BI 10773 (Type 2 Diabetes) - Analysis and Forecasts to 2020
Summary
GlobalData's pharmaceuticals report, "BI 10773 (Type 2 Diabetes) - Analysis and Forecasts to 2020" provides BI10773 sales estimates for US, EU5 and Japan. In addition, it covers detailed clinical assessment of the drug, factors impacting drug sales, competitive landscape, and analysis of sales performance during the forecast period (2014-2020). The report also includes information on Type 2 Diabetes market. This report is built using data and information sourced from GlobalData's proprietary databases, primary and secondary research using Company's corporate website, SEC filings, investor presentations and featured press releases, both from company and industry-specific third party sources, put together with in-house analysis, by GlobalData's team of industry experts.
Scope
Therapy area profile including patient population for the US, EU5 and Japan (seven major markets)
Analysis and review of BI10773
Qualitative and quantitative assessment of market space
Analysis of the trends, drivers and restraints shaping and defining the markets
In-depth analysis of BI10773 including efficacy, safety, pricing, competition and other details which influence its sales potential
Detailed sales forecast for 2014-2020 for BI10773 in the seven major markets
Reasons to buy
Understand and capitalize by identifying products that are most likely to ensure a robust return
Stay ahead of competition by understanding the changing competitive landscape
Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential
Make more informed business decisions from insightful and in-depth analysis of the drug's performance
Examine the historical sales performance of a drug in seven major markets
Obtain sales forecast for currently marketed/pipeline drug for 2011-2020 for all seven major markets
TOC
1 Table of Contents
1 Table of Contents 2
1.1 List of Tables 4
1.2 List of Figures 4
2 Introduction 5
2.1 Diabetes 5
2.2 Epidemiology 5
2.2.1 Prevalence 5
2.2.2 Mortality 7
2.3 Etiology and Risk Factors 9
2.3.1 Obesity 9
2.3.2 Sedentary Lifestyle 9
2.3.3 Family History and Genetics 9
2.3.4 Ethnicity 9
2.3.5 Old Age 9
2.4 Economic Impact of Diabetes 9
2.5 GlobalData Report Guidance 11
3 Type 2 Diabetes: Market Characterization 12
3.1 Type 2 Diabetes Market 12
3.2 Type 2 Diabetes Market Forecasts 13
3.3 Type 2 Diabetes Market: Drivers and Restraints 14
3.3.1 Drivers 14
3.3.2 Restraints 15
4 Classification of Diabetes 16
4.1 Types of Diabetes 16
4.1.1 Type 1 Diabetes 16
4.1.2 Type 2 Diabetes 16
4.1.3 Gestational Diabetes 16
4.2 Diabetes Complications 16
4.2.1 Cardiovascular Disease 16
4.2.2 Nephropathy 17
4.2.3 Neuropathy 17
4.2.4 Amputation 17
4.2.5 Retinopathy 17
5 Evolution of Anti-Diabetic Treatments 18
6 Medications 19
6.1 Insulin 19
6.2 Oral Medications 19
6.2.1 Sulfonylureas (SUR) 19
6.2.2 Biguanides (BGDs) 19
6.2.3 Alpha-Glucosidase Inhibitors (AGI) 21
6.2.4 Meglitinides 21
6.2.5 Thiozolidinediones (TZDs) 22
6.2.6 Dipeptidyl Peptidase IV (DPP- 4) Inhibitors 23
6.2.7 Oral Combination Therapy 23
6.3 Other Injectionable Medications 24
6.3.1 Pramlintide 24
6.3.2 Exenatide 24
6.4 Market Share as per Classes in Type 2 Diabetes 24
7 BI 10773 25
7.1 Introduction 25
7.2 Mechanism of Action 25
7.3 Clinical Studies 25
7.3.1 Phase II 25
7.3.2 Phase III 26
7.4 Status of BI 10773 26
7.5 Factors Affecting Sales of BI 10773 26
7.5.1 SGLT2- A New Class of Therapy 26
7.5.2 Competition from Januvia 27
7.5.3 Competition from Dapagliflozin 27
7.6 Drug Evaluation 27
7.6.1 Drug Risk Benefit Score 27
7.6.2 Intensity of Competition 28
7.7 Sales Forecasts 28
7.7.1 Target Patient Pool for BI 10773 28
7.7.2 Dosing 28
7.7.3 Market Penetration 28
7.7.4 Annual Cost of Therapy 29
7.7.5 Sales Projections of BI 10773 30
8 Diabetes Market: Appendix 39
8.1 Market Definitions 39
8.2 List of Abberiviations 39
8.3 Research Methodology 40
8.3.1 Coverage 40
8.3.2 Secondary Research 40
8.3.3 Forecasting 40
8.3.4 Number of patients approved to take the drug 41
8.3.5 Net Penetration of Drug 41
8.3.6 Net Annual Dosing 41
8.3.7 Annual Cost of Therapy 41
8.4 Drug Sales Estimates Model 41
8.5 Contact Us 42
8.6 Disclaimer 42
8.7 Sources 42
List of Tables
1.1 List of Tables
Table 1: Diabetes, World, Prevalence Estimates for the age group 20-79 years (million), 2000-2030 5
Table 2: Diabetes, Top 10 Countries, by Prevalence (million), 2010 and 2030 7
Table 3: Diabetes, Top 10 Countries, Highest Health Expenditures ($bn), 2010 10
Table 4: Type 2 Diabetes, World, Major Marketed Drugs By Sales ($m), 2010 12
Table 5: Type 2 Diabetes, World, Major Pipeline Products in Phase III 13
Table 6: Diabetes, Worldwide, Prevalence Estimates, 2010 and 2030 14
Table 7: Overweight*, Global, Prevalence Estimates in Males Aged 15 and above (%), 2005 15
Table 8: Diabetes Drugs Evolution 18
Table 9: Phase II Results of BI 10773 versus Placebo, and Metformin versus Placebo 26
Table 10: Status of BI 10773 for Type 2 Diabetes 26
Table 11: Drug Risk Benefit Score, BI 10773 27
Table 12: Annual Cost of BI 10773 for Type 2 Diabetes, 2014 29
Table 13: BI 10773, Type 2 Diabetes, Global, Sales Forecasts ($m), 2014-2020 30
Table 14: BI 10773, Type 2 Diabetes, The US, Sales Forecasts ($m), 2014-2020 31
Table 15: BI 10773, Type 2 Diabetes, The UK, Sales Forecasts ($m), 2014-2020 32
Table 16: BI 10773, Type 2 Diabetes, France, Sales Forecasts ($m), 2014-2020 33
Table 17: BI 10773, Type 2 Diabetes, Germany, Sales Forecasts ($m), 2014-2020 34
Table 18: BI 10773, Type 2 Diabetes, Italy, Sales Forecasts ($m), 2014-2020 35
Table 19: BI 10773, Type 2 Diabetes, Spain, Sales Forecasts ($m), 2014-2020 36
Table 20: BI 10773, Type 2 Diabetes, Japan, Sales Forecasts ($m), 2014-2020 37
List of Figures
1.2 List of Figures
Figure 1: Diabetes, World, Comparative Prevalence in Age Group 20-79 years (%), 2010 6
Figure 2: Diabetes, World, Comparative Prevalence in Age Group 20-79 years (%), 2030 6
Figure 3: Diabetes, World, Mortality, 2010 7
Figure 4: Top 10 Causes of Mortality, Worldwide, 2008 8
