Abstract
Overview
Interest in non-coding RNA has exploded in recent years. The diverse function
and roles of microRNA (miRNA) in disease and development has captured the
interest of the research community. The promise of miRNAs serving as useful
biomarkers in clinical diagnostics and therapeutic targets has already led to
several clinical trials, acquisitions, startups and spinouts as companies and
investors look to capitalize on the potential.
Percepta' s MicroRNA Analysis In North America: A Market Research Report For
Life Science Tool Providers takes a close look at the endogenous miRNA
research market in the United States and Canada. This report was developed
through a combination of primary market research of active miRNA researchers
collected in interviews and online questionnaires as well as secondary market
research on the suppliers, technologies, and commercial products. This Trends
& Opportunities in Early Growth Markets report is designed to provide research
tool providers valuable insights into the current miRNA research market and
the technologies driving it.
Highlights of this report include:
- Comprehensive Technology Review
- miRNA Market Insights
- miRNA Researcher Profile
- Overall Market Size and Growth Estimates
- Supplier Opportunities Analysis
The Trends & Opportunities in Early Growth Markets report focuses on the following market sub-segments:
- miRNA Purification
- miRNA Cloning
- miRNA Microarray Labeling
- miRNA Microarrays
- miRNA Sequencing
- miRNA qRT-PCR
- miRNA Functional Analysis: Inhibitors and Over-expression
- miRNA Localization
- miRNA Target Analysis
Participant Demographics for the Online Survey and Telephone Interviews
Participants from the academic, government and commercial market segments are
well represented, with nearly 15% of respondents employed in an industry
setting. The majority (63%) of respondents are currently working at a
University, College, or Medical School. All participants are located in the
United States or Canada.
Participants hold diverse roles at their institutions. Junior (Lab Tech, Grad
Students), mid level (Post-Doc, Lab Manager) and senior (Professor/PI, Group
Leader) scientists are well represented in the data set, with the most cited
job titles being Post-Doctoral Fellow (23%), Senior Scientist (18%) and
Graduate Student (15%). A wide variety of scientific areas of specialization
is also evident, led by Molecular Biology (25%), Cell Biology (12%),
Biochemistry (9%) and Genomics (7%). Participants indicating eighteen
additional scientific areas of specialization comprise the remainder.
Small (1 to 5 scientists), mid-size ( 6 to 10 scientists) and large
laboratories (>10 scientists) are well represented in the respondent data set:
38% of respondents work in labs where 1-5 people regularly perform
experiments, followed by 35% of respondents working in labs where 6-10 people
perform experiments. Larger labs (>10 researchers) account for 27% of
participants.
Table of Contents
- Figures and Tables
- Executive Summary
- Summary of Key Findings
- Technology and Supplier Review
- Non Coding RNA Overview
- miRNA Applications
- Overview of miRNA Analysis Workflow
- miRNA Analysis Techniques and Suppliers
- Supplier Audit and Product Index
- Leading miRNA Suppliers: North American Market Share Overview
- Qualitative End-user Assessment of the miRNA Marketplace
- Survey Methodology and Data Analysis
- Respondent Demographics
- Researcher Profile and miRNA Research Practices
- miRNA Researcher Profile - Primary Sources of Scientific Information
- miRNA Researcher Profile - Sample Types Analyzed for miRNA Studies
- miRNA Researcher Profile - Most Useful Methods in Practice
- miRNA Researcher Profile - Replicates Run Per Assay Type
- miRNA Researcher Profile - Use of Target Prediction Algorithms
- Experimental Frequency, Experimental Growth Rate, And Price Per Reaction
of miRNA Analysis Techniques
- Experimental Frequency of Various miRNA Analysis Techniques
- Projected Growth Rates for Various miRNA Techniques
- Respondent' s Stated Price Per Reaction
- Customer Satisfaction and Interest in Switching Suppliers of miRNA
Analysis Products
- Current Satisfaction with miRNA Analysis Products and Propensity for
Switching Suppliers
- Product Features Important to End Users
- Market Shares by Segment (Share of Mention)
- Share of Mention of Primary Suppliers of miRNA Products by Segment
- Estimated Total Market Size and Growth Rate
- Estimates of North American Market Potential
- Qualitative End-user Assessment of the miRNA Marketplace
- Supplier Opportunity Analysis
- Appendix:
- Verbatim User Insight
- Survey Solicitation
- Survey Questionnaire
LIST OF FIGURES
- Figure 1: miRNA Processing
- Figure 2: miRNA Analysis Flowchart
- Figure 3: Respondent' s Place of Employment
- Figure 4: Respondent' s Country/Region
- Figure 5: Respondent' s Job Title
- Figure 6: Respondent' s Primary Area of Expertise/Specialization
- Figure 7: Number of Employees in Respondent' s Laboratory
- Figure 8: Percent of Respondents that Perform miRNA Experiments
- Figure 9: Preferred Journal of miRNA Researchers
- Figure 10: Preferred Web Site of miRNA Researchers
- Figure 11: Print Versus Online Loyalty Comparison - Nature and Science
- Figure 12: Current and Future Sample Types for miRNA Analysis
- Figure 13: miRNA Techniques that Produce the Most Compelling Data
- Figure 14: Replicate Practices in miRNA Experiments
- Figure 15: Respondent' s Stated Use of miRNA Prediction Algorithms
- Figure 16: Percent Usage of Top miRNA Prediction Algorithms
- Figure 17: Percentage of Respondents Performing Various miRNA Analysis
Techniques at Least a Few Times Per Year
- Figure 18: Most Important Features of miRNA Purification Products
- Figure 19: Most Important Features of miRNA Microarray Platform
- Figure 20: Most Important Features of miRNA qRT-PCR Reagents
- Figure 21: Most Important Features of miRNA Function Analysis Reagents
- Figure 22: Market Share (Share of Mention as Primary Supplier) for miRNA
Isolation/ Purification Products
- Figure 23: Market Share (Share of Mention as Primary Supplier) for miRNA
Cloning/Sub-cloning Products
- Figure 24: Market Share (Share of Mentions as Primary Supplier) for miRNA
Fluorescent Labeling for Microarray
- Figure 25: Market Share (Share of Mentions as Primary Supplier) for miRNA
Sequencing Product
- Figure 26: Market Share (Share of Mentions as Primary Supplier) for miRNA
Northern Blot Products
- Figure 27: Market Share (Share of Mentions as Primary Supplier) for miRNA
Microarray Profiling Products
- Figure 28: Market Share (Share of Mentions as Primary Supplier) for miRNA
qRT-PCR Products
- Figure 29: Market Share (Share of Mentions as Primary Supplier) for miRNA
in situ Hybridization Products
- Figure 30: Market Share (Share of Mentions as Primary Supplier) for miRNA
Over- Expression Products
- Figure 31: Market Share (Share of Mentions as Primary Supplier) for miRNA
Inhibition (Knockdown) Products
- Figure 32: Initial Public Funding Levels and Projected Public Funding
Levels for miRNA In US and EU
- Figure 33: Estimated Industrial Private Fund Expenditures on Consumable
Materials and Reagents For miRNA Discovery and Preclinical Research
- Figure 34: Rates of Peer Reviewed Publications in the Area of miRNA or
Non-coding RNA Research
- Figure 35: Rate of Patent Applications for Technology Relevant to miRNA
since 2002
LIST OF TABLES
- Table 1: miRNA Analysis Market Share Leaders
- Table 2: miRNA Analysis Product Index
- Table 3: Frequency of Performance of Common miRNA Techniques
- Table 4: Number of Experiments Performed Per Month
- Table 5: miRNA Analysis Techniques Estimated Annual Growth Rates
- Table 6: Median and Average Price per Reaction for miRNA Analysis Products
- Table 7: Current Satisfaction and Propensity for Changing Primary Suppliers
- Table 8: Market Size and Growth Estimates - miRNA North America
- Table 9: Supplier Opportunities for miRNA Functional Analysis Products
- Table 10: Supplier Opportunities for miRNA Purification Products
- Table 11: Supplier Opportunities for miRNA Microarray Products
- Table 11: Supplier Opportunities for miRNA qRT-PCR Products
