOVEMBER 2015
    • TABLE 61: NON-CERTIFIED RNA-SEQ PROVIDERS, AS OF NOVEMBER 2015
    • TABLE 62: NON-CERTIFIED, NON-PROFIT SEQUENCING SERVICE PROVIDERS, AS OF NOVEMBER 2015
    • TABLE 63: NON-CERTIFIED, COMMERCIAL SEQUENCING SERVICE PROVIDERS, AS OF NOVEMBER 2015
    • TABLE 64: SEQUENCING SERVICE PROVIDERS CERTIFIED BY MULTIPLE PROGRAMS, AS OF NOVEMBER 2015
    • TABLE 65: GLOBAL MARKET FOR RNA-SEQ RESEARCH SERVICES, THROUGH 2020 ($ MILLIONS)

LIST OF FIGURES

  • SUMMARY FIGURE: GLOBAL RNA-SEQ MARKET TRENDS BY SEGMENT, 2014-2020 ($ MILLIONS)
    • FIGURE 1: COST OF SEQUENCING ONE RAW MEGABASE OF DNA
    • FIGURE 2: COST OF SEQUENCING ONE HUMAN GENOME
    • FIGURE 3: GENERIC RNA-SEQ EXPERIMENT WORKFLOW
    • FIGURE 4: RNA-SEQ EXPERIMENTS FOR TRANSCRIPTOMICS
    • FIGURE 5: SOLID RNA-SEQ WORKFLOW
    • FIGURE 6: 454'S DNA SEQUENCER MECHANISM
    • FIGURE 7: NEXT-GENERATION SEQUENCING DATA ANALYSIS
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