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市場調査レポート

糖尿病:ハーブ生物活性分子vs.医薬品 - シナモンの世界市場・競合企業・機会 - 分析と予測

DIABETES: HERBAL BIOACTIVE MOLECULES VS. PHARMACEUTICAL DRUGS - VOLUME 1: CINNAMON GLOBAL MARKETS, COMPETITORS AND OPPORTUNITIES - 2014-2019 ANALYSIS AND FORECASTS

発行 Amadee & Company, Inc. 商品コード 297163
出版日 ページ情報 英文 328 Pages
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糖尿病:ハーブ生物活性分子vs.医薬品 - シナモンの世界市場・競合企業・機会 - 分析と予測 DIABETES: HERBAL BIOACTIVE MOLECULES VS. PHARMACEUTICAL DRUGS - VOLUME 1: CINNAMON GLOBAL MARKETS, COMPETITORS AND OPPORTUNITIES - 2014-2019 ANALYSIS AND FORECASTS
出版日: 2014年03月06日 ページ情報: 英文 328 Pages
概要

2013年における糖尿病患者数は3億8200万人、世界人口の8.3%となりました。2035年までにこの数字は6億人となり、世界人口の10.1%に匹敵する見込みです。糖尿病は経済的に大きな影響を持っています。例えば米国では、2012年における直接医療コストの1,760億米ドルを含めた糖尿病診断コストが、2,450億米ドルと推計されています。2013年の米国における1人あたりの糖尿病関連支出は9,800米ドルでした。同年の世界における1人当たりの糖尿病関連支出は1436米ドルでした。さらに、世界の糖尿病薬物療法市場は2013年に450億米ドルとなり、年間10.5%で成長しています。インスリンの売上はCAGR14.2%で拡大しています。

当レポートでは、世界の糖尿病市場について包括的に調査し、国別の発生率、種類別の経済的影響、糖尿病管理のための薬草の分析、糖尿病管理におけるシナモンの可能性、生産、輸出入および貿易業者を含めた世界のシナモン市場の分析および主要企業のプロファイルを含め、概略以下の構成でお届けいたします。

エグゼクティブサマリー

イントロダクション

  • 背景
  • 調査方法・情報源
  • 統計に関する注釈

糖尿病市場の概要

  • パンデミック
  • 正統派アプローチ
  • ライフスタイルの変化
  • ダイエット
  • 非正統派アプローチ:薬草
  • 糖尿病の世界的な経済への影響
  • 糖尿病発生率:国別
  • 糖尿病有病率:国別
  • 1人当たりの糖尿病関連支出:国別
  • 米国における糖尿病の経済コスト
  • 米国における糖尿病のコスト:タイプ別
  • 糖尿病薬物療法企業の市場シェア
  • インスリンは最終的ソリューション
  • インスリン市場の成長促進因子
  • インスリン市場の価値促進因子
  • インスリン市場の成長
  • インスリン市場の成長:地域別
  • インスリン市場のセグメント(即効性、プレミックス、長時間作用型)
  • GLP-1

薬草と糖尿病

  • 従来型の治療
  • 従来型の抗糖尿病薬
  • 薬草:糖尿病管理に安全なツール
  • 一般的に利用される薬草における作用機序
  • 薬理学的に検査されたインスリン模倣性のもしくはインスリン分泌促進植物材料およびPhytoconstituent
  • 66植物の血糖降下作用およびバイオ活性成分に関する実証研究

シナモンと糖尿病

  • 定義
  • フレーバー、アロマおよび味
  • 歴史
  • 農学研究・開発の取り組み
  • 栽培
  • グレード付け
  • 処理・加工
  • 利用
  • 副作用
  • 糖尿病管理のためのシナモンの医療潜在性
  • シナモンの生物学的影響
  • シナモンの生物学的効果、ほか

シナモン市場の概要

  • シナモンvs.薬物療法漢方の生産
  • 生産
  • シナモン市場
  • シナモン市場展望
  • シナモン輸出:国別
  • シナモンの貿易収支:国別
  • シナモン市場の輸出入企業

企業プロファイル

付録1:糖尿病の概要

付録2:インスリンの概要

図表

目次

Diabetes is a metabolic disorder arising mainly due to the fault in the production of insulin or mounting resistance to its action. In the case of Diabetes, the most serious problem is the side effect, which occurs due to the accumulation of glucose. This excess glucose is converted into various compounds and also into free radicals, which damage the vital organs and organelles. Diabetes was seriously underrated as a threat to global public health until very recently. Today, Diabetes now ranks as one of the greatest public health challenges in the history of mankind. There were 382 million people with Diabetes, or 8.3% of the global population, in 2013. By 2035, this number will be 10.1%, equal almost 600 million people worldwide.

Diabetes has a very large economic impact. For example, in the US the cost of diagnosed Diabetes in 2012 is estimated at US$245 billion, including $176 billion in direct medical costs. In 2013, the average Diabetes related expenditures per person in the US was USD9,800. Globally, per capita Diabetes related expenditures in 2013 was USD1,436. Further, the global market for Diabetes medications is estimated at approximately USD45 billion in 2013 and is growing 10.5% annually overall, with insulin sales increasing at a 14.2% CAGR.

The currently available antidiabetic drugs manage the blood glucose levels under normal range by supplementing insulin, improving insulin sensitivity, increasing insulin secretion from the pancreas, decreasing glucose absorption from the intestinal tract and/or glucose uptake by tissue cells.

Today, the management of Diabetes without any side effect is still a challenge to the medical fraternity. However, a wide array of plant-derived active principles has demonstrated antidiabetic activity. These natural medicines modulate blood sugar levels through a variety of mechanisms. In some cases their effects are similar to conventional medicines.

This report looks at the use of medicinal plants, rather than pharmaceutical drugs, to both prevent and treat Diabetes. Specifically, it looks in detail at one of these plants: Cinnamon. Cinnamon is widely used and available and the market for it is well developed. The modern literature indicates that the potential antidiabetic properties of Cinnamon have been studied for over 20 years. Numerous trials have been conducted in humans to determine the metabolic effects of Cinnamon.

This report provides:

  • A detailed look at the Diabetes market including its incidence by country now and during the next 20 years, economic impacts and costs by type, especially medications.
  • Analysis of medicinal plants to manage Diabetes including experimental studies on the hypoglycaemic activity and bioactive components of 66 plants.
  • The potential of Cinnamon for the management of Diabetes including its biological effects, molecular mechanisms of action and clinical studies.
  • Analysis of the global market for Cinnamon including production, imports, exports and traders.

Additionally, profiles of 45 leading, public and private companies involved in the Cinnamon industry as producers, distributors, and retailers are given. The report also includes 30 tables and 50 figures.

Table of Contents

CONTENTS

EXECUTIVE SUMMARY

INTRODUCTION

  • Background
  • Methodology and Sources
  • Statistical Notes

DIABETES MARKET OVERVIEW

  • Pandemic
  • Orthodox Approach
  • Lifestyle Changes
  • Diet
  • Nonorthodox Approach: Medicinal Plants
  • Global Economic Impact Of Diabetes
  • World Population Of 20-79 Year Olds: 2013-2035
  • Diabetes Incidence By Country
  • Diabetes Prevalence By Country: 2013-2035
  • Diabetes-Related Expenditure Per Person By Country: 2013-2035
  • Economic Costs Of Diabetes In The US
  • US Diabetes Costs By Type
  • Diabetes Medications Company Market Shares
  • Insulin Is The Final Solution
  • Insulin Market Growth Drivers
  • Insulin Market Value Drivers
  • Insulin Market Growth: 2008-2013
  • Insulin Market Growth By Region
  • Insulin Market Segments (Fast Acting, Premix, Long Acting)
  • GLP-1

MEDICINAL PLANTS AND DIABETES

  • Conventional Treatment
  • Conventional Antidiabetic Drugs
  • Medicinal Plants: A Safe Tool To Manage DM
  • Mechanism Of Action In Commonly Used Medicinal Plants
  • Pharmacologically Screened Insulinomimetic Or Insulin Secretagogues Plant Material And Phytoconstituents
  • Experimental Studies On Hypoglycaemic Activity And Bioactive Components Of 66 Plants
  • Acacia arabica
  • Aegle marmelos
  • Agrimony eupatoria
  • Allium sativum
  • Aloe vera
  • Annona muricata
  • Annona squamosa
  • Asparagus racemosus
  • Bauhinia variegata
  • Berberine
  • Biophytum sensitivum
  • Boerhaavia diffusa
  • Bougainvillea spectabilis
  • Brassica nigra
  • Caesalpinia bonducella
  • Caffeine
  • Camellia sinensis
  • Capsicum frutescens
  • Catharanthus roseus
  • Cinnamon zeylaniucm
  • Citrullus colocynthis
  • Coccinia indica
  • Cornus officinalis
  • Elephantopus scaber
  • Enicostemma littorale
  • Ephedra distachya
  • Eriobotrya japonica
  • Euccalyptus globulus
  • Eugenia jambolana
  • Ficus bengalensis
  • Fermented Unsalted Soybeans
  • Genistein
  • Ginkgo biloba
  • Radix glycyrrhizae
  • Gymnema sylvestre
  • Helicteres isora
  • Hibiscus rosa sinensis
  • Hordeum vulgare
  • Lepechinia caulescens
  • Medicago sativa
  • Momordica charantia
  • Mucuna pruriens
  • Nigella sativa oil
  • Panax ginseng
  • Pandanus odorus
  • Parinari excelsa
  • Prunella vulgaris
  • Psidium guajava
  • Pterocarpus marsupium
  • Radix rehmanniae
  • Rehmania glutinosa
  • Ricinus communis
  • Syzygium cumini
  • Salvia lavandifolia
  • Sarcopoterium spinosum
  • Selaginella tamariscina
  • Semen coicis
  • Smallanthus sonchifolius
  • Stevia rebaudiana
  • Swertia chirayita
  • Swertia punicea
  • Tabernanthe iboga
  • Teucrium polium
  • Tinospora crispa
  • Tribuluks terrestris
  • Trigonella foenum-graecum
  • Zizyphus spina-christi
  • Conclusions
  • Medicinal Plant Market
  • Production
  • Exports
  • Imports
  • Trade Balance

CINNAMON AND DIABETES

  • Definition
  • Genus Cinnamomum
  • Species
  • Flavor, Aroma And Taste
  • History
  • Early History
  • Modern History
  • Agronomy Research And Development Efforts
  • Cultivation
  • Grading
  • Processing
  • Uses
  • Adverse Effects
  • Clinical Potential Of Cinnamon For The Management Of Diabetes
  • Biological Effects Of Cinnamon
  • Cinnamon Has Been Studied For Over 20 Years
  • Molecular Mechanisms Of Action Of Cinnamon
  • Clinical Studies With Cinnamon
  • Conclusions

CINNAMON MARKET OVERVIEW

  • Cinnamon Vs. Medicinal Plant Production
  • Production
  • Cinnamon Market: 1992-2013
  • Cinnamon Market Outlook: 2014-2019
  • Cinnamon Exports By Country
  • Cinnamon Trade Balance By Country
  • Cinnamon Export And Import Companies

COMPANY PROFILES

  • A.A. Sayia & Company, Inc
  • A. Baur & Co (Pvt.) Ltd.
  • ACH Food Companies, Inc.
  • Adam Group
  • Adams Extract & Spice, LLC
  • Ajinomoto Co., Inc.
  • Bart Ingredients Company Ltd
  • Bio Foods Pvt Ltd
  • Bolner's Fiesta Products
  • Ceylon Spice Company
  • C.F. Sauer Company
  • EOAS International
  • Everson Spice Company
  • First Spice Mixing Company
  • Frontier Natural Products Co-op Inc.
  • Goya Foods, Inc.
  • HDDES Group
  • Hong Son Cassia & Star Aniseed Processing Co., Ltd.
  • Horn Company
  • Huong Que Company
  • Indus Organics
  • Integrity Nutraceuticals International Founded
  • Intercom Limited
  • Ishana Spice Exports
  • L B Spices Trading (Private) Limited
  • La Flor Spices
  • La India Packing Company
  • McCormick & Company, Incorporated
  • Monteray Bay Spice Company
  • Mountain Rose Herbs
  • Nature's Agro Products Lanka Company
  • Novo Nordisk A/S
  • Olam International Limited
  • Orient Vietnam Company Limited
  • PT Cassia Co-Op
  • PT Dwiwarna Inti Sejahtera
  • Rathna Producers Cinnamon Exports (Pvt) Ltd.
  • Saboor Chatoor (Private) Limited
  • SC Seasoning Co., Inc.
  • SDS Spices (PVT) Ltd.
  • Spice House USA
  • The Empire Associates
  • Tripper
  • Vanns Spices
  • Whole Foods Market, Inc.
  • Wixon Inc.

APPENDIX 1: DIABETES OVERVIEW

  • Classification
  • Insulin
  • Untreated Diabetes
  • Treated Diabetes
  • Poor Diagnosis Rates
  • Type 2 Medications
  • History
  • Type 1 Diabetes
  • Cause
  • Genetics
  • Environmental
  • Diet
  • Chemicals And Drugs
  • Pathophysiology
  • Diagnosis
  • Tight Glycaemic Control
  • Autoantibodies
  • Prevention
  • Immunosuppressive Drugs
  • Management
  • Pancreas Transplantation
  • Islet Cell Transplantation
  • Stem Cell Educator Therapy
  • Depression
  • Eating Disorders
  • Complications
  • Time Of Diagnosis
  • GAD65 Vaccine
  • T Helper Cell Shift
  • Labile Diabetes
  • Type 2 Diabetes
  • Signs and Symptoms
  • Complications
  • Cause
  • Lifestyle
  • Genetics
  • Medical Conditions
  • Pathophysiology
  • Diagnosis
  • Prevention
  • Management
  • Lifestyle
  • Medications
  • Surgery
  • Metabolic Syndrome
  • History
  • Definitions And Diagnosis
  • IDF
  • WHO
  • EGIR
  • NCEP
  • American Heart Association
  • Other
  • Etiology
  • Pathophysiology
  • Stress
  • Overweight And Obesity
  • Sedentary Lifestyle
  • Aging
  • Type 2 Risk
  • Coronary Heart Disease
  • Lipodystrophy
  • Psychiatric Illnesses
  • Rheumatic Diseases
  • Signs and Symptoms
  • Prevention
  • Therapy
  • Controversy
  • Diabetes And Food Prices

APPENDIX 2: INSULIN OVERVIEW

  • Gene
  • Alleles
  • Regulation
  • Protein Structure
  • Synthesis
  • Release
  • Oscillations
  • Blood Content
  • Signal Transduction
  • Effect On Glucose Uptake and Metabolism
  • Degradation
  • Hypoglycemia
  • Diseases And Syndromes
  • Medication
  • Discovery
  • Extraction And Purification
  • Synthesis
  • Nobel Prizes
  • Glucagon-Like Peptide-1
  • Physiological Functions
  • Leptin
  • Physiology
  • Function
  • Adiposity Signal
  • Interaction With Amylin
  • Metreleptin

TABLES

  • 1. Global Diabetes Market Summary: 2014-2019
  • (Diabetes Cases (Million), Diabetes Related Expenditures Per Person (USD), Total Diabetes Related Expenditures (USD Billion), Total Diabetes Medications Demand (USD Billion), Medicinal Plants Production (USD Billion), Cinnamon Production (USD Million)
  • 2. Population Of 20-79 Year Olds Ranked For The World
  • And 218 Countries Plus Growth Rates: 2013-2035
  • 3. Diabetes Cases (1000s) Among 20-79 Year Olds Ranked For The World And 218 Countries Plus Growth Rates: 2013-2035
  • 4. Diabetes National Prevalence (%) Ranked For The World And 218 Countries: 2013-2035
  • 5. Diabetes-Related Expenditures Per Person With Diabetes For The World And 218 Countries (USD): 2013
  • 6. US Health Care Expenditures By Diabetes Status And Type Of Service (USD Million): 2012
  • 7. US Health Care Expenditures Attributed To Diabetes By Age Group And Type Of Service (USD Million): 2012
  • 8. US Per Capita Health Care Expenditures Attributed To Diabetes By Age Group And Type Of Service (USD Million): 2012
  • 9. US Health Care Expenditures Attributed To Diabetes By Medical Condition And Type Of Service (USD Million): 2012
  • 10. US Annual Per Capita Health Care Expenditures By Diabetes Status (Actual Dollars): 2012
  • 11. Existing Synthetic Drugs For Type 2 DM In Market And Their Molecular Targets, Site Of Action And Adverse Reactions
  • 12. Commonly Used Conventional And Natural Medicines For Diabetes
  • 13. List Of Plants Having Antidiabetic Activity
  • 14. List of Plants Having Insulin Mimetic Or Insulin Secreatory Activity
  • 15. List Of Plants Phytoconstituents Having Insulin Secretagogues Or Insulin Mimetic Activity
  • 16. Global Medicinal Plant Exports By Country And Growth Rate (USD Thousands): 2008-2012
  • 17. Global Medicinal Plant Imports By Country And Growth Rate (USD Thousands): 2008-2012
  • 18. Global Medicinal Plant Trade Balance By Country And Growth Rate (USD Thousands): 2008-2012
  • 19. Summary Of Human Studies Where Patients With Type 2 Diabetes, Metabolic Syndrome, Impaired Fasting Glucose And Associated Diseases Were Treated With Cinnamon
  • 20. Global Medicinal Plant Vs. Cinnamon Production (USD Million): 2014-2019
  • 21. Global Cinnamon Production By Country (Metric Tons): 1982-2012
  • 22. Global Cinnamon Market (USD Million, Metric Tons, Average Selling Price): 1992-2013
  • 23. Global Cinnamon Market (USD Million, Metric Tons, Average Selling Price): 2014-2019
  • 24. Global Exports Of Cinnamon For World And 121 Countries (USD Thousand): 2008-2012
  • 25. Global Imports Of Cinnamon For World And 198 Countries (USD Thousand): 2008-2012
  • 26. Global Trade Balance Of Cinnamon For World And 202 Countries (USD Thousand): 2008-2012
  • 27. 481 Cinnamon Export Companies By Country (Name, Product/Service Categories Traded, Employees, Country, Website): 2014
  • 28. 201 Cinnamon Import Companies By Country (Name, Product/Service Categories Traded, Employees, Country, Website): 2014
  • 29. Comparison Of Type 1 And Type 2 Diabetes
  • 30. Commonly Prescribed Products For The Treatment Of Type 2 Diabetes

FIGURES

  • 1. Global Diabetes Medications Market By Treatment Class (GLP-1, Insulin, OAD): 2003-2013
  • 2. Global Diabetes Medications Market Shares By Company (%): 2003-2013
  • 3. Progression Of Type 2 Diabetes And Treatment Intensification
  • 4. Distribution Of Patients And Value Across Treatment Classes
  • 5. Global Insulin Market Growth By Component: 2008-2013
  • 6. Global Insulin Market: Device Penetration Vs. Modern Insulin Penetration
  • 7. Global Modern Insulin Volume Company Market Shares
  • 8. Insulin Market Size And Growth By Region, Volume Composition, Volume Market Shares By Company: 2012-2013
  • 9. Regional (North America, Europe, China, Japan, Korea) Insulin Market Volume Growth Rates: 2003-2013
  • 10. Regional (North America, Europe, China, Japan, Korea) Insulin Volume Market Split: 2003-2013
  • 11. Action Profiles Of Insulins By Type
  • 12. Global Insulin Market Volume And Growth By Segment: 2008-2013
  • 13. Global GLP-1 Market Value And Market Share: 2008-2013
  • 14. GLP-1 Market By Region (%): 2013
  • 15. US GLP-1 Market-Victoza® Vs. Other GLP-1(Value, TRx Scripts, % of Diabetes Care): 2010-2013
  • 16. Germany, UK And France Markets for GLP-1: Victoza® Vs. Other GLP-1 Products (Value, % of Diabetes Care): 2009-2013
  • 17. Effects Of Phytochemicals in Insulin Secretion And Pancreatic-Β-cell Apoptosis
  • 18. Cinnamomum verum
  • 19. Cinnamon Trees
  • 20. Cinnamon Products
  • 21. Flow Diagram Of Cinnamon Processing
  • 22. Mechanisms Of Action Of Cinnamon In Relevant Metabolic Pathways
  • 23. Novo Nordisk Diabetes Care Revenues By Segment (DKK Billion): 2013
  • 24. Novo Nordisk MAT Diabetes Care Sales Growth By Segment (%): 2008-2013
  • 25. Novo Nordisk Global And Regional Insulin Market Shares: 2013
  • 26. Novo Nordisk Revenue And Growth By Product and Region: 2009-2013
  • 27. Novo Nordisk Volume Market Share Across Insulin Classes
  • 28. Novo Nordisk Brand Names, Product Types, Sales, Market Shares, Patent Expirations: 2013
  • 29. Novo Nordisk's Modern Insulins Volume Market Share By Segment
  • 30. Novo Nordisk Product Growth And Market Shares By Segment: 2008-2013
  • 31. Novo Nordisk Modern Insulin US Market Share By Market Segment: 2008-2013
  • 32. US Insulin Supplier Volume Market Shares (%): 2013
  • 33. European Insulin Supplier Volume Market Shares (%): 2013
  • 34. Chinese Insulin Supplier Volume Market Shares (%): 2013
  • 35. Japanese Insulin Supplier Volume Market Shares (%): 2013
  • 36. Novo Nordisk Current And Future Product Portfolio
  • 37. Novo Nordisk R&D Pipeline: Diabetes And Obesity
  • 38. Insulin Secretion Profile
  • 39. Insulin Enables Glucose To Become Energy
  • 40. Insulin Level Vs. Time Of Day
  • 41. Diabetes Diagnosis And The Rule Of Halves
  • 42. Glycaemic Control In Selected Countries (%)
  • 43. Diabetes Prevalence And Diagnosis Rates By Region: 2013
  • 44. Main Symptoms of Diabetes
  • 45. Risk Reduction By Class From Lowering HbA1c By 1%-Point
  • 46. Insulin Synthesis Process
  • 47. Insulin Oscillations
  • 48. Idealized Diagram Of Blood Sugar Fluctuation
  • 49. Effect Of Insulin On Glucose Uptake And Metabolism
  • 50. The Structure Of Insulin
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