The drug delivery industry has in recent years become a key partner for
pharmaceutical companies in their efforts to maximize the patent lives of
successful products. Drug delivery companies not only stand to benefit from
patent expiry by providing their reformulation services to pharmaceutical
companies, but also by producing their own versions of branded products with
improved delivery mechanisms. Thus, post-patent expiry sales can be switched
from the ethical manufacturer to the drug delivery sector.
Drug Delivery Technologies: Current Market Dynamics, Future Market
Opportunities and Lifecycle Strategies is an up-to-date guide that assesses
the current state of the drug delivery industry and its application to both
the pharmaceutical and biotech industries. While the sector is still dominated
by oral technologies, drug delivery systems have expanded to include more
novel devices such as needleless injectables, PEGylation platforms and
microelectromechanical devices. These technological advances extend the
duration of a drug' s action, increase delivery to target sites, reduce
delivery to unwanted sites, and maximize drug absorption.
The expanding market for biotechnology and gene-based products, which by their
very nature are difficult to administer, represents an emerging opportunity
for drug delivery technologies. These technologies are first expected to come
to market as reformulations of existing macromolecular therapies, such as
insulin. This report analyzes the markets for oral, inhalable, injectable,
transmucosal, transdermal and niche drug delivery technologies as they apply
to both biotech and traditional pharmacological compounds.
Key Features of This Report
A thorough overview of both marketed and emerging drug delivery
technologies set to impact the global pharmaceutical market
Analysis of the opportunities and threats to the global drug delivery
industry
Profiles of drug delivery companies along with key financial figures and
technology/product portfolios
Market analysis and outlook for the leading drug delivery technologies,
including oral, injectable, inhalable, transdermal, transmucosal and niche
technologies
Profiles of key emerging drug delivery technologies and profiles of
leading companies, by type of technology
An overview of the global drug delivery market, with sales for key drug
delivery categories and key products within each one of the them
Identification of key areas associated with the successful development of
new drug delivery systems
Critical assessment of market trends, forecasts and problems in the global
drug delivery market
Explanations of key technologies and mechanism of action of new drug
delivery technologies and products utilizing them
Thorough descriptions of important areas of research and development in
the drug delivery market
What questions does this report answer?
What are the key trends in the field of drug delivery as a whole?
What are the major issues involved in the research and development of more
effective drug delivery systems?
What types of drug delivery technologies are currently in research and
development in each of the main drug delivery categories?
What is the value of new drug delivery technologies in terms of a
product' s lifecycle management?
Which new drug delivery systems are likely to provide the best commercial
opportunities for their manufacturers?
Highlights of this report
Discussion and analysis of the problems associated with the use of
traditional drug delivery technologies: lack of patient compliance,
considerable adverse effects, inferior clinical efficacy due to the lack of
targeted delivery
Identification of the hallenges to the development of better, more
efficacious drug delivery technologies, with fewer side effects
Focused analysis of the global market for major drug delivery
technologies: oral, inhalable, injectable, transdermal, transmucosal and
topical, as well as niche technologies, such as gene delivery
Identification of the major products in research and development utilizing
new technologies
Highlights of the drug delivery systems that are most likely to impact the
global market
Reasons to purchase
Provides a comprehensive description of the current state of affairs in
the global drug delivery field
Provides a comprehensive description of the main drug delivery
technologies and key products within each of the categories
Asesses key products and technologies in clinical development
Provides a guide to optimizing drug reformulation processes
Provides a guide to business models of drug delivery companies
Identifies key issues facing drug delivery and pharmaceutical companies in
the development of new drug delivery systems
Table of Contents
1 INTRODUCING THE FIELD OF DRUG DELIVERY 15
1.1 THE VALUE OF DRUG DELIVERY SYSTEMS 15
1.2 DRUG DELIVERY AND PRODUCT DIFFERENTIATION 16
1.3 DRUG DELIVERY AND PATENT EXTENSION 17
1.4 THE OPTIMAL TIME FOR REFORMULATION 19
1.5 OPTIMIZING R&D RETURNS THROUGH DRUG DELIVERY 20
1.6 OPPORTUNITIES AND THREATS TO THE DRUG DELIVERY SECTOR 20
1.6.1 Opportunities for Growth in the Drug Delivery Sector 21
1.6.2 Threats to Additional Growth in the Drug Delivery Sector 24
1.7 BUSINESS MODELS OF DRUG DELIVERY COMPANIES 26
2 AN OVERVIEW OF DRUG DELIVERY TECHNOLOGIES 28
2.1 ORAL DRUG DELIVERY 28
2.1.1 Controlled Release 29
2.1.2 Sustained Release 31
2.1.3 Chronomodulation 31
2.1.4 Rapid Dissolving and Taste-masking Tablets 31
2.1.5 Macromolecular Drug Delivery 33
2.1.6 Microemulsion 33
2.1.7 Pulsatile Drug Delivery 34
2.2 INHALABLE DRUG DELIVERY 35
2.2.1 Nebulizers 36
2.2.2 Metered Dose Inhalers (MDIs) 36
2.2.3 Dry Powder Inhalers (DPIs) 37
2.2.4 Limitations of Pulmonary Delivery Systems for Systemic Delivery 38