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エピジェネティクス、多分化能およびリプログラミング市場:2009年

Epigenetics, Pluripotency, and Reprogramming 2009 Market Report

発行 Select Biosciences, Ltd.
出版日 2009年05月 商品コード 94761
ページ情報 英文 139 pages
価格
US$ 2,510 換算 ¥ 202,230 (税抜) PDF by E-mail (Single User License)
US$ 2,790 換算 ¥ 224,790 (税抜) PDF by E-mail (Site License)


原文目次

Abstract

This is the latest and most up-to-date Epigenetics, Cellular Reprogramming, and iPSC Market Analysis Report from Select Biosciences. This comprehensive report provides a thorough discussion and analysis of the emerging epigenetics space and cellular reprogramming and the iPSC phenomenon from both a technical as well as market-focused perspective. Qualitative and quantitative analysis of the epigenetics and pluripotency, hESC, iPSC spaces thorough bottom-up based market trends obtained via detailed market surveys administered by Select Biosciences to a worldwide industry participant pool are presented in this report. All report purchasers receive access to all the raw market data collected via online access to our secure server - allows the report purchasers to query the data in different ways to analyze the various market segments.

This Comprehensive Industry Report Addresses the Technical and Market Landscape of Epigenetics, Reprogramming, and Induced Pluripotent Stem Cells (iPSCs): These are Emerging Areas for which Qualitative and Quantitative Analyses are presented

Extensive Worldwide Technical and Market Analyses Presented in this Report:

  • Technical aspects of Epigenetics: The various modifications that constitute epigenetics, their roles in vivo and experimental methods to detect them
  • Genes that are subject to epigenetic modifications in various disease areas (various cancers, CNS diseases)
  • Epigenetics-based therapeutics: Mechanisms of action, preclinical and clinical trials pipelines (for DNA methylation-based therapeutics, HDAC inhibitors)
  • Commercialized epigenetics-based therapeutics
  • Cellular reprogramming, pluripotency, and iPSCs: Technology trends, in vivo mechanism, experimental manipulation, and emerging trends
  • Results and Analyses from Select Biosciences recent worldwide market surveys focusing upon the qualitative and quantitative trends in epigenetics and pluripotency/hESCs/iPSCs. Areas of coverage include the market penetrance of various hESCs used industry-wide, distribution of the industry with respect to types of epigenetic modifications studied, and emerging market trends in epigenetics and the iPSC spaces. All report purchasers also receive access to the raw market data via online access to secure server
  • More details of the scope of coverage of this industry report are found in the table of contents (TOC) for the report - see below for link to downloadable PDF of the TOC

Table of Contents

Description of Chapters/Topics Covered

Chapter 1 Executive Summary

  • Scope of this market report
  • Developmental potential and epigenetic states of cells are intricately linked
  • Pluripotency - An eppigenetic phenomenon
  • Epigenetic characteristics of somatic and pluripotent cells
  • Proposed mechanisms of cellular reprogramming to create iPSCs
  • Summary of epigenetic modifications and their effects
  • Summary of technologies for assessing and profiling DNA methylation an histone modifications
  • Competitive landscape

Chapter 2 Epigenetics: Central and Essential Role in Differentiation and Disease

  • Mechanisms and consequences of epigenetic modifications
  • DNA and histone modifications that contribute to epigenetic regulation
  • How epigenetic modifications affect gene expression
  • Epigenetic aberrations in different diseases: Genes affected

Chapter 3 Epigenetics market landscape

  • Epigenetics-based therapeutics
  • HDAC inhibitors: Current status and research pipeline
  • Emerging market trends in epigenetic therapeutics
  • Epigenetics market landscape worldwide market survey: Data and analyses
  • Qualitative market trends
  • Quantitative market trends

Chapter 4 Pluripotency, hESCs, Reprogramming, iPSCs: Technical and Market Landscape

  • iPSCs: Potential applications and limitations
  • Small molecules and factors used in cellular reprogramming
  • Methods of factor delivery for cellular reprogramming
  • Pluripotency, hESCs, iPSCs market landscape worldwide market survey: Data and analyses
  • Qualitative market trends
  • Quantitative market trends
  • Usage pattern of various hESC lines from worldwide sources

Appendix 1. Research Methodology

Appendix 2. Global hESC Regulatory Landscape

Appendix 3. Pipeline of Epigenetics Therapeutics

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