再生医療：骨・関節への応用

世界の骨・関節再生医療の市場規模は、2022年の96億米ドル、2023年の107億米ドルから、2023年から2028年にかけての予測期間中は12.1%のCAGRで推移し、2028年には189億米ドルの規模に成長すると予測されています。

生体材料技術の部門は、2023年の64億米ドルから、11.3％のCAGRで推移し、2028年には110億3,000万米ドルの規模に成長すると予測されています。また、組織工学の部門は、2023年の27億米ドルから、13.3%のCAGRで推移し、2028年には50億4,000万米ドルの規模に成長すると予測されています。

当レポートでは、世界の骨・関節再生医療の市場を調査し、市場および技術の背景、市場影響因子と市場機会の分析、法規制環境、市場規模の推移・予測、各種区分・地域別の詳細分析、特許動向、競合環境、主要企業のプロファイルなどをまとめています。

目次

第1章 イントロダクション

第2章 サマリー・ハイライト

第3章 市場と技術の背景

• 再生医療の概要
• 再生医療はどのように機能するか?
• 再生医療の主なアプローチ
• 細胞と組織
• 組織工学
• 組織工学におけるスキャフォールディングの重要性
• プラスチックススキャフォールディング
• 血管スキャフォールディング
• CIMIT (Center for Integration of Medicine and Innovative Technology)
• 胚性幹細胞

第4章 市場における新興/今後の技術

• 骨・関節再生医療における最新技術の応用
• 整形外科におけるナノマテリアルと再生医療
• 幹細胞とナノメートル技術を用いた再生医療
• ナノ構造軟骨組織工学
• 骨組織工学
• 腱組織工学
• 脂肪組織
• 多血小板血漿（PRP）
• 多細胞/多物質組織の構築のためのバイオプリンティング技術
• 組織工学におけるスキャフォールディングオプション
• ヒドロゲルスキャフォールド
• 固体スキャフォールド
• 将来の機会

第5章 市場力学

• 市場促進要因
• 市場抑制要因
• 市場機会
• COVID-19の影響分析

第6章 市場内訳：技術別

• 世界市場：技術別
• 生体材料
• 再生用生体材料
• 市場規模・予測
• 組織工学
• 市場規模・予測
• 幹細胞療法
• 市場規模・予測

第7章 市場内訳：用途別

• 世界市場：用途別
• 同種骨
• 市場規模・予測
• 自家骨
• 市場規模・予測
• 骨移植片代替品
• 市場規模・予測
• 骨関節疾患
• 市場規模・予測
• その他の病気
• 市場規模・予測

第8章 市場内訳：地域別

• 世界市場：地域別
• 北米
• 米国
• カナダ
• 欧州
• ドイツ
• フランス
• 英国
• イタリア
• ロシア
• スペイン
• その他の欧州
• アジア太平洋
• 中国
• 日本
• オーストラリア
• インド
• その他のアジア太平洋
• その他の地域
• 市場規模・予測

第9章 規制環境

• 骨・関節再生医療の新規承認と承認の加速

第10章 特許レビュー・新たな開発

第11章 競合情勢

• M&A・契約
• 製品の発売
• 製造業者・市場シェア分析

第12章 企業プロファイル

• ANIKA THERAPEUTICS INC.
• ARTHREX INC.
• BAXTER INTERNATIONAL INC.
• BIOVENTUS
• CONMED CORP.
• DEPUY SYNTHES PRODUCTS INC.
• MEDTRONIC PLC
• ROYAL BIOLOGICS
• SEIKAGAKU CORP.
• SMITH & NEPHEW PLC
• STRYKER CORP.
• ZIMMER BIOMET HOLDINGS INC.

第13章 付録：頭字語のリスト

List of Tables

• Summary Table B : Global Market for Regenerative Medicine in Bone and Joint Applications, by Region, Through 2028
• Summary Table A : Global Market for Regenerative Medicine in Bone and Joint Applications, by Technology, Through 2028

Table A : Newly Added Chapters

• Table 1 : List of Developed Organoids from Various Body Organs
• Table 2 : Cumulative Number of Hip and Knee Procedures Performed, 2012-2021
• Table 3 : Global Market for Regenerative Medicine in Bone and Joint Applications, by Technology, Through 2028
• Table 4 : Biomaterial-Assisted Gene Therapy in Musculoskeletal Research
• Table 5 : Global Market for Biomaterials in Bone and Joint Applications, by Region, Through 2028
• Table 6 : Biomaterials Utilized for Specific Target Tissues and Cell Types
• Table 7 : Global Market for Tissue Engineering in Bone and Joint Applications, by Region, Through 2028
• Table 8 : Global Market for Stem Cell Therapy in Bone and Joint Applications, by Region, Through 2028
• Table 9 : Global Market for Regenerative Medicine in Bone and Joint Applications, by Application Type, Through 2028
• Table 10 : Global Market for Regenerative Medicine in Allogeneic Bones Grafting Applications, by Region, Through 2028
• Table 11 : Global Market for Regenerative Medicine in Autogenic Bones Grafting Applications, by Region, Through 2028
• Table 12 : Global Market for Regenerative Medicine in Bone Graft Substitutes Applications, by Region, Through 2028
• Table 13 : Global Market for Regenerative Medicine in Osteoarticular Disease Applications, by Region, Through 2028
• Table 14 : Global Market for Regenerative Medicine in Other Diseases Applications, by Region, Through 2028
• Table 15 : Global Market for Regenerative Medicine in Bone and Joint Applications, by Region, Through 2028
• Table 16 : North American Market for Regenerative Medicine in Bone and Joint Applications, by Technology, Through 2028
• Table 17 : North American Market for Regenerative Medicine in Bone and Joint Applications, by Country, Through 2028
• Table 18 : European Market for Regenerative Medicine in Bone and Joint Applications, by Technology, Through 2028
• Table 19 : European Market for Regenerative Medicine in Bone and Joint Applications, by Country, Through 2028
• Table 20 : Asia-Pacific Market for Regenerative Medicine in Bone and Joint Applications, by Technology, Through 2028
• Table 21 : Asia-Pacific Market for Regenerative Medicine in Bone and Joint Applications, by Country, Through 2028
• Table 22 : RoW Market for Regenerative Medicine in Bone and Joint Applications, by Technology, Through 2028
• Table 23 : New and Accelerated Approvals of Regenerative Medicine for Bones and Joint Applications, 2018-2023
• Table 24 : Patents Registered/Approved on Regenerative Medicine in Bone and Joint Applications, by Assignee Country, 2020-March 2023
• Table 25 : Patents Granted on Regenerative Medicine in Bone and Joint Applications, by Year, 2020-March 2023
• Table 26 : Major Patents on Regenerative Medicine in Bone and Joint Applications, 2022-March 2023
• Table 27 : Recent Mergers, Acquisitions, and Agreements in the Global Regenerative Medicine Market, 2018-2023
• Table 28 : Recently Launched Products, Global Regenerative Medicine Market, 2018-2023
• Table 29 : Anika Therapeutics: R&D Expenditures, 2020-2022
• Table 30 : Anika Therapeutics: Products Offered
• Table 31 : Anika Therapeutics: Recent Developments, 2019-2023
• Table 32 : Arthrex Inc.: Products Offered
• Table 33 : Arthrex Inc.: Recent Developments, 2020-2023
• Table 34 : Boxer International: R&D Expenditures, 2020-2022
• Table 35 : Baxter International: Products Offered
• Table 36 : Baxter International: Recent Developments, 2020-2023
• Table 37 : Bioventus: R&D Expenditures, 2020-2022
• Table 38 : Bioventus: Products Offered
• Table 39 : Bioventus: Recent Developments, 2019-2022
• Table 40 : CONMED Corp.: R&D Expenditures, 2020-2022
• Table 41 : CONMED Corp.: Products Offered
• Table 42 : CONMED Corp.: Recent Developments, 2022
• Table 43 : Johnson & Johnson (DePuy Synthes Companies, MedTech): R&D Expenditures, 2020-2022
• Table 44 : Johnson & Johnson (DePuy Synthes Companies): Products Offered
• Table 45 : Johnson & Johnson (DePuy Synthes Companies): Recent Developments, 2017-2022
• Table 46 : Medtronic plc: R&D Expenditures, 2020-2022
• Table 47 : Medtronic plc: Products Offered
• Table 48 : Medtronic plc: Recent Developments, 2018-2019
• Table 49 : Royal Biologics: Products Offered
• Table 50 : Royal Biologics: Recent Developments, 2020-2022
• Table 51 : Seikagaku Corp.: R&D Expenditures, 2020-2022
• Table 52 : Seikagaku Corp.: Products Offered
• Table 53 : Seikagaku Corp.: Recent Developments, 2019-2021
• Table 54 : Smith & Nephew plc: R&D Expenditures, 2020-2022
• Table 55 : Smith & Nephew plc: Products Offered
• Table 56 : Smith & Nephew plc: Recent Developments, 2019-2022
• Table 57 : Stryker Corp.: R&D Expenditures, 2020-2022
• Table 58 : Stryker Corp.: Products Offered
• Table 59 : Stryker Corp.: Recent Developments, 2020-2022
• Table 60 : Zimmer Biomet Holdings: R&D Expenditures, 2020-2022
• Table 61 : Zimmer Biomet Holdings: Products Offered
• Table 62 : Zimmer Biomet Holdings: Recent Developments, 2022-2023
• Table 63 : Acronyms Used in This Report

List of Figures

• Summary Figure A : Global Market Shares of Regenerative Medicine in Bone and Joint Applications, by Technology, 2022
• Summary Figure B : Global Market for Regenerative Medicine in Bone and Joint Applications, by Region, 2020-2028
• Figure 1 : Emerging Technologies in Regenerative Medicines for Bones and Joint Applications
• Figure 2 : Shares of Platelet-Rich Plasma (PRP) Trials, by Segment, Feb. 2022-Feb. 2023
• Figure 3 : Shares of the Global Health Expenditure Database, by Select Country, 2022
• Figure 4 : Global Aging (65 and Over) Population, by Region, 2019 and 2050
• Figure 5 : Global Market for Regenerative Medicine in Bone and Joint Applications, by Technology, 2020-2028
• Figure 6 : Global Market Shares of Regenerative Medicine in Bone and Joint Applications, by Technology, 2022
• Figure 7 : Global Market for Regenerative Medicine for Biomaterials in Bone and Joint Applications, 2020-2028
• Figure 8 : Global Market for Biomaterials in Bone and Joint Applications, by Region, 2020-2028
• Figure 9 : Global Market for Tissue Engineering in Bone and Joint Applications, 2020-2028
• Figure 10 : Global Market for Tissue Engineering in Bone and Joint Applications, by Region, 2020-2028
• Figure 11 : Global Market for Stem Cell Therapy in Bone and Joint Applications, 2020-2028
• Figure 12 : Global Market for Stem Cell Therapy in Bone and Joint Applications, by Region, 2020-2028
• Figure 13 : Global Market Shares of Regenerative Medicine in Bone and Joint Applications, by Type, 2022
• Figure 14 : Global Market for Regenerative Medicine in Allogeneic Bones Grafting Applications, 2020-2028
• Figure 15 : Global Market for Regenerative Medicine in Allogeneic Bones Grafting Applications, by Region, 2020-2028
• Figure 16 : Global Market for Regenerative Medicine in Autogenic Bones Grafting Applications, 2020-2028
• Figure 17 : Global Market for Regenerative Medicine in Autogenic Bones Grafting Applications, by Region, 2020-2028
• Figure 18 : Global Market for Regenerative Medicine in Bone Graft Substitutes Applications, 2020-2028
• Figure 19 : Global Market for Regenerative Medicine in Bone Graft Substitutes Applications, by Region, 2020-2028
• Figure 20 : Global Market for Regenerative Medicine in Osteoarticular Disease Applications, 2020-2028
• Figure 21 : Global Market for Regenerative Medicine in Osteoarticular Disease Applications, by Region, 2020-2028
• Figure 22 : Global Market for Regenerative Medicine in Other Diseases Applications, 2020-2028
• Figure 23 : Global Market for Regenerative Medicine in Other Diseases Applications, by Region, 2020-2028
• Figure 24 : Global Market for Regenerative Medicine in Bone and Joint Applications, by Region, 2020-2028
• Figure 25 : Global Market Shares of Regenerative Medicine in Bone and Joint Applications, by Region, 2022
• Figure 26 : North American Market Shares of Regenerative Medicine in Bone and Joint Applications, by Technology, 2022
• Figure 27 : North American Market Shares of Regenerative Medicine in Bone and Joint Applications, by Country, 2022
• Figure 28 : U.S. Market for Regenerative Medicine in Bone and Joint Applications, 2020-2028
• Figure 29 : Canadian Market for Regenerative Medicine in Bone and Joint Applications, 2020-2028
• Figure 30 : European Market Shares of Regenerative Medicine in Bone and Joint Applications, by Technology, 2022
• Figure 31 : European Market Shares of Regenerative Medicine in Bone and Joint Applications, by Country, 2022
• Figure 32 : German Market for Regenerative Medicine in Bone and Joint Applications, 2020-2028
• Figure 33 : French Market for Regenerative Medicine in Bone and Joint Applications, 2020-2028
• Figure 34 : U.K. Market for Regenerative Medicine in Bone and Joint Applications, 2020-2028
• Figure 35 : Italian Market for Regenerative Medicine in Bone and Joint Applications, 2020-2028
• Figure 36 : Russian Market for Regenerative Medicine in Bone and Joint Applications, 2020-2028
• Figure 37 : Spanish Market for Regenerative Medicine in Bone and Joint Applications, 2020-2028
• Figure 38 : Rest of European Market for Regenerative Medicine in Bone and Joint Applications, 2020-2028
• Figure 39 : Asia-Pacific Market Shares of Regenerative Medicine in Bone and Joint Applications, by Technology, 2022
• Figure 40 : Asia-Pacific Market Shares of Regenerative Medicine in Bone and Joint Applications, by Country, 2022
• Figure 41 : Chinese Market for Regenerative Medicine in Bone and Joint Applications, 2020-2028
• Figure 42 : Japanese Market for Regenerative Medicine in Bone and Joint Applications, 2020-2028
• Figure 43 : Australian Market for Regenerative Medicine in Bone and Joint Applications, 2020-2028
• Figure 44 : Indian Market for Regenerative Medicine in Bone and Joint Applications, 2020-2028
• Figure 45 : Rest of Asia-Pacific Market for Regenerative Medicine in Bone and Joint Applications, 2020-2028
• Figure 46 : RoW Market Shares of Regenerative Medicine in Bone and Joint Applications, by Technology, 2022
• Figure 47 : Shares of Patents Registered/Approved on Regenerative Medicine in Bone and Joint Applications, by Assignee Country, 2020-March 2023
• Figure 48 : Global Market Shares Regenerative Medicine in Bone and Joint Applications, by Key Players, 2022
• Figure 49 : Anika Therapeutics: Net Revenue, 2018-2022
• Figure 50 : Anika Therapeutics: Revenue Share, by Business Segment, 2022
• Figure 51 : Anika Therapeutics: Revenue Share, by Region/Country, 2022
• Figure 52 : Baxter International: Net Revenue, 2018-2022
• Figure 53 : Baxter International: Revenue Share, by Business Segment, 2022
• Figure 54 : Baxter International: Revenue Share, by Region, 2022
• Figure 55 : Bioventus: Net Revenue, 2018-2022
• Figure 56 : Bioventus: Revenue Share, by Business Segment, 2022
• Figure 57 : Bioventus: Revenue Share, by Region, 2022
• Figure 58 : CONMED Corp.: Net Revenue, 2018-2022
• Figure 59 : CONMED Corp.: Revenue Share, by Business Segment, 2022
• Figure 60 : CONMED Corp.: Revenue Share, by Region, 2022
• Figure 61 : Johnson & Johnson (DePuy Synthes Companies): Net Revenue, 2018-2022
• Figure 62 : Johnson & Johnson (DePuy Synthes): Revenue Share, by Business Segment, 2022
• Figure 63 : Johnson & Johnson (DePuy Synthes Companies): Revenue Share, by Region, 2022
• Figure 64 : Medtronic plc: Net Revenue, 2018-2022
• Figure 65 : Medtronic plc: Revenue Share, by Business Segment, 2022
• Figure 66 : Medtronic plc: Revenue Share, by Region, 2022
• Figure 67 : Seikagaku Corp.: Net Revenue, 2018-2022
• Figure 68 : Seikagaku Corp.: Revenue Share, by Business Segment, 2022
• Figure 69 : Smith & Nephew plc: Net Revenue, 2018-2022
• Figure 70 : Smith & Nephew plc: Revenue Share, by Business Segment, 2022
• Figure 71 : Smith & Nephew plc: Revenue Share, by Region, 2022
• Figure 72 : Stryker Corp.: Net Revenue, 2018-2022
• Figure 73 : Stryker Corp.: Revenue Share, by Business Segment, 2022
• Figure 74 : Stryker Corp.: Revenue Share, by Region, 2022
• Figure 75 : Zimmer Biomet Holdings: Net Revenue, 2018-2022
• Figure 76 : Zimmer Biomet Holdings: Revenue Share, by Business Segment, 2022
• Figure 77 : Zimmer Biomet Holdings: Revenue Share, by Region, 2022

Highlights:

The global market for regenerative medicine in bone and joint applications reached $9.6 billion in 2022. The market is estimated to increase from $10.7 billion in 2023 to $18.9 billion by 2028, at a compound annual growth rate (CAGR) of 12.1% from 2023 through 2028.

The biomaterials technology segment in the global market for regenerative medicine in bone and joint applications is estimated to increase from $6.4 billion in 2023 to $11.03 billion by 2028, at a CAGR of 11.3% from 2023 through 2028.

The tissue engineering segment in the global market for regenerative medicine in bone and joint applications is estimated to increase from $2.7 billion in 2023 to $5.04 billion by 2028, at a CAGR of 13.3% from 2023 through 2028.

Report Scope:

The report explains critical trends in the regenerative medicine industry. It discusses the market determinants, which act as motivating or restraining factors, and provides insights to stakeholders and potential entrants.

This study looks at most of the systems affected by factors such as R&D spending and increasing competition and new technologies.

This report also covers merger and acquisition strategies and collaborations, as well as the strengths and weaknesses of each strategy type.

The market has also been analyzed based on regenerative medicine for bone and joint applications. Categories considered in this report include allogeneic bones, autogenic bones, bone graft substitutes, osteoarticular diseases, and others.

The report provides information to all market players, potential entrants, government agencies, and other interested parties. As the report covers geographic regions in detail, companies interested in expanding their geographic reach will also find this study useful.

Report Includes:

• 36 data tables and 30 additional tables
• An up-to-date review and in-depth assessment of the global markets for regenerative medicine in bone and joint applications
• Analyses of the global market trends, with historical market revenue data (sales figures) for 2020-2022, estimates for 2023, and projections of compound annual growth rates (CAGRs) through 2028
• Estimation of the actual market size and revenue forecast for regenerative medicine for bone and joint applications market, and corresponding market share analysis based on the type of technology, application, and region
• Highlights of the importance of biomaterials, stem cell therapy, tissue engineering, and emerging/upcoming technologies (including bioprinting) in the regenerative medicine industry, along with the long-term impacts of regenerative medicine technologies, both existing and in developmental stage
• Country specific data analysis and market growth forecasts for the U.S., Canada, Germany, the UK, France, Italy, Russia, Spain, Australia, Japan, China and India
• Discussion of major growth drivers and restraints, technology advancements, product innovations and regulatory aspects that will shape the market for regenerative medicine for bone and joint applications as a basis for projecting demand in the next few years (2023-2028)
• Identification of the companies best positioned to meet this demand owing to or in conjunction with their proprietary technologies, product launches, and other strategic advantages
• Holistic review of the impact of COVID-19 and other economic and demographic factors affecting the market growth in the analysis period
• A relevant patent analysis with the number of patents registered/approved, ongoing industry clinical trials, and recent mergers, acquisitions, and collaboration agreements in the regenerative medicine industry
• Insight into the recent industry structure, competitive aspects of each product segments, increasing investment on global R&D activities, market growth strategies, and company revenue share analysis
• Identification of leading and emerging competitors in the global regenerative medicine market, and analysis of competitive landscape based on recent developments and segmental revenues
• Company profiles descriptions of the major market players, including Smith & Nephew Plc, DePuy Synthes, Medtronic plc, Stryker Corp., Bioventus, Zimmer Biomet, Anika Therapeutics, Baxter Intl., and CONMED Corp.

Table of Contents

Chapter 1 Introduction

• Background
• Study Goals and Objectives
• Reasons for Doing This Study
• What's New in This Update?
• Scope of Report
• Information Sources
• Research Methodology
• Geographic Breakdown
• Analyst's Credentials
• BCC Custom Research
• Related BCC Research Reports

Chapter 2 Summary and Highlights

Chapter 3 Market and Technology Background

• Overview of Regenerative Medicine
• How Regenerative Medicine Works?
• Principal Approaches to Regenerative Medicine
• Cells and Tissues
• Tissue Engineering
• Importance of Scaffolding in Tissue Engineering
• Plastic Scaffolding
• Blood Vessel Scaffolding
• Center for Integration of Medicine and Innovative Technology (CIMIT)
• Embryonic Stem Cells

Chapter 4 Emerging/Upcoming Technologies in the Market

• Emerging Technologies in Regenerative Medicines for Bones and Joint Applications
• Nanomaterials and Regenerative Medicine in Orthopedic Surgery
• Regeneration Therapy Using Stem Cells and Nanometer Technology
• Nanostructured Cartilage Tissue Engineering
• Bone Tissue Engineering
• Tendon Tissue Engineering
• Adipose Tissue
• Platelet-Rich-Plasma (PRP)
• Bioprinting Technologies for Construction of Multicellular/Multi-material Tissues
• Scaffolding Option in Tissue Engineering
• Hydrogel Scaffold
• Solid Scaffold
• Future Opportunities

Chapter 5 Market Dynamics

• Market Drivers
• Growing Number of Bone and Joint Disorders and Orthopedic Surgeries
• Increasing Expenditures for Health Care and Investments in Regenerative Medicines
• Increasing Geriatric Population
• Increasing Product Approvals and Launches
• R&D for Stem and Gene Therapies
• Market Restraints
• Stringent Government Regulatory Settings in R&D
• Market Opportunities
• Growing Pipeline for Regenerative Medicines
• COVID-19 Impact Analysis
• Impact of COVID-19 on the Market for Cell and Gene Therapies and Regenerative Medicine for Bone and Joint Applications
• Direct Impact on Clinical Trials in Cell and Gene Therapy
• Post-COVID-19 Effect on Regenerative Medicine for Bones and Joint Applications

Chapter 6 Market Breakdown by Technology

• Global Market, by Technology
• Biomaterials
• Biomaterials for Regeneration
• Market Size and Forecast
• Tissue Engineering
• Market Size and Forecast
• Stem Cell Therapy
• Market Size and Forecast

Chapter 7 Market Breakdown by Application

• Global Market, by Application
• Allogeneic Bones
• Market Size and Forecast
• Autogenic Bones
• Market Size and Forecast
• Bone Graft Substitutes
• Market Size and Forecast
• Osteoarticular Diseases
• Market Size and Forecast
• Other Diseases
• Market Size and Forecast

Chapter 8 Market Breakdown by Region

• Global Market, by Region
• North America
• United States
• Canada
• Europe
• Germany
• France
• United Kingdom
• Italy
• Russia
• Spain
• Rest of Europe
• Asia-Pacific
• China
• Japan
• Australia
• India
• Rest of Asia-Pacific
• Rest of the World
• Market Size and Forecast

Chapter 9 Regulatory Aspects

• New and Accelerated Approvals of Regenerative Medicine for Bones and Joint Applications

Chapter 10 Patent Review/New Developments

• Patent Analysis, by Year

Chapter 11 Competitive Landscape

• Mergers, Acquisitions, and Agreements
• Product Launches
• Manufacturers of Regenerative Medicine for Bones and Joint Applications and their Market Share Analysis

Chapter 12 Company Profiles

• ANIKA THERAPEUTICS INC.
• ARTHREX INC.
• BAXTER INTERNATIONAL INC.
• BIOVENTUS
• CONMED CORP.
• DEPUY SYNTHES PRODUCTS INC. (PART OF JOHNSON & JOHNSON)
• MEDTRONIC PLC
• ROYAL BIOLOGICS
• SEIKAGAKU CORP.
• SMITH & NEPHEW PLC
• STRYKER CORP.
• ZIMMER BIOMET HOLDINGS INC.

Chapter 13 Appendix: List of Acronyms