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セルベースアッセイ:各種技術および世界の市場

Cell-based Assays: Technologies and Global Markets

発行 BCC Research 商品コード 196807
出版日 ページ情報 英文 219 Pages
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セルベースアッセイ:各種技術および世界の市場 Cell-based Assays: Technologies and Global Markets
出版日: 2017年07月13日 ページ情報: 英文 219 Pages
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概要

世界のセルベースアッセイの市場は2016年から2021年にかけて10.6%のCAGR (年間複合成長率) で推移し、2015年の152億ドルから、2016年には171億ドル、2021年には284億ドルの規模に成長すると予測されています。

当レポートでは、セルベースアッセイの技術と市場を調査し、セルベースアッセイの定義と概要、構成技術・関連技術の動向、関連技術・ツール・試薬の市場規模の推移と予測、主要地域・国別の動向、特許状況、主要企業のプロファイルなどをまとめています。

第1章 イントロダクション

第2章 サマリー・ハイライト

第3章 概要

  • イントロダクション
  • 創薬
  • 概要:セルベースアッセイ
  • 創薬向けツール
    • ハイコンテンツスクリーニング
    • セルベーススクリーニング
    • 増殖アッセイ
    • セルベースアッセイの概念実証
    • セルベースアッセイと技術動向

第4章 創薬のためのセルベースアッセイ

  • ADME/TOXスクリーニングのためのセルベースアプローチ
    • 市場機会
    • ADME・毒性スクリーニング
    • 多重アレイセルベースアッセイ
    • セルベースバイオロジカルアッセイ
    • セルベースアッセイ向けハイスループットイメージングベースプラットフォーム
    • ラベルフリーのセルラーアッセイ:創薬と関連ある将来
  • 総論

第5章 セルベースアッセイ:現在の技術

  • セルベースアッセイ開発の影響因子
  • レポーター遺伝子技術
  • タンパク質間相互作用の研究のためのセルベースアッセイ
  • セルベースの相互作用検出法 (PCA:Protein-fragment Complementation Assay)
  • カルシウムシグナリングの測定
  • セルベースラベルフリーアプローチ
  • 自動化・小型化
  • セルパターニング
  • セルベースアッセイと生理的関連性
  • セルベースアッセイと多重化
  • ウルトラハイスループットスクリーニング
  • PATHHUNTERアッセイの開発
  • ハイコンテンツスクリーニング技術
  • 創薬における治験薬(IND)研究
  • プロドラッグ戦略
  • 分子モデリング
  • サマリー
  • 新技術
  • 総論

第6章 セルベースアッセイの商業化

  • セルベースアッセイの役割
    • 創薬・セルベースアッセイ
    • 市場導入の機会
    • 細胞増殖の測定
    • 細胞増殖アッセイ提供企業
    • 幹細胞・免疫細胞による治療に向かう動き
    • セルベーススクリーニングアッセイ
    • オーファン受容体
  • サマリー

第7章 世界のセルベースアッセイおよび計装市場

  • 現在の市場概要
  • セルベースアッセイ
  • セルベースアッセイ市場
  • セルバイオロジー試薬
  • ハイスループットスクリーニング
  • 創薬技術市場
  • ライフサイエンスツール&試薬の市場
  • 細胞培養市場
  • 細胞培養試薬の世界市場
  • セルベースアッセイ市場の成長
  • 基礎研究向けセルラーアッセイ市場
  • ADME・毒物学市場
  • 創薬向けセルベースアッセイ
  • ADME-毒物検査市場
  • セルベースアッセイの各種タイプ
  • ハイコンテンツスクリーニング機器市場
  • ラベルフリー検出市場
  • マイクロプレート用機器・消耗品
  • セルベースアッセイによる変化
  • セルベースアッセイの将来性
  • 研究目的のセルベースアッセイ
  • セルベースアッセイ:イオンチャネルのスクリーニング
  • ラベルフリー検出
  • 総論

第8章 市場分析:地域別

  • 世界市場
  • サマリー
  • 米国
  • 欧州
  • 新興経済圏における創薬
  • セルベースアッセイの進化

第9章 企業プロファイル

第10章 セルベースアッセイの法的側面

  • 知的財産権の状況

第11章 参考資料

図表

このページに掲載されている内容は最新版と異なる場合があります。詳細はお問い合わせください。

目次
Product Code: BIO080C

The global market for cell-based assays reached $15.2 billion in 2015. This market is expected to increase from $17.1 billion in 2016 to nearly $28.4 billion in 2021 at a compound annual growth rate (CAGR) of 10.6% for 2016-2021.

Report Includes

  • An overview of the global markets and related technologies for cell-based assays.
  • Analyses of global market trends, with data from 2015 and 2016, and projections of compound annual growth rates (CAGRs) through 2021.
  • Examinations of major issues involved in the research and development (R&D) of more effective cell-based approaches, for drug discovery and absorption, distribution, metabolism, and excretion (ADME)/ toxicity assays in development and in use.
  • The current market status of cell-based assays in terms of strengths, weaknesses, opportunities and threats facing various assays and developments already on the market.
  • Discussion of current issues and trends affecting the industry, and costs and other factors influencing demand.
  • Coverage of new technologies, trends, alliances, and mergers.
  • Profiles of major players in the industry.

Report Scope

This report is an update on the earlier report: Cell-based Assays: Technologies and Global Markets. It reviews global markets for cell-based assays and new developments and forecasts trends for use of these assays for drug discovery, safety and toxicology through 2021. The report includes important assays, technologies and the latest developments and market share by assay type and company, with a special emphasis on the U.S. market. Statistical information on the types of cancers prevalent worldwide is also included. The report also includes current issues and trends affecting the industry, costs and factors influencing demand. It covers products in development, new technologies, trends, and alliances and mergers. The report offers market data by segment and region. It also provides market trends with respect to drivers, restraints and opportunities.

Analyst Credentials

Usha Nagavarapu is an experienced pharmaceutical professional with business development experience. She has preclinical, alliance management, discovery and technology development and marketing experience. Her strong focus areas include oncology and cardiovascular disease, with expertise in molecular and cell biology and complex cell-based biological assays for drug discovery, in vitro and in vivo screening, in vivo model development and pharmacokinetics. She has experience working with early start-ups.

Table of Contents

Chapter 1: Introduction

  • Study Goals and Objectives
  • Reasons for Doing This Study
  • Scope of Report
  • Intended Audience
  • Methodology
  • Geographic Breakdown
  • Analyst's Credentials
  • Related BCC Research Reports

Chapter 2: Summary and Highlights

Chapter 3: Overview

  • Introduction
  • Drug Discovery
    • High-content Screening
    • Data Analysis
  • Overview: Cell-based Assays
  • Tools for Drug Discovery
    • High-content Screening
    • Cell-based Screening
    • Proliferation Assays
    • Proof of Concept for Cell-based Assays
    • Cell-based Assays and Technology Trends

Chapter 4: Assays for Drug Discovery

  • Cell-based Approaches for ADME/Tox Screening
    • Market Opportunity
    • ADME and Toxicity Screening
    • Multiplexed Cell-based Assays
    • Cell-based Biological Assays
    • High-throughput Imaging-based Platform for Cell-based Assays
    • Cell Assays in Today's Drug Discovery Process
    • Label-free Cellular Assays: The Relevant Future of Drug Discovery
  • Conclusions

Chapter 5: Cell-based Assays: Current Technologies

  • Factors in Cell-based Assay Development
  • Reporter Gene Technology
  • Cell-based Assays for Studying Protein-Protein Interactions
  • Cell-based Protein-Fragment Complementation Assays
  • Measuring Calcium Signaling
  • Cell-based Label-free Approaches
  • Automation and Miniaturization
  • Cell Patterning
  • Cell-based Assays and Physiological Relevance
  • Cell-based Assays and Multiplexing
    • Developing Reporter Assays
    • Reporter Assays and Multiplexing
  • Ultra-high-throughput Screening
  • Development of PathHunter Assay
  • High-content Screening Technology
    • Imaging Cells for Cell-based Assays
    • Microscopic Visualization of Cells
    • Quantum Dots
    • Label-free Imaging
  • Investigational New Drug (IND) Studies in Drug Development
    • Role of ADME in Drug Design
  • Prodrug Strategies
  • Molecular Modeling
  • Summary
    • Limitations of Cell-based Assays in the Process of Risk Assessment
    • Bottlenecks in Cell-based Screening.
    • Methods to Improve Throughput in Cell-based Assays
  • New Technologies
    • DataChip
    • BIND Technology
    • Miniaturization of Biological Assays
    • Microfluidic Cell Culture Systems for Drug Research
  • Conclusion

Chapter 6: Commercialization of Cell-based Assays

  • Role of Cell-based Assays
    • Drug Discovery and Cell-based Assays
    • Opportunities for Market Adoption
    • Measuring Cell Proliferation
    • Companies Offering Cell Proliferation Assays
    • Move Toward Therapies with Stem and Immune Cells
    • Cell-based Screening Assays
    • Orphan Receptors
  • Summary

Chapter 7: Global Cell-based Assay and Instrumentation Market

  • Current Market Overview
  • Cell-based Assays
  • Cell-based Assay Market
    • Market Dynamics
    • Market Drivers
    • Cell-based Assays for Preclinical Development
  • Cell Biology Reagents
  • High-throughput Screening
    • Advantages of HTS Assays
    • Major Drivers
  • Drug Discovery Technology Market
  • Market for Life Sciences Tools and Reagents
  • Cell Culture Market
    • Cell Culture Reagent Market
  • Global Market for Cell Culture Reagents
    • Three-dimensional Cell Culture Market
  • Cell-based Assays Market Growth
    • Market Demand
  • Cell-based Assays: Basic Research
  • Market for Cellular Assays in Basic Research.
    • GE Healthcare and Products
    • Cell Proliferation Fluorescence Assay
    • In vitro Toxicity Testing
    • In vitro Skin Irritation Testing
  • ADME and Toxicology Market
    • In vitro Predictive Toxicology
  • Cell-based Assays for Drug Discovery
  • ADME-Toxicology Testing Market
    • DiscoverX
    • ADME: Tools and Technologies
    • ADME Studies for FDA Submissions
    • Market Players
    • New Developments
    • In vitro Inflammation Models
    • Multiplex Assays for GPCR Signaling
  • Types of Cell-based Assays
    • HCS Market Drivers
    • Molecular Devices
    • High-Content Screening Kits
  • High-content Screening Instrumentation Market
    • Flow Cytometers
  • Label-free Detection Market
  • Microplate Instrumentation and Supplies
  • Challenges with Cell-based Assays
  • Future of Cell-based Assays
  • Cell-based Assays for Research Purposes
    • G Protein-Coupled Receptors
    • Key Facts
  • Cell-based Assays: Screening Ion Channels
  • Label-free Detection
    • Companies
    • CellSensor Assays
    • LanthaScreen Assays
    • Molecular Devices
  • Conclusion

Chapter 8: Global Regional Markets

  • Global Market for Cell-based Assays
    • Cell-based Assays in the Leading Emerging Markets
  • Summary
  • U.S. Market
  • Global Market Overview
  • European Market
  • Drug Discovery in the Emerging Economies
    • Drug Discovery in India and China
  • Advances in Cell-based Assays
    • Contract Research Organizations and Cell-based Assays
    • Outlook

Chapter 9: Company Profiles

Chapter 10: Legal Aspects of Cell-based Assays

  • Intellectual Property Landscape for Cell-based Assays
    • Latest News, Alliances and Mergers
    • Label-free Technologies
    • Summary and Outlook

Appendix: Bibliography

About BCC Research

  • About BCC Research
  • BCC Membership
  • BCC Custom Research

List of Tables

  • Summary Table: Global Market for Cell-based Assays, Through 2021 ($ Millions)
  • Table 1 Cell-Based Assays and Uses
  • Table 2 Types of Cell-based Assays
  • Table 3 Apoptotic Markers
  • Table 4 Proof-of-Concept for Cell-based Assays
  • Table 5 Global Market and Forecast for Cell-based Assays, Through 2021 ($ Millions)
  • Table 6 Biological Assay Systems for the Evaluation of Cytochrome P450 Enzyme Isoforms
  • Table 7 Hepatocyte Assay Systems
  • Table 8 ADME Assays
  • Table 9 Common Toxicity Assays
  • Table 10 Traditional Methods of ADME/Tox Testing
  • Table 11 Conventional in vitro ADME/Tox Screening Methods
  • Table 12 Label-free Assays and Applications
  • Table 13 Factors for Cell-based Assay Development
  • Table 14 Approaches to Cell-based Systems for Drug Screening
  • Table 15 Current Confocal HCS Platforms
  • Table 16 Widefield HCS Platforms
  • Table 17 Studies for Filing an IND
  • Table 18 Studies for Clinical Filings
  • Table 19 Existing Technologies
  • Table 20 Biological Applications for HCA
  • Table 21 Global Market for Cell Biology Reagents and Tools, Through 2021 ($ Millions)
  • Table 22 Global HTS Market, Through 2021 ($ Millions)
  • Table 23 HTS Technologies: Key Companies
  • Table 24 Global Market for Drug Discovery Technologies, Through 2021 ($ Millions)
  • Table 25 Key Companies for Drug Discovery Technologies
  • Table 26 Global Market for Reagents and Tools Used in Life Sciences Research, Through 2021 ($ Millions)
  • Table 27 Global Market for Cell Culture, Through 2021 ($ Millions)
  • Table 28 Global Cell Culture Reagent Types
  • Table 29 Global Market for Cell Culture Reagents, Through 2021 ($ Millions)
  • Table 30 U.S. Market for Cell Culture, Through 2021 ($ Millions)
  • Table 31 Global Market for 3D Cell Culture, Through 2019 ($ Millions)
  • Table 32 3D Cell Culture
  • Table 33 Cell-based Assay companies
  • Table 34 Cell-based Assay Market
  • Table 35 Global Market for Cell-Based Assays, Through 2021 ($ Millions)
  • Table 36 Limitations of Cell-Based Assays
  • Table 37 Global Market for Cell-based Assays Used in Basic Research, Through 2021 ($ Millions)
  • Table 38 In vitro Toxicology Testing
  • Table 39 Global 3D Cell Culture, Through 2021 ($ Millions)
  • Table 40 Global Market for Specialized Cell-based Assays used in Drug Discovery, Through 2021 ($ Millions)
  • Table 41 In vitro Predictive Toxicology Assays
  • Table 42 3D Microtissue and Spheroid Models
  • Table 43 Global Market for ADME Assays, Through 2021 ($ Millions)
  • Table 44 Key Companies
  • Table 45 HCS Market: Major Companies
  • Table 46 Molecular Devices: Products
  • Table 47 HCS System Platforms
  • Table 48 Millipore Products: Applications
  • Table 49 Global Market for High-content Screening Instruments, Through 2018 ($ Millions)
  • Table 50 Key Flow Cytometry Companies
  • Table 51 Key GPCR-targeting Drugs
  • Table 52 Key Companies with GPCR Products
  • Table 53 Omeros: GPCRs and Indications
  • Table 54 Assay Methods to Study GPCRs
  • Table 55 GPCR Primary Screening Assays
  • Table 56 Thermo Fisher's Products
  • Table 57 Thermo Fisher's Cell-based Technologies
  • Table 58 Global Market for Cell-based Assays, by Region, Through 2021 ($ Millions)
  • Table 59 U.S. Market for Cell-based Assays, Through 2021 ($ Millions)
  • Table 60 Key Growth Drivers of the Market for Cell-based Assays
  • Table 61 European Market for Cell-based Assay, Through 2021 ($ Millions)
  • Table 62 Chinese Drug Discovery Outsourcing Market, Through 2021 ($ Millions)
  • Table 63 Indian Drug Discovery Market, Through 2021 ($ Millions)

List of Figures

  • Summary Figure: Global Market for Cell-based Assays, 2015-2021 ($ Millions)
  • Figure 1 Drug Discovery Process and Steps
  • Figure 2 Global Market and Forecast for Cell-based Assays, 2015-2021 ($ Millions)
  • Figure 3 Global Market for Cell Biology Reagents and Tools, 2012-2021 ($ Millions)
  • Figure 4 Global Market for Drug Discovery Technologies, 2013-2021 ($ Millions)
  • Figure 5 Global Market for Reagents and Tools used in Life Sciences Research, 2016 and 2021 ($ Millions)
  • Figure 6 Global Market for Cell Culture, 2013-2021 ($ Millions)
  • Figure 7 Global Market for Cell Culture Reagents, 2013-2021 ($ Millions)
  • Figure 8 U.S. Market for Cell Culture, 2013-2021 ($ Millions)
  • Figure 9 Global Market for 3D Cell Culture Reagents, 2013-2019 ($ Millions)
  • Figure 10 Global Market for Cell-Based Assays, 2013-2021 ($ Millions)
  • Figure 11 Global Market for Cell-based Assays Used in Basic Research, 2013-2021 ($ Millions)
  • Figure 12 Global 3D Cell Culture, 2016 and 2021 ($ Millions)
  • Figure 13 Global Market for Specialized Cell-based Assays used in Drug Discovery, 2013-2021 ($ Millions)
  • Figure 14 Global Market for ADME Assays, 2013-2021 ($ Millions)
  • Figure 15 Global Market for High-content Screening Instruments, 2013 and 2018 ($ Millions)
  • Figure 16 Global Market for Cell-Based Assays, by Region, 2013-2021 ($ Millions)
  • Figure 17 U.S. Market for Cell-based Assays, 2013-2021 ($ Millions)
  • Figure 18 European Market for Cell-Based Assays, 2013-2021 ($ Millions)
  • Figure 19 Chinese Drug Discovery Outsourcing Market, 2013-2021 ($ Millions)
  • Figure 20 Indian Drug Discovery Market, 2016 and 2021 ($ Millions)
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