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動物生産における抗生物質

Animal Pharm Antibiotics in Animal Production 2016

発行 Animal Pharm 商品コード 397895
出版日 ページ情報 英文 65 Pages
納期: 即日から翌営業日
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動物生産における抗生物質 Animal Pharm Antibiotics in Animal Production 2016
出版日: 2016年10月30日 ページ情報: 英文 65 Pages
概要

当レポートでは、動物生産における抗生物質市場について調査し、動物用抗生物質の市場規模、動物における抗生物質の非治療用途 (抗生物質成長促進剤) 、抗生物質耐性に対する法律・消費者の反応、および動物生産における抗生物質成長促進剤 (AGP) に代わる戦略などについて、まとめています。

エグゼクティブサマリー

第1章 イントロダクション

第2章 抗生物質の治療用途

  • 人間の治療
  • 動物の治療
  • 動物用抗生物質の市場規模

第3章 動物における抗生物質の非治療用途

  • 抗生物質成長促進剤 (AGP) の作用機序

第4章 抗生物質耐性

  • 抗生物質体制の生化学的基礎

第5章 抗生物質耐性への対応としての非抗生物質抗菌剤

  • クオラムセンシング・クエンチャー
  • 鉄キレート剤
  • レクチン阻害剤
  • ファージセラピー
  • フィトケミカル (植物発生、植物学)
  • 抗微生物ペプチド
  • プロバイオティクス
  • ワクチン

第6章 抗生物質耐性に対する法律・消費者の反応

  • 法的対応
    • ベルギー
    • デンマーク
    • フランス
    • ドイツ
    • オランダ
    • スウェーデン
    • 英国
  • 消費者の反応

第7章 動物生産における抗生物質成長促進剤 (AGP) に代わる戦略

  • 飼料用酵素
  • 有機酸
  • フィトケミカル
  • プレバイオティクス
  • プロバイオティクス

第8章 動物の健康・成長の抗生物質不使用管理

  • ブロイラー
  • 豚の生産
  • 乳牛

第9章 結論

第10章 参考資料

付録

目次
Product Code: 85873

Antibiotics are probably one of the most successful forms of chemotherapy in the history of medicine. They are not only of great therapeutic value in human disease control but are equally effective in animals raised for food and in domestic pets.

Antibiotics are used in animal production as therapeutic agents to cure and control disease and also as non-therapeutic agents or as antibiotic growth promoters (AGPs). The application of AGPs was discovered very soon after the introduction of antibiotics and so both applications have been widely used over the last 70 years.

However, the use of AGPs has elicited substantial controversy in relation to the development of antibiotic resistance in pathogenic bacteria. This has led to the emergence of 'superbugs' such as Methicillin-resistant Staphylococcus aureus (MRSA) and extremely drug-resistant tuberculosis, bacteria which are difficult to treat with existing medicines.

There is now an enormous amount of evidence that use of antibiotics in animal production has contributed to the development of antibiotic resistance and this has serious implications for public health.

One response to the problem of antibiotic resistance is to develop non-antibiotic antimicrobial agents. Consequently, there is considerable research is being carried out to develop non-antibiotic therapeutics, using quorum sensing quenchers, iron chelators, lectin inhibitors, phage therapy, phytochemicals, antimicrobial peptides, probiotics, and vaccines.

The issue of antibiotic resistance has elicited both a legislative and a consumer response. This was manifested by the EU banning all AGPs in 2006. Several member states of the EU have set up programmes designed to reduce the amounts of antibiotics used in animal production. Consumer pressure has encouraged many major meat producing companies to reduce and even eliminate antibiotic use in animal production.

Various strategies have been developed to replace AGPs in animal production although it appears that the economic consequences of the banning of AGPs in the EU have been relatively minor for the poultry industry. There has been an increased focus on the use of various feed additives such as feed enzymes, organic acids, phytochemicals, prebiotics and probiotics.

Another response to concerns about antibiotics in animal production is to develop antibiotic-free systems. This focuses on disease avoidance and health maintenance rather than using therapeutic treatments. Significant progress has been made in reducing and even eliminating antibiotics from dairy cows, pigs and poultry.

Table of Contents

  • Contents
  • About the Author
  • Disclaimer

EXECUTIVE SUMMARY

1. INTRODUCTION

2. THERAPEUTIC USE OF ANTIBIOTICS

  • 2.1. Treatment of Humans
  • 2.2. Treatment of Animals
  • 2.3. Market Size of Antibiotics used in Animals

3. NON-THERAPEUTIC USE OF ANTIBIOTICS IN ANIMALS

  • 3.1. Mode of Action of AGPs

4. ANTIBIOTIC RESISTANCE

  • 4.1. Biochemical basis of Antibiotic Resistance

5. NON-ANTIBIOTIC ANTIMICROBIAL AGENTS AS A RESPONSE TO ANTIBIOTIC RESISTANCE

  • 5.1. Quorum Sensing and Quenchers
  • 5.2. Iron Chelators
  • 5.3. Lectin Inhibitors
  • 5.4. Phage Therapy
  • 5.5. Phytochemicals (Phytogenics, Botanicals)
  • 5.6. Antimicrobial Peptides
  • 5.7. Probiotics
    • 5.7.1. Bacteriocins
  • 5.8. Vaccines
    • 5.8.1. Plant-based edible vaccines

6. LEGISLATIVE AND CONSUMER RESPONSES TO ANTIBIOTIC RESISTANCE

  • 6.1. Legislative Responses
  • 6.1.1. Belgium
  • 6.1.2. Denmark
  • 6.1.3. France
  • 6.1.4. Germany
  • 6.1.5. Netherlands
  • 6.1.6. Sweden
  • 6.1.7. United Kingdom
  • 6.2. Consumer Responses

7. STRATEGIES TO REPLACE ANTIBIOTIC GROWTH PROMOTERS IN ANIMAL PRODUCTION

  • 7.1. Feed Enzymes
  • 7.2. Organic Acids
  • 7.3. Phyochemicals
  • 7.4. Prebiotics
  • 7.5. Probiotics

8. ANTIBIOTIC-FREE MANAGEMENT OF ANIMAL HEALTH AND GROWTH

  • 8.1. Broilers
    • 8.1.1. Prebiotics
    • 8.1.2. Probiotics
  • 8.2. Pig Production
  • 8.3. Dairy Cows

9. CONCLUSIONS

10. REFERENCES

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